 Gene Ontology Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Function
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
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 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
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Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
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Gene Annotator (Annotation Comparison) |
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Molecular Function
Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Molecular Function
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References - curated| 1. | RGD automated data pipeline |
| 2. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 3. | RGD automated import pipeline for gene-chemical interactions |
| 4. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
| 5. | Wang L, etal., Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1248-53. Epub 2007 Jan 16. |
References - uncuratedGenomics
Comparative Map Data| Arhgap8 (Rattus norvegicus - Norway rat) |
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| ARHGAP8 (Homo sapiens - human) |
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| Arhgap8 (Mus musculus - house mouse) |
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| Arhgap8 (Chinchilla lanigera - long-tailed chinchilla) |
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| ARHGAP8 (Canis lupus familiaris - dog) |
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| ARHGAP8 (Sus scrofa - pig) |
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Position Markers| RH131694 |
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| AU048942 |
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| ha2170 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 4 | 11 | 5 | 10 | ||||||||||||
| Low | 22 | 39 | 12 | 11 | 4 | 3 | 22 | 21 | 11 | 32 | 25 | 8 | 8 | |||
| Below cutoff | 4 | 11 | 1 | 7 | 4 | 4 | 4 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001004242 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_017594772 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594773 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07058581 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07058582 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07058583 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07058584 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051970 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051971 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051972 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051973 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051974 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051975 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051976 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01051977 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC079089 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | NM_001004242 ⟹ NP_001004242 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
GCCAGGTGTGCGGCTAGAGTAGCTGAGATCAGGAGAGGTGCTCGGTGGTCCGAGCTGCAGAGAChide sequence |
| RefSeq Acc Id: | XM_017594772 ⟹ XP_017450261 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
TACTTCGGGAAGCTGGAGGTGGTGGCTTATATTGATCGTCCCCTGAAGTCACAACACCCTCTAGhide sequence |
| RefSeq Acc Id: | XM_017594773 ⟹ XP_017450262 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CAGGACCATGTTCACTTCGTGCAGGGCTGCCGGGCGGTAGAGCTGACTCATCTACTGAGGAAAChide sequence |
Protein Sequences| Protein RefSeqs | NP_001004242 | (Get FASTA) | NCBI Sequence Viewer |
| XP_017450261 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017450262 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAH79089 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001004242 ⟸ NM_001004242 |
| - UniProtKB: | Q6AYD8 (UniProtKB/TrEMBL) |
| - Sequence: |
MAGLDPTLSTSHPFYDVARHGILQVAGDDRQGRRIFTFSCCRLPPLHQLNHQRLLEYLKYTLDQhide sequence |
| RefSeq Acc Id: | XP_017450261 ⟸ XM_017594772 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q6AYD8 (UniProtKB/TrEMBL) |
| - Sequence: |
MAGLDPTLSTSHPFYDVARHGILQVAGDDRQGRRIFTFSCCRLPPLHQLNHQRLLEYLKYTLDQhide sequence |
| RefSeq Acc Id: | XP_017450262 ⟸ XM_017594773 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q6AYD8 (UniProtKB/TrEMBL) |
| - Sequence: |
MAGLDPTLSTSHPFYDVARHGILQVAGDDRQGRRIFTFSCCRLPPLHQLNHQRLLEYLKYTLDQhide sequence |
TranscriptomePromoters| RGD ID: | 13695559 | |||||||||
| Promoter ID: | EPDNEW_R6084 | |||||||||
| Type: | initiation region | |||||||||
| Name: | Arhgap8_1 | |||||||||
| Description: | Rho GTPase activating protein 8 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1303143 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000033570 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000017420 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000017420 | ENTREZGENE, UniProtKB/TrEMBL |
| Gene3D-CATH | 1.10.555.10 | UniProtKB/TrEMBL |
| 3.40.525.10 | UniProtKB/TrEMBL | |
| IMAGE_CLONE | IMAGE:7123477 | IMAGE-MGC_LOAD |
| InterPro | CRAL-TRIO_dom_sf | UniProtKB/TrEMBL |
| CRAL_bd_TRIO_C | UniProtKB/TrEMBL | |
| Rho_GTPase_activation_prot | UniProtKB/TrEMBL | |
| RhoGAP | UniProtKB/TrEMBL | |
| KEGG Report | rno:300115 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:94058 | IMAGE-MGC_LOAD |
| NCBI Gene | 300115 | ENTREZGENE |
| Pfam | CRAL_TRIO_2 | UniProtKB/TrEMBL |
| RhoGAP | UniProtKB/TrEMBL | |
| PhenoGen | Arhgap8 | PhenoGen |
| PROSITE | CRAL_TRIO | UniProtKB/TrEMBL |
| RHOGAP | UniProtKB/TrEMBL | |
| SMART | RhoGAP | UniProtKB/TrEMBL |
| SEC14 | UniProtKB/TrEMBL | |
| Superfamily-SCOP | CRAL_TRIO_C | UniProtKB/TrEMBL |
| Rho_GAP | UniProtKB/TrEMBL | |
| UniGene | Rn.7830 | ENTREZGENE |
| UniProt | Q6AYD8 | ENTREZGENE, UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2005-09-30 | Arhgap8 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
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| More on Arhgap8 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1303143 |
| Created: | 2004-12-03 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-11-27 |
| Status: | ACTIVE |
