Anxrr17 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Anxrr17 (Anxiety related response QTL 17) Rattus norvegicus

Symbol: Anxrr17
Name: Anxiety related response QTL 17
RGD ID: 634336
Previously known as: Arr17; open field inner locomotion 2; Ofil2; Aerb2; Anxiety/emotionality related behavior QTL 2
Trait: locomotor behavior trait   (VT:0001392)    
Measurement Type: number of entries into a discrete space in an experimental apparatus   (CMO:0000960)    
LOD Score: 3.66
P Value: Not Available
Variance: Not Available
Inheritance Type: additive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr871,509,236 - 116,977,875RGD_MAPPER_PIPELINE
mRatBN7.27924,703 - 115,097,879RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.072,920,071 - 124,838,025RGD_MAPPER_PIPELINERnor6.0
Rnor_5.072,893,487 - 124,826,707RGDRnor5.0
RGSC_v3.471,786,555 - 121,975,577RGDRGSC3.4
Cross Type: intercross
Strains Crossed: LEW/NIcoCrlf SHR/NIcoCrlf 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Anxrr17Ratanxiety disorder  IAGP 631324 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Anxrr17Ratdecreased anxiety-related response  IAGP 631324 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Anxrr17Ratnumber of entries into a discrete space in an experimental apparatus  IDA 631324 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Anxrr17Ratcontrol condition  IDA 631324 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Anxrr17Ratcenter of open field apparatus  IDA 631324 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Anxrr17RatLEW/NIcoCrlf  IEA 631324 RGD 
Anxrr17RatSHR/NIcoCrlf  IEA 631324 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Anxrr17Ratlocomotor behavior trait  IDA 631324 RGD 


#
Reference Title
Reference Citation
1. Identification of female-specific QTLs affecting an emotionality-related behavior in rats. Ramos A, etal., Mol Psychiatry 1999 Sep;4(5):453-62.
2. Evidence for a female-specific effect of a chromosome 4 locus on anxiety-related behaviors and ethanol drinking in rats. Vendruscolo LF, etal., Genes Brain Behav. 2006 Aug;5(6):441-50.
3. Genetic influences on behavioral and neuroendocrine responses to predator-odor stress in rats. Vendruscolo LF, etal., Neurosci Lett. 2006 Dec 1;409(2):89-94. Epub 2006 Oct 18.


1 to 20 of 1813 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41074591LOC120093526uncharacterized LOC1200935267915888928092Rat
3053Esyt1extended synaptotagmin 17928848946199Rat
7678463Rps23-ps3ribosomal protein S23, pseudogene 37941013941989Rat
1587266Rps15-ps2ribosomal protein S15, pseudogene 27966395966881Rat
1587846Zc3h10zinc finger CCCH type containing 107973415977742Rat
621210Rpl41ribosomal protein L417977885978965Rat
1302994Pa2g4proliferation-associated 2G47984795992264Rat
69323Erbb3erb-b2 receptor tyrosine kinase 379945491015876Rat
9854660Rps27a-ps11ribosomal protein S27a, pseudogene 11710173231017874Rat
1597091Pfdn1-ps1prefoldin subunit 1, pseudogene 1710494451049830Rat
621044Rps26ribosomal protein S26710573321058882Rat
2319157Ikzf4IKAROS family zinc finger 4710632831102940Rat
619994Suoxsulfite oxidase711031491107156Rat
1306489Rab5bRAB5B, member RAS oncogene family711094491128348Rat
41263396LOC120093528uncharacterized LOC120093528711285041130023Rat
70486Cdk2cyclin dependent kinase 2711298781137431Rat
1307513Pmelpremelanosome protein711382021148735Rat
70904Dgkadiacylglycerol kinase, alpha711487341175324Rat
1586629Robld3-ps1roadblock domain containing 3, pseudogene 1711691601169716Rat
1306096Pym1PYM homolog 1, exon junction complex associated factor711777461200899Rat

1 to 20 of 1813 rows
1 to 20 of 1982 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10221D7Arb1722675811322458113450Ratregion
10252D7Mit121367114727471114727581Ratregion
10253D7Wox201447114727449114727593Ratregion
10427D7Wox192577106839225106839474Ratregion
10431D7Wox182507106741074106741295Ratregion
10431D7Wox182507106773255106773476Ratregion
10447D7Wox212717113938271113938544Ratregion
10448D7Mgh32447113915925113916171Ratregion
10449D7Mit161627113886156113886318Ratregion
10472D7Wox301987114321734114321932Ratregion
10764D7Mit2319772228208722282284Ratregion
10880D7Mgh2212475288832652888450Ratregion
10935D7Wox1413179359564793595780Ratregion
10936D7Arb520479359562793595833Ratregion
10937D7Wox1515979359562093595781Ratregion
10938D7Wox2911979359563393595754Ratregion
10939D7Mit2721079359563193595843Ratregion
33915D14Mit1424671602213316022370Ratregion
33915D14Mit1424671711623617116475Ratregion
33969D7Mit423979481108594811326Ratregion
1 to 20 of 1982 rows

Flank 1: (D7Rat127)
Rat AssemblyChrPosition (strand)Source
GRCr87116,977,875 - 116,978,074 (+)Marker Load Pipeline
mRatBN7.27115,097,879 - 115,098,078 (+)MAPPER
Rnor_6.07124,838,025 - 124,838,223NCBI
Rnor_5.07124,826,707 - 124,826,905UniSTS
RGSC_v3.47121,975,578 - 121,975,776UniSTS
RGSC_v3.47121,975,577 - 121,975,776RGD
RGSC_v3.17122,009,808 - 122,010,006RGD
Celera7111,406,383 - 111,406,581UniSTS
RH 3.4 Map7912.1RGD
RH 3.4 Map7912.1UniSTS
RH 2.0 Map7688.7RGD
SHRSP x BN Map766.9399RGD
Cytogenetic Map7q34UniSTS
Peak: (D7Mgh11)
Rat AssemblyChrPosition (strand)Source
GRCr871,740,957 - 1,741,094 (+)Marker Load Pipeline
mRatBN7.271,156,446 - 1,156,583 (+)MAPPER
Rnor_6.073,151,537 - 3,151,673NCBI
Rnor_5.073,124,185 - 3,124,321UniSTS
RGSC_v3.472,026,569 - 2,026,705UniSTS
RGSC_v3.472,026,568 - 2,026,705RGD
RGSC_v3.1289,737,808 - 89,738,090RGD
Celera71,026,718 - 1,026,854UniSTS
Cytogenetic Map7q11UniSTS
Flank 2: (D3Mit11)
Rat AssemblyChrPosition (strand)Source
GRCr871,509,106 - 1,509,236 (+)Marker Load Pipeline
mRatBN7.27924,573 - 924,703 (+)MAPPER
Rnor_6.072,919,942 - 2,920,071NCBI
Rnor_5.072,893,358 - 2,893,487UniSTS
RGSC_v3.471,786,426 - 1,786,555UniSTS
RGSC_v3.471,786,425 - 1,786,555RGD
RGSC_v3.171,786,425 - 1,786,555RGD
Celera7797,734 - 797,863UniSTS


1 to 10 of 107 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
10450828Scl79Serum cholesterol level QTL 793.50.001blood HDL cholesterol amount (VT:0000184)blood low density lipoprotein cholesterol level (CMO:0000053)789867376101773158Rat

1 to 10 of 107 rows


Database
Acc Id
Source(s)
NCBI Gene Anxrr17


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-04-14 Anxrr17  Anxiety related response QTL 17  Arr17    Symbol updated 1299863 APPROVED
2004-09-08 Arr17  Anxiety related response QTL 17  Aerb2  Anxiety/emotionality related behavior QTL 2  Symbol and Name updated 1299863 APPROVED

Note Type Note Reference
qtl_cross_type intercross  
qtl_general female specific; LEW allele associates with the lower locomotion in the center of the open field, an anxiety related behavior 631324
qtl_general phenotypes also explained by a recessive model 631324