Gene: Cacna1a (calcium voltage-gated channel subunit alpha1 A) Rattus norvegicus
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Symbol: Cacna1a
Name: calcium voltage-gated channel subunit alpha1 A
Description: ENCODES a protein that exhibits calmodulin binding; high voltage-gated calcium channel activity; voltage-gated calcium channel activity; INVOLVED IN calcium ion import; calcium ion transport; chemical synaptic transmission; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH abnormal gait; ASSOCIATED WITH childhood absence epilepsy; temporal lobe epilepsy; amyotrophic lateral sclerosis (ortholog); FOUND IN integral component of presynaptic active zone membrane; neuronal cell body; perikaryon; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; allethrin
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BccA1; BI; brain calcium channel 1; brain calcium channel I; brain class A; Calcium channel alpha 1A; calcium channel, L type, alpha-1 polypeptide, isoform 4; calcium channel, voltage-dependent, alpha 1A subunit; calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; Cav2.1; LOC688360; rbA-1; RBA-I; similar to Voltage-dependent P/Q-type calcium channel alpha-1A subunit (Voltage-gated calcium channel alpha subunit Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI); voltage-dependent P/Q-type calcium channel subunit alpha-1A; voltage-gated calcium channel subunit alpha Cav2.1
Orthologs:
Homo sapiens (human) : CACNA1A (calcium voltage-gated channel subunit alpha1 A)  HGNC  Alliance
Mus musculus (house mouse) : Cacna1a (calcium channel, voltage-dependent, P/Q type, alpha 1A subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cacna1a (calcium voltage-gated channel subunit alpha1 A)
Pan paniscus (bonobo/pygmy chimpanzee) : CACNA1A (calcium voltage-gated channel subunit alpha1 A)
Canis lupus familiaris (dog) : CACNA1A (calcium voltage-gated channel subunit alpha1 A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cacna1a (calcium voltage-gated channel subunit alpha1 A)
Sus scrofa (pig) : CACNA1A (calcium voltage-gated channel subunit alpha1 A)
more info ...
Allele / Splice: Cacna1agry  
Genetic Models: F344-Scn1am1Kyo.GRY-Cacna1agry/Okym
Is Marker For: Strains:   WTC.GRY-Cacna1agry/Kyo   F344-Scn1am1Kyo.GRY-Cacna1agry/Okym  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01925,453,236 - 25,749,550 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01936,502,533 - 36,727,039 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41925,188,170 - 25,424,495 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11925,194,294 - 25,429,321 (-)NCBI
Celera1923,074,249 - 23,295,970 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

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Nomenclature History
RGD Curation Notes
  
More on Cacna1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2244
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE



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