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Gene: Top1mt (DNA topoisomerase I mitochondrial) Rattus norvegicus
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Symbol: Top1mt
Name: DNA topoisomerase I mitochondrial
RGD ID: 1303177
Description: Predicted to have DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA replication and DNA topological change. Predicted to localize to mitochondrial nucleoid and nucleoplasm. Orthologous to human TOP1MT (DNA topoisomerase I mitochondrial); INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; finasteride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA topoisomerase 1, mitochondrial; DNA topoisomerase I, mitochondrial; mitochondrial topoisomerase I; topoisomerase (DNA) I, mitochondrial
Orthologs:
Homo sapiens (human) : TOP1MT (DNA topoisomerase I mitochondrial)  HGNC  Alliance
Mus musculus (house mouse) : Top1mt (DNA topoisomerase 1, mitochondrial)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Top1mt (DNA topoisomerase I mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : TOP1MT (DNA topoisomerase I mitochondrial)
Sus scrofa (pig) : TOP1MT (DNA topoisomerase I mitochondrial)
Chlorocebus sabaeus (African green monkey) : TOP1MT (DNA topoisomerase I mitochondrial)
Heterocephalus glaber (naked mole-rat) : Top1mt (DNA topoisomerase I mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07116,688,801 - 116,714,421 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,688,701 - 116,712,387 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,582,993 - 116,608,875 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,596,083 - 113,619,109 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17113,630,312 - 113,653,339 (-)NCBI
Celera7103,705,366 - 103,728,376 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Top1mt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303177
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.