Ccn4 (cellular communication network factor 4)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer VCMap Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Ccn4 (cellular communication network factor 4) Rattus norvegicus

Analyze

Symbol:

Ccn4

Name:

cellular communication network factor 4

RGD ID:

69431

Description:

Predicted to enable heparin binding activity and integrin binding activity. Involved in positive regulation of cell growth involved in cardiac muscle cell development; positive regulation of smooth muscle cell migration; and positive regulation of smooth muscle cell proliferation. Predicted to be located in cytosol and extracellular space. Predicted to be active in extracellular matrix. Orthologous to human CCN4 (cellular communication network factor 4); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CCN family member 4; ELM-1; MGC93340; WISP-1; Wisp1; WNT1 inducible signaling pathway protein 1; WNT1-inducible-signaling pathway protein 1

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	98,645,238 - 98,677,253 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	7	98,645,182 - 98,677,248 (+)	Ensembl
Rnor_6.0	7	107,695,227 - 107,723,759 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	107,695,215 - 107,723,772 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	107,644,976 - 107,673,508 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	104,263,089 - 104,291,621 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	104,297,318 - 104,325,846 (+)	NCBI
Celera	7	95,196,524 - 95,225,037 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Airway Remodeling (IMP)

benign neonatal seizures (ISO)

Charcot-Marie-Tooth disease type 4 (ISO)

Experimental Liver Cirrhosis (IEP)

Hyperoxia (IEP)

Neoplasm Metastasis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-trinitrobenzenesulfonic acid (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-methylcholanthrene (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

actinomycin D (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

carmustine (ISO)

chloroprene (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

Cuprizon (EXP)

cycloheximide (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

doxorubicin (ISO)

fenvalerate (EXP)

folic acid (ISO)

gentamycin (EXP)

graphite (EXP)

homocysteine (ISO)

indometacin (ISO)

methotrexate (ISO)

methylmercury chloride (ISO)

N-nitrosodiethylamine (ISO)

nitrofen (EXP)

nitroprusside (ISO)

ochratoxin A (ISO)

oxaliplatin (EXP)

paracetamol (EXP)

pentane-2,3-dione (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

propiconazole (ISO)

silver atom (ISO)

silver(0) (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

trimellitic anhydride (ISO)

troglitazone (ISO)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bone development (IEA,ISO)

cell adhesion (IBA)

glucose homeostasis (IEA,ISO)

negative regulation of cell death (IBA)

negative regulation of chondrocyte differentiation (IEA,ISO)

negative regulation of fat cell differentiation (IEA,ISO)

osteoblast differentiation (IEA,ISO)

osteoclast differentiation (IEA,ISO)

positive regulation of cell growth involved in cardiac muscle cell development (IMP)

positive regulation of inflammatory response (IEA,ISO)

positive regulation of osteoblast differentiation (IEA,ISO)

positive regulation of smooth muscle cell migration (IMP)

positive regulation of smooth muscle cell proliferation (IMP)

positive regulation of Wnt signaling pathway (IEA,ISO)

positive regulation of wound healing (IEA,ISO)

regulation of cytokine production (IEA,ISO)

signal transduction (IBA,IEA)

Wnt signaling pathway (IEA)

Cellular Component

cellular_component (ND)

cytoplasm (ISO,ISS)

cytosol (IEA,ISO)

extracellular matrix (IBA)

extracellular space (IEA,ISO,ISS)

Molecular Function

heparin binding (IBA)

integrin binding (IBA)

molecular_function (ND)

protein binding (ISO)

References

References - curated


1.	Alapati D, etal., Pediatr Res. 2013 Jun;73(6):719-25. doi: 10.1038/pr.2013.42. Epub 2013 Mar 12.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA data from the GO Consortium
4.	Jian YC, etal., Clin Lab. 2014;60(1):29-35.
5.	Liu H, etal., Mol Cells. 2013 Aug;36(2):112-8. doi: 10.1007/s10059-013-0012-2. Epub 2013 Jun 25.
6.	MGD data from the GO Consortium
7.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	RGD automated data pipeline
9.	RGD automated import pipeline for gene-chemical interactions
10.	RGD comprehensive gene curation
11.	Shanmugam P, etal., J Mol Cell Cardiol. 2011 Mar 2.
12.	Sleeman MA, etal., Genomics 2000 Oct 15;69(2):214-24.
13.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14.	Tanaka S, etal., Oncogene 2001 Sep 6;20(39):5525-32.
15.	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
16.	Yang M, etal., Int Immunopharmacol. 2013 Oct;17(2):350-7. doi: 10.1016/j.intimp.2013.06.011. Epub 2013 Jul 8.

Additional References at PubMed

PMID:15331410	PMID:17616748	PMID:20684029	PMID:22272766	PMID:22475393	PMID:24006456	PMID:25281430	PMID:25864198	PMID:26242865	PMID:26627308	PMID:28496206	PMID:29319180
PMID:29330021	PMID:30556898

Genomics

Comparative Map Data

Ccn4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	98,645,238 - 98,677,253 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	7	98,645,182 - 98,677,248 (+)	Ensembl
Rnor_6.0	7	107,695,227 - 107,723,759 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	107,695,215 - 107,723,772 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	107,644,976 - 107,673,508 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	104,263,089 - 104,291,621 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	104,297,318 - 104,325,846 (+)	NCBI
Celera	7	95,196,524 - 95,225,037 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

CCN4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	133,191,039 - 133,231,690 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	8	133,191,039 - 133,231,690 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	134,203,282 - 134,243,933 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	134,272,494 - 134,310,753 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	8	134,272,493 - 134,309,234	NCBI
Celera	8	130,380,567 - 130,419,496 (+)	NCBI
Cytogenetic Map	8	q24.22	NCBI
HuRef	8	129,522,987 - 129,563,677 (+)	NCBI		HuRef
CHM1_1	8	134,244,050 - 134,284,955 (+)	NCBI		CHM1_1

Ccn4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	66,763,218 - 66,795,054 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	15	66,763,169 - 66,795,050 (+)	Ensembl
GRCm38	15	66,891,369 - 66,923,201 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	66,891,320 - 66,923,201 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	66,722,955 - 66,754,761 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	15	66,721,062 - 66,752,868 (+)	NCBI			mm8
Celera	15	68,424,047 - 68,455,874 (+)	NCBI		Celera
Cytogenetic Map	15	D2	NCBI
cM Map	15	29.3	NCBI

Ccn4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955461	7,748,005 - 7,780,427 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955461	7,748,399 - 7,780,359 (+)	NCBI	ChiLan1.0	ChiLan1.0

CCN4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	8	132,818,397 - 132,858,861 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	132,818,397 - 132,858,861 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	8	129,842,580 - 129,884,528 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

CCN4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	29,648,720 - 29,683,822 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	29,648,639 - 29,679,732 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	29,622,701 - 29,661,265 (+)	NCBI
ROS_Cfam_1.0	13	30,004,803 - 30,043,373 (+)	NCBI
ROS_Cfam_1.0 Ensembl	13	30,004,755 - 30,039,284 (+)	Ensembl
UMICH_Zoey_3.1	13	29,731,434 - 29,769,975 (+)	NCBI
UNSW_CanFamBas_1.0	13	29,830,792 - 29,869,352 (+)	NCBI
UU_Cfam_GSD_1.0	13	30,180,453 - 30,219,020 (+)	NCBI

Ccn4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	8,682,581 - 8,708,143 (-)	NCBI
SpeTri2.0	NW_004936470	16,110,492 - 16,134,065 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCN4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	8,078,156 - 8,110,829 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	8,078,163 - 8,110,906 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	8,188,614 - 8,216,061 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCN4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	127,620,635 - 127,658,132 (+)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	8	127,642,598 - 127,661,462 (+)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666039	12,440,154 - 12,481,049 (-)	NCBI	Vero_WHO_p1.0

Ccn4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624735	22,789,784 - 22,819,527 (-)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

BE117857

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	98,673,862 - 98,674,012 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	107,723,549 - 107,723,698	NCBI	Rnor6.0
Rnor_5.0	7	107,673,298 - 107,673,447	UniSTS	Rnor5.0
RGSC_v3.4	7	104,291,411 - 104,291,560	UniSTS	RGSC3.4
Celera	7	95,224,827 - 95,224,976	UniSTS
RH 3.4 Map	7	681.1	UniSTS
Cytogenetic Map	7	q33	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
71114	Niddm14	Non-insulin dependent diabetes mellitus QTL 14	4.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	84257275	129257275	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	62004452	101773158	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	80221299	124373579	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	80221299	112308525	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	80221299	125221299	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	62004452	101773158	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	91412594	129807172	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	61074194	106074194	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	96670164	135012528	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	80221299	109401111	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	69736226	117455174	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	53612714	103945643	Rat
2298475	Eau6	Experimental allergic uveoretinitis QTL 6		0.0029	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	7	84257275	129257275	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	83153392	128153392	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	73829340	130221005	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
1357336	Gluco6	Glucose level QTL 6	3.4		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	7	94811326	116294265	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	69736356	112729554	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	43747099	102228765	Rat
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	91281130	135012528	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	90482196	135012528	Rat
1558655	Swd4	Spike wave discharge measurement QTL 4	3.68	0.0002	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge severity grade (CMO:0001988)	7	86983365	131983365	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	68938720	113886318	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	68938720	113886318	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	68938720	113886318	Rat
2317035	Aia16	Adjuvant induced arthritis QTL 16	2.71		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	59238038	104238038	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	81737938	126737938	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	43747012	108555253	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	94811085	116738842	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	93595647	106839474	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
10450828	Scl79	Serum cholesterol level QTL 79	3.5	0.001	blood HDL cholesterol amount (VT:0000184)	blood low density lipoprotein cholesterol level (CMO:0000053)	7	89867376	101773158	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	71
Count of miRNA genes:	55
Interacting mature miRNAs:	67
Transcripts:	ENSRNOT00000009673
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		4								10	9
Low	3	23	13	10	2	10	6	9	50	25	24	9	6
Below cutoff		15	31	18	17	18	2	2	20		5	2	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC091481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF228049	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ236871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000009673 ⟹ ENSRNOP00000009673

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	98,645,610 - 98,677,248 (+)	Ensembl
Rnor_6.0 Ensembl	7	107,695,227 - 107,723,764 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093628 ⟹ ENSRNOP00000076326

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	98,645,623 - 98,674,090 (+)	Ensembl
Rnor_6.0 Ensembl	7	107,695,215 - 107,723,772 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104468 ⟹ ENSRNOP00000084936

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	98,645,615 - 98,676,229 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000108383 ⟹ ENSRNOP00000085026

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	98,645,182 - 98,673,272 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000110857 ⟹ ENSRNOP00000090079

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	98,645,617 - 98,661,880 (+)	Ensembl

RefSeq Acc Id:

NM_031716 ⟹ NP_113904

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	98,645,542 - 98,674,073 (+)	NCBI
Rnor_6.0	7	107,695,227 - 107,723,759 (+)	NCBI
Rnor_5.0	7	107,644,976 - 107,673,508 (+)	NCBI
RGSC_v3.4	7	104,263,089 - 104,291,621 (+)	RGD
Celera	7	95,196,524 - 95,225,037 (+)	RGD

Sequence:

show sequence

GGCACGAGGCCTGACGTCAGATGTCGCTTTGACAAACGCCCCCGGGGGCTGAGGAAGGCTCTCC
GCTGCTCTGATGGGCCAGCCCAGTCGTGGCCCAGCTCCCTGGAGAGGCACCGGCATCCTCTGGG
CTGAGCTGTAGCTCCTGTGACGCTGACTTCCAGGCATGAGGTGGCTCCTGCCCTGGACGCTGGC
AGCCGTGGCAGTCCTGATGGTGGGCAACATCCTGGCCACGGCCCTCTCTCCAACCCCCACAACC
ATGACCTTCACCCCAGCACCACTGGAGGAAACGATTACACGGCCGGAATTCTGCAAGTGGCCGT
GTGAGTGCCCACAAGCCCCACCTCGCTGCCCACTGGGTGTCAGCCTAATCACAGATGGCTGTGA
ATGCTGTAAGATATGTGCCCAGCAGCTTGGGGACAACTGCACAGAGGCTGCCGTCTGTGACCCA
CACCGGGGCCTCTACTGCGATTACAGTGGGGACCGCCCGAGGTACGCAATAGGAGTGTGTGCAC
AGGTGGTCGGTGTGGGCTGTGTCCTGGATGGCGTGCGCTACACCAATGGAGAGTCCTTCCAACC
CAACTGCAGGTACAACTGCACCTGTATTGATGGCACCGTGGGCTGCACACCACTGTGCCTGAGC
CCCAGGCCCCCACGCCTCTGGTGCCGCCAGCCCCGTCACGTGAGAGTCCCTGGCCAGTGCTGTG
AACAATGGGTATGTGATGATGATGCCAGGAGGCCACGCCAGACTGCACTGCTGGACACCAGAGC
CTTTGCAGCTTCGGGTGCAGTGGAGCAACGGTATGAGAACTGCATAGCCTACACTAGCCCCTGG
AGTCCCTGCTCAACAACCTGTGGCCTAGGTATCTCGACTCGCATCTCTAATGTCAATGCGCGGT
GCTGGCCAGAGCAGGAAAGTCGCCTCTGCAACCTGCGGCCATGTGATGTGGACATCCGACCACA
CATCAAGGCAGGGAAGAAATGCCTGGCTGTGTACCAGCCAGAGGAGGCCACGAACTTCACTCTC
GCAGGCTGTGTCAGCACACGCACCTACCGACCCAAGTACTGTGGAGTCTGTACTGACAATAGGT
GTTGCATCCCCTACAAGTCTAAGACCATCAGTGTTGATTTCCAGTGTCCAGAGGGGCCGGGTTT
CTCTCGGCAGGTCCTATGGATTAATGCTTGCTTCTGCAACCTGAGCTGCAGGAATCCTAATGAT
ATCTTTGCTGACTTGGAATCTTACCCTGACTTTGCAGAGATTGCCAACTAGGTAGGTGTGTGGC
TTGGAGAACAGCTCCATGTTGCAAAGCAGTCAGCCCTCTGTGGCCCAGGACTTCACAATTGAGC
CTTATTTCATCTACTTCCTCCTCAATTCTGCATTCCCTGACCCTGACCCTCAGTTTCTGTTCCT
ATTTTGACCGTTCCAATGGCCCAGGAAAGTGCTGCTCAGGCTCAGACAATGGGTCCCTCCTTTG
GGACATTCTATATCACTCCAAGGAAAACACCTCTCTGAACTGTTCACAATGAAAGCCAAGCCTG
ACCCCAGCCAGTCTGGCTCCAACCTGTGCAAGTTGTCAGAAATCCTAATGGGACAGTCCAAGGA
AAAAACAGCAACTGAAGAACCAGAATCACAGACTCCCTCTTCAGATGCCCAGCCTGAGGATGTT
GAGATCCTTTCAGACACATGGATGGGATTGGGGGAACGGGAATAAGCTATCATCCCTTACCAAA
TGATACTATCCTGGGAATTTCTGCCCACAACATACCAAAAGTGCTCTTATTCCAAAGATCTATG
TATCACAAGTCACCAAACATGTTCTAGGTGAGGAAAATACTTGCACCATTTTGATTTGAAATTG
AAAATCATATTTAAAAGAAGAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039079864 ⟹ XP_038935792

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	98,645,238 - 98,677,253 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_113904	(Get FASTA)	NCBI Sequence Viewer
	XP_038935792	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78787	(Get FASTA)	NCBI Sequence Viewer
	AAK00729	(Get FASTA)	NCBI Sequence Viewer
	CAB41995	(Get FASTA)	NCBI Sequence Viewer
	EDM16148	(Get FASTA)	NCBI Sequence Viewer
	EDM16149	(Get FASTA)	NCBI Sequence Viewer
	EDM16150	(Get FASTA)	NCBI Sequence Viewer
	EDM16151	(Get FASTA)	NCBI Sequence Viewer
	Q99PP0	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_113904 ⟸ NM_031716

- Peptide Label:

precursor

- Sequence:

show sequence

MRWLLPWTLAAVAVLMVGNILATALSPTPTTMTFTPAPLEETITRPEFCKWPCECPQAPPRCPL
GVSLITDGCECCKICAQQLGDNCTEAAVCDPHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGV
RYTNGESFQPNCRYNCTCIDGTVGCTPLCLSPRPPRLWCRQPRHVRVPGQCCEQWVCDDDARRP
RQTALLDTRAFAASGAVEQRYENCIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESRLCNL
RPCDVDIRPHIKAGKKCLAVYQPEEATNFTLAGCVSTRTYRPKYCGVCTDNRCCIPYKSKTISV
DFQCPEGPGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFAEIAN

hide sequence

RefSeq Acc Id:

ENSRNOP00000076326 ⟸ ENSRNOT00000093628

RefSeq Acc Id:

ENSRNOP00000009673 ⟸ ENSRNOT00000009673

RefSeq Acc Id:	XP_038935792 ⟸ XM_039079864
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000090079 ⟸ ENSRNOT00000110857

RefSeq Acc Id:

ENSRNOP00000085026 ⟸ ENSRNOT00000108383

RefSeq Acc Id:

ENSRNOP00000084936 ⟸ ENSRNOT00000104468

Protein Domains

CTCK IGFBP N-terminal TSP type-1 VWFC

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q99PP0-F1-model_v2	AlphaFold	Q99PP0	1-367	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695365

Promoter ID:

EPDNEW_R5890

Type:

initiation region

Name:

Wisp1_1

Description:

WNT1 inducible signaling pathway protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	107,695,305 - 107,695,365	EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)

ACI/EurMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69431	AgrOrtholog
BioCyc Gene	G2FUF-33119	BioCyc
Ensembl Genes	ENSRNOG00000007078	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000009673	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000076326	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000009673	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000093628	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	2.20.100.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7131232	IMAGE-MGC_LOAD
InterPro	Cys_knot_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hormone_CN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Growth_fac_rcpt_cys_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IGFBP-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IGFBP_CNN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Insulin_GF-bd_Cys-rich_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1_CCN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1_rpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1_rpt_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	VWF_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:65154	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93340	IMAGE-MGC_LOAD
NCBI Gene	65154	ENTREZGENE
Pfam	Cys_knot	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IGFBP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1_CCN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	VWC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ccn4	PhenoGen
PIRSF	IGFBP_rP_CNN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	CTCK_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CTCK_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IGFBP_N_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IGFBP_N_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	VWFC_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	VWFC_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	SM00041	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00121	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	VWC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF57184	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF82895	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC206062
UniProt	A0A1W2Q6N9_RAT	UniProtKB/TrEMBL
	G3V6X0_RAT	UniProtKB/TrEMBL
	Q99PP0	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q9WUW4	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-10-23	Ccn4	cellular communication network factor 4	Wisp1	WNT1 inducible signaling pathway protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Wisp1	WNT1 inducible signaling pathway protein 1			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD