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Gene: Rbl2 (RB transcriptional corepressor like 2) Rattus norvegicus
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Symbol: Rbl2
Name: RB transcriptional corepressor like 2
Description: Predicted to have RNA polymerase II activating transcription factor binding activity; RNA polymerase II regulatory region DNA binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; negative regulation of gene expression; and regulation of lipid kinase activity. Localizes to the chromatin. Predicted to colocalize with the nucleus. Orthologous to human RBL2 (RB transcriptional corepressor like 2); PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 130 kDa retinoblastoma-associated protein; P130; PPAR-alpha-interacting complex protein 128; PRB2; PRIC128; Rb2; RBR-2; retinoblastoma-like 2; retinoblastoma-like 2 (p130); retinoblastoma-like protein 2; Retinoblastoma-related; Retinoblastoma-related gene; retinoblastoma-related protein 2
Orthologs:
Homo sapiens (human) : RBL2 (RB transcriptional corepressor like 2)  HGNC  Alliance
Mus musculus (house mouse) : Rbl2 (RB transcriptional corepressor like 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rbl2 (RB transcriptional corepressor like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RBL2 (RB transcriptional corepressor like 2)
Canis lupus familiaris (dog) : RBL2 (RB transcriptional corepressor like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rbl2 (RB transcriptional corepressor like 2)
Sus scrofa (pig) : RBL2 (RB transcriptional corepressor like 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01917,300,088 - 17,346,865 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01928,364,200 - 28,410,959 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41917,045,131 - 17,092,597 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11917,049,956 - 17,097,423 (-)NCBI
Celera1915,782,149 - 15,828,852 (-)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Rbl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3541
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.