Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Nicotine results in increased expression of KRT80 mRNA | CTD | PMID:23825647 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of KRT80 mRNA | CTD | PMID:30723492 | 17beta-estradiol | decreases expression | ISO | Krt80 (Mus musculus) | 6480464 | Estradiol results in decreased expression of KRT80 mRNA | CTD | PMID:19484750 | 17beta-estradiol | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Estradiol results in increased expression of KRT80 mRNA | CTD | PMID:31614463 | 17beta-estradiol | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of KRT80 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Krt80 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KRT80 mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KRT80 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KRT80 mRNA | CTD | PMID:23152189 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Krt80 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of KRT80 mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2-hydroxypropanoic acid | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KRT80 mRNA | CTD | PMID:30851411 | 4,4'-sulfonyldiphenol | increases expression | ISO | Krt80 (Mus musculus) | 6480464 | bisphenol S results in increased expression of KRT80 mRNA | CTD | PMID:30951980 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Krt80 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of KRT80 mRNA | CTD | PMID:28973697 | 7,12-dimethyltetraphene | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | 9 more ... | CTD | PMID:21527772 | actinomycin D | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Dactinomycin results in increased expression of KRT80 mRNA | CTD | PMID:21527772 | aflatoxin B1 | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of KRT80 mRNA and Aflatoxin B1 results in increased expression of KRT80 protein | CTD | PMID:21527772 and PMID:22100608 | Archazolid B | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | archazolid B results in decreased expression of KRT80 mRNA | CTD | PMID:25218289 | aristolochic acid A | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of KRT80 mRNA and aristolochic acid I results in increased expression of KRT80 protein | CTD | PMID:33212167 | arsane | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of KRT80 mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of KRT80 mRNA | CTD | PMID:32525701 | benzo[a]pyrene | increases expression | ISO | Krt80 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of KRT80 mRNA | CTD | PMID:22610609 | benzo[a]pyrene | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of KRT80 mRNA | CTD | PMID:32234424 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | benzo[b]fluoranthene | increases expression | ISO | Krt80 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of KRT80 mRNA | CTD | PMID:26377693 | bis(2-chloroethyl) sulfide | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Mustard Gas results in increased expression of KRT80 mRNA | CTD | PMID:25102026 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of KRT80 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Krt80 (Mus musculus) | 6480464 | bisphenol A results in increased expression of KRT80 mRNA | CTD | PMID:32156529 | bisphenol A | decreases methylation | ISO | Krt80 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of KRT80 promoter | CTD | PMID:27312807 | bisphenol F | increases expression | ISO | Krt80 (Mus musculus) | 6480464 | bisphenol F results in increased expression of KRT80 mRNA | CTD | PMID:30951980 | butanal | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of KRT80 mRNA | CTD | PMID:26079696 | cadmium atom | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Cadmium results in increased expression of KRT80 mRNA | CTD | PMID:24376830 | calcitriol | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of KRT80 mRNA | CTD | PMID:21592394 | calcitriol | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of KRT80 mRNA | CTD | PMID:21592394 | carbon nanotube | increases expression | ISO | Krt80 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cisplatin | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of KRT80 mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of KRT80 mRNA | CTD | PMID:27392435 | copper atom | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of KRT80 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of KRT80 mRNA | CTD | PMID:20971185 | coumestrol | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of KRT80 mRNA | CTD | PMID:19167446 | coumestrol | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KRT80 mRNA | CTD | PMID:19167446 | cyclophosphamide | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Cyclophosphamide results in increased expression of KRT80 mRNA | CTD | PMID:21527772 | cyclosporin A | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of KRT80 mRNA | CTD | PMID:25562108 | cyclosporin A | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of KRT80 mRNA | CTD | PMID:27989131 | endosulfan | affects expression | EXP | | 6480464 | Endosulfan affects the expression of KRT80 mRNA | CTD | PMID:29391264 | Enterolactone | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KRT80 mRNA | CTD | PMID:19167446 | epoxiconazole | decreases expression | ISO | Krt80 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of KRT80 mRNA | CTD | PMID:35436446 | ethanol | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of KRT80 mRNA | CTD | PMID:29432896 | ethylparaben | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of KRT80 mRNA | CTD | PMID:37690743 | etoposide | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Etoposide results in increased expression of KRT80 mRNA | CTD | PMID:21527772 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of KRT80 mRNA | CTD | PMID:33387578 | hexadecanoic acid | decreases phosphorylation | ISO | KRT80 (Homo sapiens) | 6480464 | Palmitic Acid results in decreased phosphorylation of KRT80 protein | CTD | PMID:28073184 | hydroquinone | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | hydroquinone results in increased expression of KRT80 mRNA | CTD | PMID:31256213 | lipopolysaccharide | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of KRT80 mRNA | CTD | PMID:35811015 | metformin | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Metformin results in increased expression of KRT80 mRNA | CTD | PMID:21527772 | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of KRT80 mRNA | CTD | PMID:28341135 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of KRT80 gene | CTD | PMID:35440735 | methyl methanesulfonate | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of KRT80 mRNA | CTD | PMID:21527772 | N-nitrosodiethylamine | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Diethylnitrosamine results in increased expression of KRT80 mRNA | CTD | PMID:21527772 | nicotine | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Nicotine results in increased expression of KRT80 mRNA | CTD | PMID:23825647 | ozone | decreases expression | ISO | Krt80 (Mus musculus) | 6480464 | Ozone results in decreased expression of KRT80 mRNA | CTD | PMID:33026818 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of KRT80 mRNA | CTD | PMID:33387578 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of KRT80 mRNA | CTD | PMID:32680482 | pentanal | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | pentanal results in increased expression of KRT80 mRNA | CTD | PMID:26079696 | perfluorooctane-1-sulfonic acid | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in increased expression of KRT80 mRNA | CTD | PMID:27153767 | propanal | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of KRT80 mRNA | CTD | PMID:26079696 | rac-lactic acid | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KRT80 mRNA | CTD | PMID:30851411 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of KRT80 mRNA | CTD | PMID:35811015 | S-(1,2-dichlorovinyl)-L-cysteine | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of KRT80 mRNA | CTD | PMID:35811015 | silicon dioxide | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of KRT80 mRNA | CTD | PMID:25895662 | sodium arsenate | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of KRT80 mRNA | CTD | PMID:32525701 | sodium dodecyl sulfate | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in decreased expression of KRT80 mRNA | CTD | PMID:31734321 | sodium fluoride | increases expression | ISO | Krt80 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of KRT80 mRNA | CTD | PMID:27862939 | sulforaphane | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of KRT80 mRNA | CTD | PMID:31838189 | sunitinib | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of KRT80 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of KRT80 mRNA | CTD | PMID:31758290 | testosterone | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Testosterone results in increased expression of KRT80 mRNA | CTD | PMID:21592394 | testosterone | multiple interactions | ISO | KRT80 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of KRT80 mRNA | CTD | PMID:21592394 | titanium dioxide | decreases expression | ISO | Krt80 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of KRT80 mRNA | CTD | PMID:29264374 | trichloroethene | decreases expression | ISO | Krt80 (Mus musculus) | 6480464 | Trichloroethylene results in decreased expression of KRT80 mRNA | CTD | PMID:25549359 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of KRT80 mRNA | CTD | PMID:33387578 | valproic acid | increases expression | ISO | KRT80 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of KRT80 mRNA | CTD | PMID:23179753 | valproic acid | increases methylation | ISO | KRT80 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of KRT80 gene | CTD | PMID:29154799 | zoledronic acid | decreases expression | ISO | KRT80 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of KRT80 mRNA | CTD | PMID:24714768 | |