Gene: Adcy8 (adenylate cyclase 8) Rattus norvegicus
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Symbol: Adcy8
Name: adenylate cyclase 8
Description: Exhibits several functions, including actin binding activity, calcium- and calmodulin-responsive adenylate cyclase activity, and protein dimerization activity; involved in several processes, including G protein-coupled receptor signaling pathway, cellular chemical homeostasis, and cellular response to organic cyclic compound; localizes to several cellular components, including the caveola, clathrin-coated pit, and dendrite; colocalizes with the actin cytoskeleton; orthologous to human ADCY8 (adenylate cyclase 8); PARTICIPATES IN endothelin signaling pathway; G protein mediated signaling pathway via Galphas family; protein kinase A (PKA) signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; beta-naphthoflavone; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ac8; adenylate cyclase 8 (brain); adenylate cyclase type 8; adenylate cyclase type VIII; adenylyl cyclase 8; adenylyl cyclase 8 variant E; adenylyl cyclase 8 variant F; adenylyl cyclase 8 variant G; adenylyl cyclase 8 variant H; ATP pyrophosphate-lyase 8; ca(2+)/calmodulin-activated adenylyl cyclase; type VIII adenylyl cyclase
Orthologs:
Homo sapiens (human) : ADCY8 (adenylate cyclase 8)  HGNC  Alliance
Mus musculus (house mouse) : Adcy8 (adenylate cyclase 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adcy8 (adenylate cyclase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ADCY8 (adenylate cyclase 8)
Canis lupus familiaris (dog) : ADCY8 (adenylate cyclase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcy8 (adenylate cyclase 8)
Sus scrofa (pig) : ADCY8 (adenylate cyclase 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07105,353,883 - 105,593,372 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07105,301,826 - 105,541,014 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47101,957,807 - 102,210,346 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17101,992,036 - 102,244,576 (-)NCBI
Celera792,997,741 - 93,245,305 (-)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Adcy8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2036
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.