Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nr2c1 | Rat | endometriosis | | ISO | NR2C1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:22138541 | |
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nr2c1 | Rat | endometriosis | | ISO | NR2C1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:22138541 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Mouse Genome Database (MGD) | Mouse Genome Database (MGD) |
3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:7794280 | PMID:8858600 | PMID:9071982 | PMID:9369481 | PMID:9774688 | PMID:9795341 | PMID:11463856 | PMID:12477932 | PMID:16130175 | PMID:17974920 | PMID:18682553 |
Nr2c1 (Rattus norvegicus - Norway rat) |
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NR2C1 (Homo sapiens - human) |
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Nr2c1 (Mus musculus - house mouse) |
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Nr2c1 (Chinchilla lanigera - long-tailed chinchilla) |
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NR2C1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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NR2C1 (Canis lupus familiaris - dog) |
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Nr2c1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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NR2C1 (Sus scrofa - pig) |
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NR2C1 (Chlorocebus sabaeus - green monkey) |
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Nr2c1 (Heterocephalus glaber - naked mole-rat) |
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Variants in Nr2c1
331 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_145780 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_017594671 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594672 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039078458 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039078459 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_005486547 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC105868 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BC061822 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473960 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
DQ515798 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ228928 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
L26398 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000009578 ⟹ ENSRNOP00000009578 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000089228 ⟹ ENSRNOP00000071901 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_145780 ⟹ NP_665723 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017594671 ⟹ XP_017450160 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039078458 ⟹ XP_038934386 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039078459 ⟹ XP_038934387 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XR_005486547 | ||||||||||||
Type: | NON-CODING | ||||||||||||
Position: |
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Protein RefSeqs | NP_665723 | (Get FASTA) | NCBI Sequence Viewer |
XP_017450160 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038934386 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038934387 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH61822 | (Get FASTA) | NCBI Sequence Viewer |
AAL31316 | (Get FASTA) | NCBI Sequence Viewer | |
ABF70961 | (Get FASTA) | NCBI Sequence Viewer | |
EDM16889 | (Get FASTA) | NCBI Sequence Viewer | |
EDM16890 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000009578.1 | ||
ENSRNOP00000071901.2 | |||
ENSRNOP00055007494 | |||
ENSRNOP00060006182 | |||
ENSRNOP00065015404 | |||
GenBank Protein | Q8VIJ4 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_665723 ⟸ NM_145780 |
- UniProtKB: | Q8VIJ4 (UniProtKB/Swiss-Prot), A0A8L2R4T2 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017450160 ⟸ XM_017594671 |
- Peptide Label: | isoform X1 |
- UniProtKB: | Q8VIJ4 (UniProtKB/Swiss-Prot), A0A8L2R4T2 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000071901 ⟸ ENSRNOT00000089228 |
Ensembl Acc Id: | ENSRNOP00000009578 ⟸ ENSRNOT00000009578 |
RefSeq Acc Id: | XP_038934386 ⟸ XM_039078458 |
- Peptide Label: | isoform X1 |
- UniProtKB: | Q8VIJ4 (UniProtKB/Swiss-Prot), A0A8L2R4T2 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038934387 ⟸ XM_039078459 |
- Peptide Label: | isoform X1 |
- UniProtKB: | Q8VIJ4 (UniProtKB/Swiss-Prot), A0A8L2R4T2 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q8VIJ4-F1-model_v2 | AlphaFold | Q8VIJ4 | 1-590 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13695154 | ||||||||
Promoter ID: | EPDNEW_R5678 | ||||||||
Type: | initiation region | ||||||||
Name: | Nr2c1_1 | ||||||||
Description: | nuclear receptor subfamily 2, group C, member 1 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:3200 | AgrOrtholog |
BioCyc Gene | G2FUF-34372 | BioCyc |
Ensembl Genes | ENSRNOG00000006983 | Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ENSRNOG00055005975 | UniProtKB/Swiss-Prot | |
ENSRNOG00060004922 | UniProtKB/Swiss-Prot | |
ENSRNOG00065012332 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000009578.5 | UniProtKB/Swiss-Prot |
ENSRNOT00000089228.2 | UniProtKB/TrEMBL | |
ENSRNOT00055009689 | UniProtKB/Swiss-Prot | |
ENSRNOT00060008220 | UniProtKB/Swiss-Prot | |
ENSRNOT00065020082 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 1.10.565.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
3.30.50.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:5599041 | IMAGE-MGC_LOAD |
InterPro | NHR-like_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
NR2C1/2-like_DBD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
NR2C1/2-like_LBD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Nucl_hrmn_rcpt_lig-bd | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Nuclear_hormone_rcpt_NR2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Nuclear_hrmn_rcpt | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Znf_hrmn_rcpt | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Znf_NHR/GATA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:252924 | UniProtKB/Swiss-Prot |
MGC_CLONE | MGC:72289 | IMAGE-MGC_LOAD |
NCBI Gene | Nr2c1 | ENTREZGENE |
PANTHER | NUCLEAR HORMONE RECEPTOR | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Hormone_recep | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
zf-C4 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Nr2c1 | PhenoGen |
PRINTS | STRDHORMONER | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
STROIDFINGER | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PROSITE | NR_LBD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
NUCLEAR_REC_DBD_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
NUCLEAR_REC_DBD_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000006983 | RatGTEx |
ENSRNOG00055005975 | RatGTEx | |
ENSRNOG00060004922 | RatGTEx | |
ENSRNOG00065012332 | RatGTEx | |
SMART | HOLI | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ZnF_C4 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | Glucocorticoid receptor-like (DNA-binding domain) | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF48508 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A8L2R4T2 | ENTREZGENE, UniProtKB/TrEMBL |
A6IG09_RAT | UniProtKB/TrEMBL | |
NR2C1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2008-05-06 | Nr2c1 | nuclear receptor subfamily 2, group C, member 1 | Psg4 | pregnancy specific beta-1-glycoprotein 4 | Data merged from RGD:628790 | 737654 | APPROVED |
2003-02-27 | Psg4 | pregnancy specific beta-1-glycoprotein 4 | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2001-06-20 | Tr2 | Orphan receptor, TR2-11 | Symbol withdrawn, duplicate of Nr2c1 (RGD:3200) | 67952 | WITHDRAWN | ||
2001-06-20 | Nr2c1 | Nuclear receptor subfamily 2, group C, member 1 | Name updated | 67952 | APPROVED |
Note Type | Note | Reference |
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gene_homology | mouse Nr2c1 exhibits transcription factor, subtilase, ligand-dependent nuclear receptor and steroid hormone activities | 704405 |