Strain Report - Rat Genome Database

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Strain: LEW/NIcoCrlf

Symbol: LEW/NIcoCrlf
Strain: LEW
Substrain: NIcoCrlf
RGD ID: 634363
Citation ID: RRID:RGD_634363
Ontology ID: RS:0000523
Also Known As: LEW/CRLIFO; LEW/NIco
Type: inbred
Available Source: Charles River, France
Description: A substrain of LEW that was purchased from Charles River France and bred at Institut Francois Magendie, Bordeaux Cedax, France.
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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Clinical Measurement
systolic blood pressure

References

References - curated
# Reference Title Reference Citation
1. A genetic and multifactorial analysis of anxiety-related behaviours in Lewis and SHR intercrosses. Ramos A, etal., Behav Brain Res. 1998 Nov;96(1-2):195-205.
2. Identification of female-specific QTLs affecting an emotionality-related behavior in rats. Ramos A, etal., Mol Psychiatry 1999 Sep;4(5):453-62.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines
4. Evidence for a female-specific effect of a chromosome 4 locus on anxiety-related behaviors and ethanol drinking in rats. Vendruscolo LF, etal., Genes Brain Behav. 2006 Aug;5(6):441-50.
5. Genetic influences on behavioral and neuroendocrine responses to predator-odor stress in rats. Vendruscolo LF, etal., Neurosci Lett. 2006 Dec 1;409(2):89-94. Epub 2006 Oct 18.

Region

Strain QTL Data
Symbol Name Trait
Anxrr16 Anxiety related response QTL 16 locomotor behavior trait   (VT:0001392)    
Anxrr17 Anxiety related response QTL 17 locomotor behavior trait   (VT:0001392)    
Bp141 Blood pressure QTL 141 arterial blood pressure trait   (VT:2000000)    
Bp142 Blood pressure QTL 142 arterial blood pressure trait   (VT:2000000)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_behavior Differs from SHR/Bord in anxiety-related dimensions. Displays contracting response in the elevated plus-maze, the open field and the black/white box. 631324