Mapk15 (mitogen-activated protein kinase 15)

Advanced Search (OLGA)

Gene: Mapk15 (mitogen-activated protein kinase 15) Rattus norvegicus

Analyze

Symbol:

Mapk15

Name:

mitogen-activated protein kinase 15

RGD ID:

628675

Description:

Predicted to enable MAP kinase activity and chromatin binding activity. Involved in negative regulation of nucleobase-containing compound metabolic process; positive regulation of protein metabolic process; and response to estradiol. Located in nucleus. Orthologous to human MAPK15 (mitogen-activated protein kinase 15); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ERK-7; ERK-8; Erk7; extracellular signal-regulated kinase 7; extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MAPK15 (mitogen-activated protein kinase 15)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Mapk15 (mitogen-activated protein kinase 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mapk15 (mitogen-activated protein kinase 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MAPK15 (mitogen-activated protein kinase 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MAPK15 (mitogen-activated protein kinase 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mapk15 (mitogen-activated protein kinase 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MAPK15 (mitogen-activated protein kinase 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MAPK15 (mitogen-activated protein kinase 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mapk15 (mitogen-activated protein kinase 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Mapk15 (mitogen-activated protein kinase 15)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MAPK15 (mitogen-activated protein kinase 15)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mapk15 (mitogen-activated protein kinase 15)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mapk-15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Erk7	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mapk15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Candidate Gene For:

Eau6

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	109,575,619 - 109,595,339 (+)	NCBI		GRCr8
mRatBN7.2	7	107,694,907 - 107,714,640 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	107,694,964 - 107,714,645 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	109,448,581 - 109,453,894 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	111,672,256 - 111,677,569 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	111,618,237 - 111,623,549 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	117,041,287 - 117,061,799 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	117,055,395 - 117,061,047 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	117,027,214 - 117,046,813 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	114,026,694 - 114,032,007 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	114,060,919 - 114,066,236 (+)	NCBI
Celera	7	104,066,261 - 104,071,573 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast cancer (ISO)

Brown-Vialetto-Van Laere syndrome 2 (ISO)

epidermolysis bullosa simplex with muscular dystrophy (ISO)

Experimental Neoplasms (ISO)

holoprosencephaly (ISO)

urinary bladder cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

actinomycin D (ISO)

ammonium chloride (EXP)

arsane (EXP,ISO)

arsenic atom (EXP,ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

caffeine (EXP)

capsaicin (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

copper atom (ISO)

copper(0) (ISO)

Cuprizon (EXP)

decabromodiphenyl ether (EXP)

dimethylarsinic acid (ISO)

folic acid (ISO)

furan (EXP)

glycidol (EXP)

L-methionine (ISO)

lead diacetate (EXP)

lipopolysaccharide (ISO)

maneb (ISO)

methoxyacetic acid (EXP)

methylarsonic acid (ISO)

methylmercury chloride (EXP)

Monobutylphthalate (EXP)

N-methyl-4-phenylpyridinium (ISO)

Nutlin-3 (ISO)

ochratoxin A (EXP)

organoselenium compound (ISO)

paraquat (ISO)

pentachlorophenol (ISO)

phenobarbital (ISO)

pyridaben (ISO)

resveratrol (ISO)

sinapic acid (EXP)

sodium arsenate (ISO)

sodium arsenite (EXP,ISO)

triptonide (ISO)

valproic acid (ISO)

zingerone (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (IEA,ISO)

dopamine uptake (IEA,ISO,ISS)

endoplasmic reticulum organization (IEA,ISO,ISS)

intracellular signal transduction (IBA)

MAPK cascade (IEA)

negative regulation of cell migration (IEA,ISO,ISS)

negative regulation of DNA replication (IMP)

negative regulation of transcription by RNA polymerase II (IMP)

positive regulation of cell population proliferation (IEA,ISO,ISS)

positive regulation of metaphase/anaphase transition of meiosis I (IEA,ISO)

positive regulation of protein catabolic process (IMP)

positive regulation of protein phosphorylation (IMP)

positive regulation of protein ubiquitination (IMP)

positive regulation of spindle assembly (IEA,ISO)

positive regulation of telomere maintenance (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

protein autophosphorylation (IEA,IMP,ISO,ISS)

protein localization to ciliary transition zone (IEA,ISO)

protein phosphorylation (IDA,IEA)

regulation of autophagy (IEA,ISO,ISS)

regulation of cilium assembly (IEA,ISO,ISS)

regulation of COPII vesicle coating (IEA,ISO,ISS)

response to estradiol (IMP)

Cellular Component

autophagosome (IEA,ISO,ISS)

axoneme (ISO)

bicellular tight junction (IEA)

cell-cell junction (IEA,ISO,ISS)

centriole (IEA,ISO,ISS)

ciliary basal body (IEA,ISO,ISS)

cytoplasm (IBA,ISO,ISS)

cytoplasmic vesicle (IEA)

Golgi apparatus (IEA,ISO,ISS)

meiotic spindle (IEA,ISO)

nucleus (IBA,IDA,IEA,ISO)

Molecular Function

ATP binding (IEA)

chromatin binding (IEA,ISO,ISS)

kinase activity (ISO,ISS)

MAP kinase activity (IEA,ISO,ISS)

protein binding (IPI,ISO)

protein kinase activity (ISO,ISS)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	ERK7 is an autoactivated member of the MAPK family.	Abe MK, etal., J Biol Chem. 2001 Jun 15;276(24):21272-9. Epub 2001 Apr 3.
2.	Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth.	Abe MK, etal., Mol Cell Biol 1999 Feb;19(2):1301-12.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Extracellular signal-regulated kinase 7, a regulator of hormone-dependent estrogen receptor destruction.	Henrich LM, etal., Mol Cell Biol. 2003 Sep;23(17):5979-88.
5.	Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel.	Qian Z, etal., J Biol Chem. 1999 Jan 15;274(3):1621-7.
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11875070	PMID:12477932	PMID:15033983	PMID:19166846	PMID:20638370	PMID:20733054	PMID:21190936	PMID:21531765	PMID:21847093	PMID:22948227	PMID:23351492	PMID:24618899
PMID:25823377	PMID:26595526	PMID:28842414	PMID:29021280

Genomics

Comparative Map Data

Mapk15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	109,575,619 - 109,595,339 (+)	NCBI		GRCr8
mRatBN7.2	7	107,694,907 - 107,714,640 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	107,694,964 - 107,714,645 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	109,448,581 - 109,453,894 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	111,672,256 - 111,677,569 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	111,618,237 - 111,623,549 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	117,041,287 - 117,061,799 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	117,055,395 - 117,061,047 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	117,027,214 - 117,046,813 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	114,026,694 - 114,032,007 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	114,060,919 - 114,066,236 (+)	NCBI
Celera	7	104,066,261 - 104,071,573 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

MAPK15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	143,716,349 - 143,722,458 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	143,716,340 - 143,722,458 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	144,798,519 - 144,804,628 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	144,870,495 - 144,876,621 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	141,109,455 - 141,115,595 (+)	NCBI		Celera
Cytogenetic Map	8	q24.3	NCBI
HuRef	8	140,051,333 - 140,057,442 (+)	NCBI		HuRef
CHM1_1	8	144,838,551 - 144,844,676 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	144,872,787 - 144,878,895 (+)	NCBI		T2T-CHM13v2.0

Mapk15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	75,865,581 - 75,871,002 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	75,865,618 - 75,871,003 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	75,993,732 - 75,999,153 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	75,993,769 - 75,999,154 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	75,824,199 - 75,829,583 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	75,821,024 - 75,826,408 (+)	NCBI		MGSCv36	mm8
Celera	15	77,494,814 - 77,500,199 (+)	NCBI		Celera
Cytogenetic Map	15	D3	NCBI
cM Map	15	35.2	NCBI

Mapk15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	2,413,822 - 2,419,276 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955454	2,413,393 - 2,420,703 (+)	NCBI	ChiLan1.0	ChiLan1.0

MAPK15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	161,198,908 - 161,205,165 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	136,716,178 - 136,722,428 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	140,468,365 - 140,474,604 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	143,482,245 - 143,488,498 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	143,481,567 - 143,492,859 (+)	Ensembl	panpan1.1		panPan2

MAPK15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	37,317,061 - 37,322,792 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	37,316,424 - 37,322,792 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	37,273,594 - 37,279,329 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	37,789,031 - 37,794,766 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	37,789,106 - 37,794,731 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	37,463,171 - 37,468,902 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	37,580,097 - 37,585,790 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	38,061,417 - 38,067,119 (+)	NCBI		UU_Cfam_GSD_1.0

Mapk15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	994,469 - 1,000,806 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	8,420,732 - 8,425,884 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	8,420,850 - 8,425,996 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAPK15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	909,268 - 915,475 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	909,266 - 915,537 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MAPK15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	137,932,291 - 137,938,392 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	137,932,364 - 137,938,626 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	1,942,955 - 1,949,042 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mapk15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	13,047,125 - 13,056,308 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624735	13,049,509 - 13,077,509 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mapk15
109 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	152
Count of miRNA genes:	109
Interacting mature miRNAs:	116
Transcripts:	ENSRNOT00000012461
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	80221299	124373579	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	102297359	133492884	Rat
2298475	Eau6	Experimental allergic uveoretinitis QTL 6		0.0029	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	7	84257275	129257275	Rat
71114	Niddm14	Non-insulin dependent diabetes mellitus QTL 14	4.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	84257275	129257275	Rat
1357336	Gluco6	Glucose level QTL 6	3.4		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	7	94811326	116294265	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	43747012	108555253	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	69736356	112729554	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	91412594	129807172	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	103146217	116738842	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	73829340	130221005	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	83153392	128153392	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	90482196	135012528	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	81737938	126737938	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	80221299	109401111	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	96670164	135012528	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
2306821	Bp335	Blood pressure QTL 335		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	106571501	135012528	Rat
1558655	Swd4	Spike wave discharge measurement QTL 4	3.68	0.0002	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge severity grade (CMO:0001988)	7	86983365	131983365	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	80221299	125221299	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	94811085	116738842	Rat
731174	Uae23	Urinary albumin excretion QTL 23	2.4	0.0042	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	7	104603555	135012528	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	68938720	113886318	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	80221299	112308525	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	68938720	113886318	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	91281130	135012528	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	68938720	113886318	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	69736226	117455174	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	4	22	107	79	84	53	23	53	6	166	56	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_173331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC126537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF078798	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC091172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000012461 ⟹ ENSRNOP00000012460

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	107,709,305 - 107,714,639 (+)	Ensembl
Rnor_6.0 Ensembl	7	117,055,623 - 117,060,957 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000091960 ⟹ ENSRNOP00000075332

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	107,694,964 - 107,714,645 (+)	Ensembl
Rnor_6.0 Ensembl	7	117,055,395 - 117,061,047 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110168 ⟹ ENSRNOP00000085833

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	107,709,305 - 107,714,639 (+)	Ensembl

RefSeq Acc Id:

NM_173331 ⟹ NP_775453

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,590,026 - 109,595,339 (+)	NCBI
mRatBN7.2	7	107,709,327 - 107,714,640 (+)	NCBI
Rnor_6.0	7	117,055,645 - 117,060,958 (+)	NCBI
Rnor_5.0	7	117,027,214 - 117,046,813 (+)	NCBI
RGSC_v3.4	7	114,026,694 - 114,032,007 (+)	RGD
Celera	7	104,066,261 - 104,071,573 (+)	RGD

Sequence:

show sequence

AAAGAATCGGTGGACAAAGAGCCAGCGTCTGCCTCTCACCATGTGTGCTGCCGAGGTGGACCGT
CATGTATCCCAGAGATACCTGATCAAGCGGAGGCTTGGGAAGGGGGCCTACGGCATTGTATGGA
AGGCCATGGACCGGAGGACTGGTGAGGTAGTGGCCATCAAGAAAATCTTTGATGCCTTTAGGGA
CCAGACAGATGCTCAGAGGACCTTCCGTGAAATCATGCTTCTCCGGGAGTTTGGGGGCCATCCC
AACATCATCCGCCTGCTTGATGTAATCCCAGCAAAGAATGACAGGGATATTTACCTGGTGTTTG
AGTCCATGGACACCGACCTGAACGCGGTCATCCAGAAGGGCAGACTGTTGGAGGACATCCACAA
ACGTTGCATCTTTTACCAGCTCCTGAGAGCCACCAAGTTTATCCATTCAGGGCGCGTCATTCAC
CGGGACCAGAAGCCAGCCAACGTTCTATTGGATGCTGCTTGCCGGGTGAAACTATGTGACTTTG
GCCTGGCACGCTCCCTCAGTGACTTCCCTGAAGGGCCTGGGGGCCAGGCCCTGACAGAATATGT
GGCCACACGCTGGTACCGAGCTCCAGAGGTGCTTCTGTCTTCCCGATGGTATACCCCTGGGGTG
GACATGTGGAGCCTGGGCTGCATACTGGGAGAGATGCTTCGAGGGCAGCCACTGTTTCCGGGTA
CATCTACTTTCCACCAGCTGGAGCTGATCCTGGAGACCATTCCATTGCCCTCCATGGAGGAGCT
CCAGGGCCTTGGATCAGACTACAGTGCTTTGATTCTGCAGAATCTTGGATCCAGGCCACGGCAG
ACGCTGGACGCCCTCCTGCCGCCAGACACCCCCCCAGAAGCCCTGGACCTCCTCAAGCGACTCT
TGGCATTTGCTCCGGACAAACGGCTTAGTGCAGAGCAGGCTCTTCAACACCCTTACGTGCAGAG
ATTCCATTGCCCCGACCGCGAGTGGACACGGGGGTCCGATGTGCGGCTCCCGGTACACGAAGGA
GACCAGCTCTCTGCACCAGAGTATCGCAACCGCCTGTACCAGATGATCCTGGAGCGGAGACGGA
ACAGCCGCAGCCCTCGAGAGGAAGACTTGGGGGTTGTGGCCTCGCGGGCAGAGCTCAGGGCTTC
CCAGAGGCAATCGCTCAAGCCCGGAGTCCTCCCCCAGGTCTTGGCGGAGACGCCTGCGCGGAAA
CGCGGACCCAAACCTCAGAATGGCCATGGTCACGATCCCGAGCATGTGGAAGTTCGCAGGCAGA
GTTCAGACCCCCTGTACCAACTTCCGCCGCCAGGCAGCGGGGAAAGGCCCCCAGGGGCCACAGG
GGAGCCACCCTCCGCACCCTCAGGGGTGAAGACTCACGTTAGGGCGGTGGCGCCCTCCCTGACT
TCACAGGCCGCGGCTCAGGCGGCCAATCAGCCTCTGATCCGCAGTGATCCGGCCCGGGGCGGTG
GGCCAAGGGCTGTCGGCGCGCGACGGGTCCCTTCCCGCCTGCCCCGGGAGGCCCCGGAACCCCG
ACCCGGCCGAAGGATGTTTGGCATCTCGGTCTCGCAGGGGGCCCAGGGTGCAGCCAGAGCTGCT
CTTGGCGGCTACTCCCAGGCCTACGGGACCGTGTGCCGCTCCGCGCTGGGCCGCCTGCCTCTGC
TCCCCGGACCGCGTGCGTGAGCCGCCCACCAACCTCCTTGCGGCAAACTGGCGCCGGCCCCCAG
ACCCCAGCGCATCATCTCCCTTCTCTGCCTCCCCGCCTTCGAGTTCCAGGAGGGTTCTCTGAGC
CTCTCTCCCCTAAGGGGGAGTAGATGGAGGTTTCCACTCCACCCCCAACAATTTATTCCAATAA
AGTTTTATCTTTCTTAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006241779 ⟹ XP_006241841

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,575,619 - 109,595,339 (+)	NCBI
mRatBN7.2	7	107,694,907 - 107,714,640 (+)	NCBI
Rnor_6.0	7	117,041,287 - 117,060,958 (+)	NCBI
Rnor_5.0	7	117,027,214 - 117,046,813 (+)	NCBI

Sequence:

show sequence

TGTTCAGGAACGCATTGCTCTGCAGCACCTCGTCTATCCGCTGCTCACAGACCGCCAGGCTCTC
CGAGAGCATCGCATACTCGCGCTGTGTTGGGATCCCCAGAACTGGAGTCACAGAAAATTGTAAC
TGAGCACCCATACAGTCACCAGGAGGAATTGAACCTGGATCCTGCAGAAGAGCAGTCAGTACAA
CTGAGCAACCTCTCCAGCCTCAAGAAACTCTCTTCAAAAGCTGTAGCACAGGCTTCGTTCCTGA
GAGAGCCTGGCTCTGATTTCCCGATACTCAGCACCCTCTTGTGCCCTGAGATGTGCACAACTCA
GGGGCTAGCAGAGCTGCCTCCCCACCTCAACCTCCACCCAGCGTGCAGCACTGACCAGGAAAAA
CAAGTGGACAGGTGGGGCTAGCTGCAGACCCCGCCCATTGGCGCAGGCGCAAGGGAGGAGCACC
GCGACTGCCGGTTCCCAAGCCAACGGATCAACAGGTCCAGCTCCAAGGAAAGAATCGGTGGACA
AAGAGCCAGCGTCTGCCTCTCACCATGTGTGCTGCCGAGGTGGACCGTCATGTATCCCAGAGAT
ACCTGATCAAGCGGAGGCTTGGGAAGGGGGCCTACGGCATTGTATGGAAGGCCATGGACCGGAG
GACTGGTGAGGTAGTGGCCATCAAGAAAATCTTTGATGCCTTTAGGGACCAGACAGATGCTCAG
AGGACCTTCCGTGAAATCATGCTTCTCCGGGAGTTTGGGGGCCATCCCAACATCATCCGCCTGC
TTGATGTAATCCCAGCAAAGAATGACAGGGATATTTACCTGGTGTTTGAGTCCATGGACACCGA
CCTGAACGCGGTCATCCAGAAGGGCAGACTGTTGGAGGACATCCACAAACGTTGCATCTTTTAC
CAGCTCCTGAGAGCCACCAAGTTTATCCATTCAGGGCGCGTCATTCACCGGGACCAGAAGCCAG
CCAACGTTCTATTGGATGCTGCTTGCCGGGTGAAACTATGTGACTTTGGCCTGGCACGCTCCCT
CAGTGACTTCCCTGAAGGGCCTGGGGGCCAGGCCCTGACAGAATATGTGGCCACACGCTGGTAC
CGAGCTCCAGAGGTGCTTCTGTCTTCCCGATGGTATACCCCTGGGGTGGACATGTGGAGCCTGG
GCTGCATACTGGGAGAGATGCTTCGAGGGCAGCCACTGTTTCCGGGTACATCTACTTTCCACCA
GCTGGAGCTGATCCTGGAGACCATTCCATTGCCCTCCATGGAGGAGCTCCAGGGCCTTGGATCA
GACTACAGTGCTTTGATTCTGCAGAATCTTGGATCCAGGCCACGGCAGACGCTGGACGCCCTCC
TGCCGCCAGACACCCCCCCAGAAGCCCTGGACCTCCTCAAGCGACTCTTGGCATTTGCTCCGGA
CAAACGGCTTAGTGCAGAGCAGGCTCTTCAACACCCTTACGTGCAGAGATTCCATTGCCCCGAC
CGCGAGTGGACACGGGGGTCCGATGTGCGGCTCCCGGTACACGAAGGAGACCAGCTCTCTGCAC
CAGAGTATCGCAACCGCCTGTACCAGATGATCCTGGAGCGGAGACGGAACAGCCGCAGCCCTCG
AGAGGAAGACTTGGGGGTTGTGGCCTCGCGGGCAGAGCTCAGGGCTTCCCAGAGGCAATCGCTC
AAGCCCGGAGTCCTCCCCCAGGTCTTGGCGGAGACGCCTGCGCGGAAACGCGGACCCAAACCTC
AGAATGGCCATGGTCACGATCCCGAGCATGTGGAAGTTCGCAGGCAGAGTTCAGACCCCCTGTA
CCAACTTCCGCCGCCAGGCAGCGGGGAAAGGCCCCCAGGGGCCACAGGGGAGCCACCCTCCGCA
CCCTCAGGGGTGAAGACTCACGTTAGGGCGGTGGCGCCCTCCCTGACTTCACAGGCCGCGGCTC
AGGCGGCCAATCAGCCTCTGATCCGCAGTGATCCGGCCCGGGGCGGTGGGCCAAGGGCTGTCGG
CGCGCGACGGGTCCCTTCCCGCCTGCCCCGGGAGGCCCCGGAACCCCGACCCGGCCGAAGGATG
TTTGGCATCTCGGTCTCGCAGGGGGCCCAGGGTGCAGCCAGAGCTGCTCTTGGCGGCTACTCCC
AGGCCTACGGGACCGTGTGCCGCTCCGCGCTGGGCCGCCTGCCTCTGCTCCCCGGACCGCGTGC
GTGAGCCGCCCACCAACCTCCTTGCGGCAAACTGGCGCCGGCCCCCAGACCCCAGCGCATCATC
TCCCTTCTCTGCCTCCCCGCCTTCGAGTTCCAGGAGGGTTCTCTGAGCCTCTCTCCCCTAAGGG
GGAGTAGATGGAGGTTTCCACTCCACCCCCAACAATTTATTCCAATAAAGTTTTATCTTTCTTA

hide sequence

RefSeq Acc Id:

XM_039078534 ⟹ XP_038934462

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,575,619 - 109,595,339 (+)	NCBI
mRatBN7.2	7	107,694,907 - 107,714,640 (+)	NCBI

RefSeq Acc Id:

XM_039078535 ⟹ XP_038934463

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,575,619 - 109,595,339 (+)	NCBI
mRatBN7.2	7	107,694,907 - 107,714,171 (+)	NCBI

RefSeq Acc Id:

XM_039078537 ⟹ XP_038934465

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,575,619 - 109,594,118 (+)	NCBI
mRatBN7.2	7	107,694,907 - 107,713,419 (+)	NCBI

RefSeq Acc Id:

XM_039078538 ⟹ XP_038934466

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,575,619 - 109,594,118 (+)	NCBI
mRatBN7.2	7	107,694,907 - 107,713,419 (+)	NCBI

RefSeq Acc Id:

XM_063263083 ⟹ XP_063119153

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,575,619 - 109,595,339 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_775453	(Get FASTA)	NCBI Sequence Viewer
	XP_006241841	(Get FASTA)	NCBI Sequence Viewer
	XP_038934462	(Get FASTA)	NCBI Sequence Viewer
	XP_038934463	(Get FASTA)	NCBI Sequence Viewer
	XP_038934465	(Get FASTA)	NCBI Sequence Viewer
	XP_038934466	(Get FASTA)	NCBI Sequence Viewer
	XP_063119153	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD12719	(Get FASTA)	NCBI Sequence Viewer
	EDM16025	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000012460.3
	ENSRNOP00000075332.1
	ENSRNOP00000085833.1
	ENSRNOP00060030033
	ENSRNOP00065011266
GenBank Protein	Q9Z2A6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_775453 ⟸ NM_173331

- UniProtKB:

Q9Z2A6 (UniProtKB/Swiss-Prot), A6HS47 (UniProtKB/TrEMBL), A0A8I6A4Q6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MCAAEVDRHVSQRYLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIML
LREFGGHPNIIRLLDVIPAKNDRDIYLVFESMDTDLNAVIQKGRLLEDIHKRCIFYQLLRATKF
IHSGRVIHRDQKPANVLLDAACRVKLCDFGLARSLSDFPEGPGGQALTEYVATRWYRAPEVLLS
SRWYTPGVDMWSLGCILGEMLRGQPLFPGTSTFHQLELILETIPLPSMEELQGLGSDYSALILQ
NLGSRPRQTLDALLPPDTPPEALDLLKRLLAFAPDKRLSAEQALQHPYVQRFHCPDREWTRGSD
VRLPVHEGDQLSAPEYRNRLYQMILERRRNSRSPREEDLGVVASRAELRASQRQSLKPGVLPQV
LAETPARKRGPKPQNGHGHDPEHVEVRRQSSDPLYQLPPPGSGERPPGATGEPPSAPSGVKTHV
RAVAPSLTSQAAAQAANQPLIRSDPARGGGPRAVGARRVPSRLPREAPEPRPGRRMFGISVSQG
AQGAARAALGGYSQAYGTVCRSALGRLPLLPGPRA

hide sequence

RefSeq Acc Id:	XP_006241841 ⟸ XM_006241779
- Peptide Label:	isoform X2
- UniProtKB:	Q9Z2A6 (UniProtKB/Swiss-Prot), A6HS47 (UniProtKB/TrEMBL), A0A8I6A4Q6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCAAEVDRHVSQRYLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIML LREFGGHPNIIRLLDVIPAKNDRDIYLVFESMDTDLNAVIQKGRLLEDIHKRCIFYQLLRATKF IHSGRVIHRDQKPANVLLDAACRVKLCDFGLARSLSDFPEGPGGQALTEYVATRWYRAPEVLLS SRWYTPGVDMWSLGCILGEMLRGQPLFPGTSTFHQLELILETIPLPSMEELQGLGSDYSALILQ NLGSRPRQTLDALLPPDTPPEALDLLKRLLAFAPDKRLSAEQALQHPYVQRFHCPDREWTRGSD VRLPVHEGDQLSAPEYRNRLYQMILERRRNSRSPREEDLGVVASRAELRASQRQSLKPGVLPQV LAETPARKRGPKPQNGHGHDPEHVEVRRQSSDPLYQLPPPGSGERPPGATGEPPSAPSGVKTHV RAVAPSLTSQAAAQAANQPLIRSDPARGGGPRAVGARRVPSRLPREAPEPRPGRRMFGISVSQG AQGAARAALGGYSQAYGTVCRSALGRLPLLPGPRA hide sequence

Ensembl Acc Id:

ENSRNOP00000012460 ⟸ ENSRNOT00000012461

Ensembl Acc Id:

ENSRNOP00000075332 ⟸ ENSRNOT00000091960

RefSeq Acc Id:	XP_038934462 ⟸ XM_039078534
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6A4Q6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934463 ⟸ XM_039078535
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038934465 ⟸ XM_039078537
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038934466 ⟸ XM_039078538
- Peptide Label:	isoform X6

Ensembl Acc Id:

ENSRNOP00000085833 ⟸ ENSRNOT00000110168

RefSeq Acc Id:	XP_063119153 ⟸ XM_063263083
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2KAB2 (UniProtKB/TrEMBL)

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9Z2A6-F1-model_v2	AlphaFold	Q9Z2A6	1-547	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628675	AgrOrtholog
BioCyc Gene	G2FUF-32965	BioCyc
Ensembl Genes	ENSRNOG00000009336	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00060021050	UniProtKB/Swiss-Prot
	ENSRNOG00065009415	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000012461.5	UniProtKB/Swiss-Prot
	ENSRNOT00000091960.2	UniProtKB/TrEMBL
	ENSRNOT00000110168.1	UniProtKB/TrEMBL
	ENSRNOT00060036494	UniProtKB/Swiss-Prot
	ENSRNOT00065015061	UniProtKB/Swiss-Prot
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MAP_kinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MAP_kinase_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:286997	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	286997	ENTREZGENE
PANTHER	MITOGEN-ACTIVATED PROTEIN KINASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MITOGEN-ACTIVATED PROTEIN KINASE 15	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mapk15	PhenoGen
PROSITE	MAPK	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000009336	RatGTEx
	ENSRNOG00060021050	RatGTEx
	ENSRNOG00065009415	RatGTEx
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2KAB2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A4Q6	ENTREZGENE, UniProtKB/TrEMBL
	A6HS47	ENTREZGENE, UniProtKB/TrEMBL
	MK15_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Mapk15	mitogen-activated protein kinase 15	Erk7	extracellular signal-regulated kinase 7	Symbol and Name updated	1299863	APPROVED
2003-02-27	Erk7	extracellular signal-regulated kinase 7			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a TEY activation motif and a C-terminal domain which inhibits its growth and nuclear localization	632686
gene_product	member of the mAP kinase family	632686
gene_protein	61 kDa in size	632686

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD