Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | RGD:1321471 | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of SCRIB mRNA | CTD | PMID:24763279 | 17beta-estradiol | increases phosphorylation | ISO | RGD:1321471 | 6480464 | Estradiol results in increased phosphorylation of SCRIB protein | CTD | PMID:27026707 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | RGD:1321471 | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1321472 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SCRIB mRNA | CTD | PMID:15328365 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SCRIB mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1321472 | 6480464 | Tetrachlorodibenzodioxin affects the expression of SCRIB mRNA | CTD | PMID:21570461 | 2,4,6-tribromophenol | decreases expression | ISO | RGD:1321471 | 6480464 | 2 more ... | CTD | PMID:31675489 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | RGD:1321471 | 6480464 | tetrabromobisphenol A results in decreased expression of SCRIB protein | CTD | PMID:31675489 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1321471 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SCRIB mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SCRIB mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RGD:1321471 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SCRIB mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | affects methylation | ISO | RGD:1321472 | 6480464 | bis(4-hydroxyphenyl)sulfone affects the methylation of SCRIB gene | CTD | PMID:31683443 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SCRIB mRNA | CTD | PMID:36041667 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1321471 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of SCRIB protein | CTD | PMID:31945527 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1321472 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of SCRIB mRNA | CTD | PMID:33297965 | acrolein | multiple interactions | ISO | RGD:1321471 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SCRIB mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SCRIB mRNA | CTD | PMID:32699268 | acrylamide | decreases expression | ISO | RGD:1321471 | 6480464 | Acrylamide results in decreased expression of SCRIB mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | ISO | RGD:1321472 | 6480464 | Aflatoxin B1 results in increased expression of SCRIB mRNA | CTD | PMID:19770486 | alpha-pinene | multiple interactions | ISO | RGD:1321471 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SCRIB mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SCRIB mRNA | CTD | PMID:32699268 | arsane | affects methylation | ISO | RGD:1321471 | 6480464 | Arsenic affects the methylation of SCRIB gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1321471 | 6480464 | Arsenic affects the methylation of SCRIB gene | CTD | PMID:25304211 | arsenite(3-) | multiple interactions | ISO | RGD:1321471 | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to SCRIB mRNA] | CTD | PMID:32406909 | atrazine | decreases expression | ISO | RGD:1321471 | 6480464 | Atrazine results in decreased expression of SCRIB mRNA | CTD | PMID:22378314 | benzo[a]pyrene | multiple interactions | ISO | RGD:1321472 | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to SCRIB promoter] | CTD | PMID:19654925 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SCRIB mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SCRIB mRNA | CTD | PMID:36041667 | bisphenol A | decreases methylation | ISO | RGD:1321471 | 6480464 | bisphenol A results in decreased methylation of SCRIB gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | RGD:1321471 | 6480464 | bisphenol A results in decreased expression of SCRIB protein | CTD | PMID:31675489 | bisphenol F | multiple interactions | ISO | RGD:1321471 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SCRIB mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SCRIB mRNA | CTD | PMID:36041667 | cadmium atom | decreases expression | ISO | RGD:1321472 | 6480464 | Cadmium results in decreased expression of SCRIB mRNA | CTD | PMID:24067728 | caffeine | affects phosphorylation | ISO | RGD:1321471 | 6480464 | Caffeine affects the phosphorylation of SCRIB protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | RGD:1321471 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SCRIB gene] | CTD | PMID:28238834 | cobalt dichloride | decreases expression | ISO | RGD:1321471 | 6480464 | cobaltous chloride results in decreased expression of SCRIB mRNA | CTD | PMID:19320972 | coumarin | affects phosphorylation | ISO | RGD:1321471 | 6480464 | coumarin affects the phosphorylation of SCRIB protein | CTD | PMID:35688186 | decabromodiphenyl ether | decreases expression | ISO | RGD:1321471 | 6480464 | decabromobiphenyl ether results in decreased expression of SCRIB protein | CTD | PMID:31675489 | dexamethasone | multiple interactions | ISO | RGD:1321471 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SCRIB mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SCRIB mRNA | CTD | PMID:28628672 | dicrotophos | increases expression | ISO | RGD:1321471 | 6480464 | dicrotophos results in increased expression of SCRIB mRNA | CTD | PMID:28302478 | dioxygen | increases expression | ISO | RGD:1321472 | 6480464 | Oxygen deficiency results in increased expression of SCRIB mRNA | CTD | PMID:24205000 | disodium selenite | increases expression | ISO | RGD:1321471 | 6480464 | Sodium Selenite results in increased expression of SCRIB mRNA | CTD | PMID:18175754 | enzyme inhibitor | multiple interactions | ISO | RGD:1321471 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SCRIB protein | CTD | PMID:23301498 | epoxiconazole | increases expression | ISO | RGD:1321472 | 6480464 | epoxiconazole results in increased expression of SCRIB mRNA | CTD | PMID:35436446 | ethanol | decreases expression | ISO | RGD:1321471 | 6480464 | Ethanol results in decreased expression of SCRIB protein | CTD | PMID:20621659 | ethanol | increases expression | ISO | RGD:1321472 | 6480464 | Ethanol results in increased expression of SCRIB mRNA | CTD | PMID:30319688 | ethanol | affects splicing | ISO | RGD:1321472 | 6480464 | Ethanol affects the splicing of SCRIB mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | RGD:1321471 | 6480464 | Ethyl Methanesulfonate results in increased expression of SCRIB mRNA | CTD | PMID:23649840 | formaldehyde | increases expression | ISO | RGD:1321471 | 6480464 | Formaldehyde results in increased expression of SCRIB mRNA | CTD | PMID:23649840 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SCRIB mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | RGD:1321471 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SCRIB mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SCRIB mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | RGD:1321471 | 6480464 | Ivermectin results in decreased expression of SCRIB protein | CTD | PMID:32959892 | methyl methanesulfonate | increases expression | ISO | RGD:1321471 | 6480464 | Methyl Methanesulfonate results in increased expression of SCRIB mRNA | CTD | PMID:23649840 | ozone | multiple interactions | ISO | RGD:1321471 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SCRIB mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | ISO | RGD:1321472 | 6480464 | Acetaminophen affects the expression of SCRIB mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SCRIB mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | RGD:1321471 | 6480464 | Acetaminophen results in increased expression of SCRIB mRNA | CTD | PMID:22230336 | quercetin | decreases phosphorylation | ISO | RGD:1321471 | 6480464 | Quercetin results in decreased phosphorylation of SCRIB protein | CTD | PMID:35688186 | resveratrol | multiple interactions | ISO | RGD:1321471 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SCRIB mRNA | CTD | PMID:23557933 | sodium arsenite | decreases expression | ISO | RGD:1321471 | 6480464 | sodium arsenite results in decreased expression of SCRIB mRNA | CTD | PMID:34032870 | sunitinib | increases expression | ISO | RGD:1321471 | 6480464 | Sunitinib results in increased expression of SCRIB mRNA | CTD | PMID:31533062 | tetrachloromethane | increases expression | ISO | RGD:1321472 | 6480464 | Carbon Tetrachloride results in increased expression of SCRIB mRNA | CTD | PMID:31919559 | tungsten | decreases expression | ISO | RGD:1321472 | 6480464 | Tungsten results in decreased expression of SCRIB mRNA | CTD | PMID:30912803 | valproic acid | increases methylation | ISO | RGD:1321471 | 6480464 | Valproic Acid results in increased methylation of SCRIB gene | CTD | PMID:29154799 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of SCRIB mRNA | CTD | PMID:23034163 | | 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