Gene: Pou4f2 (POU class 4 homeobox 2) Rattus norvegicus
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Symbol: Pou4f2
Name: POU class 4 homeobox 2
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to oxygen levels; positive regulation of cardiac muscle cell apoptotic process; regulation of gene expression; PARTICIPATES IN p53 signaling pathway; FOUND IN cytoplasm (ortholog); nuclear euchromatin (ortholog); nuclear speck (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; cadmium dichloride
AGR Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding activity, and transcription coregulator activity; involved in several processes, including cellular response to oxygen levels, positive regulation of cardiac muscle cell apoptotic process, and regulation of gene expression; predicted to localize to the cytoplasm, intracellular organelle, and transcription factor complex; orthologous to human POU4F2 (POU class 4 homeobox 2).
Merged Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding activity, and transcription coregulator activity; involved in several processes, including cellular response to oxygen levels, positive regulation of cardiac muscle cell apoptotic process, and regulation of gene expression; predicted to localize to the cytoplasm, intracellular organelle, and transcription factor complex; orthologous to human POU4F2 (POU class 4 homeobox 2); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain-3B; brain-specific homeobox/POU domain protein 3B; Brn-3.2; Brn-3B; Brn3b; POU domain, class 4, transcription factor 2
Orthologs:
Homo sapiens (human) : POU4F2 (POU class 4 homeobox 2)  HGNC  Alliance
Mus musculus (house mouse) : Pou4f2 (POU domain, class 4, transcription factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou4f2 (POU class 4 homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : POU4F2 (POU class 4 homeobox 2)
Canis lupus familiaris (dog) : POU4F2 (POU class 4 homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou4f2 (POU class 4 homeobox 2)
Sus scrofa (pig) : POU4F2 (POU class 4 homeobox 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01933,160,180 - 33,163,821 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01944,051,763 - 44,055,404 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41931,388,907 - 31,392,548 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11931,395,364 - 31,395,583 (+)NCBI
Celera1928,985,198 - 28,988,839 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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QTLs in Region (Rnor_6.0)
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Sequence

Nucleotide Sequences
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Strain Sequence Variants (Rnor 5.0)

Additional Information

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Nomenclature History
RGD Curation Notes
  
More on Pou4f2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620075
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.