(+)-catechin increases expression ISO RGD:733712 6480464 Catechin results in increased expression of ATF4 mRNA CTD PMID:15465739 (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ATF4 mRNA] CTD PMID:31150632 (-)-citrinin increases expression ISO RGD:733712 6480464 Citrinin results in increased expression of ATF4 mRNA CTD PMID:21844328 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:733712 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of ATF4 mRNA CTD PMID:22079256 (R)-lipoic acid multiple interactions ISO RGD:733713 6480464 Thioctic Acid inhibits the reaction [arsenic trioxide results in increased expression of ATF4 mRNA], Thioctic Acid inhibits the reaction [arsenic trioxide results in increased expression of ATF4 protein] CTD PMID:23892647 (R)-lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:30605698 (S)-amphetamine increases expression EXP 6480464 Dextroamphetamine results in increased expression of ATF4 mRNA CTD PMID:18305237 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO RGD:733713 6480464 o, p'-DDT results in increased expression of ATF4 mRNA CTD PMID:24096037 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression EXP 6480464 o, p'-DDT results in increased expression of ATF4 mRNA CTD PMID:24096037 1,2-dimethylhydrazine multiple interactions EXP 6480464 trans-3-(4'-hydroxyphenyl)-2-propenoic acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of ATF4 protein] CTD PMID:29879413 1,2-dimethylhydrazine decreases expression EXP 6480464 1, 2-Dimethylhydrazine results in decreased expression of ATF4 protein CTD PMID:29879413 1,4-dithiothreitol increases expression ISO RGD:733712 6480464 Dithiothreitol results in increased expression of ATF4 mRNA CTD PMID:27226639 1,4-dithiothreitol increases expression ISO RGD:733713 6480464 Dithiothreitol results in increased expression of ATF4 mRNA CTD PMID:27226639 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of ATF4 mRNA CTD PMID:20551477 1-naphthyl isothiocyanate multiple interactions ISO RGD:733712 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of ATF4 mRNA CTD PMID:27344345 17alpha-ethynylestradiol multiple interactions ISO RGD:733713 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATF4 mRNA, fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ATF4 mRNA] CTD PMID:16467188 , PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of ATF4 mRNA CTD PMID:16174780 more ... 17alpha-ethynylestradiol increases expression ISO RGD:733713 6480464 Ethinyl Estradiol results in increased expression of ATF4 mRNA CTD PMID:16174780 more ... 17beta-estradiol increases expression ISO RGD:733713 6480464 Estradiol results in increased expression of ATF4 mRNA CTD PMID:25210133 17beta-estradiol affects expression ISO RGD:733713 6480464 Estradiol affects the expression of ATF4 mRNA CTD PMID:15598610 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:733712 6480464 Dihydrotestosterone results in increased expression of ATF4 protein CTD PMID:23405127 1H-pyrazole increases expression ISO RGD:733713 6480464 pyrazole results in increased expression of ATF4 mRNA CTD PMID:17945193 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:733713 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:30029115 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:733713 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:733713 6480464 2 more ... CTD PMID:25639565 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:733713 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:733713 6480464 Tetrachlorodibenzodioxin affects the expression of ATF4 mRNA CTD PMID:21570461 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:733712 6480464 [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in increased expression of ATF4 mRNA CTD PMID:29704546 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:733712 6480464 Tetrachlorodibenzodioxin affects the expression of ATF4 mRNA CTD PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:733713 6480464 Tetrachlorodibenzodioxin results in increased expression of ATF4 mRNA CTD PMID:16467188 , PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:733713 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATF4 mRNA, fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ATF4 mRNA] CTD PMID:16467188 , PMID:17942748 2,3-dimethoxynaphthalene-1,4-dione increases expression ISO RGD:733712 6480464 2 more ... CTD PMID:21703327 2-amino-2-deoxy-D-galactopyranose multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of ATF4 mRNA] more ... CTD PMID:28844859 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:733713 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] more ... CTD PMID:30602124 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:733713 6480464 Glucosamine results in increased expression of ATF4 mRNA, Glucosamine results in increased expression of ATF4 protein CTD PMID:30602124 2-butoxyethanol increases expression ISO RGD:733713 6480464 n-butoxyethanol results in increased expression of ATF4 mRNA CTD PMID:19812364 2-hydroxypropanoic acid increases expression ISO RGD:733712 6480464 Lactic Acid results in increased expression of ATF4 mRNA CTD PMID:30851411 3H-1,2-dithiole-3-thione multiple interactions ISO RGD:733713 6480464 1, 2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of ATF4 mRNA] CTD PMID:22959925 4,4'-diaminodiphenylmethane decreases expression ISO RGD:733713 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of ATF4 mRNA CTD PMID:18648102 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions ISO RGD:733713 6480464 4 more ... CTD PMID:27638049 4-hydroxynon-2-enal increases expression EXP 6480464 4-hydroxy-2-nonenal results in increased expression of ATF4 mRNA, 4-hydroxy-2-nonenal results in increased expression of ATF4 protein CTD PMID:24291486 4-hydroxynon-2-enal multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF4 protein] CTD PMID:24291486 4-hydroxyphenyl retinamide decreases response to substance ISO RGD:733712 6480464 ATF4 results in decreased susceptibility to Fenretinide CTD PMID:20022965 4-hydroxyphenyl retinamide increases expression ISO RGD:733712 6480464 Fenretinide results in increased expression of ATF4 mRNA CTD PMID:16671099 , PMID:17353921 4-hydroxyphenyl retinamide multiple interactions ISO RGD:733712 6480464 ATF4 mutant form inhibits the reaction [Fenretinide results in increased expression of PMAIP1 mRNA] more ... CTD PMID:20022965 4-hydroxyphenyl retinamide affects expression ISO RGD:733712 6480464 Fenretinide affects the expression of ATF4 mRNA, Fenretinide affects the expression of ATF4 protein CTD PMID:20022965 4-phenylbutyric acid multiple interactions ISO RGD:733712 6480464 4-phenylbutyric acid inhibits the reaction [Acrylamide results in increased expression of ATF4 protein] more ... CTD PMID:27470132 more ... 4-phenylbutyric acid multiple interactions ISO RGD:733713 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA], 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein] CTD PMID:30602124 4-phenylbutyric acid decreases expression EXP 6480464 4-phenylbutyric acid results in decreased expression of ATF4 protein CTD PMID:27484784 , PMID:28844859 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [6-chloro-2 more ... CTD PMID:27484784 more ... 4-tert-Octylphenol decreases expression EXP 6480464 4-tert-octylphenol results in decreased expression of ATF4 mRNA CTD PMID:17011747 4-tert-Octylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of ATF4 mRNA CTD PMID:17011747 5-fluorouracil increases expression ISO RGD:733712 6480464 Fluorouracil results in increased expression of ATF4 protein CTD PMID:29879413 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide increases expression EXP 6480464 6-chloro-2 more ... CTD PMID:29653943 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [6-chloro-2 more ... CTD PMID:29653943 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO RGD:733712 6480464 Uric Acid inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of ATF4 mRNA] CTD PMID:21703327 acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester multiple interactions ISO RGD:733712 6480464 nitazoxanide promotes the reaction [EIF2A protein results in increased expression of ATF4 protein] CTD PMID:19664635 acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester increases expression ISO RGD:733712 6480464 nitazoxanide results in increased expression of ATF4 protein CTD PMID:19664635 acetylsalicylic acid decreases expression ISO RGD:733712 6480464 Aspirin results in decreased expression of ATF4 mRNA CTD PMID:15928584 acrolein multiple interactions ISO RGD:733712 6480464 Acrolein results in increased expression of and affects the localization of ATF4 protein CTD PMID:18951912 acrolein increases expression EXP 6480464 Acrolein results in increased expression of ATF4 mRNA, Acrolein results in increased expression of ATF4 protein CTD PMID:28119953 acrylamide multiple interactions ISO RGD:733712 6480464 4-phenylbutyric acid inhibits the reaction [Acrylamide results in increased expression of ATF4 protein], Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of ATF4 protein] CTD PMID:27634458 acrylamide increases expression ISO RGD:733712 6480464 Acrylamide results in increased expression of ATF4 protein CTD PMID:27634458 actinomycin D multiple interactions ISO RGD:733712 6480464 Dactinomycin inhibits the reaction [Bortezomib results in increased expression of ATF4 mRNA] more ... CTD PMID:20022965 aldehydo-D-glucosamine increases expression ISO RGD:733713 6480464 Glucosamine results in increased expression of ATF4 mRNA, Glucosamine results in increased expression of ATF4 protein CTD PMID:30602124 aldehydo-D-glucosamine multiple interactions ISO RGD:733713 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] more ... CTD PMID:30602124 aldehydo-D-glucose increases expression ISO RGD:733713 6480464 Glucose deficiency results in increased expression of ATF4 mRNA CTD PMID:27226639 aldehydo-D-glucose increases expression ISO RGD:733712 6480464 Glucose deficiency results in increased expression of ATF4 protein CTD PMID:31022492 aldehydo-D-glucose multiple interactions ISO RGD:733712 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF4 protein] more ... CTD PMID:29427785 , PMID:31022492 all-trans-retinal increases expression ISO RGD:733712 6480464 Retinaldehyde results in increased expression of ATF4 mRNA CTD PMID:25331497 all-trans-retinoic acid increases expression ISO RGD:733713 6480464 Tretinoin results in increased expression of ATF4 mRNA, Tretinoin results in increased expression of ATF4 protein CTD PMID:22498432 alpha-D-galactose multiple interactions ISO RGD:733712 6480464 [Galactose co-treated with Glucose deficiency] promotes the reaction [leflunomide results in increased expression of ATF4 protein] CTD PMID:29427785 amino acid multiple interactions ISO RGD:733713 6480464 EIF2AK4 gene mutant form inhibits the reaction [Amino Acids deficiency results in increased expression of ATF4 protein] CTD PMID:29449374 amino acid increases expression ISO RGD:733713 6480464 Amino Acids deficiency results in increased expression of ATF4 protein CTD PMID:29449374 amiodarone increases expression ISO RGD:733712 6480464 Amiodarone results in increased expression of ATF4 protein CTD PMID:21292685 amiodarone increases expression ISO RGD:733713 6480464 Amiodarone results in increased expression of ATF4 mRNA CTD PMID:28962527 amiodarone multiple interactions ISO RGD:733713 6480464 1-(3, 4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of ATF4 mRNA] CTD PMID:28962527 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ATF4 mRNA CTD PMID:16483693 amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of ATF4 mRNA CTD PMID:30779732 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA] CTD PMID:20920558 antirheumatic drug increases expression ISO RGD:733712 6480464 Antirheumatic Agents results in increased expression of ATF4 mRNA CTD PMID:24449571 Aroclor 1254 decreases expression ISO RGD:733713 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of ATF4 mRNA CTD PMID:23650126 arsenite(3-) increases expression ISO RGD:733712 6480464 arsenite results in increased expression of ATF4 protein CTD PMID:14604972 arsenite(3-) increases phosphorylation ISO RGD:733712 6480464 arsenite results in increased phosphorylation of ATF4 protein CTD PMID:22959463 arsenite(3-) multiple interactions ISO RGD:733712 6480464 ATF4 mutant form inhibits the reaction [arsenite results in increased expression of SLC38A2 mRNA], ATF4 mutant form inhibits the reaction [arsenite results in increased expression of SLC38A2 protein] CTD PMID:22215663 arsenite(3-) increases expression ISO RGD:733713 6480464 arsenite results in increased expression of ATF4 mRNA, arsenite results in increased expression of ATF4 protein CTD PMID:20589738 , PMID:29109149 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of ATF4 mRNA, arsenite results in increased expression of ATF4 protein CTD PMID:18226606 , PMID:22425709 arsenous acid increases expression ISO RGD:733713 6480464 Arsenic Trioxide results in increased expression of ATF4 mRNA, Arsenic Trioxide results in increased expression of ATF4 protein CTD PMID:23892647 , PMID:27638049 arsenous acid multiple interactions ISO RGD:733713 6480464 1 more ... CTD PMID:23892647 more ... arsenous acid multiple interactions ISO RGD:733712 6480464 Dasatinib inhibits the reaction [Arsenic Trioxide results in increased expression of ATF4 protein] CTD PMID:29266867 arsenous acid increases expression ISO RGD:733712 6480464 Arsenic Trioxide results in increased expression of ATF4 protein CTD PMID:29266867 atrazine decreases expression ISO RGD:733712 6480464 Atrazine results in decreased expression of ATF4 mRNA CTD PMID:22378314 bathocuproine disulfonic acid multiple interactions ISO RGD:733712 6480464 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA] CTD PMID:15477007 benzalkonium chloride decreases expression ISO RGD:733712 6480464 Benzalkonium Compounds results in decreased expression of ATF4 mRNA CTD PMID:28236482 benzene affects expression EXP 6480464 Benzene affects the expression of ATF4 mRNA CTD PMID:15878777 benzo[a]pyrene affects activity ISO RGD:733712 6480464 Benzo(a)pyrene affects the activity of ATF4 protein CTD PMID:20624995 benzo[a]pyrene increases expression ISO RGD:733713 6480464 Benzo(a)pyrene results in increased expression of ATF4 mRNA CTD PMID:21569818 , PMID:22228805 benzo[a]pyrene decreases expression ISO RGD:733713 6480464 Benzo(a)pyrene results in decreased expression of ATF4 mRNA CTD PMID:19770486 benzo[a]pyrene diol epoxide I increases expression ISO RGD:733712 6480464 7 more ... CTD PMID:19150397 bepridil increases expression ISO RGD:733712 6480464 Bepridil results in increased expression of ATF4 protein CTD PMID:21292685 beta-D-glucosamine increases expression ISO RGD:733713 6480464 Glucosamine results in increased expression of ATF4 mRNA, Glucosamine results in increased expression of ATF4 protein CTD PMID:30602124 beta-D-glucosamine multiple interactions ISO RGD:733713 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] more ... CTD PMID:30602124 bis(2-chloroethyl) sulfide increases expression ISO RGD:733713 6480464 Mustard Gas results in increased expression of ATF4 mRNA CTD PMID:15674843 bis(2-chloroethyl) sulfide affects expression EXP 6480464 Mustard Gas affects the expression of ATF4 mRNA CTD PMID:15651846 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:733713 6480464 Diethylhexyl Phthalate results in decreased expression of ATF4 mRNA CTD PMID:19245819 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of ATF4 mRNA CTD PMID:25280772 bisphenol A decreases expression ISO RGD:733712 6480464 bisphenol A results in decreased expression of ATF4 mRNA CTD PMID:20678512 bisphenol A affects expression ISO RGD:733712 6480464 bisphenol A affects the expression of ATF4 mRNA CTD PMID:30903817 bisphenol A affects methylation ISO RGD:733713 6480464 bisphenol A affects the methylation of ATF4 promoter CTD PMID:27334623 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ATF4 mRNA CTD PMID:25181051 more ... bisphenol A increases expression ISO RGD:733713 6480464 bisphenol A results in increased expression of ATF4 mRNA CTD PMID:12233820 , PMID:28910977 bongkrekic acid multiple interactions ISO RGD:733712 6480464 Bongkrekic Acid inhibits the reaction [leflunomide results in increased expression of ATF4 protein] CTD PMID:29427785 boric acid increases expression ISO RGD:733712 6480464 boric acid results in increased expression of ATF4 mRNA, boric acid results in increased expression of ATF4 protein CTD PMID:25425213 , PMID:27587023 bortezomib multiple interactions ISO RGD:733713 6480464 1 more ... CTD PMID:15509775 bortezomib increases expression ISO RGD:733712 6480464 Bortezomib results in increased expression of ATF4 mRNA, Bortezomib results in increased expression of ATF4 protein CTD PMID:15509775 more ... bortezomib decreases response to substance ISO RGD:733712 6480464 ATF4 results in decreased susceptibility to Bortezomib CTD PMID:20022965 bortezomib multiple interactions ISO RGD:733712 6480464 1 more ... CTD PMID:15509775 , PMID:20022965 bortezomib increases expression ISO RGD:733713 6480464 Bortezomib results in increased expression of ATF4 protein CTD PMID:15509775 brefeldin A increases expression ISO RGD:733712 6480464 Brefeldin A results in increased expression of ATF4 protein CTD PMID:24865413 , PMID:27358234 cadmium dichloride decreases response to substance ISO RGD:733712 6480464 ATF4 protein results in decreased susceptibility to Cadmium Chloride, ATF4 results in decreased susceptibility to Cadmium Chloride CTD PMID:21809093 , PMID:24057571 cadmium dichloride affects activity ISO RGD:733712 6480464 Cadmium Chloride affects the activity of ATF4 protein CTD PMID:25596134 cadmium dichloride multiple interactions ISO RGD:733712 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of ATF4] more ... CTD PMID:24057571 cadmium dichloride increases expression ISO RGD:733712 6480464 Cadmium Chloride results in increased expression of ATF4 more ... CTD PMID:21809093 more ... cadmium sulfate multiple interactions ISO RGD:733712 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of ATF4 mRNA CTD PMID:18654764 camptothecin multiple interactions ISO RGD:733712 6480464 Glutathione inhibits the reaction [Camptothecin results in increased expression of ATF4 protein], MYC protein affects the reaction [Camptothecin results in increased expression of ATF4 protein] CTD PMID:30266318 camptothecin increases expression ISO RGD:733712 6480464 Camptothecin results in increased expression of ATF4 protein CTD PMID:30266318 cannabidiol increases expression ISO RGD:733713 6480464 Cannabidiol results in increased expression of ATF4 mRNA CTD PMID:21542829 capsaicin increases expression ISO RGD:733712 6480464 Capsaicin results in increased expression of ATF4 protein CTD PMID:18533110 , PMID:19139269 capsaicin affects localization ISO RGD:733712 6480464 Capsaicin affects the localization of ATF4 protein CTD PMID:20925121 capsaicin multiple interactions ISO RGD:733712 6480464 Cycloheximide inhibits the reaction [Capsaicin results in increased expression of ATF4 protein] CTD PMID:18533110 carbamazepine increases expression ISO RGD:733712 6480464 Carbamazepine results in increased expression of ATF4 mRNA CTD PMID:24752500 carbamazepine affects expression ISO RGD:733712 6480464 Carbamazepine affects the expression of ATF4 mRNA CTD PMID:24752500 carbon nanotube decreases expression ISO RGD:733713 6480464 Nanotubes, Carbon results in decreased expression of ATF4 mRNA CTD PMID:25620056 carbon nanotube increases expression ISO RGD:733713 6480464 Nanotubes, Carbon results in increased expression of ATF4 mRNA CTD PMID:25554681 carbon nanotube affects expression ISO RGD:733713 6480464 Nanotubes, Carbon analog affects the expression of ATF4 mRNA CTD PMID:25554681 carboxy-PTIO increases expression ISO RGD:733712 6480464 1 more ... CTD PMID:21703327 carboxy-PTIO multiple interactions ISO RGD:733712 6480464 1 more ... CTD PMID:21703327 chloroacetaldehyde affects activity ISO RGD:733712 6480464 chloroacetaldehyde affects the activity of ATF4 protein CTD PMID:25596134 chloroacetic acid increases expression ISO RGD:733713 6480464 chloroacetic acid results in increased expression of ATF4 protein CTD PMID:25451595 chloroacetic acid multiple interactions ISO RGD:733713 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of ATF4 protein] CTD PMID:25451595 chloropicrin affects expression ISO RGD:733712 6480464 chloropicrin affects the expression of ATF4 mRNA CTD PMID:26352163 chloroquine multiple interactions EXP 6480464 Chloroquine promotes the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:29870746 chlorpromazine multiple interactions ISO RGD:733712 6480464 [Chlorpromazine co-treated with Cholic Acids] affects the expression of ATF4 mRNA CTD PMID:27344345 chlorpromazine affects activity EXP 6480464 Chlorpromazine affects the activity of ATF4 protein CTD PMID:25596134 chromium(6+) increases expression ISO RGD:733712 6480464 chromium hexavalent ion results in increased expression of ATF4 mRNA CTD PMID:30690063 chrysene increases expression ISO RGD:733713 6480464 chrysene results in increased expression of ATF4 mRNA CTD PMID:26377693 cibenzoline increases expression ISO RGD:733712 6480464 cifenline results in increased expression of ATF4 protein CTD PMID:21292685 cidofovir anhydrous affects activity ISO RGD:733712 6480464 Cidofovir affects the activity of ATF4 protein CTD PMID:25596134 cisplatin increases expression ISO RGD:733713 6480464 Cisplatin results in increased expression of ATF4 protein CTD PMID:21616140 cisplatin affects activity ISO RGD:733712 6480464 Cisplatin affects the activity of ATF4 protein CTD PMID:25596134 cisplatin decreases expression ISO RGD:733713 6480464 Cisplatin results in decreased expression of ATF4 mRNA CTD PMID:25270620 cisplatin multiple interactions ISO RGD:733713 6480464 salubrinal promotes the reaction [Cisplatin results in increased expression of ATF4 protein] CTD PMID:21616140 clodronic acid affects activity ISO RGD:733712 6480464 Clodronic Acid affects the activity of ATF4 protein CTD PMID:25596134 clofibrate multiple interactions ISO RGD:733713 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ATF4 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ATF4 mRNA] CTD PMID:17585979 clofibrate decreases expression ISO RGD:733713 6480464 Clofibrate results in decreased expression of ATF4 mRNA CTD PMID:17585979 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATF4 mRNA CTD PMID:17602206 cobalt dichloride multiple interactions ISO RGD:733712 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of ATF4 mRNA CTD PMID:18654764 cocaine increases expression EXP 6480464 Cocaine results in increased expression of ATF4, Cocaine results in increased expression of ATF4 mRNA CTD PMID:18593214 , PMID:23644055 copper atom increases expression ISO RGD:733713 6480464 Copper results in increased expression of ATF4 CTD PMID:25159668 copper(0) increases expression ISO RGD:733713 6480464 Copper results in increased expression of ATF4 CTD PMID:25159668 copper(II) chloride multiple interactions EXP 6480464 [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA, pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA] CTD PMID:20920558 copper(II) sulfate increases expression ISO RGD:733712 6480464 Copper Sulfate results in increased expression of ATF4 mRNA CTD PMID:19549813 crocidolite asbestos affects expression ISO RGD:733712 6480464 Asbestos, Crocidolite affects the expression of ATF4 mRNA CTD PMID:17331233 crocidolite asbestos increases expression ISO RGD:733712 6480464 Asbestos, Crocidolite results in increased expression of ATF4 mRNA CTD PMID:25757056 cycloheximide multiple interactions ISO RGD:733712 6480464 Cycloheximide inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of ATF4]], Cycloheximide inhibits the reaction [Capsaicin results in increased expression of ATF4 protein] CTD PMID:18533110 , PMID:24057571 cycloheximide multiple interactions ISO RGD:733713 6480464 Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein] CTD PMID:23593480 cyclosporin A increases expression ISO RGD:733712 6480464 Cyclosporine results in increased expression of ATF4 mRNA CTD PMID:24973091 cyclosporin A affects activity ISO RGD:733712 6480464 Cyclosporine affects the activity of ATF4 protein CTD PMID:25596134 cyclosporin A affects activity EXP 6480464 Cyclosporine affects the activity of ATF4 protein CTD PMID:25596134 cyclosporin A multiple interactions ISO RGD:733712 6480464 [Cyclosporine co-treated with Cholic Acids] affects the expression of ATF4 mRNA CTD PMID:27344345 cyclosporin A increases expression ISO RGD:733713 6480464 Cyclosporine results in increased expression of ATF4 mRNA CTD PMID:23958496 cylindrospermopsin increases expression ISO RGD:733712 6480464 cylindrospermopsin results in increased expression of ATF4 mRNA CTD PMID:24921660 D-glucose increases expression ISO RGD:733713 6480464 Glucose deficiency results in increased expression of ATF4 mRNA CTD PMID:27226639 D-glucose increases expression ISO RGD:733712 6480464 Glucose deficiency results in increased expression of ATF4 protein CTD PMID:31022492 D-glucose multiple interactions ISO RGD:733712 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF4 protein] more ... CTD PMID:29427785 , PMID:31022492 dantrolene decreases expression EXP 6480464 Dantrolene results in decreased expression of ATF4 protein CTD PMID:15921666 dexamethasone decreases expression ISO RGD:733713 6480464 Dexamethasone results in decreased expression of ATF4 mRNA CTD PMID:22733784 diarsenic trioxide increases expression ISO RGD:733713 6480464 Arsenic Trioxide results in increased expression of ATF4 mRNA, Arsenic Trioxide results in increased expression of ATF4 protein CTD PMID:23892647 , PMID:27638049 diarsenic trioxide multiple interactions ISO RGD:733712 6480464 Dasatinib inhibits the reaction [Arsenic Trioxide results in increased expression of ATF4 protein] CTD PMID:29266867 diarsenic trioxide increases expression ISO RGD:733712 6480464 Arsenic Trioxide results in increased expression of ATF4 protein CTD PMID:29266867 diarsenic trioxide multiple interactions ISO RGD:733713 6480464 1 more ... CTD PMID:23892647 more ... dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of ATF4 mRNA CTD PMID:21266533 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of ATF4 mRNA CTD PMID:17379624 , PMID:21266533 dibutyl phthalate increases expression ISO RGD:733713 6480464 Dibutyl Phthalate results in increased expression of ATF4 mRNA CTD PMID:17361019 , PMID:21266533 diclofenac affects expression ISO RGD:733712 6480464 Diclofenac affects the expression of ATF4 mRNA CTD PMID:24752500 diclofenac increases expression ISO RGD:733712 6480464 Diclofenac results in increased expression of ATF4 mRNA CTD PMID:24752500 , PMID:27313093 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of ATF4 mRNA CTD PMID:17011747 dihydrocapsaicin increases expression ISO RGD:733712 6480464 dihydrocapsaicin results in increased expression of ATF4 protein CTD PMID:19139269 dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of ATF4 mRNA CTD PMID:16122865 dimethylarsinic acid increases expression ISO RGD:733712 6480464 Cacodylic Acid results in increased expression of ATF4 mRNA CTD PMID:23221991 dimethylarsinous acid increases expression EXP 6480464 dimethylarsinous acid results in increased expression of ATF4 mRNA CTD PMID:22425709 dioxygen increases expression ISO RGD:733712 6480464 Oxygen deficiency results in increased expression of ATF4 protein, Oxygen results in increased expression of ATF4 mRNA CTD PMID:14604972 , PMID:27103661 dioxygen multiple interactions ISO RGD:733713 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ATF4 mRNA CTD PMID:30529165 dioxygen affects activity ISO RGD:733712 6480464 Oxygen deficiency affects the activity of ATF4 protein CTD PMID:25596134 dioxygen decreases expression ISO RGD:733712 6480464 Oxygen results in decreased expression of ATF4 protein CTD PMID:14604972 dioxygen affects stability ISO RGD:733712 6480464 Oxygen deficiency affects the stability of ATF4 protein CTD PMID:14604972 doxorubicin multiple interactions ISO RGD:733712 6480464 Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein] CTD PMID:16298333 doxorubicin decreases expression ISO RGD:733712 6480464 Doxorubicin results in decreased expression of ATF4 mRNA CTD PMID:16298333 elemental selenium increases expression ISO RGD:733712 6480464 Selenium results in increased expression of ATF4 mRNA CTD PMID:19244175 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of ATF4 mRNA CTD PMID:29391264 epoxomicin multiple interactions ISO RGD:733713 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 erlotinib hydrochloride increases expression EXP 6480464 Erlotinib Hydrochloride results in increased expression of ATF4 protein CTD PMID:24768708 ethanol increases expression ISO RGD:733713 6480464 Ethanol results in increased expression of ATF4 mRNA, Ethanol results in increased expression of ATF4 protein CTD PMID:28119953 ethanol multiple interactions ISO RGD:733712 6480464 [[Gasoline co-treated with Ethanol] results in increased chemical synthesis of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of ATF4 mRNA, resveratrol inhibits the reaction [Ethanol results in increased expression of ATF4 protein] CTD PMID:24224909 , PMID:29432896 ethanol increases expression ISO RGD:733712 6480464 Ethanol results in increased expression of ATF4 protein CTD PMID:24224909 ethanol increases expression EXP 6480464 Ethanol results in increased expression of ATF4 mRNA, Ethanol results in increased expression of ATF4 protein CTD PMID:28119953 ethanol multiple interactions ISO RGD:733713 6480464 Hydralazine inhibits the reaction [Ethanol results in increased expression of ATF4 mRNA] CTD PMID:28119953 etoposide decreases expression ISO RGD:733713 6480464 Etoposide results in decreased expression of ATF4 mRNA CTD PMID:25270620 fangchinoline multiple interactions ISO RGD:733712 6480464 Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of ATF4 protein] CTD PMID:28754437 fangchinoline increases expression ISO RGD:733712 6480464 fangchinoline results in increased expression of ATF4 protein CTD PMID:28754437 fenofibrate affects activity ISO RGD:733712 6480464 Fenofibrate affects the activity of ATF4 protein CTD PMID:25596134 fenofibrate affects activity EXP 6480464 Fenofibrate affects the activity of ATF4 protein CTD PMID:25596134 fluoranthene multiple interactions ISO RGD:733713 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of ATF4 mRNA CTD PMID:28329830 flutamide increases expression EXP 6480464 Flutamide results in increased expression of ATF4 mRNA CTD PMID:24136188 fructose increases expression EXP 6480464 Fructose results in increased expression of ATF4 mRNA CTD PMID:15150374 fulvestrant multiple interactions ISO RGD:733713 6480464 fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ATF4 mRNA], fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ATF4 mRNA] CTD PMID:16467188 furan increases expression ISO RGD:733713 6480464 furan results in increased expression of ATF4 mRNA CTD PMID:24183702 gadolinium trichloride affects expression EXP 6480464 gadolinium chloride affects the expression of ATF4 mRNA CTD PMID:21198628 galactose multiple interactions ISO RGD:733712 6480464 [Galactose co-treated with Glucose deficiency] promotes the reaction [leflunomide results in increased expression of ATF4 protein] CTD PMID:29427785 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of ATF4 mRNA CTD PMID:22061828 geraniol multiple interactions ISO RGD:733712 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of ATF4 protein] CTD PMID:30141137 glafenine increases expression EXP 6480464 Glafenine results in increased expression of ATF4 mRNA CTD PMID:24136188 glucose increases expression ISO RGD:733713 6480464 Glucose deficiency results in increased expression of ATF4 mRNA CTD PMID:27226639 glucose increases expression ISO RGD:733712 6480464 Glucose deficiency results in increased expression of ATF4 protein CTD PMID:31022492 glucose multiple interactions ISO RGD:733712 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF4 protein] more ... CTD PMID:29427785 , PMID:31022492 glutaraldehyde increases expression ISO RGD:733712 6480464 Glutaral results in increased expression of ATF4 mRNA CTD PMID:28236482 glutathione multiple interactions ISO RGD:733712 6480464 Glutathione inhibits the reaction [1 more ... CTD PMID:24515801 , PMID:30266318 gold atom multiple interactions ISO RGD:733712 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of ATF4 mRNA CTD PMID:28433809 gold(0) multiple interactions ISO RGD:733712 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of ATF4 mRNA CTD PMID:28433809 GSK2656157 multiple interactions ISO RGD:733713 6480464 GSK2656157 inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] CTD PMID:30602124 helenalin increases expression ISO RGD:733712 6480464 helenalin results in increased expression of ATF4 protein CTD PMID:23123298 hexadecanoic acid increases expression ISO RGD:733713 6480464 Palmitic Acid results in increased expression of ATF4 protein CTD PMID:30208301 hydralazine multiple interactions ISO RGD:733713 6480464 Hydralazine inhibits the reaction [Ethanol results in increased expression of ATF4 mRNA] CTD PMID:28119953 hydrogen peroxide decreases expression ISO RGD:733712 6480464 Hydrogen Peroxide results in decreased expression of ATF4 mRNA CTD PMID:12419474 hydroquinone increases expression ISO RGD:733712 6480464 hydroquinone results in increased expression of ATF4 mRNA CTD PMID:15452088 ibuprofen affects activity ISO RGD:733712 6480464 Ibuprofen affects the activity of ATF4 protein CTD PMID:25596134 ifosfamide affects activity ISO RGD:733712 6480464 Ifosfamide affects the activity of ATF4 protein CTD PMID:25596134 ionomycin multiple interactions ISO RGD:733712 6480464 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA], [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA CTD PMID:15477007 ivermectin increases expression ISO RGD:733713 6480464 Ivermectin results in increased expression of ATF4 mRNA CTD PMID:28942281 ivermectin increases expression ISO RGD:733712 6480464 Ivermectin results in increased expression of ATF4 mRNA CTD PMID:28942281 KN-93 multiple interactions EXP 6480464 KN 93 inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:29883672 L-1,4-dithiothreitol increases expression ISO RGD:733713 6480464 Dithiothreitol results in increased expression of ATF4 mRNA CTD PMID:27226639 L-1,4-dithiothreitol increases expression ISO RGD:733712 6480464 Dithiothreitol results in increased expression of ATF4 mRNA CTD PMID:27226639 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of ATF4 protein CTD PMID:22811615 lead diacetate decreases expression ISO RGD:733713 6480464 lead acetate results in decreased expression of ATF4 mRNA CTD PMID:24260418 lead(II) chloride multiple interactions ISO RGD:733712 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of ATF4 mRNA CTD PMID:18654764 leflunomide increases expression ISO RGD:733712 6480464 leflunomide results in increased expression of ATF4 protein CTD PMID:28988120 , PMID:29427785 leflunomide multiple interactions ISO RGD:733712 6480464 4-phenylbutyric acid inhibits the reaction [leflunomide results in increased expression of ATF4 protein] more ... CTD PMID:28988120 , PMID:29427785 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of ATF4 mRNA CTD PMID:24136188 linsidomine increases expression ISO RGD:733712 6480464 linsidomine results in increased expression of ATF4 mRNA CTD PMID:21703327 lipoic acid multiple interactions ISO RGD:733713 6480464 Thioctic Acid inhibits the reaction [arsenic trioxide results in increased expression of ATF4 mRNA], Thioctic Acid inhibits the reaction [arsenic trioxide results in increased expression of ATF4 protein] CTD PMID:23892647 lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:30605698 lipopolysaccharide increases expression ISO RGD:733712 6480464 Lipopolysaccharides results in increased expression of ATF4 protein CTD PMID:19675143 lipopolysaccharide multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of ATF4 mRNA] more ... CTD PMID:28844859 lithium chloride increases expression ISO RGD:733712 6480464 Lithium Chloride results in increased expression of ATF4 mRNA CTD PMID:15711924 LY294002 multiple interactions ISO RGD:733712 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of ATF4] more ... CTD PMID:24057571 manganese(II) chloride multiple interactions EXP 6480464 manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA], SNCA protein promotes the reaction [manganese chloride results in increased expression of ATF4 mRNA] CTD PMID:23934647 , PMID:23948121 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of ATF4 mRNA, manganese chloride results in increased expression of ATF4 protein CTD PMID:23934647 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [sodium arsenite results in increased expression of ATF4 protein] CTD PMID:17645694 metformin affects activity EXP 6480464 Metformin affects the activity of ATF4 protein CTD PMID:25596134 methamphetamine multiple interactions ISO RGD:733712 6480464 ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein] more ... CTD PMID:27323860 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of ATF4 mRNA, Methamphetamine results in increased expression of ATF4 protein CTD PMID:19564919 methamphetamine multiple interactions EXP 6480464 SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 mRNA], SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 protein] CTD PMID:19564919 methamphetamine increases expression ISO RGD:733712 6480464 Methamphetamine results in increased expression of ATF4 protein CTD PMID:27323860 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of ATF4 mRNA CTD PMID:17450226 methylmercury chloride increases expression ISO RGD:733712 6480464 methylmercuric chloride results in increased expression of ATF4 mRNA CTD PMID:28001369 methylmercury chloride increases expression ISO RGD:733713 6480464 methylmercuric chloride results in increased expression of ATF4 protein CTD PMID:31330229 methylmercury chloride multiple interactions ISO RGD:733713 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ATF4 protein], AKT1 protein mutant form inhibits the reaction [methylmercuric chloride results in increased expression of ATF4 protein] CTD PMID:31330229 mitomycin C increases expression ISO RGD:733712 6480464 Mitomycin results in increased expression of ATF4 mRNA CTD PMID:12760830 mitomycin C decreases expression ISO RGD:733713 6480464 Mitomycin results in decreased expression of ATF4 mRNA CTD PMID:25270620 MK-2206 multiple interactions ISO RGD:733712 6480464 MK 2206 inhibits the reaction [Cadmium Chloride results in increased expression of ATF4] CTD PMID:24057571 N-acetyl-L-cysteine multiple interactions ISO RGD:733712 6480464 Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of ATF4 protein] more ... CTD PMID:15788408 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF4 protein], Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ATF4 protein] CTD PMID:24291486 , PMID:27484784 N-acetyl-L-cysteine decreases expression EXP 6480464 Acetylcysteine results in decreased expression of ATF4 protein CTD PMID:27484784 N-acetyl-L-cysteine multiple interactions ISO RGD:733713 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of ATF4 protein], Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ATF4 protein] CTD PMID:25451595 , PMID:31330229 N-acetyl-L-cysteine increases expression ISO RGD:733712 6480464 Acetylcysteine results in increased expression of ATF4 protein CTD PMID:19722195 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:733712 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein CTD PMID:14604972 , PMID:17912641 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:733713 6480464 Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein] CTD PMID:23593480 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:733713 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein CTD PMID:23593480 N-hexadecanoylsphingosine increases expression ISO RGD:733713 6480464 N-palmitoylsphingosine results in increased expression of ATF4 mRNA CTD PMID:28223344 N-hexadecanoylsphingosine multiple interactions ISO RGD:733713 6480464 tauroursodeoxycholic acid inhibits the reaction [N-palmitoylsphingosine results in increased expression of ATF4 mRNA] CTD PMID:28223344 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ATF4 mRNA, 1-Methyl-4-phenylpyridinium results in increased expression of ATF4 protein CTD PMID:12486162 , PMID:28801915 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:733712 6480464 ATF4 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SLC30A10 mRNA] CTD PMID:28688763 N-methyl-4-phenylpyridinium increases expression ISO RGD:733712 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ATF4 mRNA, 1-Methyl-4-phenylpyridinium results in increased expression of ATF4 protein CTD PMID:24810058 more ... N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATF4 mRNA CTD PMID:17602206 nefazodone multiple interactions ISO RGD:733712 6480464 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3, 4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of ATF4 protein] CTD PMID:27613715 nefazodone increases expression ISO RGD:733712 6480464 nefazodone results in increased expression of ATF4 protein CTD PMID:27613715 nelfinavir increases expression ISO RGD:733712 6480464 Nelfinavir results in increased expression of ATF4 protein CTD PMID:22935518 Niclosamide increases expression ISO RGD:733712 6480464 Niclosamide results in increased expression of ATF4 mRNA, Niclosamide results in increased expression of ATF4 protein CTD PMID:26917416 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of ATF4 mRNA CTD PMID:24136188 Nodularin increases expression ISO RGD:733712 6480464 nodularin results in increased expression of ATF4 mRNA CTD PMID:27061667 Nonidet P-40 increases expression ISO RGD:733712 6480464 Nonidet P-40 results in increased expression of ATF4 mRNA CTD PMID:26552463 ochratoxin A decreases expression ISO RGD:733712 6480464 ochratoxin A results in decreased expression of ATF4 mRNA CTD PMID:30559759 orlistat increases expression ISO RGD:733712 6480464 orlistat results in increased expression of ATF4 mRNA CTD PMID:17283163 oxidopamine increases expression EXP 6480464 Oxidopamine results in increased expression of ATF4 mRNA, Oxidopamine results in increased expression of ATF4 protein CTD PMID:12486162 oxycodone increases expression ISO RGD:733712 6480464 Oxycodone results in increased expression of ATF4 protein CTD PMID:26377394 oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of ATF4 protein CTD PMID:26377394 p-tert-Amylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of ATF4 mRNA CTD PMID:17011747 p-tert-Amylphenol decreases expression EXP 6480464 4-tert-octylphenol results in decreased expression of ATF4 mRNA CTD PMID:17011747 paracetamol decreases expression ISO RGD:733713 6480464 Acetaminophen results in decreased expression of ATF4 mRNA CTD PMID:17585979 paracetamol increases expression ISO RGD:733712 6480464 Acetaminophen results in increased expression of ATF4 mRNA CTD PMID:21420995 , PMID:29067470 paracetamol affects expression ISO RGD:733713 6480464 Acetaminophen affects the expression of ATF4 mRNA CTD PMID:15606129 , PMID:17562736 paracetamol increases expression ISO RGD:733713 6480464 Acetaminophen results in increased expression of ATF4 mRNA CTD PMID:11264010 paracetamol multiple interactions ISO RGD:733713 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ATF4 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ATF4 mRNA] CTD PMID:17585979 paraquat increases expression ISO RGD:733713 6480464 Paraquat results in increased expression of ATF4 mRNA CTD PMID:21371552 perfluorooctane-1-sulfonic acid affects expression ISO RGD:733713 6480464 perfluorooctane sulfonic acid affects the expression of ATF4 mRNA CTD PMID:19429403 perfluorooctanoic acid affects expression ISO RGD:733713 6480464 perfluorooctanoic acid affects the expression of ATF4 mRNA CTD PMID:19429403 phenobarbital affects expression ISO RGD:733712 6480464 Phenobarbital affects the expression of ATF4 mRNA CTD PMID:19159669 phenobarbital decreases expression ISO RGD:733713 6480464 Phenobarbital results in decreased expression of ATF4 mRNA CTD PMID:23091169 PhIP increases expression ISO RGD:733712 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of ATF4 mRNA CTD PMID:20702593 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:733712 6480464 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA], [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA CTD PMID:15477007 pirinixic acid increases expression ISO RGD:733713 6480464 pirinixic acid results in increased expression of ATF4 mRNA CTD PMID:16985257 piroxicam decreases expression ISO RGD:733712 6480464 Piroxicam results in decreased expression of ATF4 mRNA CTD PMID:21858171 potassium chromate increases expression ISO RGD:733712 6480464 potassium chromate(VI) results in increased expression of ATF4 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:733712 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of ATF4 mRNA CTD PMID:22079256 progesterone increases expression ISO RGD:733712 6480464 Progesterone results in increased expression of ATF4 mRNA CTD PMID:18037150 pyrazinecarboxamide increases expression ISO RGD:733712 6480464 Pyrazinamide results in increased expression of ATF4 mRNA, Pyrazinamide results in increased expression of ATF4 protein CTD PMID:28063906 pyrazinecarboxamide increases expression EXP 6480464 Pyrazinamide results in increased expression of ATF4 protein CTD PMID:28063906 pyrazinecarboxamide multiple interactions ISO RGD:733712 6480464 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased expression of ATF4 protein] CTD PMID:28063906 pyrazinecarboxamide multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased expression of ATF4 protein] CTD PMID:28063906 pyrrolidine dithiocarbamate multiple interactions ISO RGD:733712 6480464 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA] CTD PMID:15477007 pyrrolidine dithiocarbamate multiple interactions EXP 6480464 [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA, pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA] CTD PMID:20920558 quercetin multiple interactions ISO RGD:733712 6480464 Quercetin inhibits the reaction [Tunicamycin results in increased expression of ATF4 protein] more ... CTD PMID:22115781 , PMID:25611565 quercetin increases expression ISO RGD:733712 6480464 Quercetin results in increased expression of ATF4 protein CTD PMID:25611565 rac-lactic acid increases expression ISO RGD:733712 6480464 Lactic Acid results in increased expression of ATF4 mRNA CTD PMID:30851411 reactive oxygen species multiple interactions ISO RGD:733713 6480464 [arsenic trioxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of ATF4 protein CTD PMID:23892647 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Dietary Fats results in increased expression of ATF4 protein] CTD PMID:26055348 resveratrol multiple interactions ISO RGD:733712 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of ATF4 protein] CTD PMID:24224909 rifampicin multiple interactions EXP 6480464 ATF4 mutant form inhibits the reaction [Rifampin results in increased expression of HSPA5 protein] CTD PMID:24638036 rifampicin multiple interactions ISO RGD:733712 6480464 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 mRNA], 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 protein] CTD PMID:27470132 rifampicin increases expression ISO RGD:733712 6480464 Rifampin results in increased expression of ATF4 mRNA, Rifampin results in increased expression of ATF4 protein CTD PMID:27470132 rifampicin increases expression EXP 6480464 Rifampin results in increased expression of ATF4 protein CTD PMID:24638036 rotenone increases expression ISO RGD:733712 6480464 Rotenone results in increased expression of ATF4 mRNA, Rotenone results in increased expression of ATF4 protein CTD PMID:19233273 more ... rotenone decreases expression ISO RGD:733712 6480464 Rotenone results in decreased expression of ATF4 mRNA CTD PMID:29955902 rotenone increases phosphorylation ISO RGD:733712 6480464 Rotenone results in increased phosphorylation of ATF4 protein CTD PMID:26864693 rotenone multiple interactions ISO RGD:733712 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of ATF4 protein], MIR384 mRNA promotes the reaction [Rotenone results in increased phosphorylation of ATF4 protein] CTD PMID:26864693 , PMID:30141137 rotenone increases expression ISO RGD:733713 6480464 Rotenone results in increased expression of ATF4 mRNA CTD PMID:23186747 rotenone increases expression EXP 6480464 Rotenone results in increased expression of ATF4 protein CTD PMID:12486162 salubrinal multiple interactions ISO RGD:733712 6480464 [salubrinal co-treated with EPO protein] results in decreased expression of ATF4 protein more ... CTD PMID:23690448 more ... salubrinal multiple interactions EXP 6480464 salubrinal promotes the reaction [Thapsigargin results in increased expression of ATF4 protein], salubrinal promotes the reaction [Tunicamycin results in increased expression of ATF4 protein] CTD PMID:28844859 salubrinal multiple interactions ISO RGD:733713 6480464 salubrinal promotes the reaction [Cisplatin results in increased expression of ATF4 protein] CTD PMID:21616140 salubrinal increases expression ISO RGD:733712 6480464 salubrinal results in increased expression of ATF4 protein CTD PMID:21809093 , PMID:23690448 SCH 23390 multiple interactions EXP 6480464 SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 mRNA], SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 protein] CTD PMID:19564919 selenium atom increases expression ISO RGD:733712 6480464 Selenium results in increased expression of ATF4 mRNA CTD PMID:19244175 sertraline increases expression ISO RGD:733712 6480464 Sertraline results in increased expression of ATF4 protein CTD PMID:24865413 sirolimus multiple interactions ISO RGD:733712 6480464 Sirolimus inhibits the reaction [Cadmium Chloride results in increased expression of ATF4] CTD PMID:24057571 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:29870746 sodium arsenate increases expression ISO RGD:733713 6480464 sodium arsenate analog results in increased expression of ATF4 mRNA CTD PMID:23221991 sodium arsenite increases response to substance ISO RGD:733712 6480464 ATF4 mutant form results in increased susceptibility to sodium arsenite CTD PMID:17938202 sodium arsenite multiple interactions ISO RGD:733712 6480464 [ATF4 mutant form results in increased susceptibility to sodium arsenite] which results in increased mutagenesis of HPRT1 gene more ... CTD PMID:15788408 , PMID:17938202 sodium arsenite affects response to substance ISO RGD:733713 6480464 ATF4 affects the susceptibility to sodium arsenite CTD PMID:17938202 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of ATF4 protein CTD PMID:17645694 , PMID:17681577 sodium arsenite increases expression ISO RGD:733713 6480464 sodium arsenite results in increased expression of ATF4 mRNA, sodium arsenite results in increased expression of ATF4 protein CTD PMID:12606582 more ... sodium arsenite multiple interactions EXP 6480464 Melatonin inhibits the reaction [sodium arsenite results in increased expression of ATF4 protein] CTD PMID:17645694 sodium arsenite multiple interactions ISO RGD:733713 6480464 [[sodium arsenite promotes the reaction [JUN protein binds to ATF4 protein]] which binds to APEX1 promoter] which results in increased expression of APEX1 mRNA more ... CTD PMID:16330322 , PMID:17938202 sodium arsenite increases expression ISO RGD:733712 6480464 sodium arsenite results in increased expression of ATF4 mRNA CTD PMID:12760830 sodium dichromate increases expression ISO RGD:733712 6480464 sodium bichromate results in increased expression of ATF4 mRNA CTD PMID:12760830 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of ATF4 mRNA CTD PMID:22561333 sodium dichromate increases expression ISO RGD:733713 6480464 sodium bichromate results in increased expression of ATF4 mRNA CTD PMID:22155349 sodium fluoride decreases expression EXP 6480464 Sodium Fluoride results in decreased expression of ATF4 mRNA CTD PMID:25132241 Soman increases expression EXP 6480464 Soman results in increased expression of ATF4 mRNA CTD PMID:19281266 sorafenib multiple interactions ISO RGD:733712 6480464 [[[sorafenib results in increased expression of ATF4 protein] which results in increased expression of DDIT4 protein] which results in decreased activity of MTOR protein] which results in decreased expression of BIRC5 protein more ... CTD PMID:21601561 sorafenib increases expression ISO RGD:733712 6480464 [sorafenib results in increased expression of ATF4 protein] which results in increased expression of DDIT3 mRNA more ... CTD PMID:21601561 streptozocin multiple interactions ISO RGD:733713 6480464 sulforafan inhibits the reaction [Streptozocin results in increased expression of ATF4 protein] CTD PMID:24967692 streptozocin multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased phosphorylation of ATF4 protein] CTD PMID:30980806 streptozocin increases phosphorylation EXP 6480464 Streptozocin results in increased phosphorylation of ATF4 protein CTD PMID:30980806 streptozocin increases expression ISO RGD:733713 6480464 Streptozocin results in increased expression of ATF4 protein CTD PMID:24967692 sulforaphane multiple interactions ISO RGD:733713 6480464 sulforafan inhibits the reaction [Streptozocin results in increased expression of ATF4 protein] CTD PMID:24967692 sulindac increases expression ISO RGD:733712 6480464 Sulindac results in increased expression of ATF4 mRNA CTD PMID:11906190 sunitinib increases expression ISO RGD:733712 6480464 Sunitinib results in increased expression of ATF4 mRNA CTD PMID:31533062 tacrolimus hydrate increases expression ISO RGD:733713 6480464 Tacrolimus results in increased expression of ATF4 mRNA CTD PMID:23958496 tamoxifen affects expression ISO RGD:733713 6480464 Tamoxifen affects the expression of ATF4 mRNA CTD PMID:17555576 tamoxifen increases expression ISO RGD:733713 6480464 Tamoxifen results in increased expression of ATF4 mRNA CTD PMID:19400957 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of ATF4 mRNA CTD PMID:19400957 tauroursodeoxycholic acid multiple interactions ISO RGD:733713 6480464 tauroursodeoxycholic acid inhibits the reaction [N-palmitoylsphingosine results in increased expression of ATF4 mRNA] CTD PMID:28223344 tauroursodeoxycholic acid decreases expression ISO RGD:733712 6480464 tauroursodeoxycholic acid results in decreased expression of ATF4 mRNA CTD PMID:24312631 tauroursodeoxycholic acid multiple interactions ISO RGD:733712 6480464 tauroursodeoxycholic acid inhibits the reaction [Quercetin results in increased expression of ATF4 protein] CTD PMID:25611565 tetrachloromethane increases expression ISO RGD:733713 6480464 Carbon Tetrachloride results in increased expression of ATF4 mRNA CTD PMID:25827057 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of ATF4 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ATF4 mRNA] CTD PMID:31150632 tetrachloromethane multiple interactions ISO RGD:733713 6480464 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Carbon Tetrachloride results in increased expression of ATF4 mRNA] CTD PMID:25827057 thapsigargin multiple interactions ISO RGD:733712 6480464 ATF4 mutant form inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 mRNA] more ... CTD PMID:16298333 , PMID:20022965 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of ATF4 protein CTD PMID:28844859 thapsigargin multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein], salubrinal promotes the reaction [Thapsigargin results in increased expression of ATF4 protein] CTD PMID:28844859 thapsigargin increases expression ISO RGD:733712 6480464 Thapsigargin results in increased expression of ATF4 mRNA, Thapsigargin results in increased expression of ATF4 protein CTD PMID:16298333 more ... thapsigargin increases activity ISO RGD:733712 6480464 Thapsigargin results in increased activity of ATF4 protein CTD PMID:23383089 thapsigargin multiple interactions ISO RGD:733713 6480464 ATF4 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form], EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of ATF4 mRNA] CTD PMID:24648495 , PMID:29109149 thapsigargin increases expression ISO RGD:733713 6480464 Thapsigargin results in increased expression of ATF4 mRNA, Thapsigargin results in increased expression of ATF4 protein CTD PMID:20589738 more ... thapsigargin decreases response to substance ISO RGD:733712 6480464 ATF4 results in decreased susceptibility to Thapsigargin CTD PMID:20022965 Tiron multiple interactions ISO RGD:733713 6480464 1 more ... CTD PMID:15509775 , PMID:23892647 Tiron multiple interactions ISO RGD:733712 6480464 1 more ... CTD PMID:15509775 titanium dioxide increases expression ISO RGD:733713 6480464 titanium dioxide results in increased expression of ATF4 mRNA CTD PMID:27760801 Tributyltin oxide increases expression ISO RGD:733713 6480464 bis(tri-n-butyltin)oxide results in increased expression of ATF4 mRNA CTD PMID:21601586 , PMID:22434021 Tributyltin oxide increases expression EXP 6480464 bis(tri-n-butyltin)oxide results in increased expression of ATF4 mRNA CTD PMID:17553608 , PMID:21601586 triclocarban increases expression ISO RGD:733712 6480464 triclocarban results in increased expression of ATF4 protein CTD PMID:30592132 trimethylamine N-oxide multiple interactions ISO RGD:733712 6480464 trimethyloxamine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of ATF4 protein] CTD PMID:25568320 Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of ATF4 mRNA CTD PMID:23639586 troglitazone decreases expression ISO RGD:733713 6480464 troglitazone results in decreased expression of ATF4 mRNA CTD PMID:28973697 tunicamycin multiple interactions ISO RGD:733713 6480464 1 more ... CTD PMID:22959925 more ... tunicamycin multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of ATF4 protein], salubrinal promotes the reaction [Tunicamycin results in increased expression of ATF4 protein] CTD PMID:28844859 tunicamycin multiple interactions ISO RGD:733712 6480464 ATF4 protein affects the reaction [[Tunicamycin co-treated with APP protein modified form] results in increased expression of PSEN1 mRNA], Quercetin inhibits the reaction [Tunicamycin results in increased expression of ATF4 protein] CTD PMID:22115781 tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of ATF4 mRNA, Tunicamycin results in increased expression of ATF4 protein CTD PMID:24291486 more ... tunicamycin increases expression ISO RGD:733712 6480464 Tunicamycin results in increased expression of ATF4 mRNA, Tunicamycin results in increased expression of ATF4 protein CTD PMID:14604972 more ... tunicamycin increases phosphorylation ISO RGD:733712 6480464 Tunicamycin results in increased phosphorylation of ATF4 protein CTD PMID:22959463 tunicamycin increases expression ISO RGD:733713 6480464 Tunicamycin results in increased expression of ATF4 mRNA, Tunicamycin results in increased expression of ATF4 protein CTD PMID:22001960 more ... urethane increases expression ISO RGD:733712 6480464 Urethane results in increased expression of ATF4 mRNA CTD PMID:28818685 ursodeoxycholic acid decreases expression ISO RGD:733712 6480464 Ursodeoxycholic Acid results in decreased expression of ATF4 mRNA CTD PMID:24312631 usnic acid multiple interactions ISO RGD:733712 6480464 2-aminoethoxydiphenyl borate inhibits the reaction [usnic acid results in increased expression of ATF4 protein] CTD PMID:25870318 usnic acid increases expression ISO RGD:733712 6480464 usnic acid results in increased expression of ATF4 protein CTD PMID:25870318 valproic acid decreases expression ISO RGD:733713 6480464 Valproic Acid results in decreased expression of ATF4 mRNA CTD PMID:20546886 withaferin A increases expression ISO RGD:733712 6480464 withaferin A results in increased expression of ATF4 protein CTD PMID:21266191 withaferin A multiple interactions ISO RGD:733712 6480464 Acetylcysteine inhibits the reaction [withaferin A results in increased expression of ATF4 protein] CTD PMID:21266191 zinc atom multiple interactions ISO RGD:733712 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of ATF4 mRNA CTD PMID:18593933 zinc dichloride decreases expression ISO RGD:733712 6480464 zinc chloride results in decreased expression of ATF4 mRNA CTD PMID:18947441 zinc(0) multiple interactions ISO RGD:733712 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of ATF4 mRNA CTD PMID:18593933 zoledronic acid decreases expression ISO RGD:733712 6480464 zoledronic acid results in decreased expression of ATF4 mRNA CTD PMID:24714768
Gene-Chemical Interaction Annotations
