Gene: Pou4f2 (POU class 4 homeobox 2) Rattus norvegicus
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Symbol: Pou4f2
Name: POU class 4 homeobox 2
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to oxygen levels; positive regulation of cardiac muscle cell apoptotic process; regulation of gene expression; PARTICIPATES IN p53 signaling pathway; FOUND IN cytoplasm (ortholog); nuclear euchromatin (ortholog); nuclear speck (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; cadmium dichloride
AGR Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding activity, and transcription coregulator activity; involved in several processes, including cellular response to oxygen levels, positive regulation of cardiac muscle cell apoptotic process, and regulation of gene expression; predicted to localize to the cytoplasm, intracellular organelle, and transcription factor complex; orthologous to human POU4F2 (POU class 4 homeobox 2).
Merged Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding activity, and transcription coregulator activity; involved in several processes, including cellular response to oxygen levels, positive regulation of cardiac muscle cell apoptotic process, and regulation of gene expression; predicted to localize to the cytoplasm, intracellular organelle, and transcription factor complex; orthologous to human POU4F2 (POU class 4 homeobox 2); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain-3B; brain-specific homeobox/POU domain protein 3B; Brn-3.2; Brn-3B; Brn3b; POU domain, class 4, transcription factor 2
Orthologs:
Homo sapiens (human) : POU4F2 (POU class 4 homeobox 2)  HGNC  Alliance
Mus musculus (house mouse) : Pou4f2 (POU domain, class 4, transcription factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou4f2 (POU class 4 homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : POU4F2 (POU class 4 homeobox 2)
Canis lupus familiaris (dog) : POU4F2 (POU class 4 homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou4f2 (POU class 4 homeobox 2)
Sus scrofa (pig) : POU4F2 (POU class 4 homeobox 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01933,160,180 - 33,163,821 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01944,051,763 - 44,055,404 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41931,388,907 - 31,392,548 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11931,395,364 - 31,395,583 (+)NCBI
Celera1928,985,198 - 28,988,839 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pou4f2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620075
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.