![]()
Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | genetic disease | | ISO | RGD:1313737 | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | |
|
![]()
Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | genetic disease | | ISO | RGD:1313737 | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | |
|
|
|
|
|
|
|
|
|
|
|
# | Reference Title | Reference Citation |
1. | Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis. | Duda DG, etal., Br J Cancer. 2002 Feb 1;86(3):490-6. doi: 10.1038/sj.bjc.6600067. |
2. | The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites. | Duman JG, etal., J Neurosci. 2013 Apr 17;33(16):6964-78. doi: 10.1523/JNEUROSCI.3978-12.2013. |
3. | Brain-specific angiogenesis inhibitor 1 expression is inversely correlated with vascularity and distant metastasis of colorectal cancer. | Fukushima Y, etal., Int J Oncol. 1998 Nov;13(5):967-70. |
4. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
5. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
6. | Brain-specific angiogenesis inhibitor 1 is a putative factor for inhibition of neovascular formation in renal cell carcinoma. | Izutsu T, etal., J Urol. 2011 Jun;185(6):2353-8. doi: 10.1016/j.juro.2011.02.019. Epub 2011 Apr 21. |
7. | Antiangiogenic activity of BAI1 in vivo: implications for gene therapy of human glioblastomas. | Kang X, etal., Cancer Gene Ther. 2006 Apr;13(4):385-92. doi: 10.1038/sj.cgt.7700898. |
8. | Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression. | Kaur B, etal., Am J Pathol. 2003 Jan;162(1):19-27. doi: 10.1016/S0002-9440(10)63794-7. |
9. | Comparative study of angiostatic and anti-invasive gene expressions as prognostic factors in gastric cancer. | Lee JH, etal., Int J Oncol. 2001 Feb;18(2):355-61. |
10. | Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies. | Meisen WH, etal., Mol Cancer Ther. 2015 Jan;14(1):307-14. doi: 10.1158/1535-7163.MCT-14-0659. Epub 2014 Nov 5. |
11. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
12. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
13. | GOA pipeline | RGD automated data pipeline |
14. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
15. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
16. | Expression of brain-specific angiogenesis inhibitor 1 is inversely correlated with pathological grade, angiogenesis and peritumoral brain edema in human astrocytomas. | Wang W, etal., Oncol Lett. 2013 May;5(5):1513-1518. doi: 10.3892/ol.2013.1250. Epub 2013 Mar 12. |
PMID:8889548 | PMID:15782143 | PMID:17960134 | PMID:19176395 | PMID:20888903 | PMID:21245295 | PMID:22330140 | PMID:23615608 | PMID:23782696 | PMID:24509909 | PMID:24613359 | PMID:25751059 |
PMID:26838550 |
Adgrb1 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ADGRB1 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Adgrb1 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Adgrb1 (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ADGRB1 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ADGRB1 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LOC101964702 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ADGRB1 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LOC103237529 (Chlorocebus sabaeus - green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Adgrb1 (Heterocephalus glaber - naked mole-rat) |
|
.
Variants in Adgrb1
206 total Variants ![]() |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
RefSeq Transcripts | NM_001170597 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_039079531 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039079532 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039079533 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039079534 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039079535 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039079536 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039079537 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_005486670 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | BF417969 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
CB581992 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CB738223 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JACYVU010000185 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | NM_001170597 ⟹ NP_001164068 | ||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_039079531 ⟹ XP_038935459 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_039079532 ⟹ XP_038935460 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_039079533 ⟹ XP_038935461 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_039079534 ⟹ XP_038935462 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_039079535 ⟹ XP_038935463 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_039079536 ⟹ XP_038935464 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_039079537 ⟹ XP_038935465 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XR_005486670 | ||||||||
RefSeq Status: | |||||||||
Type: | NON-CODING | ||||||||
Position: |
|
Protein RefSeqs | NP_001164068 | (Get FASTA) | NCBI Sequence Viewer |
XP_038935459 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038935460 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038935461 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038935462 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038935463 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038935464 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038935465 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | C0HL12 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001164068 ⟸ NM_001170597 |
- Peptide Label: | precursor |
- UniProtKB: | C0HL12 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_038935465 ⟸ XM_039079537 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_038935464 ⟸ XM_039079536 |
- Peptide Label: | isoform X6 |
RefSeq Acc Id: | XP_038935459 ⟸ XM_039079531 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038935461 ⟸ XM_039079533 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | XP_038935460 ⟸ XM_039079532 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A8I5Y6L4 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038935462 ⟸ XM_039079534 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_038935463 ⟸ XM_039079535 |
- Peptide Label: | isoform X5 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-C0HL12-F1-model_v2 | AlphaFold | C0HL12 | 1-1577 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1305608 | AgrOrtholog |
BioCyc Gene | G2FUF-33038 | BioCyc |
Ensembl Genes | ENSRNOG00000029450 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000077654 | ENTREZGENE |
ENSRNOP00000077654.1 | UniProtKB/TrEMBL | |
ENSRNOP00000083996.1 | UniProtKB/TrEMBL | |
ENSRNOP00000085291 | ENTREZGENE | |
ENSRNOP00000085291.1 | UniProtKB/TrEMBL | |
ENSRNOP00000096011.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000015578 | ENTREZGENE |
ENSRNOT00000015578.9 | UniProtKB/TrEMBL | |
ENSRNOT00000076127 | ENTREZGENE | |
ENSRNOT00000076127.3 | UniProtKB/TrEMBL | |
ENSRNOT00000076380 | ENTREZGENE | |
ENSRNOT00000076380.2 | UniProtKB/TrEMBL | |
ENSRNOT00000076800.3 | UniProtKB/TrEMBL | |
Gene3D-CATH | 1.25.40.610 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
2.20.100.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
2.60.220.50 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
4.10.1240.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Rhodopsin 7-helix transmembrane proteins | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
InterPro | AGRB_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
GAIN_dom_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GAIN_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GPCR_2-like | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GPCR_2_brain_angio_inhib | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GPCR_2_extracell_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GPCR_2_extracellular_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GPCR_2_secretin-like | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GPS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
TSP1_rpt | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
TSP1_rpt_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:362931 | UniProtKB/Swiss-Prot |
NCBI Gene | 362931 | ENTREZGENE |
PANTHER | ADHESION G PROTEIN-COUPLED RECEPTOR B1 | UniProtKB/Swiss-Prot |
ADHESION G PROTEIN-COUPLED RECEPTOR B1 | UniProtKB/TrEMBL | |
ADHESION G PROTEIN-COUPLED RECEPTOR B1 | UniProtKB/TrEMBL | |
ADHESION G-PROTEIN COUPLED RECEPTOR | UniProtKB/TrEMBL | |
PROPERDIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | 7tm_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
AGRB_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GAIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GPS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
HRM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
TSP_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Adgrb1 | PhenoGen |
PRINTS | BAIPRECURSOR | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
GPCRSECRETIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
TSP1REPEAT | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PROSITE | G_PROTEIN_RECEP_F2_3 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
G_PROTEIN_RECEP_F2_4 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
GPS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PROKAR_LIPOPROTEIN | UniProtKB/TrEMBL | |
TSP1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SMART | GPS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
HormR | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
TSP1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | Formin homology 2 domain (FH2 domain) | UniProtKB/TrEMBL |
SSF82895 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A8I5Y6L4 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I5ZX20_RAT | UniProtKB/TrEMBL | |
A0A8I5ZZU7_RAT | UniProtKB/TrEMBL | |
A0A8I6ASL1_RAT | UniProtKB/TrEMBL | |
AGRB1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2015-03-16 | Adgrb1 | adhesion G protein-coupled receptor B1 | Bai1 | brain-specific angiogenesis inhibitor 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-30 | Bai1 | brain-specific angiogenesis inhibitor 1 | Bai1_predicted | brain-specific angiogenesis inhibitor 1 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Bai1_predicted | brain-specific angiogenesis inhibitor 1 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |