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Gene: Tmbim6 (transmembrane BAX inhibitor motif containing 6) Mus musculus
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Symbol: Tmbim6
Name: transmembrane BAX inhibitor motif containing 6
Description: Exhibits endoribonuclease inhibitor activity and enzyme binding activity. Involved in several processes, including negative regulation of RNA metabolic process; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; and negative regulation of immunoglobulin secretion. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and mitochondrial membrane. Is expressed in head. Orthologous to human TMBIM6 (transmembrane BAX inhibitor motif containing 6); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; ethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5031406P05Rik; bax inhibitor 1; BI-1; Bi1; Tegt; testis enhanced gene transcript; testis-enhanced gene transcript protein; transmembrane BAX inhibitor motif-containing protein 6
Orthologs:
Homo sapiens (human) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tmbim6 (transmembrane BAX inhibitor motif containing 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmbim6 (transmembrane BAX inhibitor motif containing 6)
Pan paniscus (bonobo/pygmy chimpanzee) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)
Canis lupus familiaris (dog) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmbim6 (transmembrane BAX inhibitor motif containing 6)
Sus scrofa (pig) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)
Chlorocebus sabaeus (African green monkey) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)
Heterocephalus glaber (naked mole-rat) : Tmbim6 (transmembrane BAX inhibitor motif containing 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1599,392,882 - 99,410,049 (+)EnsemblGRCm38mm10GRCm38
GRCm381599,392,947 - 99,410,049 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371599,223,378 - 99,240,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361599,221,020 - 99,238,074 (+)NCBImm8
Celera15101,548,094 - 101,565,263 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tmbim6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11405
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.