Gene: Irak4 (interleukin-1 receptor-associated kinase 4) Rattus norvegicus
Symbol: Irak4
Name: interleukin-1 receptor-associated kinase 4
Description: ENCODES a protein that exhibits interleukin-1 receptor binding (ortholog); protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway; JNK cascade; positive regulation of smooth muscle cell proliferation; PARTICIPATES IN interleukin-1 signaling pathway; Toll-like receptor signaling pathway; apoptotic cell death pathway; ASSOCIATED WITH Brain Ischemia; Sepsis; Bacterial Infections and Mycoses (ortholog); FOUND IN extracellular space; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC300177
Homo sapiens (human) : IRAK4 (interleukin 1 receptor associated kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Irak4 (interleukin-1 receptor-associated kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irak4 (interleukin 1 receptor associated kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : IRAK4 (interleukin 1 receptor associated kinase 4)
Canis lupus familiaris (dog) : IRAK4 (interleukin 1 receptor associated kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irak4 (interleukin 1 receptor associated kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07135,803,723 - 135,831,006 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07135,461,296 - 135,487,468 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47133,055,185 - 133,081,614 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17133,131,009 - 133,157,870 (+)NCBI
Celera7122,072,276 - 122,098,055 (+)NCBICelera
Cytogenetic Map7q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Irak4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305303
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-04-10
Status: ACTIVE