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Gene: Rbl2 (RB transcriptional corepressor like 2) Rattus norvegicus
Symbol: Rbl2
Name: RB transcriptional corepressor like 2
RGD ID: 3541
Description: Predicted to have RNA polymerase II activating transcription factor binding activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; negative regulation of gene expression; and regulation of lipid kinase activity. Localizes to chromatin. Orthologous to human RBL2 (RB transcriptional corepressor like 2); PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: 130 kDa retinoblastoma-associated protein; P130; PPAR-alpha-interacting complex protein 128; PRB2; PRIC128; Rb2; RBR-2; retinoblastoma-like 2; retinoblastoma-like 2 (p130); retinoblastoma-like protein 2; Retinoblastoma-related; Retinoblastoma-related gene; retinoblastoma-related protein 2
Homo sapiens (human) : RBL2 (RB transcriptional corepressor like 2)  HGNC  Alliance
Mus musculus (house mouse) : Rbl2 (RB transcriptional corepressor like 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rbl2 (RB transcriptional corepressor like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RBL2 (RB transcriptional corepressor like 2)
Canis lupus familiaris (dog) : RBL2 (RB transcriptional corepressor like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rbl2 (RB transcriptional corepressor like 2)
Sus scrofa (pig) : RBL2 (RB transcriptional corepressor like 2)
Chlorocebus sabaeus (African green monkey) : RBL2 (RB transcriptional corepressor like 2)
Heterocephalus glaber (naked mole-rat) : Rbl2 (RB transcriptional corepressor like 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01917,300,088 - 17,346,865 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1917,300,089 - 17,346,808 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01928,364,200 - 28,410,959 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41917,045,131 - 17,092,597 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11917,049,956 - 17,097,423 (-)NCBI
Celera1915,782,149 - 15,828,852 (-)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Rbl2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3541
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.