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Gene: Cbarp (CACN subunit beta associated regulatory protein) Rattus norvegicus

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Symbol:

Cbarp

Name:

CACN subunit beta associated regulatory protein

RGD ID:

1307185

Description:

Predicted to enable transmembrane transporter binding activity. Involved in negative regulation of voltage-gated calcium channel activity. Located in secretory granule. Orthologous to human CBARP (CACN subunit beta associated regulatory protein); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CACN beta subunit associated regulatory protein; calcium channel, voltage-dependent, beta subunit associated regulatory protein; Dos; downstream of Stk11; LOC314622; MGC189449

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,217,314 - 10,225,855 (+)	NCBI		GRCr8
mRatBN7.2	7	9,566,637 - 9,575,204 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,566,364 - 9,575,204 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	12,449,657 - 12,458,156 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,324,996 - 14,333,495 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,186,091 - 12,194,592 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,433,422 - 12,441,048 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,433,933 - 12,441,048 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,603,527 - 12,611,153 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	11,079,431 - 11,087,057 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	11,079,064 - 11,086,662 (+)	NCBI
Celera	7	7,743,241 - 7,750,842 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cerebral creatine deficiency syndrome (ISO)

cyclic hematopoiesis (ISO)

Peutz-Jeghers syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

coumarin (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dicrotophos (ISO)

dioxygen (EXP)

endosulfan (EXP)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

indometacin (ISO)

L-methionine (ISO)

Licochalcone B (ISO)

manganese(II) chloride (EXP)

N-nitrosodiethylamine (ISO)

O-methyleugenol (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

piperonyl butoxide (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

Triptolide (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of calcium ion transmembrane transport (ISO)

negative regulation of calcium ion-dependent exocytosis (IBA,ISO)

negative regulation of voltage-gated calcium channel activity (IMP,ISO)

Cellular Component

growth cone (ISO)

plasma membrane (IBA,ISO)

secretory granule (IDA,ISO)

Molecular Function

protein binding (ISO)

transmembrane transporter binding (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	BARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosis.	Beguin P, etal., J Cell Biol. 2014 Apr 28;205(2):233-49. doi: 10.1083/jcb.201304101. Epub 2014 Apr 21.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Cbarp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,217,314 - 10,225,855 (+)	NCBI		GRCr8
mRatBN7.2	7	9,566,637 - 9,575,204 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,566,364 - 9,575,204 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	12,449,657 - 12,458,156 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,324,996 - 14,333,495 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,186,091 - 12,194,592 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,433,422 - 12,441,048 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,433,933 - 12,441,048 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,603,527 - 12,611,153 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	11,079,431 - 11,087,057 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	11,079,064 - 11,086,662 (+)	NCBI
Celera	7	7,743,241 - 7,750,842 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

CBARP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	1,228,287 - 1,238,502 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	1,228,287 - 1,238,027 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	1,228,286 - 1,238,004 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	1,180,947 - 1,188,990 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	1,180,954 - 1,188,841	NCBI
Celera	19	1,164,180 - 1,172,223 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	1,005,343 - 1,039,838 (-)	NCBI		HuRef
CHM1_1	19	1,229,860 - 1,237,926 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	1,196,845 - 1,207,060 (-)	NCBI		T2T-CHM13v2.0

Cbarp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	79,966,268 - 79,976,189 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	79,966,285 - 79,976,669 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	80,130,434 - 80,140,355 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	80,130,451 - 80,140,835 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	79,593,179 - 79,598,128 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	79,593,179 - 79,598,128 (-)	NCBI		MGSCv36	mm8
Celera	10	81,145,266 - 81,150,215 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Cbarp
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	6,671,726 - 6,677,205 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	6,671,719 - 6,678,338 (+)	NCBI	ChiLan1.0	ChiLan1.0

CBARP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	5,570,337 - 5,580,431 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	4,807,138 - 4,817,065 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	19	1,212,854 - 1,220,108 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	1,212,854 - 1,220,104 (-)	Ensembl	panpan1.1		panPan2

CBARP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	57,554,162 - 57,559,126 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	57,554,032 - 57,559,612 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	57,352,590 - 57,361,543 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	58,292,499 - 58,301,436 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	58,294,280 - 58,301,173 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	57,348,311 - 57,356,988 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	57,827,591 - 57,836,230 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	58,030,594 - 58,039,504 (+)	NCBI		UU_Cfam_GSD_1.0

Cbarp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	217,216,615 - 217,233,911 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	601,521 - 607,175 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	601,108 - 607,823 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CBARP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	77,220,972 - 77,230,058 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	77,220,790 - 77,230,418 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa11.1	2	77,228,094 - 77,230,411 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	77,823,483 - 77,831,001 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103233598
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	999,327 - 1,006,632 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666081	7,857,295 - 7,864,976 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cbarp
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	7,437,564 - 7,443,353 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	7,435,633 - 7,444,483 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cbarp
19 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	184
Count of miRNA genes:	142
Interacting mature miRNAs:	151
Transcripts:	ENSRNOT00000060690
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	44782185	Rat
1300176	Hrtrt10	Heart rate QTL 10	3.19		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	664270	26029351	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	5329019	50329019	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1	44822433	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
10755438	Coatc9	Coat color QTL 9		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	3529280	48529280	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	31962314	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	9462246	58265113	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	7573985	52573985	Rat
2317047	Wbc4	White blood cell count QTL 4		0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	7	1	35342956	Rat
10755440	Coatc10	Coat color QTL 10		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	7496499	52496499	Rat
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	27829089	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	34000259	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	31962314	Rat

Markers in Region

D7Got1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	9,565,207 - 9,565,291 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	12,431,409 - 12,431,492	NCBI	Rnor6.0
Rnor_5.0	7	12,601,514 - 12,601,597	UniSTS	Rnor5.0
RGSC_v3.4	7	11,077,417 - 11,077,501	RGD	RGSC3.4
RGSC_v3.4	7	11,077,418 - 11,077,501	UniSTS	RGSC3.4
RGSC_v3.1	7	11,077,418 - 11,077,501	RGD
Celera	7	7,741,231 - 7,741,314	UniSTS
RH 3.4 Map	7	34.6	UniSTS
RH 3.4 Map	7	34.6	RGD
RH 2.0 Map	7	0.0	RGD
Cytogenetic Map	7	q11	UniSTS

Stk11

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	9,568,257 - 9,568,385 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	12,434,458 - 12,434,585	NCBI	Rnor6.0
Rnor_5.0	7	12,604,563 - 12,604,690	UniSTS	Rnor5.0
RGSC_v3.4	7	11,080,467 - 11,080,594	UniSTS	RGSC3.4
Celera	7	7,744,256 - 7,744,383	UniSTS
Cytogenetic Map	7	q11	UniSTS

BE110397

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	9,568,464 - 9,568,619 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	12,434,665 - 12,434,819	NCBI	Rnor6.0
Rnor_5.0	7	12,604,770 - 12,604,924	UniSTS	Rnor5.0
RGSC_v3.4	7	11,080,674 - 11,080,828	UniSTS	RGSC3.4
Celera	7	7,744,463 - 7,744,617	UniSTS
RH 3.4 Map	7	41.1	UniSTS
Cytogenetic Map	7	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	90	89	58	25	58	6	217	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001388507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC169056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000060690 ⟹ ENSRNOP00000057421

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	9,566,364 - 9,575,204 (+)	Ensembl
Rnor_6.0 Ensembl	7	12,433,933 - 12,441,048 (+)	Ensembl

RefSeq Acc Id:

NM_001108070 ⟹ NP_001101540

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,218,169 - 10,225,855 (+)	NCBI
mRatBN7.2	7	9,567,515 - 9,575,204 (+)	NCBI
Rnor_6.0	7	12,433,422 - 12,441,048 (+)	NCBI
Rnor_5.0	7	12,603,527 - 12,611,153 (+)	NCBI
RGSC_v3.4	7	11,079,431 - 11,087,057 (+)	RGD
Celera	7	7,743,241 - 7,750,842 (+)	RGD

Sequence:

show sequence

CGAGCCTGGCATCGGGTTCTCTGCGCTTTCCCTCACCGTATCCTGCTTGGGGGGGAGGGGGTCC
TGGTGGACGTTCTGTGGGGACTCCATGTCTAGGCTCCCATTCTCGCTGGTCCTCATGATCCCGC
CTTCCTCGCCTTGGGTCTCCAGCCATCTTCCTTCCCACCTCTCATTACCATCCTCACCGAGCCC
CACCCCCCTCCAGCCTGAACTCATTTTCCGACCTACATATGCACCCCTTATCACCCACCAAGAC
TGATGCCCGTTGTCTCTGCCTCGGAGCGCTGAGGAGACGTAGCCTTCTTGGGGATACATTCGTT
TATTCAAGTCCCCCCACACAACTCCAATACCATCCAGTCTAAGAAATACTGGTGACGTTGGAGC
CTGTGGGCTCTTCTTCCATGGGAAACTGTTATCTCGTTTTAGAGTCAAGACACGGTACTCGGAA
CAGTCGATCTAGGCGGACGCGACGTCCAACCAACGCTGGCGCGGGGTTATTTTAACAGTCCCTT
TCTGAATCCACCCCACCTCTTGATGTGCCCTAGCCTCAGTTTCTCCACTCGTCTGGCAGAGACC
TGCCTCAAAATGCAGCCCACGGCCACCATGGCCACAGCGGCCGCCACTACTGCCACGGTTGCCC
TGACGACTTCGTGGGACAATGCCACCAACCGCCCCACGGCGGAGCCTGACCCCATCTTGGACAA
CTATGTGCTGCTGGTGGTGGTGATGTCGCTGTTCGTTGGAGGCACGCTGGTGGTGCTGTCTGGC
GTTCTTCTGCTCTGCAAACGCTGCTGGGAGGTGCACCAGCGCTTCAACAGGGCCATGGAAGAAA
CAGAAAAGACCACCACTACCTACCTGGACAACGGCACCCACCCCATACAAGACTGGGCGCAGTT
CGAGTCCGACTCATCTCTGTTTCCTTAACGCCCAGGCGTAGACCCCGACTGCAGGGGGGAAGAC
CCCGAGGGCCAGGACACCGAAACAGAGCGCTTCCTAGCCACCACCTCCACCGGTCGCCGCGTGT
CCTTCAACGAGGCTGCCCTGTTTGAACAGAGCCGCAAGGCTCAGGACAAGGGCCGCCGGTACAC
CCTGACAGAAGGGGATTTCCATCACCTCAAGAATGCCCGCCTCACCCACCTCCACCTACCGCCT
CTCAAAATCGCTACCATCCATGAGTGTGACTCGGGTGAGGCCAGTGCTGCGGCCACGCCCCACC
CCCACCCGGCTTCCACCCCCAAGGACAGCTTGGCTATATTCCAGCCCCCTGGGAAGTCCCTCAC
TGGCCACTCGGTGGGCCCCAGCTCTGCCCTCCCAGGTGATCCCTACAGCTCCGTGGACTTCTCG
GAGATCAGCCCCTCGGCCTCCAGTGACTCTGGGGAGGGCACCTCGTTAGATGCGGGTACCCGGG
GTACCAAGGCTGCTGGGCCCGAGACAGCACCTGGGGAGATGGGCACAGGCTCCTCCGGGGCTGG
CACTGTTTTGCAATTCTTCACTCGGCTACGCCGCCATGCCAGCCTGGATGGAGCCAGCCCCTAC
TTCAAGGTCAAGAAATGGAAGTTGGAGTCCAGCCAGAGAGCGTCCAGTCTGGACACGAGAGGTT
CCCCGAAGCGGCACCACTTTCAGCGACAGCGGGCAGCCAGCGAGAGCATGGAGCAGGAGGGGGA
TATCCCCCATGCTGACTTCATTCAATACATTGCCAGCGCAGGCGACTCGGTGGCCTTCCCACCC
CCCCGCCCCTTTCTGGCCAGCCCCACCAGCCCGCCCCCCACTCTCGGCAGGCTAGAGGCAGCTG
AGGCGGCGGGAGGAGGAAGCCCCGAGACTCCTCCGGAGCATGGCATCAGTTTGGGGCCCGAGCA
TGCGCAGCAGCAGGACCCGCAGCAAGAGCAGGACGCCGAGCATGCACAGTGCAGCTACCGTGAT
CTGTGGAGCCTTCGTGCTTCGCTCGAGCTCCACGCAGCCACTGCATCAGACCACAGCAGTAGCG
GCAATGACCGTGACTCAGTGCGCAGCGGCGATAGCTCGGGCTCCGGTTCCGGGGGTGGAGGCGC
AGCACCCGCCTTCCCGCCCCCTCCTGAGTCTCCGCCTGCCTTGCGGCCTAAGGACGGCGAAGCC
CGACGCCTGTTACAGATGGACAGTGGCTACGCGAGCATCGAGGGACGTGGAGCTGGCGATGAAG
TTTCTGAACTTCCTGCTCCAGCTCGGAGCCCTCCCCGCAGCCCGCGAGCCTGGCCACGCAGGCC
GCGCCGCGATTATAGCATCGATGAGAAGACGGACGCTCTTTTCCATGAATTCCTGCGCCACGAT
CCTCATTTTGATGATGCTCCAAGACACCGCGCACGTGCGCATCCTCACACTCATGCGCGGAAGC
AATGGCAACAGAGAGGCCGGCAGCACAGCGACCCCGGAGGTGCACGCGTGGCCACGCCCCCTGG
GGCTACCCGCCCCACACGTGCCCCCTTACGCCGTGGGGATAGTGTTGATTGTCCTCCTGAAGGC
CGTGCGCCGCCCATCACCGGTGATGACCCATCCATTCCCGTCATTGAGGAGGAGCCTGGTGGTG
GAGGCAGTGGTTGCCCAGGCTCTGGGTTATGTGTTGAGCCCGCCGGGGCACTGCTGGACAAACT
AGCAGCTAGCCTCGACGAGAGACTCTTCTCTCCCCGTCTTGCTGAGCCAGTTGCCTCATCCCCG
GTGCTGATTGTCGCTGCTGCCGCCCCTACATCCCCTGACCACAGCCCAGCCTAAGCTCTGTGTA
CTGGACCTGCCTCTCGGCTGCTTTGCCGGCGGCACGTGGGGCCGCTGTGGGAATGGTGGCGACA
GCGGGAGCAACCTGAGGTTGCTGTGCATGGGTACGCGGCCCAAATCCCAAGTGTGTACAAGGAG
TGTCCCCTCGGGCACTTAGCAGGGTGCAGTGGGCCTCCGGATGCACAAGGCCTCCGGACCCAGG
CTCAGCTGCAGGGAGGATGAAGATCTTGGATTCTCAAGTCCATATACGGTTGACCCCCGGCACC
CAGCCTCTGGCCACAGATGCGGGTGGAGCAGGTTCTGAGGTGCGCGTGCAGCCTCCCTCCAGGA
TCAGCCGAACCTCCACACTCGTGAGCACGTGCTGGCAGTGCCACTGCATGCGTGAACCTACTGG
A

hide sequence

RefSeq Acc Id:

NM_001388507 ⟹ NP_001375436

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,217,353 - 10,225,855 (+)	NCBI
mRatBN7.2	7	9,566,699 - 9,575,204 (+)	NCBI

RefSeq Acc Id:

XM_039078983 ⟹ XP_038934911

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,218,308 - 10,225,855 (+)	NCBI
mRatBN7.2	7	9,566,960 - 9,575,204 (+)	NCBI

RefSeq Acc Id:

XM_039078984 ⟹ XP_038934912

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,217,314 - 10,225,855 (+)	NCBI
mRatBN7.2	7	9,566,637 - 9,575,204 (+)	NCBI

RefSeq Acc Id:

XM_039078985 ⟹ XP_038934913

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,218,308 - 10,224,280 (+)	NCBI
mRatBN7.2	7	9,566,960 - 9,573,625 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101540	(Get FASTA)	NCBI Sequence Viewer
	NP_001375436	(Get FASTA)	NCBI Sequence Viewer
	XP_038934911	(Get FASTA)	NCBI Sequence Viewer
	XP_038934912	(Get FASTA)	NCBI Sequence Viewer
	XP_038934913	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI69056	(Get FASTA)	NCBI Sequence Viewer
	EDL89327	(Get FASTA)	NCBI Sequence Viewer
	EDL89328	(Get FASTA)	NCBI Sequence Viewer
	EDL89329	(Get FASTA)	NCBI Sequence Viewer
	EDL89330	(Get FASTA)	NCBI Sequence Viewer
	EDL89331	(Get FASTA)	NCBI Sequence Viewer
	EDL89332	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000057421.4

RefSeq Acc Id:

NP_001101540 ⟸ NM_001108070

- UniProtKB:

A6K8Q7 (UniProtKB/TrEMBL), B5DFH0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGTGSSGAGTVLQFFTRLRRHASLDGASPYFKVKKWKLESSQRASSLDTRGSPKRHHFQRQRAA
SESMEQEGDIPHADFIQYIASAGDSVAFPPPRPFLASPTSPPPTLGRLEAAEAAGGGSPETPPE
HGISLGPEHAQQQDPQQEQDAEHAQCSYRDLWSLRASLELHAATASDHSSSGNDRDSVRSGDSS
GSGSGGGGAAPAFPPPPESPPALRPKDGEARRLLQMDSGYASIEGRGAGDEVSELPAPARSPPR
SPRAWPRRPRRDYSIDEKTDALFHEFLRHDPHFDDAPRHRARAHPHTHARKQWQQRGRQHSDPG
GARVATPPGATRPTRAPLRRGDSVDCPPEGRAPPITGDDPSIPVIEEEPGGGGSGCPGSGLCVE
PAGALLDKLAASLDERLFSPRLAEPVASSPVLIVAAAAPTSPDHSPA

hide sequence

Ensembl Acc Id:

ENSRNOP00000057421 ⟸ ENSRNOT00000060690

RefSeq Acc Id:	XP_038934912 ⟸ XM_039078984
- Peptide Label:	isoform X2
- UniProtKB:	F1MAS1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001375436 ⟸ NM_001388507
- UniProtKB:	A6K8Q7 (UniProtKB/TrEMBL), B5DFH0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934911 ⟸ XM_039078983
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038934913 ⟸ XM_039078985
- Peptide Label:	isoform X3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1MAS1-F1-model_v2	AlphaFold	F1MAS1	1-431	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307185	AgrOrtholog
BioCyc Gene	G2FUF-34917	BioCyc
Ensembl Genes	ENSRNOG00000024349	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000060690.5	UniProtKB/TrEMBL
InterPro	CBARP	UniProtKB/TrEMBL
KEGG Report	rno:314622	UniProtKB/TrEMBL
NCBI Gene	314622	ENTREZGENE
PANTHER	PTHR28597	UniProtKB/TrEMBL
	VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT-ASSOCIATED REGULATORY PROTEIN	UniProtKB/TrEMBL
PhenoGen	Cbarp	PhenoGen
RatGTEx	ENSRNOG00000024349	RatGTEx
UniProt	A6K8Q7	ENTREZGENE, UniProtKB/TrEMBL
	B5DFH0	ENTREZGENE, UniProtKB/TrEMBL
	F1MAS1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-03	Cbarp	CACN subunit beta associated regulatory protein	Cbarp	CACN beta subunit associated regulatory protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-11	Cbarp	CACN beta subunit associated regulatory protein	Cbarp	calcium channel, voltage-dependent, beta subunit associated regulatory protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-07-22	Cbarp	calcium channel, voltage-dependent, beta subunit associated regulatory protein	Dos	downstream of Stk11	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Dos	downstream of Stk11	Dos_predicted	downstream of Stk11 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Dos_predicted	downstream of Stk11 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar