Gene: Slc39a4 (solute carrier family 39 member 4) Rattus norvegicus
Analyze
Symbol:
Slc39a4
Name:
solute carrier family 39 member 4
Description:
Predicted to have zinc ion transmembrane transporter activity. Predicted to be involved in several processes, including cellular response to zinc ion starvation; cellular zinc ion homeostasis; and zinc ion import across plasma membrane. Predicted to localize to the apical plasma membrane; endosome; and integral component of plasma membrane. Human ortholog(s) of this gene implicated in acrodermatitis enteropathica. Orthologous to human SLC39A4 (solute carrier family 39 member 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
LOC300051; MGC156705; solute carrier family 39 (zinc transporter), member 4; zinc transporter ZIP4; ZIP-4; zrt- and Irt-like protein 4
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
SLC39A4 (solute carrier family 39 member 4) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Slc39a4 (solute carrier family 39 (zinc transporter), member 4) HGNC
Treefam, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Slc39a4 (solute carrier family 39 member 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
SLC39A4 (solute carrier family 39 member 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
SLC39A4 (solute carrier family 39 member 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Slc39a4 (solute carrier family 39 member 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
SLC39A4 (solute carrier family 39 member 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
SLC39A4 (solute carrier family 39 member 4)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):
Slc39a4 (solute carrier family 39 (zinc transporter), member 4)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
slc39a4 (solute carrier family 39 member 4)
Alliance
DIOPT (Ensembl Compara, OrthoFinder, OrthoInspector, PANTHER, TreeFam)
Caenorhabditis elegans (roundworm):
zipt-17
Alliance
DIOPT (Ensembl Compara, PhylomeDB, TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 7 117,675,718 - 117,682,586 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 7 117,675,720 - 117,680,004 (-) Ensembl Rnor_5.0 7 117,663,813 - 117,667,986 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 7 114,661,925 - 114,666,098 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 7 114,696,147 - 114,700,327 (-) NCBI Celera 7 104,683,583 - 104,687,756 (-) NCBI Celera Cytogenetic Map 7 q34 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
acrodermatitis enteropathica ISO RGD:1315470 8554872 ClinVar Annotator: match by term: Hereditary acrodermatitis enteropathica ClinVar PMID:24033266 , PMID:25741868 acrodermatitis enteropathica ISO RGD:1315470 8554872 ClinVar Annotator: match by OMIM:201100 ClinVar PMID:12032886 acrodermatitis enteropathica ISO RGD:1315470 8554872 ClinVar Annotator: match by OMIM:201100 ClinVar PMID:11035780 , PMID:12068297 acrodermatitis enteropathica ISO RGD:1315470 8554872 ClinVar Annotator: match by OMIM:201100 ClinVar PMID:11254458 , PMID:12032886 acrodermatitis enteropathica ISO RGD:1315470 8554872 ClinVar Annotator: match by OMIM:201100 ClinVar PMID:12068297 acrodermatitis enteropathica ISO RGD:1315470 8554872 ClinVar Annotator: match by OMIM:201100 ClinVar PMID:12787121 acrodermatitis enteropathica ISO RGD:1315470 8554872 ClinVar Annotator: match by term: Hereditary acrodermatitis enteropathica ClinVar PMID:25741868 acrodermatitis enteropathica ISO RGD:1315470 8554872 ClinVar Annotator: match by term: Hereditary acrodermatitis enteropathica ClinVar PMID:24033266 acrodermatitis enteropathica ISO RGD:1315470 8554872 ClinVar Annotator: match by term: Hereditary acrodermatitis enteropathica ClinVar autosomal recessive limb-girdle muscular dystrophy type 2Q ISO RGD:1315470 8554872 ClinVar Annotator: match by term: Limb-girdle muscular dystrophy, type 2Q ClinVar PMID:28492532 Brown-Vialetto-Van Laere Syndrome 2 ISO RGD:1315470 8554872 ClinVar Annotator: match by term: Brown-Vialetto-Van Laere syndrome 2 ClinVar PMID:28492532 epidermolysis bullosa simplex Ogna type ISO RGD:1315470 8554872 ClinVar Annotator: match by term: Epidermolysis bullosa simplex, Ogna type ClinVar PMID:28492532 epidermolysis bullosa simplex with muscular dystrophy ISO RGD:1315470 8554872 ClinVar Annotator: match by term: EPIDERMOLYSIS BULLOSA SIMPLEX AND LIMB-GIRDLE MUSCULAR DYSTROPHY ClinVar PMID:28492532 Epidermolysis Bullosa Simplex with Nail Dystrophy ISO RGD:1315470 8554872 ClinVar Annotator: match by term: Epidermolysis bullosa simplex with nail dystrophy ClinVar PMID:28492532 Epidermolysis Bullosa Simplex With Pyloric Atresia ISO RGD:1315470 8554872 ClinVar Annotator: match by term: EBS WITH PYLORIC ATRESIA ClinVar PMID:28492532 junctional epidermolysis bullosa with pyloric atresia ISO RGD:1315470 8554872 ClinVar Annotator: match by term: Epidermolysis Bullosa with Pyloric Atresia ClinVar PMID:28492532
Imported Annotations - CTD
acrodermatitis ISO RGD:1315470 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16714095 more ... acrodermatitis enteropathica ISO RGD:1315470 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12068297 more ... Neoplasm Metastasis ISO RGD:1315470 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:20957146 Prenatal Injuries ISO RGD:1315470 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17483098 respiratory allergy ISO RGD:1315470 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17085522 Imported Annotations - OMIM
acrodermatitis enteropathica ISO RGD:1315470 7240710 OMIM
(-)-epigallocatechin 3-gallate increases expression ISO RGD:1315470 6480464 epigallocatechin gallate results in increased expression of SLC39A4 mRNA CTD PMID:20471814 17beta-estradiol increases expression ISO RGD:1552511 6480464 Estradiol results in increased expression of SLC39A4 mRNA CTD PMID:15289156 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SLC39A4 mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1315470 6480464 Tetrachlorodibenzodioxin results in increased expression of SLC39A4 mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1552511 6480464 Tetrachlorodibenzodioxin affects the expression of SLC39A4 mRNA CTD PMID:21570461 4,4'-diaminodiphenylmethane decreases expression ISO RGD:1552511 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of SLC39A4 mRNA CTD PMID:18648102 4-hydroxyphenyl retinamide increases expression ISO RGD:1552511 6480464 Fenretinide results in increased expression of SLC39A4 mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of SLC39A4 mRNA CTD PMID:22504374 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SLC39A4 mRNA CTD PMID:24780913 actinomycin D multiple interactions ISO RGD:1552511 6480464 Dactinomycin inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA], Dactinomycin inhibits the reaction [Zinc results in decreased expression of SLC39A4 mRNA] CTD PMID:18020946 ammonium chloride multiple interactions ISO RGD:1315470 6480464 Ammonium Chloride inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] CTD PMID:17202136 arsane affects methylation ISO RGD:1315470 6480464 Arsenic affects the methylation of SLC39A4 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1315470 6480464 Arsenic affects the methylation of SLC39A4 gene CTD PMID:25304211 arsenic(3+) affects methylation ISO RGD:1315470 6480464 Arsenic affects the methylation of SLC39A4 gene CTD PMID:25304211 benzo[a]pyrene increases expression ISO RGD:1315470 6480464 Benzo(a)pyrene results in increased expression of SLC39A4 mRNA CTD PMID:20106945 benzo[a]pyrene increases expression ISO RGD:1552511 6480464 Benzo(a)pyrene results in increased expression of SLC39A4 mRNA CTD PMID:27195522 benzo[a]pyrene decreases expression ISO RGD:1552511 6480464 Benzo(a)pyrene results in decreased expression of SLC39A4 mRNA CTD PMID:22228805 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1552511 6480464 Diethylhexyl Phthalate results in decreased expression of SLC39A4 mRNA CTD PMID:19850644 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SLC39A4 mRNA CTD PMID:25181051 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of SLC39A4 mRNA CTD PMID:25653005 cadmium dichloride affects expression EXP 6480464 Cadmium Chloride affects the expression of SLC39A4 mRNA CTD PMID:22110744 cadmium dichloride multiple interactions EXP 6480464 zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A4 mRNA] CTD PMID:25653005 calcitriol decreases expression ISO RGD:1315470 6480464 Calcitriol results in decreased expression of SLC39A4 mRNA CTD PMID:20089671 cannabidiol increases expression ISO RGD:1552511 6480464 Cannabidiol results in increased expression of SLC39A4 mRNA CTD PMID:21542829 , PMID:22178458 carbon nanotube decreases expression ISO RGD:1552511 6480464 Nanotubes, Carbon analog results in decreased expression of SLC39A4 mRNA CTD PMID:25620056 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of SLC39A4 mRNA CTD PMID:18500788 cisplatin increases expression ISO RGD:1315470 6480464 Cisplatin results in increased expression of SLC39A4 mRNA CTD PMID:24280081 cisplatin increases expression ISO RGD:1552511 6480464 Cisplatin results in increased expression of SLC39A4 mRNA CTD PMID:24280081 cobalt dichloride decreases expression ISO RGD:1315470 6480464 cobaltous chloride results in decreased expression of SLC39A4 mRNA CTD PMID:19376846 coumestrol increases expression ISO RGD:1315470 6480464 Coumestrol results in increased expression of SLC39A4 mRNA CTD PMID:19167446 cycloheximide multiple interactions ISO RGD:1552511 6480464 Cycloheximide inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA], Cycloheximide inhibits the reaction [Zinc results in decreased expression of SLC39A4 mRNA] CTD PMID:18020946 cyclosporin A decreases expression ISO RGD:1315470 6480464 Cyclosporine results in decreased expression of SLC39A4 mRNA CTD PMID:25562108 cyclosporin A decreases methylation ISO RGD:1315470 6480464 Cyclosporine results in decreased methylation of SLC39A4 promoter CTD PMID:27989131 dextran sulfate multiple interactions ISO RGD:1552511 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC39A4 mRNA CTD PMID:29950665 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of SLC39A4 mRNA CTD PMID:21266533 diethylstilbestrol decreases expression ISO RGD:1552511 6480464 Diethylstilbestrol results in decreased expression of SLC39A4 mRNA CTD PMID:17394237 diethylstilbestrol increases expression ISO RGD:1552511 6480464 Diethylstilbestrol results in increased expression of SLC39A4 mRNA CTD PMID:15289156 dioxygen multiple interactions ISO RGD:1552511 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SLC39A4 mRNA CTD PMID:30529165 ethyl methanesulfonate decreases expression ISO RGD:1315470 6480464 Ethyl Methanesulfonate results in decreased expression of SLC39A4 mRNA CTD PMID:23649840 formaldehyde decreases expression ISO RGD:1315470 6480464 Formaldehyde results in decreased expression of SLC39A4 mRNA CTD PMID:23649840 furan increases methylation EXP 6480464 furan results in increased methylation of SLC39A4 gene CTD PMID:22079235 genistein increases expression ISO RGD:1552511 6480464 Genistein results in increased expression of SLC39A4 mRNA CTD PMID:15289156 hydrogen peroxide affects expression ISO RGD:1315470 6480464 Hydrogen Peroxide affects the expression of SLC39A4 mRNA CTD PMID:20044591 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of SLC39A4 mRNA CTD PMID:21396975 irinotecan affects expression EXP 6480464 Irinotecan affects the expression of SLC39A4 mRNA CTD PMID:20097248 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of SLC39A4 mRNA CTD PMID:22641619 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of SLC39A4 mRNA CTD PMID:24136188 methimazole increases expression EXP 6480464 Methimazole results in increased expression of SLC39A4 mRNA CTD PMID:22504374 methyl beta-cyclodextrin multiple interactions ISO RGD:1315470 6480464 methyl-beta-cyclodextrin inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] CTD PMID:17202136 methyl methanesulfonate decreases expression ISO RGD:1315470 6480464 Methyl Methanesulfonate results in decreased expression of SLC39A4 mRNA CTD PMID:23649840 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO RGD:1315470 6480464 N more ... CTD PMID:19083439 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO RGD:1552511 6480464 N more ... CTD PMID:18020946 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:1315470 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] CTD PMID:17202136 N-nitrosodiethylamine increases expression ISO RGD:1552511 6480464 Diethylnitrosamine results in increased expression of SLC39A4 mRNA CTD PMID:24535843 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of SLC39A4 mRNA CTD PMID:22110744 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of SLC39A4 mRNA CTD PMID:24136188 oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of SLC39A4 mRNA CTD PMID:23439660 phenobarbital increases expression ISO RGD:1552511 6480464 Phenobarbital results in increased expression of SLC39A4 mRNA CTD PMID:19482888 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of SLC39A4 mRNA CTD PMID:28520973 phenobarbital multiple interactions ISO RGD:1552511 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of SLC39A4 mRNA] CTD PMID:19482888 pirinixic acid decreases expression ISO RGD:1552511 6480464 pirinixic acid results in decreased expression of SLC39A4 mRNA CTD PMID:17426115 progesterone affects expression ISO RGD:1552511 6480464 Progesterone affects the expression of SLC39A4 mRNA CTD PMID:17251523 propiconazole decreases expression ISO RGD:1552511 6480464 propiconazole results in decreased expression of SLC39A4 mRNA CTD PMID:21278054 quercetin increases expression ISO RGD:1315470 6480464 Quercetin results in increased expression of SLC39A4 mRNA CTD PMID:21632981 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of SLC39A4 mRNA CTD PMID:19013527 rotenone increases expression ISO RGD:1315470 6480464 Rotenone results in increased expression of SLC39A4 mRNA CTD PMID:29955902 silver atom increases expression ISO RGD:1552511 6480464 Silver results in increased expression of SLC39A4 mRNA CTD PMID:27131904 silver(0) increases expression ISO RGD:1552511 6480464 Silver results in increased expression of SLC39A4 mRNA CTD PMID:27131904 silver(1+) increases expression ISO RGD:1552511 6480464 Silver results in increased expression of SLC39A4 mRNA CTD PMID:27131904 sodium arsenate decreases expression ISO RGD:1552511 6480464 sodium arsenate results in decreased expression of SLC39A4 mRNA CTD PMID:21795629 sucrose multiple interactions ISO RGD:1315470 6480464 Sucrose inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] CTD PMID:17202136 titanium dioxide multiple interactions ISO RGD:1552511 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC39A4 mRNA CTD PMID:29950665 valproic acid decreases expression ISO RGD:1315470 6480464 Valproic Acid results in decreased expression of SLC39A4 mRNA CTD PMID:29154799 valproic acid increases methylation ISO RGD:1315470 6480464 Valproic Acid results in increased methylation of SLC39A4 gene CTD PMID:29154799 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of SLC39A4 mRNA CTD PMID:19015723 zinc atom multiple interactions ISO RGD:1315470 6480464 Ammonium Chloride inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] more ... CTD PMID:17202136 zinc atom increases expression ISO RGD:1552511 6480464 Zinc deficiency results in increased expression of SLC39A4 mRNA, Zinc deficiency results in increased expression of SLC39A4 protein CTD PMID:12801924 more ... zinc atom affects localization ISO RGD:1552511 6480464 Zinc affects the localization of SLC39A4 protein, Zinc deficiency affects the localization of SLC39A4 protein CTD PMID:12801924 more ... zinc atom increases response to substance ISO RGD:1552511 6480464 SLC39A4 gene mutant form results in increased susceptibility to Zinc deficiency CTD PMID:17483098 zinc atom increases uptake ISO RGD:1552511 6480464 SLC39A4 protein results in increased uptake of Zinc CTD PMID:12801924 more ... zinc atom decreases expression ISO RGD:1315470 6480464 Zinc results in decreased expression of SLC39A4 mRNA, Zinc results in decreased expression of SLC39A4 protein CTD PMID:15753530 , PMID:17202136 zinc atom multiple interactions ISO RGD:1552511 6480464 Cycloheximide inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA] more ... CTD PMID:12801924 , PMID:18020946 zinc atom affects expression ISO RGD:1315470 6480464 Zinc affects the expression of SLC39A4 protein CTD PMID:20479680 zinc atom decreases expression ISO RGD:1552511 6480464 Zinc deficiency results in decreased expression of SLC39A4 mRNA more ... CTD PMID:12514265 more ... zinc atom affects expression ISO RGD:1552511 6480464 Zinc affects the expression of SLC39A4 mRNA CTD PMID:16682017 zinc atom increases uptake ISO RGD:1315470 6480464 SLC39A4 protein results in increased uptake of Zinc CTD PMID:17202136 zinc atom increases transport ISO RGD:1315470 6480464 SLC39A4 protein results in increased transport of Zinc CTD PMID:18326752 zinc dichloride multiple interactions ISO RGD:1315470 6480464 zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in increased expression of SLC39A4 mRNA] CTD PMID:20471814 zinc dichloride multiple interactions EXP 6480464 zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A4 mRNA] CTD PMID:25653005 zinc dichloride decreases expression ISO RGD:1315470 6480464 zinc chloride results in decreased expression of SLC39A4 mRNA CTD PMID:20471814 zinc(0) multiple interactions ISO RGD:1315470 6480464 Ammonium Chloride inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] more ... CTD PMID:17202136 zinc(0) increases transport ISO RGD:1315470 6480464 SLC39A4 protein results in increased transport of Zinc CTD PMID:18326752 zinc(0) increases uptake ISO RGD:1315470 6480464 SLC39A4 protein results in increased uptake of Zinc CTD PMID:17202136 zinc(0) affects expression ISO RGD:1552511 6480464 Zinc affects the expression of SLC39A4 mRNA CTD PMID:16682017 zinc(0) decreases expression ISO RGD:1552511 6480464 Zinc deficiency results in decreased expression of SLC39A4 mRNA more ... CTD PMID:12514265 more ... zinc(0) increases response to substance ISO RGD:1552511 6480464 SLC39A4 gene mutant form results in increased susceptibility to Zinc deficiency CTD PMID:17483098 zinc(0) affects expression ISO RGD:1315470 6480464 Zinc affects the expression of SLC39A4 protein CTD PMID:20479680 zinc(0) multiple interactions ISO RGD:1552511 6480464 Cycloheximide inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA] more ... CTD PMID:12801924 , PMID:18020946 zinc(0) decreases expression ISO RGD:1315470 6480464 Zinc results in decreased expression of SLC39A4 mRNA, Zinc results in decreased expression of SLC39A4 protein CTD PMID:15753530 , PMID:17202136 zinc(0) increases uptake ISO RGD:1552511 6480464 SLC39A4 protein results in increased uptake of Zinc CTD PMID:12801924 more ... zinc(0) affects localization ISO RGD:1552511 6480464 Zinc affects the localization of SLC39A4 protein, Zinc deficiency affects the localization of SLC39A4 protein CTD PMID:12801924 more ... zinc(0) increases expression ISO RGD:1552511 6480464 Zinc deficiency results in increased expression of SLC39A4 mRNA, Zinc deficiency results in increased expression of SLC39A4 protein CTD PMID:12801924 more ...
Biological Process biological_process ND 1598407 1/2007: no relevant rat data RGD cellular response to zinc ion starvation ISO RGD:1552511 1624291 (MGI:MGI:3522410, PMID:15358787) RGD MGI:MGI:3522410 , PMID:15358787 cellular response to zinc ion starvation IEA UniProtKB:Q78IQ7 , ensembl:ENSMUSP000001554421600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular zinc ion homeostasis ISO RGD:1552511 1624291 (MGI:MGI:3028750, PMID:14612438) RGD MGI:MGI:3028750 , PMID:14612438 cellular zinc ion homeostasis IBA FB:FBgn0036461 more ... 13792537 PMID:21873635 GO_Central signal transduction IBA MGI:MGI:2139274 , PANTHER:PTN001742843 13792537 PMID:21873635 GO_Central zinc ion import across plasma membrane IBA FB:FBgn0036461 more ... 13792537 PMID:21873635 GO_Central zinc ion transmembrane transport IEA GO:0005385 1600115 GO_REF:0000108 GOC GO_REF:0000108 zinc ion transport ISO RGD:1552511 1624291 (MGI:MGI:2684332 more ... RGD MGI:MGI:2684332 more ... Cellular Component apical plasma membrane ISO RGD:1552511 1624291 (MGI:MGI:2684332 more ... RGD MGI:MGI:2684332 more ... apical plasma membrane IEA UniProtKB:Q78IQ7 , ensembl:ENSMUSP000001554421600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell IEA GO:0006882 1600115 GO_REF:0000108 GOC GO_REF:0000108 cellular_component ND 1598407 1/2007: no relevant rat data RGD cytoplasmic vesicle ISO RGD:1315470 1624291 (PMID:14612438) RGD PMID:14612438 cytoplasmic vesicle IEA UniProtKB:Q6P5W5 , ensembl:ENSP000003013051600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytoplasmic vesicle ISS UniProtKB:Q6P5W5 1600115 GO_REF:0000024 UniProt GO_REF:0000024 cytoplasmic vesicle ISO RGD:1552511 1624291 (MGI:MGI:3028750, PMID:14612438) RGD MGI:MGI:3028750 , PMID:14612438 endosome ISO RGD:1552511 1624291 (MGI:MGI:3028750, PMID:14612438) RGD MGI:MGI:3028750 , PMID:14612438 integral component of membrane IEA UniProtKB-KW:KW-0812 1600115 GO_REF:0000038 UniProt GO_REF:0000038 integral component of plasma membrane IBA FB:FBgn0024236 more ... 13792537 PMID:21873635 GO_Central plasma membrane ISO RGD:1315470 1624291 (PMID:14612438) RGD PMID:14612438 plasma membrane ISS UniProtKB:Q6P5W5 1600115 GO_REF:0000024 UniProt GO_REF:0000024 plasma membrane ISO RGD:1552511 1624291 (MGI:MGI:3028750, PMID:14612438) RGD MGI:MGI:3028750 , PMID:14612438 recycling endosome membrane IEA UniProtKB-SubCell:SL-0231 1600115 GO_REF:0000039 UniProt GO_REF:0000039 Molecular Function molecular_function ND 1598407 1/2007: no relevant rat data RGD zinc ion transmembrane transporter activity ISO RGD:1552511 1624291 (MGI:MGI:2684332 more ... RGD MGI:MGI:2684332 more ... zinc ion transmembrane transporter activity IBA FB:FBgn0024236 more ... 13792537 PMID:21873635 GO_Central zinc ion transmembrane transporter activity IEA UniProtKB:Q6P5W5 , ensembl:ENSP000003013051600115 GO_REF:0000107 Ensembl GO_REF:0000107 zinc ion transmembrane transporter activity ISO RGD:1315470 1624291 (PMID:22242765) RGD PMID:22242765
Gene-Chemical Interaction Annotations
