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Gene: Syt1 (synaptotagmin I) Mus musculus
Symbol: Syt1
Name: synaptotagmin I
RGD ID: 736945
Description: Exhibits several functions, including calcium ion sensor activity; calcium-dependent phospholipid binding activity; and syntaxin-1 binding activity. Involved in modulation of chemical synaptic transmission; neurotransmitter secretion; and regulation of dopamine secretion. Localizes to several cellular components, including glutamatergic synapse; presynaptic membrane; and secretory vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Orthologous to human SYT1 (synaptotagmin 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW124717; G630098F17Rik; p65; synaptotagmin 1; synaptotagmin-1; SytI
Homo sapiens (human) : SYT1 (synaptotagmin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Syt1 (synaptotagmin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Syt1 (synaptotagmin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SYT1 (synaptotagmin 1)
Canis lupus familiaris (dog) : SYT1 (synaptotagmin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Syt1 (synaptotagmin 1)
Sus scrofa (pig) : SYT1 (synaptotagmin 1)
Chlorocebus sabaeus (African green monkey) : SYT1 (synaptotagmin 1)
Heterocephalus glaber (naked mole-rat) : Syt1 (synaptotagmin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3910108,333,511 - 108,846,852 (-)NCBI
GRCm3810108,497,650 - 109,010,980 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10108,497,650 - 109,010,982 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710107,935,305 - 108,447,675 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610107,902,359 - 108,414,729 (-)NCBImm8
Celera10110,439,113 - 110,956,164 (-)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1056.52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Syt1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736945
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.