Csad (cysteine sulfinic acid decarboxylase) - Rat Genome Database

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Gene: Csad (cysteine sulfinic acid decarboxylase) Rattus norvegicus
Analyze
Symbol: Csad
Name: cysteine sulfinic acid decarboxylase
RGD ID: 621030
Description: Enables sulfinoalanine decarboxylase activity. Involved in L-cysteine catabolic process to hypotaurine and L-cysteine catabolic process to taurine. Located in cytoplasm. Orthologous to human CSAD (cysteine sulfinic acid decarboxylase); PARTICIPATES IN taurine and hypotaurine metabolic pathway; transsulfuration pathway of homocysteine metabolism; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: aspartate 1-decarboxylase; cysteine-sulfinate decarboxylase; sulfinoalanine decarboxylase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,187,175 - 135,216,495 (-)NCBIGRCr8
mRatBN7.27133,308,571 - 133,337,914 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,308,574 - 133,337,615 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,069,925 - 135,098,194 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,299,292 - 137,327,561 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,283,882 - 137,312,672 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,781,520 - 143,810,880 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,781,702 - 143,793,970 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,579,061 - 141,608,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,917,995 - 140,944,405 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17140,994,262 - 141,036,798 (-)NCBI
Celera7129,743,152 - 129,755,012 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlorohydrocarbon  (EXP)
clobetasol  (ISO)
clofibrate  (ISO)
cocaine  (EXP)
coumarin  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dioxygen  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
finasteride  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP,ISO)
gentamycin  (EXP)
glycidol  (EXP)
indometacin  (ISO)
inulin  (ISO)
lead(0)  (ISO)
linezolid  (EXP)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
Muraglitazar  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
naphthalenes  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP,ISO)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
pirinixic acid  (EXP,ISO)
pravastatin  (EXP,ISO)
propiconazole  (ISO)
Propiverine  (EXP)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
ritodrine  (ISO)
sodium arsenite  (EXP)
sotorasib  (ISO)
succimer  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (EXP)
Tesaglitazar  (EXP)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trametinib  (ISO)
trovafloxacin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IDA,IEA)
cytosol  (TAS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A novel growth-inducible gene that encodes a protein with a conserved cold-shock domain. Ito K, etal., Nucleic Acids Res 1994 Jun 11;22(11):2036-41.
3. Cloning and characterization of rat cysteine sulfinic acid decarboxylase. Kaisaki PJ, etal., Biochim Biophys Acta 1995 May 17;1262(1):79-82.
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. Molecular cloning and sequence analysis of the cDNA encoding rat liver cysteine sulfinate decarboxylase (CSD). Reymond I, etal., Biochim Biophys Acta 1996 Jun 7;1307(2):152-6.
10. Immunocytochemical localization of cysteine sulfinate decarboxylase in astrocytes in the cerebellum and hippocampus: a quantitative double immunofluorescence study with glial fibrillary acidic protein and S-100 protein. Reymond I, etal., Neuroscience. 1996 Nov;75(2):619-33.
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur. Stipanuk MH and Ueki I, J Inherit Metab Dis. 2011 Feb;34(1):17-32. doi: 10.1007/s10545-009-9006-9. Epub 2010 Feb 17.
14. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
15. Cysteine sulfinate decarboxylase (CSD): molecular cloning, sequence and genomic expression in brain. Tappaz M, etal., Adv Exp Med Biol. 1998;442:25-32.
16. Characterization of the cDNA coding for rat brain cysteine sulfinate decarboxylase: brain and liver enzymes are identical proteins encoded by two distinct mRNAs. Tappaz M, etal., J Neurochem 1999 Sep;73(3):903-12.
Additional References at PubMed
PMID:15489334   PMID:17634260   PMID:24639894  


Genomics

Comparative Map Data
Csad
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,187,175 - 135,216,495 (-)NCBIGRCr8
mRatBN7.27133,308,571 - 133,337,914 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,308,574 - 133,337,615 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,069,925 - 135,098,194 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,299,292 - 137,327,561 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,283,882 - 137,312,672 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,781,520 - 143,810,880 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,781,702 - 143,793,970 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,579,061 - 141,608,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,917,995 - 140,944,405 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17140,994,262 - 141,036,798 (-)NCBI
Celera7129,743,152 - 129,755,012 (-)NCBICelera
Cytogenetic Map7q36NCBI
CSAD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,157,663 - 53,181,351 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,157,663 - 53,180,925 (-)EnsemblGRCh38hg38GRCh38
GRCh371253,551,447 - 53,574,709 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,837,714 - 51,860,647 (-)NCBINCBI36Build 36hg18NCBI36
Build 341251,837,714 - 51,860,647NCBI
Celera1253,200,050 - 53,223,033 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,594,015 - 50,617,263 (-)NCBIHuRef
CHM1_11253,517,875 - 53,541,124 (-)NCBICHM1_1
T2T-CHM13v2.01253,123,259 - 53,147,240 (-)NCBIT2T-CHM13v2.0
Csad
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,085,432 - 102,112,685 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,085,434 - 102,113,159 (-)EnsemblGRCm39 Ensembl
GRCm3815102,176,997 - 102,205,052 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,176,999 - 102,204,724 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715102,007,429 - 102,019,474 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,005,032 - 102,017,077 (-)NCBIMGSCv36mm8
Celera15104,331,920 - 104,345,992 (-)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.35NCBI
Csad
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458423,085 - 433,429 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955458423,156 - 449,763 (-)NCBIChiLan1.0ChiLan1.0
CSAD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21041,004,607 - 41,030,621 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11241,001,352 - 41,027,386 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,572,064 - 35,598,077 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,354,360 - 36,379,738 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,354,437 - 36,379,738 (+)Ensemblpanpan1.1panPan2
CSAD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,005,482 - 2,036,703 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl272,005,355 - 2,036,228 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,212,975 - 44,245,324 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0272,008,554 - 2,041,174 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl272,028,291 - 2,041,167 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1272,027,628 - 2,058,651 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,011,598 - 2,043,893 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,613,914 - 44,645,943 (-)NCBIUU_Cfam_GSD_1.0
Csad
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,689,751 - 62,717,369 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,447,461 - 10,474,985 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,447,457 - 10,475,231 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CSAD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,379,288 - 18,410,646 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,379,340 - 18,410,446 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,793,689 - 18,805,868 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CSAD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,256,629 - 49,288,367 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,256,628 - 49,288,112 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037196,772,440 - 196,805,680 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Csad
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,189,366 - 1,228,566 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,190,393 - 1,228,337 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Csad
167 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:373
Count of miRNA genes:209
Interacting mature miRNAs:229
Transcripts:ENSRNOT00000016205
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

Markers in Region
AI576585  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27133,309,191 - 133,309,408 (+)MAPPERmRatBN7.2
Rnor_6.07143,782,141 - 143,782,357NCBIRnor6.0
Rnor_5.07141,579,682 - 141,579,898UniSTSRnor5.0
RGSC_v3.47140,918,446 - 140,918,662UniSTSRGSC3.4
Celera7129,743,603 - 129,743,819UniSTS
RH 3.4 Map71062.1UniSTS
Cytogenetic Map7q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 26 51 35 14 35 1 1 74 35 34 11 1
Low 2 17 6 6 5 6 7 10 7 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH008061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ132615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ132661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC081804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU786150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU906909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M64755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U74492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X94152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000016205   ⟹   ENSRNOP00000016205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,309,011 - 133,337,615 (-)Ensembl
Rnor_6.0 Ensembl7143,781,781 - 143,793,970 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079678   ⟹   ENSRNOP00000073508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,308,574 - 133,336,981 (-)Ensembl
Rnor_6.0 Ensembl7143,781,702 - 143,793,774 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102299   ⟹   ENSRNOP00000087863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,308,574 - 133,323,786 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110884   ⟹   ENSRNOP00000093937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,308,574 - 133,336,981 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113521   ⟹   ENSRNOP00000080923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,309,346 - 133,337,615 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117956   ⟹   ENSRNOP00000085105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,308,574 - 133,336,981 (-)Ensembl
RefSeq Acc Id: NM_021750   ⟹   NP_068518
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,581 (-)NCBI
mRatBN7.27133,308,571 - 133,336,981 (-)NCBI
Rnor_6.07143,781,747 - 143,793,970 (-)NCBI
Rnor_5.07141,579,061 - 141,608,043 (-)NCBI
RGSC_v3.47140,917,995 - 140,944,405 (-)RGD
Celera7129,743,209 - 129,755,012 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242438   ⟹   XP_006242500
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,216,479 (-)NCBI
mRatBN7.27133,308,571 - 133,337,911 (-)NCBI
Rnor_6.07143,781,520 - 143,810,880 (-)NCBI
Rnor_5.07141,579,061 - 141,608,043 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242439   ⟹   XP_006242501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,802 (-)NCBI
mRatBN7.27133,308,571 - 133,337,196 (-)NCBI
Rnor_6.07143,781,520 - 143,810,087 (-)NCBI
Rnor_5.07141,579,061 - 141,608,043 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242440   ⟹   XP_006242502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,216,479 (-)NCBI
mRatBN7.27133,308,571 - 133,337,910 (-)NCBI
Rnor_6.07143,781,520 - 143,810,880 (-)NCBI
Rnor_5.07141,579,061 - 141,608,043 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079834   ⟹   XP_038935762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,423 (-)NCBI
mRatBN7.27133,308,571 - 133,336,708 (-)NCBI
RefSeq Acc Id: XM_039079835   ⟹   XP_038935763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,807 (-)NCBI
mRatBN7.27133,308,571 - 133,337,132 (-)NCBI
RefSeq Acc Id: XM_039079838   ⟹   XP_038935766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,216,486 (-)NCBI
mRatBN7.27133,308,571 - 133,337,914 (-)NCBI
RefSeq Acc Id: XM_063264184   ⟹   XP_063120254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,216,479 (-)NCBI
RefSeq Acc Id: XM_063264185   ⟹   XP_063120255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,237 (-)NCBI
RefSeq Acc Id: XM_063264186   ⟹   XP_063120256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,600 (-)NCBI
RefSeq Acc Id: XM_063264187   ⟹   XP_063120257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,397 (-)NCBI
RefSeq Acc Id: XM_063264188   ⟹   XP_063120258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,216,486 (-)NCBI
RefSeq Acc Id: XM_063264190   ⟹   XP_063120260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,802 (-)NCBI
RefSeq Acc Id: XM_063264191   ⟹   XP_063120261
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,216,493 (-)NCBI
RefSeq Acc Id: XM_063264192   ⟹   XP_063120262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,807 (-)NCBI
RefSeq Acc Id: XM_063264193   ⟹   XP_063120263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,216,494 (-)NCBI
RefSeq Acc Id: XM_063264194   ⟹   XP_063120264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,187,175 - 135,215,802 (-)NCBI
RefSeq Acc Id: XR_010053037
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,189,448 - 135,216,495 (-)NCBI
Protein Sequences
Protein RefSeqs NP_068518 (Get FASTA)   NCBI Sequence Viewer  
  XP_006242500 (Get FASTA)   NCBI Sequence Viewer  
  XP_006242501 (Get FASTA)   NCBI Sequence Viewer  
  XP_006242502 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935762 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935763 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935766 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120254 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120255 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120256 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120257 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120258 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120260 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120261 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120262 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120263 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120264 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB18332 (Get FASTA)   NCBI Sequence Viewer  
  AAC42063 (Get FASTA)   NCBI Sequence Viewer  
  AAD47908 (Get FASTA)   NCBI Sequence Viewer  
  AAD47909 (Get FASTA)   NCBI Sequence Viewer  
  AAH81804 (Get FASTA)   NCBI Sequence Viewer  
  ACF07922 (Get FASTA)   NCBI Sequence Viewer  
  ACG80587 (Get FASTA)   NCBI Sequence Viewer  
  CAA63868 (Get FASTA)   NCBI Sequence Viewer  
  CAB54560 (Get FASTA)   NCBI Sequence Viewer  
  CAB54561 (Get FASTA)   NCBI Sequence Viewer  
  EDL86857 (Get FASTA)   NCBI Sequence Viewer  
  EDL86858 (Get FASTA)   NCBI Sequence Viewer  
  EDL86859 (Get FASTA)   NCBI Sequence Viewer  
  EDL86860 (Get FASTA)   NCBI Sequence Viewer  
  EDL86861 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016205
  ENSRNOP00000016205.5
  ENSRNOP00000073508
  ENSRNOP00000073508.2
  ENSRNOP00000080923
  ENSRNOP00000080923.1
  ENSRNOP00000085105.1
  ENSRNOP00000087863
  ENSRNOP00000087863.1
  ENSRNOP00000093937.1
  ENSRNOP00055039946
  ENSRNOP00060019767
  ENSRNOP00065028614
GenBank Protein Q64611 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_068518   ⟸   NM_021750
- UniProtKB: Q64577 (UniProtKB/Swiss-Prot),   Q546T1 (UniProtKB/Swiss-Prot),   Q9R1F6 (UniProtKB/Swiss-Prot),   Q64611 (UniProtKB/Swiss-Prot),   A6KCT1 (UniProtKB/TrEMBL),   B3VPA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242500   ⟸   XM_006242438
- Peptide Label: isoform X1
- UniProtKB: Q64577 (UniProtKB/Swiss-Prot),   Q546T1 (UniProtKB/Swiss-Prot),   Q9R1F6 (UniProtKB/Swiss-Prot),   Q64611 (UniProtKB/Swiss-Prot),   A6KCT1 (UniProtKB/TrEMBL),   B3VPA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242502   ⟸   XM_006242440
- Peptide Label: isoform X1
- UniProtKB: Q64577 (UniProtKB/Swiss-Prot),   Q546T1 (UniProtKB/Swiss-Prot),   Q9R1F6 (UniProtKB/Swiss-Prot),   Q64611 (UniProtKB/Swiss-Prot),   A6KCT1 (UniProtKB/TrEMBL),   B3VPA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242501   ⟸   XM_006242439
- Peptide Label: isoform X1
- UniProtKB: Q64577 (UniProtKB/Swiss-Prot),   Q546T1 (UniProtKB/Swiss-Prot),   Q9R1F6 (UniProtKB/Swiss-Prot),   Q64611 (UniProtKB/Swiss-Prot),   A6KCT1 (UniProtKB/TrEMBL),   B3VPA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016205   ⟸   ENSRNOT00000016205
RefSeq Acc Id: ENSRNOP00000073508   ⟸   ENSRNOT00000079678
RefSeq Acc Id: XP_038935766   ⟸   XM_039079838
- Peptide Label: isoform X2
- UniProtKB: A0A8L2Q7U2 (UniProtKB/TrEMBL),   B3VPA7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935763   ⟸   XM_039079835
- Peptide Label: isoform X1
- UniProtKB: Q64611 (UniProtKB/Swiss-Prot),   Q64577 (UniProtKB/Swiss-Prot),   Q546T1 (UniProtKB/Swiss-Prot),   Q9R1F6 (UniProtKB/Swiss-Prot),   A6KCT1 (UniProtKB/TrEMBL),   B3VPA7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935762   ⟸   XM_039079834
- Peptide Label: isoform X1
- UniProtKB: Q64611 (UniProtKB/Swiss-Prot),   Q64577 (UniProtKB/Swiss-Prot),   Q546T1 (UniProtKB/Swiss-Prot),   Q9R1F6 (UniProtKB/Swiss-Prot),   A6KCT1 (UniProtKB/TrEMBL),   B3VPA7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000087863   ⟸   ENSRNOT00000102299
RefSeq Acc Id: ENSRNOP00000080923   ⟸   ENSRNOT00000113521
RefSeq Acc Id: ENSRNOP00000093937   ⟸   ENSRNOT00000110884
RefSeq Acc Id: ENSRNOP00000085105   ⟸   ENSRNOT00000117956
RefSeq Acc Id: XP_063120263   ⟸   XM_063264193
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063120261   ⟸   XM_063264191
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063120258   ⟸   XM_063264188
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063120254   ⟸   XM_063264184
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120262   ⟸   XM_063264192
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063120260   ⟸   XM_063264190
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063120264   ⟸   XM_063264194
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063120256   ⟸   XM_063264186
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120257   ⟸   XM_063264187
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120255   ⟸   XM_063264185
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64611-F1-model_v2 AlphaFold Q64611 1-493 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695692
Promoter ID:EPDNEW_R6217
Type:initiation region
Name:Csad_1
Description:cysteine sulfinic acid decarboxylase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07143,794,012 - 143,794,072EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621030 AgrOrtholog
BioCyc Gene G2FUF-31947 BioCyc
BioCyc Pathway PWY-5331 [taurine biosynthesis I] BioCyc
BioCyc Pathway Image PWY-5331 BioCyc
Ensembl Genes ENSRNOG00000011573 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055028018 UniProtKB/Swiss-Prot
  ENSRNOG00060014471 UniProtKB/Swiss-Prot
  ENSRNOG00065020858 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000016205.7 UniProtKB/TrEMBL
  ENSRNOT00000079678 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000079678.2 UniProtKB/Swiss-Prot
  ENSRNOT00000102299.1 UniProtKB/TrEMBL
  ENSRNOT00000110884.1 UniProtKB/TrEMBL
  ENSRNOT00000113521.1 UniProtKB/TrEMBL
  ENSRNOT00000117956.1 UniProtKB/TrEMBL
  ENSRNOT00055048592 UniProtKB/Swiss-Prot
  ENSRNOT00060024818 UniProtKB/Swiss-Prot
  ENSRNOT00065035510 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.640.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/TrEMBL
  3.90.1150.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7106840 IMAGE-MGC_LOAD
InterPro PyrdxlP-dep_de-COase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_small UniProtKB/TrEMBL
  Pyridoxal-P_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:60356 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93461 IMAGE-MGC_LOAD
NCBI Gene 60356 ENTREZGENE
PANTHER CYSTEINE SULFINIC ACID DECARBOXYLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLUTAMATE DECARBOXYLASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pyridoxal_deC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Csad PhenoGen
PROSITE DDC_GAD_HDC_YDC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011573 RatGTEx
  ENSRNOG00055028018 RatGTEx
  ENSRNOG00060014471 RatGTEx
  ENSRNOG00065020858 RatGTEx
Superfamily-SCOP SSF53383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K5P7_RAT UniProtKB/TrEMBL
  A0A8I5ZQK7_RAT UniProtKB/TrEMBL
  A0A8I6A6P6_RAT UniProtKB/TrEMBL
  A0A8I6AMR0_RAT UniProtKB/TrEMBL
  A0A8I6GBN4_RAT UniProtKB/TrEMBL
  A0A8L2Q7U2 ENTREZGENE, UniProtKB/TrEMBL
  A6KCT1 ENTREZGENE, UniProtKB/TrEMBL
  A6KCT5_RAT UniProtKB/TrEMBL
  B3VPA7 ENTREZGENE, UniProtKB/TrEMBL
  B5LSW7_RAT UniProtKB/TrEMBL
  CSAD_RAT UniProtKB/Swiss-Prot
  Q546T1 ENTREZGENE
  Q64577 ENTREZGENE
  Q64611 ENTREZGENE
  Q9R1F5_RAT UniProtKB/TrEMBL
  Q9R1F6 ENTREZGENE
UniProt Secondary Q546T1 UniProtKB/Swiss-Prot
  Q64577 UniProtKB/Swiss-Prot
  Q9R1F6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Csad  cysteine sulfinic acid decarboxylase    cysteine-sulfinate decarboxylase  Name updated 1299863 APPROVED
2002-08-07 Csad  cysteine-sulfinate decarboxylase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation expression and activity are inhibited by triiodothyronine and estrogen 632596