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Gene: Nr2c1 (nuclear receptor subfamily 2, group C, member 1) Mus musculus
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Symbol: Nr2c1
Name: nuclear receptor subfamily 2, group C, member 1
RGD ID: 731685
Description: Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein homodimerization activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of retinoic acid receptor signaling pathway. Localizes to PML body. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; jaw; and sensory organ. Orthologous to human NR2C1 (nuclear receptor subfamily 2 group C member 1); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4831444H07Rik; 80-3 cNDA; 80.3; early embryonic nuclear receptor; Ee; Eenr; mTR2; nuclear receptor subfamily 2 group C member 1; nuclear receptor subfamily 2, group H, member 1; orphan nuclear receptor TR2; orphan receptor, TR2-11; testicular receptor 2; TR; TR2; Tr2-1; Tr2-11
Orthologs:
Homo sapiens (human) : NR2C1 (nuclear receptor subfamily 2 group C member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nr2c1 (nuclear receptor subfamily 2, group C, member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr2c1 (nuclear receptor subfamily 2 group C member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR2C1 (nuclear receptor subfamily 2 group C member 1)
Canis lupus familiaris (dog) : NR2C1 (nuclear receptor subfamily 2 group C member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr2c1 (nuclear receptor subfamily 2 group C member 1)
Sus scrofa (pig) : NR2C1 (nuclear receptor subfamily 2 group C member 1)
Chlorocebus sabaeus (African green monkey) : NR2C1 (nuclear receptor subfamily 2 group C member 1)
Heterocephalus glaber (naked mole-rat) : Nr2c1 (nuclear receptor subfamily 2 group C member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391093,983,491 - 94,033,078 (+)NCBI
GRCm381094,147,542 - 94,197,216 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1094,148,023 - 94,197,211 (+)EnsemblGRCm38mm10GRCm38
MGSCv371093,610,676 - 93,659,959 (+)NCBIGRCm37mm9NCBIm37
MGSCv361093,586,085 - 93,625,150 (+)NCBImm8
Celera1096,123,279 - 96,172,755 (+)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1048.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nr2c1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731685
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-11-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.