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Gene: Syt1 (synaptotagmin 1) Rattus norvegicus
Symbol: Syt1
Name: synaptotagmin 1
RGD ID: 3803
Description: Exhibits several functions, including calmodulin binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in several processes, including positive regulation of dopamine secretion; regulation of vesicle-mediated transport; and response to calcium ion. Localizes to several cellular components, including excitatory synapse; neuron projection terminus; and secretory vesicle. Biomarker of visual epilepsy. Orthologous to human SYT1 (synaptotagmin 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: P65; synaptotagmin I; synaptotagmin-1; sytI
Homo sapiens (human) : SYT1 (synaptotagmin 1)  HGNC  Alliance
Mus musculus (house mouse) : Syt1 (synaptotagmin I)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Syt1 (synaptotagmin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SYT1 (synaptotagmin 1)
Canis lupus familiaris (dog) : SYT1 (synaptotagmin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Syt1 (synaptotagmin 1)
Sus scrofa (pig) : SYT1 (synaptotagmin 1)
Chlorocebus sabaeus (African green monkey) : SYT1 (synaptotagmin 1)
Heterocephalus glaber (naked mole-rat) : Syt1 (synaptotagmin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0750,084,063 - 50,638,996 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl750,084,060 - 50,638,798 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0750,097,034 - 50,289,950 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4747,243,375 - 47,795,496 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1747,261,066 - 47,815,950 (-)NCBI
Celera740,680,324 - 41,216,966 (-)NCBICelera
Cytogenetic Map7q21NCBI
RH 3.4 Map7348.01RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Syt1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3803
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.