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Gene: Tbxa2r (thromboxane A2 receptor) Rattus norvegicus
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Symbol: Tbxa2r
Name: thromboxane A2 receptor
Description: Exhibits thromboxane receptor activity. Involved in several processes, including cellular response to lipopolysaccharide; positive regulation of vasoconstriction; and response to testosterone. Localizes to the acrosomal vesicle and plasma membrane. Used to study adult respiratory distress syndrome; kidney failure; thrombocytopenia; and toxic shock syndrome. Human ortholog(s) of this gene implicated in asthma and blood platelet disease. Orthologous to human TBXA2R (thromboxane A2 receptor); PARTICIPATES IN eicosanoid signaling pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH (R)-noradrenaline; (RS)-amphetamine; (S)-nicotine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: prostanoid TP receptor; Thromboxane receptor; TXA2-R; TXR2
Orthologs:
Homo sapiens (human) : TBXA2R (thromboxane A2 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Tbxa2r (thromboxane A2 receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbxa2r (thromboxane A2 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : TBXA2R (thromboxane A2 receptor)
Canis lupus familiaris (dog) : TBXA2R (thromboxane A2 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbxa2r (thromboxane A2 receptor)
Sus scrofa (pig) : TBXA2R (thromboxane A2 receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0711,253,153 - 11,259,233 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0711,419,887 - 11,425,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,867,739 - 9,872,536 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.179,867,738 - 9,872,536 (-)NCBI
Celera76,572,330 - 6,577,127 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tbxa2r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3825
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.