 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations |
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Analyze GeneStrainQTL List |
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Gene Annotator (Annotation Comparison) |
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GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | RGD automated data pipeline |
| 3. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Osbpl8 (Rattus norvegicus - Norway rat) |
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| OSBPL8 (Homo sapiens - human) |
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| Osbpl8 (Mus musculus - house mouse) |
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| Osbpl8 (Chinchilla lanigera - long-tailed chinchilla) |
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| OSBPL8 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| OSBPL8 (Canis lupus familiaris - dog) |
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| Osbpl8 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| OSBPL8 (Sus scrofa - pig) |
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| OSBPL8 (Chlorocebus sabaeus - African green monkey) |
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| Osbpl8 (Heterocephalus glaber - naked mole-rat) |
No map positions available. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Position Markers| D7Rat147 |
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| D7Uwm11 |
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| RH130422 |
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| BF405318 |
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| AU047198 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 40 | 30 | 14 | 19 | 14 | 3 | 3 | 74 | 35 | 41 | 11 | 3 | |
| Low | 3 | 3 | 27 | 27 | 27 | 5 | 7 | 5 | |||||
| Below cutoff | 1 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001309455 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006241324 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006241325 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006241326 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594846 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594847 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07057079 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07057080 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07057081 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07073301 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01049173 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01049174 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01049175 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01049176 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC168899 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473960 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000058589 ⟹ ENSRNOP00000055387 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | ENSRNOT00000091910 ⟹ ENSRNOP00000070347 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001309455 ⟹ NP_001296384 | ||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
GTCCCAGCGGACACTAGGGCCCCGGATTCCGGCGTCACTGTGATCCCGTTGAAGCCTGCTGCCThide sequence |
| RefSeq Acc Id: | XM_006241324 ⟹ XP_006241386 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
GGTTTCCACACTTCTAGGATGGCTAAACACTAATGGAAGGAAGAGCATAAGCCCACCATCCATThide sequence |
| RefSeq Acc Id: | XM_006241325 ⟹ XP_006241387 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
GGTTTCCACACTTCTAGGATGGCTAAACACTAATGGAAGGAAGAGCATAAGCCCACCATCCATThide sequence |
| RefSeq Acc Id: | XM_006241326 ⟹ XP_006241388 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
GGTTTCCACACTTCTAGGATGGCTAAACACTAATGGAAGGAAGAGCATAAGCCCACCATCCATThide sequence |
| RefSeq Acc Id: | XM_017594846 ⟹ XP_017450335 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
ACTGTGTTTTTAATGCTTTTTTTTTCCTTAAGAAGAAATACTCTTAAGGTTATATGGAATGATGhide sequence |
| RefSeq Acc Id: | XM_017594847 ⟹ XP_017450336 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
TTTGTAAACTCTGGGTGTTCTTTAATTTCAGACCTCAGGAATTTGAGATAAAATTGCTCCTGAGhide sequence |
Protein Sequences| Protein RefSeqs | NP_001296384 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006241386 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006241387 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006241388 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017450335 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017450336 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAI68899 | (Get FASTA) | NCBI Sequence Viewer |
| EDM16737 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM16738 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM16739 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM16740 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | XP_006241387 ⟸ XM_006241325 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MSQRQGKDAYPTPTRELQPSLSPASLHSQGFERGKEDISQNKDDSSLSMSKSKSESKLYNGSEKhide sequence |
| RefSeq Acc Id: | XP_006241386 ⟸ XM_006241324 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MLLGDSKDVLGPSTVVANSEEPQHLTPGKMSQRQGKDAYPTPTRELQPSLSPASLHSQGFERGKhide sequence |
| RefSeq Acc Id: | XP_006241388 ⟸ XM_006241326 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MSQRQGKDAYPTPTRELQPSLSPASLHSQGFERGKEDISQNKDDSSLSMSKSKSESKLYNGSEKhide sequence |
| RefSeq Acc Id: | NP_001296384 ⟸ NM_001309455 |
| - UniProtKB: | A0A0G2JXN8 (UniProtKB/TrEMBL) |
| - Sequence: |
MEAGLADGGPDRCSLLGDSKDVLGPSTVVANSEEPQHLTPGKMSQRQGKDAYPTPTRELQPSLShide sequence |
| RefSeq Acc Id: | XP_017450336 ⟸ XM_017594847 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MSQRQGKDAYPTPTRELQPSLSPASLHSQGFERGKEDISQNKDDSSLSMSKSKSESKLYNGSEKhide sequence |
| RefSeq Acc Id: | XP_017450335 ⟸ XM_017594846 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MKEESSQHRRFSSCTGVSSVLFPPRIDGRKLVRNASFGGYNELSPSLQGFERGKEDISQNKDDShide sequence |
| RefSeq Acc Id: | ENSRNOP00000055387 ⟸ ENSRNOT00000058589 |
| RefSeq Acc Id: | ENSRNOP00000070347 ⟸ ENSRNOT00000091910 |
Protein Domains
PH
TranscriptomePromoters| RGD ID: | 13695196 | ||||||||
| Promoter ID: | EPDNEW_R5713 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Osbpl8_1 | ||||||||
| Description: | oxysterol binding protein-like 8 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1561474 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000026962 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000055387 | UniProtKB/TrEMBL |
| ENSRNOP00000070347 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000058589 | UniProtKB/TrEMBL |
| ENSRNOT00000091910 | ENTREZGENE, UniProtKB/TrEMBL | |
| Gene3D-CATH | 2.30.29.30 | UniProtKB/TrEMBL |
| InterPro | OSBP_sf | UniProtKB/TrEMBL |
| Oxysterol-bd | UniProtKB/TrEMBL | |
| Oxysterol-bd_CS | UniProtKB/TrEMBL | |
| PH/PTB_dom | UniProtKB/TrEMBL | |
| PH_domain | UniProtKB/TrEMBL | |
| KEGG Report | rno:314824 | UniProtKB/TrEMBL |
| NCBI Gene | 314824 | ENTREZGENE |
| PANTHER | PTHR10972 | UniProtKB/TrEMBL |
| Pfam | Oxysterol_BP | UniProtKB/TrEMBL |
| PF00169 | UniProtKB/TrEMBL | |
| PhenoGen | Osbpl8 | PhenoGen |
| PROSITE | OSBP | UniProtKB/TrEMBL |
| PH_DOMAIN | UniProtKB/TrEMBL | |
| SMART | SM00233 | UniProtKB/TrEMBL |
| Superfamily-SCOP | SSF144000 | UniProtKB/TrEMBL |
| UniGene | Rn.229943 | ENTREZGENE |
| UniProt | A0A0G2JXN8 | ENTREZGENE, UniProtKB/TrEMBL |
| B5DF26_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2010-05-05 | Osbpl8 | oxysterol binding protein-like 8 | RGD1561474 | similar to oxysterol-binding protein-like protein 8 isoform a | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-04-30 | RGD1561474 | similar to oxysterol-binding protein-like protein 8 isoform a | RGD1561474_predicted | similar to oxysterol-binding protein-like protein 8 isoform a (predicted) | 'predicted' is removed | 2292626 | APPROVED |
| 2006-03-07 | RGD1561474_predicted | similar to oxysterol-binding protein-like protein 8 isoform a (predicted) | LOC314824 | similar to oxysterol-binding protein-like protein 8 isoform a | Symbol and Name status set to approved | 1299863 | APPROVED |
| 2006-02-09 | LOC314824 | similar to oxysterol-binding protein-like protein 8 isoform a | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
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| More on Osbpl8 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1561474 |
| Created: | 2006-02-09 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
