Tmbim6 (transmembrane BAX inhibitor motif containing 6) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Tmbim6 (transmembrane BAX inhibitor motif containing 6) Rattus norvegicus
Analyze
Symbol: Tmbim6
Name: transmembrane BAX inhibitor motif containing 6
RGD ID: 3842
Description: Predicted to have endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in lung development and spermatogenesis. Predicted to localize to endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of invasive ductal carcinoma. Orthologous to human TMBIM6 (transmembrane BAX inhibitor motif containing 6); INTERACTS WITH acrylamide; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ab1-011; Ac1-149; bax inhibitor 1; Bax inhibitor-1; BI-1; Cc1-27; Tegt; testis enhanced gene transcript; testis-enhanced gene transcript protein; transmembrane BAX inhibitor motif-containing protein 6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27130,512,428 - 130,543,637 (+)NCBI
Rnor_6.0 Ensembl7141,034,982 - 141,069,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07141,039,433 - 141,070,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X115,557,801 - 115,572,802 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,139,438 - 138,154,243 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17138,216,492 - 138,230,680 (+)NCBI
Celera7127,009,876 - 127,024,679 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:9660918   PMID:12477932   PMID:15304216   PMID:15489334   PMID:16757804   PMID:19328063   PMID:19946888   PMID:21068390   PMID:21075086   PMID:22240901   PMID:26582200   PMID:29169414  


Genomics

Comparative Map Data
Tmbim6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27130,512,428 - 130,543,637 (+)NCBI
Rnor_6.0 Ensembl7141,034,982 - 141,069,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07141,039,433 - 141,070,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X115,557,801 - 115,572,802 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,139,438 - 138,154,243 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17138,216,492 - 138,230,680 (+)NCBI
Celera7127,009,876 - 127,024,679 (+)NCBICelera
Cytogenetic Map7q36NCBI
TMBIM6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1249,707,725 - 49,764,934 (+)EnsemblGRCh38hg38GRCh38
GRCh381249,741,557 - 49,764,934 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371250,135,340 - 50,158,717 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,421,560 - 48,444,984 (+)NCBINCBI36hg18NCBI36
Build 341248,432,511 - 48,444,760NCBI
Celera1248,931,228 - 48,954,652 (+)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1247,166,860 - 47,190,297 (+)NCBIHuRef
CHM1_11250,101,626 - 50,125,066 (+)NCBICHM1_1
Tmbim6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,290,828 - 99,307,930 (+)NCBIGRCm39mm39
GRCm39 Ensembl1599,290,763 - 99,307,930 (+)Ensembl
GRCm381599,392,947 - 99,410,049 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,392,882 - 99,410,049 (+)EnsemblGRCm38mm10GRCm38
MGSCv371599,223,378 - 99,240,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361599,221,020 - 99,238,074 (+)NCBImm8
Celera15101,548,094 - 101,565,263 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Tmbim6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547335,275 - 358,503 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955547335,344 - 358,503 (+)NCBIChiLan1.0ChiLan1.0
TMBIM6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11239,879,951 - 39,902,607 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,879,951 - 39,902,303 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01238,986,844 - 39,010,307 (-)NCBIMhudiblu_PPA_v0panPan3
TMBIM6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,921,606 - 4,944,830 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,921,606 - 4,944,783 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,313,127 - 41,336,268 (+)NCBI
ROS_Cfam_1.0274,971,016 - 4,994,198 (-)NCBI
UMICH_Zoey_3.1274,936,445 - 4,959,768 (-)NCBI
UNSW_CanFamBas_1.0274,926,010 - 4,949,602 (-)NCBI
UU_Cfam_GSD_1.02741,707,565 - 41,730,952 (+)NCBI
Tmbim6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,716,130 - 65,736,962 (-)NCBI
SpeTri2.0NW_0049365127,427,926 - 7,448,700 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMBIM6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,674,049 - 15,723,328 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,674,028 - 15,692,944 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TMBIM6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,976,689 - 46,001,021 (+)NCBI
ChlSab1.1 Ensembl1145,976,700 - 46,001,457 (+)Ensembl
Tmbim6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248162,519,839 - 2,540,766 (-)NCBI

Position Markers
BF389213  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,536,121 - 130,536,272 (+)MAPPER
Rnor_6.07141,062,795 - 141,062,945NCBIRnor6.0
Rnor_5.0X115,566,720 - 115,566,870UniSTSRnor5.0
RGSC_v3.47138,148,249 - 138,148,399UniSTSRGSC3.4
Celera7127,018,685 - 127,018,835UniSTS
RH 3.4 Map71076.2UniSTS
Cytogenetic Map7q36UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)751251919145729302Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)771448715145729302Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)791832949145158140Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)791832949145158140Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)796630946141630946Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7100028953145729302Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)7100192194145192194Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)7106564316145729302Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7111519266143965591Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7114825174145729302Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7115922628145729302Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7120746024145692398Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7121654760145729302Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7121986439143965591Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7122421276143965415Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7129412003145729302Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:160
Count of miRNA genes:127
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000022838, ENSRNOT00000045927
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 1 1 1 2
Medium 3 43 56 40 19 40 8 11 74 33 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF118564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY321320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY325130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY325243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X75855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X75856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000084674   ⟹   ENSRNOP00000073494
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7141,053,876 - 141,068,789 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088176   ⟹   ENSRNOP00000074493
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7141,054,494 - 141,068,789 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091050   ⟹   ENSRNOP00000069944
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7141,034,982 - 141,069,989 (+)Ensembl
RefSeq Acc Id: NM_019381   ⟹   NP_062254
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,527,313 - 130,542,118 (+)NCBI
Rnor_6.07141,053,876 - 141,068,789 (+)NCBI
Rnor_5.0X115,557,801 - 115,572,802 (+)NCBI
RGSC_v3.47138,139,438 - 138,154,243 (+)RGD
Celera7127,009,876 - 127,024,679 (+)RGD
Sequence:
RefSeq Acc Id: XM_006257323   ⟹   XP_006257385
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,527,992 - 130,542,567 (+)NCBI
Rnor_6.07141,053,959 - 141,068,870 (+)NCBI
Rnor_5.0X115,557,801 - 115,572,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594666   ⟹   XP_017450155
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,512,428 - 130,543,637 (+)NCBI
Rnor_6.07141,039,433 - 141,070,269 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039078436   ⟹   XP_038934364
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,527,463 - 130,542,567 (+)NCBI
RefSeq Acc Id: XM_039078437   ⟹   XP_038934365
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27130,527,463 - 130,542,567 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_062254   ⟸   NM_019381
- UniProtKB: P55062 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006257385   ⟸   XM_006257323
- Peptide Label: isoform X2
- UniProtKB: P55062 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017450155   ⟸   XM_017594666
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000073494   ⟸   ENSRNOT00000084674
RefSeq Acc Id: ENSRNOP00000069944   ⟸   ENSRNOT00000091050
RefSeq Acc Id: ENSRNOP00000074493   ⟸   ENSRNOT00000088176
RefSeq Acc Id: XP_038934364   ⟸   XM_039078436
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934365   ⟸   XM_039078437
- Peptide Label: isoform X2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695642
Promoter ID:EPDNEW_R6167
Type:multiple initiation site
Name:Tmbim6_1
Description:transmembrane BAX inhibitor motif containing 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07141,053,874 - 141,053,934EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3842 AgrOrtholog
Ensembl Genes ENSRNOG00000055579 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000069944 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073494 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000074493 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000084674 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000088176 UniProtKB/Swiss-Prot
  ENSRNOT00000091050 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6888036 IMAGE-MGC_LOAD
InterPro Bax_inhbtr1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bax_inhibitor_1-related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24822 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72852 IMAGE-MGC_LOAD
NCBI Gene 24822 ENTREZGENE
PANTHER PTHR23291 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Bax1-I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tmbim6 PhenoGen
PROSITE BI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt BI1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q7TMC1_RAT UniProtKB/TrEMBL
UniProt Secondary Q64712 UniProtKB/Swiss-Prot
  Q6PDV4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Tmbim6  transmembrane BAX inhibitor motif containing 6  Tegt  testis enhanced gene transcript  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Tegt  Testis enhanced gene transcript      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression highly expressed postmeiotically in sperm 730005