Osbpl8 (oxysterol binding protein-like 8) - Rat Genome Database

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Gene: Osbpl8 (oxysterol binding protein-like 8) Rattus norvegicus
Analyze
Symbol: Osbpl8
Name: oxysterol binding protein-like 8
RGD ID: 1561474
Description: Predicted to enable several functions, including cholesterol binding activity; phosphatidylserine transfer activity; and phospholipid binding activity. Predicted to be involved in several processes, including activation of protein kinase B activity; negative regulation of sequestering of triglyceride; and positive regulation of glucose import. Predicted to act upstream of or within negative regulation of cell migration; positive regulation of signal transduction; and protein localization to nuclear pore. Predicted to be located in cortical endoplasmic reticulum and nuclear membrane. Predicted to be active in cytosol; intracellular membrane-bounded organelle; and membrane. Orthologous to human OSBPL8 (oxysterol binding protein like 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC314824; LOC314824; oxysterol-binding protein-related protein 8; RGD1561474; similar to oxysterol-binding protein-like protein 8 isoform a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2746,596,944 - 46,749,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,596,983 - 46,749,888 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx748,496,671 - 48,649,451 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0750,699,816 - 50,852,600 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0750,477,574 - 50,630,354 (+)NCBIRnor_WKY
Rnor_6.0753,878,906 - 54,030,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,878,610 - 54,027,892 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0753,888,262 - 54,039,874 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4750,308,713 - 50,313,369 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera743,400,573 - 43,550,915 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17428193   PMID:19946888   PMID:21441927   PMID:22683860   PMID:23028956   PMID:23812417   PMID:26206935  


Genomics

Comparative Map Data
Osbpl8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2746,596,944 - 46,749,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,596,983 - 46,749,888 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx748,496,671 - 48,649,451 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0750,699,816 - 50,852,600 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0750,477,574 - 50,630,354 (+)NCBIRnor_WKY
Rnor_6.0753,878,906 - 54,030,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,878,610 - 54,027,892 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0753,888,262 - 54,039,874 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4750,308,713 - 50,313,369 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera743,400,573 - 43,550,915 (+)NCBICelera
Cytogenetic Map7q22NCBI
OSBPL8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381276,351,797 - 76,559,771 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1276,351,797 - 76,559,809 (-)EnsemblGRCh38hg38GRCh38
GRCh371276,745,577 - 76,953,551 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361275,269,708 - 75,477,720 (-)NCBINCBI36Build 36hg18NCBI36
Build 341275,248,047 - 75,456,057NCBI
Celera1276,411,526 - 76,618,915 (-)NCBICelera
Cytogenetic Map12q21.2NCBI
HuRef1273,797,739 - 74,006,667 (-)NCBIHuRef
CHM1_11276,711,170 - 76,919,193 (-)NCBICHM1_1
T2T-CHM13v2.01276,329,717 - 76,537,711 (-)NCBIT2T-CHM13v2.0
Osbpl8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910111,000,663 - 111,133,110 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10111,000,613 - 111,133,110 (+)EnsemblGRCm39 Ensembl
GRCm3810111,164,742 - 111,297,249 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10111,164,752 - 111,297,249 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710110,601,858 - 110,734,303 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610110,568,912 - 110,701,357 (+)NCBIMGSCv36mm8
Celera10113,097,050 - 113,230,968 (+)NCBICelera
Cytogenetic Map10D1NCBI
Osbpl8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540515,577,003 - 15,728,983 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540515,577,003 - 15,728,983 (-)NCBIChiLan1.0ChiLan1.0
OSBPL8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11276,720,276 - 76,927,919 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1276,720,276 - 76,820,830 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01273,870,094 - 74,078,073 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
OSBPL8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11519,339,385 - 19,441,583 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1519,142,987 - 19,637,708 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1519,824,481 - 19,967,789 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01519,678,921 - 19,822,002 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1519,678,364 - 19,822,062 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11519,279,309 - 19,422,482 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01519,337,403 - 19,480,483 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01519,465,384 - 19,608,478 (-)NCBIUU_Cfam_GSD_1.0
Osbpl8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494540,920,929 - 41,081,896 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365684,646,426 - 4,806,308 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365684,646,409 - 4,806,283 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSBPL8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl539,568,150 - 39,744,642 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1539,568,136 - 39,744,655 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2543,258,249 - 43,435,452 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OSBPL8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11171,927,862 - 72,142,631 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1171,927,688 - 72,141,587 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037173,404,092 - 173,620,551 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Osbpl8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475021,569,352 - 21,757,660 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Osbpl8
487 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:158
Count of miRNA genes:126
Interacting mature miRNAs:138
Transcripts:ENSRNOT00000058589
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat

Markers in Region
D7Rat147  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,599,531 - 46,599,681 (+)MAPPERmRatBN7.2
Rnor_6.0753,881,455 - 53,881,604NCBIRnor6.0
Rnor_5.0753,890,984 - 53,891,133UniSTSRnor5.0
RGSC_v3.4750,163,959 - 50,164,849RGDRGSC3.4
RGSC_v3.4750,164,660 - 50,164,809UniSTSRGSC3.4
RGSC_v3.4750,164,126 - 50,164,809UniSTSRGSC3.4
RGSC_v3.1750,185,102 - 50,185,251RGD
RH 3.4 Map7394.4RGD
RH 3.4 Map7394.4UniSTS
RH 2.0 Map7361.8RGD
SHRSP x BN Map729.74RGD
Cytogenetic Map7q21UniSTS
D7Uwm11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,595,874 - 46,596,030 (+)MAPPERmRatBN7.2
Rnor_6.0753,877,799 - 53,877,954NCBIRnor6.0
Rnor_5.0753,887,328 - 53,887,483UniSTSRnor5.0
RGSC_v3.4750,160,469 - 50,160,625RGDRGSC3.4
RGSC_v3.4750,160,470 - 50,160,625UniSTSRGSC3.4
RGSC_v3.1750,180,911 - 50,181,067RGD
Celera743,399,467 - 43,399,621UniSTS
Cytogenetic Map7q21UniSTS
RH130422  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,749,378 - 46,749,592 (+)MAPPERmRatBN7.2
Rnor_6.0754,029,601 - 54,029,814NCBIRnor6.0
Rnor_5.0754,167,511 - 54,167,724UniSTSRnor5.0
Rnor_5.0754,039,365 - 54,039,578UniSTSRnor5.0
RGSC_v3.4750,316,140 - 50,316,353UniSTSRGSC3.4
Celera743,550,406 - 43,550,619UniSTS
RH 3.4 Map7391.0UniSTS
Cytogenetic Map7q21UniSTS
BF405318  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map7387.8UniSTS
Cytogenetic Map7q21UniSTS
AU047198  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0753,908,202 - 53,908,380NCBIRnor6.0
Rnor_5.0753,917,966 - 53,918,144UniSTSRnor5.0
RGSC_v3.4750,191,528 - 50,191,706UniSTSRGSC3.4
Celera743,429,059 - 43,429,237UniSTS
Cytogenetic Map7q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 40 30 14 19 14 3 3 74 35 41 11 3
Low 3 3 27 27 27 5 7 5
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000058589   ⟹   ENSRNOP00000055387
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl754,021,832 - 54,026,789 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091910   ⟹   ENSRNOP00000070347
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,596,983 - 46,749,888 (+)Ensembl
Rnor_6.0 Ensembl753,878,610 - 54,027,892 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097311   ⟹   ENSRNOP00000085965
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,648,508 - 46,749,888 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100604   ⟹   ENSRNOP00000085930
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,689,051 - 46,749,888 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101432   ⟹   ENSRNOP00000090337
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,684,097 - 46,749,888 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112719   ⟹   ENSRNOP00000079217
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,672,009 - 46,749,888 (+)Ensembl
RefSeq Acc Id: NM_001309455   ⟹   NP_001296384
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2746,596,983 - 46,749,888 (+)NCBI
Rnor_6.0753,878,906 - 54,030,110 (+)NCBI
Celera743,400,573 - 43,550,915 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594846   ⟹   XP_017450335
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2746,684,570 - 46,749,888 (+)NCBI
Rnor_6.0753,969,162 - 54,030,110 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079120   ⟹   XP_038935048
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2746,596,944 - 46,749,888 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001296384   ⟸   NM_001309455
- UniProtKB: A0A0G2JXN8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450335   ⟸   XM_017594846
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GDH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000055387   ⟸   ENSRNOT00000058589
RefSeq Acc Id: ENSRNOP00000070347   ⟸   ENSRNOT00000091910
RefSeq Acc Id: XP_038935048   ⟸   XM_039079120
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000090337   ⟸   ENSRNOT00000101432
RefSeq Acc Id: ENSRNOP00000085930   ⟸   ENSRNOT00000100604
RefSeq Acc Id: ENSRNOP00000079217   ⟸   ENSRNOT00000112719
RefSeq Acc Id: ENSRNOP00000085965   ⟸   ENSRNOT00000097311
Protein Domains
PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JXN8-F1-model_v2 AlphaFold A0A0G2JXN8 1-888 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695196
Promoter ID:EPDNEW_R5713
Type:initiation region
Name:Osbpl8_1
Description:oxysterol binding protein-like 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0753,878,688 - 53,878,748EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561474 AgrOrtholog
BioCyc Gene G2FUF-34130 BioCyc
Ensembl Genes ENSRNOG00000026962 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000070347 ENTREZGENE
  ENSRNOP00000070347.1 UniProtKB/TrEMBL
  ENSRNOP00000079217 ENTREZGENE
  ENSRNOP00000079217.1 UniProtKB/TrEMBL
  ENSRNOP00000085930 ENTREZGENE
  ENSRNOP00000085930.1 UniProtKB/TrEMBL
  ENSRNOP00000085965.1 UniProtKB/TrEMBL
  ENSRNOP00000090337.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000091910 ENTREZGENE
  ENSRNOT00000091910.2 UniProtKB/TrEMBL
  ENSRNOT00000097311.1 UniProtKB/TrEMBL
  ENSRNOT00000100604 ENTREZGENE
  ENSRNOT00000100604.1 UniProtKB/TrEMBL
  ENSRNOT00000101432.1 UniProtKB/TrEMBL
  ENSRNOT00000112719 ENTREZGENE
  ENSRNOT00000112719.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro OSBP_sf UniProtKB/TrEMBL
  Oxysterol-bd UniProtKB/TrEMBL
  Oxysterol-bd_CS UniProtKB/TrEMBL
  PH/PTB_dom UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report rno:314824 UniProtKB/TrEMBL
NCBI Gene 314824 ENTREZGENE
PANTHER PTHR10972 UniProtKB/TrEMBL
Pfam Oxysterol_BP UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PhenoGen Osbpl8 PhenoGen
PROSITE OSBP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP SSF144000 UniProtKB/TrEMBL
UniProt A0A0G2JXN8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZMZ6_RAT UniProtKB/TrEMBL
  A0A8I6A2N1_RAT UniProtKB/TrEMBL
  A0A8I6ADC9_RAT UniProtKB/TrEMBL
  A0A8I6GDH8 ENTREZGENE, UniProtKB/TrEMBL
  B5DF26_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Osbpl8  oxysterol binding protein-like 8  RGD1561474  similar to oxysterol-binding protein-like protein 8 isoform a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561474  similar to oxysterol-binding protein-like protein 8 isoform a   RGD1561474_predicted  similar to oxysterol-binding protein-like protein 8 isoform a (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561474_predicted  similar to oxysterol-binding protein-like protein 8 isoform a (predicted)  LOC314824  similar to oxysterol-binding protein-like protein 8 isoform a  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC314824  similar to oxysterol-binding protein-like protein 8 isoform a      Symbol and Name status set to provisional 70820 PROVISIONAL