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Gene: Tmbim6 (transmembrane BAX inhibitor motif containing 6) Mus musculus
Symbol: Tmbim6
Name: transmembrane BAX inhibitor motif containing 6
Description: Exhibits endoribonuclease inhibitor activity and enzyme binding activity. Involved in several processes, including negative regulation of RNA metabolic process; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; and negative regulation of immunoglobulin secretion. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and mitochondrial membrane. Is expressed in head. Orthologous to human TMBIM6 (transmembrane BAX inhibitor motif containing 6); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; ethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5031406P05Rik; bax inhibitor 1; BI-1; Bi1; Tegt; testis enhanced gene transcript; testis-enhanced gene transcript protein; transmembrane BAX inhibitor motif-containing protein 6
Homo sapiens (human) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tmbim6 (transmembrane BAX inhibitor motif containing 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmbim6 (transmembrane BAX inhibitor motif containing 6)
Pan paniscus (bonobo/pygmy chimpanzee) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)
Canis lupus familiaris (dog) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmbim6 (transmembrane BAX inhibitor motif containing 6)
Sus scrofa (pig) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)
Chlorocebus sabaeus (African green monkey) : TMBIM6 (transmembrane BAX inhibitor motif containing 6)
Heterocephalus glaber (naked mole-rat) : Tmbim6 (transmembrane BAX inhibitor motif containing 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1599,392,882 - 99,410,049 (+)EnsemblGRCm38mm10GRCm38
GRCm381599,392,947 - 99,410,049 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371599,223,378 - 99,240,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361599,221,020 - 99,238,074 (+)NCBImm8
Celera15101,548,094 - 101,565,263 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tmbim6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11405
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.