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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of KIFC2 mRNA] | CTD | PMID:31150632 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | decreases expression | ISO | RGD:1332388 | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:15329391 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1332388 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KIFC2 mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | ISO | RGD:1332388 | 6480464 | Estradiol results in decreased expression of KIFC2 mRNA | CTD | PMID:25575267 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1332388 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KIFC2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1332388 | 6480464 | Tetrachlorodibenzodioxin affects the expression of KIFC2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KIFC2 mRNA | CTD | PMID:21215274 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | RGD:1332388 | 6480464 | tetrabromobisphenol A results in decreased expression of KIFC2 mRNA | CTD | PMID:25172293 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:1332388 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of KIFC2 mRNA | CTD | PMID:26251327 | 4,4'-sulfonyldiphenol | increases methylation | ISO | RGD:1332388 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased methylation of KIFC2 exon | CTD | PMID:33297965 | 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid | decreases expression | ISO | RGD:1352702 | 6480464 | Am 580 results in decreased expression of KIFC2 mRNA | CTD | PMID:16982809 | arsenous acid | decreases expression | ISO | RGD:1352702 | 6480464 | Arsenic Trioxide results in decreased expression of KIFC2 mRNA | CTD | PMID:22521957 | benzo[a]pyrene | decreases expression | ISO | RGD:1352702 | 6480464 | Benzo(a)pyrene results in decreased expression of KIFC2 mRNA | CTD | PMID:20106945 | benzo[a]pyrene | decreases methylation | ISO | RGD:1352702 | 6480464 | Benzo(a)pyrene results in decreased methylation of KIFC2 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | ISO | RGD:1332388 | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of KIFC2 mRNA] | CTD | PMID:22228805 | bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:1332388 | 6480464 | Mustard Gas results in increased expression of KIFC2 mRNA | CTD | PMID:15674844 | bisphenol A | decreases expression | ISO | RGD:1332388 | 6480464 | bisphenol A results in decreased expression of KIFC2 mRNA | CTD | PMID:26063408 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of KIFC2 mRNA | CTD | PMID:30816183, PMID:32528016 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of KIFC2 mRNA | CTD | PMID:25181051 | butanal | decreases expression | ISO | RGD:1352702 | 6480464 | butyraldehyde results in decreased expression of KIFC2 mRNA | CTD | PMID:26079696 | carbon nanotube | decreases expression | ISO | RGD:1332388 | 6480464 | Nanotubes more ... | CTD | PMID:25554681, PMID:25620056 | clofibrate | decreases expression | ISO | RGD:1332388 | 6480464 | Clofibrate results in decreased expression of KIFC2 mRNA | CTD | PMID:23811191 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of KIFC2 mRNA | CTD | PMID:26577399 | cyclosporin A | decreases expression | ISO | RGD:1352702 | 6480464 | Cyclosporine results in decreased expression of KIFC2 mRNA | CTD | PMID:20106945 | diarsenic trioxide | decreases expression | ISO | RGD:1352702 | 6480464 | Arsenic Trioxide results in decreased expression of KIFC2 mRNA | CTD | PMID:22521957 | dichloroacetic acid | decreases expression | ISO | RGD:1332388 | 6480464 | Dichloroacetic Acid results in decreased expression of KIFC2 mRNA | CTD | PMID:28962523 | dorsomorphin | multiple interactions | ISO | RGD:1352702 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIFC2 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | RGD:1352702 | 6480464 | Doxorubicin results in decreased expression of KIFC2 mRNA | CTD | PMID:29803840 | entinostat | increases expression | ISO | RGD:1352702 | 6480464 | entinostat results in increased expression of KIFC2 mRNA | CTD | PMID:27188386 | ethanol | increases expression | ISO | RGD:1332388 | 6480464 | Ethanol results in increased expression of KIFC2 mRNA | CTD | PMID:30319688 | ethanol | affects splicing | ISO | RGD:1332388 | 6480464 | Ethanol affects the splicing of KIFC2 mRNA | CTD | PMID:30319688 | folic acid | increases expression | ISO | RGD:1332388 | 6480464 | Folic Acid results in increased expression of KIFC2 mRNA | CTD | PMID:25629700 | furan | decreases expression | ISO | RGD:1332388 | 6480464 | furan results in decreased expression of KIFC2 mRNA | CTD | PMID:24183702 | lamivudine | multiple interactions | ISO | RGD:1332388 | 6480464 | [Zidovudine co-treated with Lamivudine] results in decreased expression of KIFC2 mRNA | CTD | PMID:16931933 | lead(0) | affects expression | ISO | RGD:1352702 | 6480464 | Lead affects the expression of KIFC2 mRNA | CTD | PMID:28903495 | lead(2+) | affects expression | ISO | RGD:1352702 | 6480464 | Lead affects the expression of KIFC2 mRNA | CTD | PMID:28903495 | paracetamol | decreases expression | ISO | RGD:1332388 | 6480464 | Acetaminophen results in decreased expression of KIFC2 mRNA | CTD | PMID:17585979 | paracetamol | affects expression | ISO | RGD:1332388 | 6480464 | Acetaminophen affects the expression of KIFC2 mRNA | CTD | PMID:17562736 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of KIFC2 mRNA | CTD | PMID:32680482 | phenobarbital | affects expression | ISO | RGD:1332388 | 6480464 | Phenobarbital affects the expression of KIFC2 mRNA | CTD | PMID:23091169 | quercetin | increases expression | ISO | RGD:1352702 | 6480464 | Quercetin results in increased expression of KIFC2 mRNA | CTD | PMID:21632981 | SB 431542 | multiple interactions | ISO | RGD:1352702 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIFC2 mRNA | CTD | PMID:27188386 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of KIFC2 mRNA | CTD | PMID:19281266 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of KIFC2 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of KIFC2 mRNA] | CTD | PMID:31150632 | tetraphene | affects expression | ISO | RGD:1332388 | 6480464 | benz(a)anthracene affects the expression of KIFC2 mRNA | CTD | PMID:26377693 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of KIFC2 mRNA | CTD | PMID:23411599 | trichloroethene | decreases expression | ISO | RGD:1332388 | 6480464 | Trichloroethylene results in decreased expression of KIFC2 mRNA | CTD | PMID:15363585 | triptonide | increases expression | ISO | RGD:1332388 | 6480464 | triptonide results in increased expression of KIFC2 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | RGD:1332388 | 6480464 | Valproic Acid affects the expression of KIFC2 mRNA | CTD | PMID:17292431 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of KIFC2 mRNA | CTD | PMID:29427782 | valproic acid | multiple interactions | ISO | RGD:1352702 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIFC2 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | RGD:1352702 | 6480464 | Valproic Acid results in increased expression of KIFC2 mRNA | CTD | PMID:19101580 more ... | valproic acid | affects expression | ISO | RGD:1352702 | 6480464 | Valproic Acid affects the expression of KIFC2 mRNA | CTD | PMID:25979313 | valproic acid | increases methylation | ISO | RGD:1352702 | 6480464 | Valproic Acid results in increased methylation of KIFC2 gene | CTD | PMID:29154799 | zidovudine | multiple interactions | ISO | RGD:1332388 | 6480464 | [Zidovudine co-treated with Lamivudine] results in decreased expression of KIFC2 mRNA | CTD | PMID:16931933 | |