Iddm34 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Iddm34 (Insulin dependent diabetes mellitus QTL 34) Rattus norvegicus

Symbol: Iddm34
Name: Insulin dependent diabetes mellitus QTL 34
RGD ID: 2299163
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: age at onset/diagnosis of type 1 diabetes mellitus   (CMO:0001140)    
LOD Score: 2.71
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr87116,269,196 - 132,020,414RGD_MAPPER_PIPELINE
mRatBN7.2791,281,130 - 135,012,528RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.07100,028,953 - 145,729,302RGD_MAPPER_PIPELINERnor6.0
Rnor_5.07100,609,080 - 143,501,887RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4796,517,746 - 137,757,704RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: ACI.BBDP-(RT1u)(Gimap5)/Sunn BBDP/WorSunn 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Iddm34Rattype 1 diabetes mellitus  IDA 2303106 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Iddm34Ratincreased circulating glucose level  IDA 2303106 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Iddm34Ratage at onset/diagnosis of type 1 diabetes mellitus  IDA 2303106 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Iddm34Ratspecific pathogen-free condition  IDA 2303106 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Iddm34Ratblood glucose analysis  IDA 2303106 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Iddm34RatACI.BBDP-(RT1u)(Gimap5)/Sunn  IEA 2303106 RGD 
Iddm34RatBBDP/WorSunn  IEA 2303106 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Iddm34Ratblood glucose amount  IDA 2303106 RGD 


#
Reference Title
Reference Citation
1. Unpublished observations for Iddm QTL Personal communication with Dr. Wallis
2. TYPE 1 DIABETES IN THE BB RAT: A POLYGENIC DISEASE. Wallis RH, etal., Diabetes. 2009 Apr;58(4):1007-17. Epub 2009 Jan 23


1 to 20 of 865 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41063713LOC120093663uncharacterized LOC12009366379124652491351728Rat
41035867LOC120094053U6 spliceosomal RNA79137067191370777Rat
40934539LOC120093664uncharacterized LOC12009366479142761691449462Rat
41108340Pgam1-ps4phosphoglycerate mutase 1, pseudogene 479148702691487671Rat
15649014933412E24RiklRIKEN cDNA 4933412E24 gene like79161629791618030Rat
41393725LOC120093914U6 spliceosomal RNA79169334391693442Rat
7750896LOC102552490uncharacterized LOC10255249079171694691768010Rat
7665134LOC102552316uncharacterized LOC10255231679174741291753435Rat
1563100Gpd1l2glycerol-3-phosphate dehydrogenase 1 like 279194025891942125Rat
41261377LOC120094056U6 spliceosomal RNA79206798292068087Rat
41222771LOC120093879keratin-associated protein 5-3-like79208875792089368Rat
41311443LOC120093988small nucleolar RNA SNORA1779227354192273672Rat
1564515A1bgl1alpha-1-B glycoprotein like 179231493092318652Rat
1562236Lratd2LRAT domain containing 279237671392387045Rat
7637212Ghitm-ps1growth hormone inducible transmembrane protein, pseudogene 179245969592460814Rat
69417A1bgalpha-1-B glycoprotein79249393492498460Rat
41157576LOC120093667uncharacterized LOC12009366779261620892664552Rat
41366091LOC120093668uncharacterized LOC12009366879286029092892964Rat
41070538LOC120093670uncharacterized LOC12009367079299943793076507Rat
9295089LOC103692925uncharacterized LOC10369292579303137893285485Rat

1 to 20 of 865 rows
1 to 20 of 1181 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10252D7Mit121367114727471114727581Ratregion
10253D7Wox201447114727449114727593Ratregion
10427D7Wox192577106839225106839474Ratregion
10431D7Wox182507106741074106741295Ratregion
10431D7Wox182507106773255106773476Ratregion
10447D7Wox212717113938271113938544Ratregion
10448D7Mgh32447113915925113916171Ratregion
10449D7Mit161627113886156113886318Ratregion
10472D7Wox301987114321734114321932Ratregion
10514D7Wox231157131786627131786744Ratregion
10515D7Mit262157131786600131786815Ratregion
10935D7Wox1413179359564793595780Ratregion
10936D7Arb520479359562793595833Ratregion
10937D7Wox1515979359562093595781Ratregion
10938D7Wox2911979359563393595754Ratregion
10939D7Mit2721079359563193595843Ratregion
11165D7Mit92767130221005130221281Ratregion
33798D7Mit242537121668493121668746Ratregion
33816D7Mit11947116738749116738842Ratregion
33838D3Mit181887116932605116932728Ratregion
1 to 20 of 1181 rows

Flank 1: (D7Rat21)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2791,281,130 - 91,281,285 (+)MAPPER
Rnor_6.07100,028,953 - 100,029,107NCBI
Rnor_5.07100,609,080 - 100,609,234UniSTS
RGSC_v3.4796,517,746 - 96,517,901RGD
RGSC_v3.4796,517,747 - 96,517,901UniSTS
RGSC_v3.1796,551,976 - 96,552,131RGD
Celera788,041,825 - 88,041,979UniSTS
SHRSP x BN Map752.31UniSTS
SHRSP x BN Map752.31RGD
Peak: (D7Wox48)
Rat AssemblyChrPosition (strand)Source
GRCr87124,144,703 - 124,144,907 (+)Marker Load Pipeline
mRatBN7.27122,265,140 - 122,265,344 (+)MAPPER
Rnor_6.07132,296,671 - 132,296,874NCBI
Rnor_5.07131,970,582 - 131,970,785UniSTS
RGSC_v3.47129,544,865 - 129,545,068UniSTS
Celera7118,715,727 - 118,715,930UniSTS
Cytogenetic Map7q35UniSTS
Flank 2: (D7Rat2)
Rat AssemblyChrPosition (strand)Source
GRCr87132,020,162 - 132,020,414 (+)Marker Load Pipeline
RGSC_v3.47137,757,333 - 137,757,704RGD
RGSC_v3.17137,833,770 - 137,834,141RGD
RH 3.4 Map71075.7RGD
RH 3.4 Map71075.7UniSTS
RH 2.0 Map7784.8RGD
SHRSP x BN Map786.2099RGD
FHH x ACI Map771.29RGD
Cytogenetic Map7 RGD


1 to 10 of 63 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat

1 to 10 of 63 rows


Note Type Note Reference
qtl_general software used: R/QTL and QTL Cartographer 2303106
qtl_general number of animals used: 574 animals which were negative for glycosuria until 165 days 2303106