Apol9a-Apol7a (Apol9a-Apol7a readthrough) - Rat Genome Database

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Gene: Apol9a-Apol7a (Apol9a-Apol7a readthrough) Rattus norvegicus
Analyze
Symbol: Apol9a-Apol7a (Ensembl: Apol7a-Apol9)
Name: Apol9a-Apol7a readthrough (Ensembl:Apol7a-Apol9 readthrough)
RGD ID: 401950492
Description: Predicted to enable lipid binding activity. Predicted to be involved in lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular region; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07058464.1; Apol7a; Apol7b; apolipoprotein L 7a; apolipoprotein L3-like; apolipoprotein L7a; apolipoprotein L7b; LOC133667826; Uncharacterized LOC133667826
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,011,645 - 111,019,326 (-)NCBIGRCr8
mRatBN7.27109,118,559 - 109,149,798 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7109,131,064 - 109,147,649 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.07118,459,981 - 118,468,104 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,473,070 - 118,474,609 (-)NCBIRnor6.0rn6Rnor6.0
Celera7105,466,000 - 105,474,128 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Comparative Map Data
Apol9a-Apol7a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,011,645 - 111,019,326 (-)NCBIGRCr8
mRatBN7.27109,118,559 - 109,149,798 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7109,131,064 - 109,147,649 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.07118,459,981 - 118,468,104 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,473,070 - 118,474,609 (-)NCBIRnor6.0rn6Rnor6.0
Celera7105,466,000 - 105,474,128 (-)NCBICelera
Cytogenetic Map7q34NCBI
Apol7b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391577,306,409 - 77,331,660 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1577,306,409 - 77,331,692 (-)EnsemblGRCm39 Ensembl
GRCm381577,422,209 - 77,447,460 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1577,422,209 - 77,447,492 (-)EnsemblGRCm38mm10GRCm38
MGSCv371577,252,639 - 77,277,890 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361577,249,464 - 77,274,715 (-)NCBIMGSCv36mm8
Cytogenetic Map15D3NCBI
cM Map1536.4NCBI

Variants

.
Variants in Apol9a-Apol7a
53 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001426887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001839107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001844438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001844439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001844440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005487524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005487525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005487526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005487527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000089076   ⟹   ENSRNOP00000070447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7109,131,645 - 109,136,503 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094291   ⟹   ENSRNOP00000084943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7109,131,065 - 109,138,745 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104767   ⟹   ENSRNOP00000087259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7109,131,064 - 109,147,649 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118110   ⟹   ENSRNOP00000079251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7109,131,645 - 109,138,745 (-)Ensembl
RefSeq Acc Id: NM_001426887   ⟹   NP_001413816
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87111,011,645 - 111,019,326 (-)NCBI
RefSeq Acc Id: NP_001413816   ⟸   NM_001426887
- UniProtKB: A0A8I5ZZ37 (UniProtKB/TrEMBL),   A0A8I6GFU1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000070447   ⟸   ENSRNOT00000089076
Ensembl Acc Id: ENSRNOP00000079251   ⟸   ENSRNOT00000118110
Ensembl Acc Id: ENSRNOP00000087259   ⟸   ENSRNOT00000104767
Ensembl Acc Id: ENSRNOP00000084943   ⟸   ENSRNOT00000094291

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:11460844 AgrOrtholog
Ensembl Genes ENSRNOG00000052981 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000089076.2 UniProtKB/TrEMBL
  ENSRNOT00000094291.1 UniProtKB/TrEMBL
  ENSRNOT00000104767.1 UniProtKB/TrEMBL
  ENSRNOT00000118110.1 UniProtKB/TrEMBL
InterPro ApoL UniProtKB/TrEMBL
NCBI Gene LOC133667826 ENTREZGENE
PANTHER APOLIPOPROTEIN L UniProtKB/TrEMBL
  APOLIPOPROTEIN L 7A-RELATED UniProtKB/TrEMBL
Pfam ApoL UniProtKB/TrEMBL
PhenoGen Apol9a-Apol7a PhenoGen
RatGTEx ENSRNOG00000052981 RatGTEx
UniProt A0A0G2JXY3_RAT UniProtKB/TrEMBL
  A0A8I5ZZ37 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G518_RAT UniProtKB/TrEMBL
  A0A8I6GFU1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-10-28 Apol9a-Apol7a  Apol9a-Apol7a readthrough  Apol7b  apolipoprotein L7b  Name and Symbol changed 629549 APPROVED
2024-04-18 Apol7b  apolipoprotein L7b  Apol7a  apolipoprotein L7a  Name and Symbol changed 629549 APPROVED
2024-03-29 Apol7a  apolipoprotein L7a  Apol7a  apolipoprotein L 7a  Name changed 629549 APPROVED
2024-03-29 Apol7a  apolipoprotein L 7a  LOC133667826  Uncharacterized LOC133667826  Name and Symbol changed 629549 APPROVED
2024-03-29 LOC133667826  Uncharacterized LOC133667826  Apol7a  apolipoprotein L 7a  Data Merged 737654 PROVISIONAL
2024-01-09 LOC133667826  Uncharacterized LOC133667826      Symbol and Name status set to provisional 70820 PROVISIONAL
2023-08-03 Apol7a  apolipoprotein L 7a  LOC108351606  uncharacterized LOC108351606  Name and Symbol changed 629549 APPROVED
2022-06-02 LOC108351606  uncharacterized LOC108351606  AABR07058464.1    Data merged from RGD:15007564 737654 PROVISIONAL
2019-11-08 AABR07058464.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2016-08-02 LOC108351606  uncharacterized LOC108351606      Symbol and Name status set to provisional 70820 PROVISIONAL