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Gene: Sox10 (SRY-box transcription factor 10) Rattus norvegicus
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Symbol: Sox10
Name: SRY-box transcription factor 10
Description: Exhibits several functions, including DNA-binding transcription factor activity; promoter-specific chromatin binding activity; and transcription factor binding activity. Involved in several processes, including cellular response to progesterone stimulus; regulation of nervous system development; and regulation of transcription, DNA-templated. Localizes to the cytoplasm and nucleus. Colocalizes with the chromatin. Human ortholog(s) of this gene implicated in Kallmann syndrome; PCWH syndrome; Waardenburg syndrome type 2E; and Waardenburg syndrome type 4C. Orthologous to human SOX10 (SRY-box 10); INTERACTS WITH 2-trans,6-trans,10-trans-geranylgeranyl diphosphate; 5alpha-pregnane-3,20-dione; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: SRY (sex determining region Y)-box 10; SRY box 10; SRY-box containing gene 10; transcription factor SOX-10
Orthologs:
Homo sapiens (human) : SOX10 (SRY-box transcription factor 10)  HGNC  Alliance
Mus musculus (house mouse) : Sox10 (SRY (sex determining region Y)-box 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox10 (SRY-box transcription factor 10)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX10 (SRY-box transcription factor 10)
Canis lupus familiaris (dog) : SOX10 (SRY-box transcription factor 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox10 (SRY-box transcription factor 10)
Sus scrofa (pig) : SOX10 (SRY-box transcription factor 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07120,393,238 - 120,403,523 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07120,387,071 - 120,397,340 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,138,694 - 117,149,939 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17117,172,923 - 117,184,169 (-)NCBI
Celera7107,059,767 - 107,070,023 (-)NCBICelera
Cytogenetic Map7q34NCBI
RH 3.4 Map7839.3RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sox10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3735
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.