Eif3l (eukaryotic translation initiation factor 3, subunit L) - Rat Genome Database

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Gene: Eif3l (eukaryotic translation initiation factor 3, subunit L) Rattus norvegicus
Analyze
Symbol: Eif3l
Name: eukaryotic translation initiation factor 3, subunit L
RGD ID: 1308230
Description: Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation and viral translational termination-reinitiation. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Predicted to be active in synapse. Orthologous to human EIF3L (eukaryotic translation initiation factor 3 subunit L); PARTICIPATES IN translation initiation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Eif3s6ip; eukaryotic translation initiation factor 3 subunit L; eukaryotic translation initiation factor 3, subunit 6 interacting protein; LOC300069; MGC116337
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,522,222 - 112,544,063 (+)NCBIGRCr8
mRatBN7.27110,652,565 - 110,663,614 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,627,107 - 110,663,614 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,401,442 - 112,412,486 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,624,973 - 114,636,017 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,594,116 - 114,605,149 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,320,547 - 120,331,596 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,320,547 - 120,331,595 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,314,626 - 120,325,675 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,062,697 - 117,073,746 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,087,197 - 117,107,975 (+)NCBI
Celera7106,986,607 - 106,997,655 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lRatadenylosuccinase lyase deficiency  ISOEIF3L (Homo sapiens)8554872ClinVar Annotator: match by term: Adenylosuccinate lyase deficiencyClinVarPMID:28492532
Eif3lRatEmery-Dreifuss muscular dystrophy  ISOEIF3L (Homo sapiens)8554872ClinVar Annotator: match by term: Emery-Dreifuss muscular dystrophyClinVarPMID:16783378 more ...
Eif3lRatmyoclonic dystonia 26  ISOEIF3L (Homo sapiens)8554872ClinVar Annotator: match by term: Myoclonic dystonia 26ClinVarPMID:16783378 more ...
Eif3lRatneurodegeneration with brain iron accumulation 2A  ISOEIF3L (Homo sapiens)8554872ClinVar Annotator: match by term: Infantile neuroaxonal dystrophyClinVarPMID:16783378 more ...

1 to 20 of 78 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lRat1,2-dimethylhydrazine decreases expressionISOEif3l (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of EIF3L mRNACTDPMID:22206623
Eif3lRat1,2-dimethylhydrazine multiple interactionsISOEif3l (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3L mRNACTDPMID:22206623
Eif3lRat17alpha-ethynylestradiol multiple interactionsISOEif3l (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EIF3L mRNACTDPMID:17942748
Eif3lRat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in decreased expression of EIF3L mRNACTDPMID:26496021
Eif3lRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOEif3l (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of EIF3L mRNACTDPMID:21570461
Eif3lRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of EIF3L mRNACTDPMID:33387578
Eif3lRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOEif3l (Mus musculus)6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of EIF3L mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EIF3L mRNACTDPMID:16214954 and PMID:17942748
Eif3lRat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of EIF3L mRNACTDPMID:21346803
Eif3lRat2,6-dimethoxyphenol multiple interactionsISOEIF3L (Homo sapiens)6480464[Furaldehyde co-treated with pyrogallol 1 more ...CTDPMID:38598786
Eif3lRat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of EIF3L mRNACTDPMID:21346803
Eif3lRat2-bromohexadecanoic acid multiple interactionsISOEIF3L (Homo sapiens)64804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of EIF3L protein]CTDPMID:38195004
Eif3lRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOEIF3L (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of EIF3L mRNACTDPMID:28628672
Eif3lRat4,4'-sulfonyldiphenol increases expressionISOEif3l (Mus musculus)6480464bisphenol S results in increased expression of EIF3L mRNACTDPMID:39298647
Eif3lRatall-trans-retinoic acid decreases expressionISOEIF3L (Homo sapiens)6480464Tretinoin results in decreased expression of EIF3L mRNACTDPMID:33167477
Eif3lRatantirheumatic drug increases expressionISOEIF3L (Homo sapiens)6480464Antirheumatic Agents results in increased expression of EIF3L mRNACTDPMID:24449571
Eif3lRatarsane multiple interactionsISOEIF3L (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of EIF3L mRNACTDPMID:39836092
Eif3lRatarsenic atom multiple interactionsISOEIF3L (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of EIF3L mRNACTDPMID:39836092
Eif3lRatarsenite(3-) multiple interactionsISOEIF3L (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to EIF3L mRNA]CTDPMID:32406909
Eif3lRatbenzatropine increases expressionISOEIF3L (Homo sapiens)6480464Benztropine results in increased expression of EIF3L proteinCTDPMID:34122009
Eif3lRatbenzatropine multiple interactionsISOEIF3L (Homo sapiens)6480464[Cuprizone co-treated with Benztropine] results in decreased expression of EIF3L proteinCTDPMID:34122009

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Biological Process
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lRatbiological_process  ND 159840701/2016: no relevant rat dataRGD 
Eif3lRatcytoplasmic translational initiation involved_inIEAUniRule:UR0001071161600115GO_REF:0000104UniProtGO_REF:0000104
Eif3lRatformation of cytoplasmic translation initiation complex involved_inIEAUniRule:UR0001071161600115GO_REF:0000104UniProtGO_REF:0000104
Eif3lRattranslation involved_inIEAUniProtKB-KW:KW-06481600115GO_REF:0000043UniProtGO_REF:0000043
Eif3lRattranslational initiation involved_inISOEIF3L (Homo sapiens)1624291 PMID:17581632RGDPMID:17581632
Eif3lRattranslational initiation involved_inIEAUniProtKB-KW:KW-03961600115GO_REF:0000043UniProtGO_REF:0000043
Eif3lRattranslational initiation involved_inIEAUniProtKB:Q8QZY1 and ensembl:ENSMUSP000000388391600115GO_REF:0000107EnsemblGO_REF:0000107
Eif3lRattranslational initiation involved_inIEAUniProtKB:Q9Y262 and ensembl:ENSP000004990671600115GO_REF:0000107EnsemblGO_REF:0000107
Eif3lRattranslational initiation involved_inIBAMGI:2386251 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Eif3lRattranslational initiation involved_inISOEif3l (Mus musculus)1624291 PMID:17581632RGDPMID:17581632
Eif3lRatviral translational termination-reinitiation involved_inISOEIF3L (Homo sapiens)1624291 PMID:21347434RGDPMID:21347434
Eif3lRatviral translational termination-reinitiation involved_inIEAUniProtKB:Q9Y262 and ensembl:ENSP000004990671600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 12 of 12 rows

Cellular Component
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lRatcytoplasm located_inIEAInterPro:IPR0193821600115GO_REF:0000002InterProGO_REF:0000002
Eif3lRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Eif3lRatcytoplasm located_inIEAUniRule:UR0001071161600115GO_REF:0000104UniProtGO_REF:0000104
Eif3lRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Eif3lRateukaryotic 43S preinitiation complex part_ofIEAUniRule:UR0001071161600115GO_REF:0000104UniProtGO_REF:0000104
Eif3lRateukaryotic 48S preinitiation complex part_ofIEAUniRule:UR0001071161600115GO_REF:0000104UniProtGO_REF:0000104
Eif3lRateukaryotic translation initiation factor 3 complex part_ofISOEIF3L (Homo sapiens)1624291 PMID:17322308 more ...RGDPMID:17322308 more ...
Eif3lRateukaryotic translation initiation factor 3 complex part_ofIEAUniProtKB:Q9Y262 and ensembl:ENSP000004990671600115GO_REF:0000107EnsemblGO_REF:0000107
Eif3lRateukaryotic translation initiation factor 3 complex part_ofIEAUniProtKB:Q8QZY1 and ensembl:ENSMUSP000000388391600115GO_REF:0000107EnsemblGO_REF:0000107
Eif3lRateukaryotic translation initiation factor 3 complex part_ofIEAInterPro:IPR0193821600115GO_REF:0000002InterProGO_REF:0000002
Eif3lRateukaryotic translation initiation factor 3 complex part_ofISOEif3l (Mus musculus)1624291 PMID:17581632RGDPMID:17581632
Eif3lRateukaryotic translation initiation factor 3 complex part_ofIEAUniRule:UR0001071161600115GO_REF:0000104UniProtGO_REF:0000104
Eif3lRateukaryotic translation initiation factor 3 complex part_ofIBAMGI:2386251 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Eif3lRatfibrillar center located_inIEAUniProtKB:Q8QZY1 and ensembl:ENSMUSP000000388391600115GO_REF:0000107EnsemblGO_REF:0000107
Eif3lRatfibrillar center located_inISOEif3l (Mus musculus)1624291 PMID:11592397RGDPMID:11592397
Eif3lRatnucleolus located_inISOEif3l (Mus musculus)1624291 PMID:11592397RGDPMID:11592397
Eif3lRatnucleolus located_inIEAUniProtKB:Q8QZY1 and ensembl:ENSMUSP000000388391600115GO_REF:0000107EnsemblGO_REF:0000107
Eif3lRatnucleoplasm located_inISOEif3l (Mus musculus)1624291 PMID:11592397RGDPMID:11592397
Eif3lRatnucleoplasm located_inIEAUniProtKB:Q8QZY1 and ensembl:ENSMUSP000000388391600115GO_REF:0000107EnsemblGO_REF:0000107
Eif3lRatsynapse is_active_inISOEif3l (Mus musculus)1624291 PMID:25211037RGDPMID:25211037
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Molecular Function
1 to 9 of 9 rows

  
1 to 9 of 9 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lRattranslation initiation pathway  ISOEIF3L (Homo sapiens)10002776 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The scanning mechanism of eukaryotic translation initiation. Hinnebusch AG Annu Rev Biochem. 2014;83:779-812. doi: 10.1146/annurev-biochem-060713-035802. Epub 2014 Jan 29.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:11592397   PMID:17322308   PMID:17581632   PMID:18599441   PMID:19946888   PMID:21347434   PMID:22658674   PMID:22681889   PMID:25849773   PMID:33450132  



Eif3l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,522,222 - 112,544,063 (+)NCBIGRCr8
mRatBN7.27110,652,565 - 110,663,614 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,627,107 - 110,663,614 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,401,442 - 112,412,486 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,624,973 - 114,636,017 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,594,116 - 114,605,149 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,320,547 - 120,331,596 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,320,547 - 120,331,595 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,314,626 - 120,325,675 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,062,697 - 117,073,746 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,087,197 - 117,107,975 (+)NCBI
Celera7106,986,607 - 106,997,655 (+)NCBICelera
Cytogenetic Map7q34NCBI
EIF3L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,849,419 - 37,889,407 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,848,868 - 37,889,407 (+)EnsemblGRCh38hg38GRCh38
GRCh372238,245,426 - 38,285,414 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,575,316 - 36,614,584 (+)NCBINCBI36Build 36hg18NCBI36
Build 342236,569,869 - 36,609,137NCBI
Celera2222,047,135 - 22,086,399 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,211,745 - 21,251,253 (+)NCBIHuRef
CHM1_12238,204,124 - 38,243,546 (+)NCBICHM1_1
T2T-CHM13v2.02238,311,024 - 38,351,034 (+)NCBIT2T-CHM13v2.0
Eif3l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,959,423 - 78,978,600 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,959,379 - 78,978,605 (+)EnsemblGRCm39 Ensembl
GRCm381579,075,223 - 79,094,400 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,075,179 - 79,094,405 (+)EnsemblGRCm38mm10GRCm38
MGSCv371578,905,653 - 78,924,830 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,902,478 - 78,921,655 (+)NCBIMGSCv36mm8
Celera1581,181,022 - 81,207,760 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Eif3l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,220,188 - 24,254,176 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541324,220,188 - 24,250,786 (+)NCBIChiLan1.0ChiLan1.0
EIF3L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,709,371 - 47,747,242 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,397,954 - 50,435,602 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,765,793 - 18,803,910 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,595,956 - 36,632,513 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,595,956 - 36,632,513 (+)Ensemblpanpan1.1panPan2
EIF3L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,757,639 - 26,784,908 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,757,639 - 26,785,008 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,712,671 - 26,739,746 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,549,474 - 27,576,553 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,549,474 - 27,577,389 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,272,520 - 27,299,587 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,580,826 - 27,607,864 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,758,191 - 27,785,460 (-)NCBIUU_Cfam_GSD_1.0
Eif3l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,221,647 - 10,264,959 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364923,244,497 - 3,275,342 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF3L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,968,428 - 10,000,092 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,970,013 - 9,996,086 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,465,989 - 7,492,101 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EIF3L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,555,632 - 20,594,335 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045105,189,979 - 105,231,491 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif3l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,034,518 - 10,067,231 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,034,518 - 10,066,449 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Eif3l
21 total Variants

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:105
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000014817
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat

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alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000014817   ⟹   ENSRNOP00000014817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7110,643,203 - 110,663,614 (+)Ensembl
Rnor_6.0 Ensembl7120,320,547 - 120,331,595 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102081   ⟹   ENSRNOP00000078639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7110,627,107 - 110,663,614 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119926   ⟹   ENSRNOP00000076747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7110,654,044 - 110,663,614 (+)Ensembl
RefSeq Acc Id: NM_001034134   ⟹   NP_001029306
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,533,014 - 112,544,063 (+)NCBI
mRatBN7.27110,652,565 - 110,663,614 (+)NCBI
Rnor_6.07120,320,547 - 120,331,596 (+)NCBI
Rnor_5.07120,314,626 - 120,325,675 (+)NCBI
RGSC_v3.47117,062,697 - 117,073,746 (+)RGD
Celera7106,986,607 - 106,997,655 (+)RGD
Sequence:
RefSeq Acc Id: XM_063263318   ⟹   XP_063119388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,522,222 - 112,544,063 (+)NCBI
RefSeq Acc Id: XM_063263319   ⟹   XP_063119389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,525,444 - 112,544,063 (+)NCBI
1 to 9 of 9 rows
Protein RefSeqs NP_001029306 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119388 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119389 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00265 (Get FASTA)   NCBI Sequence Viewer  
  EDM15826 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014817
  ENSRNOP00000014817.6
  ENSRNOP00000076747.1
  ENSRNOP00000078639.1
1 to 9 of 9 rows
RefSeq Acc Id: NP_001029306   ⟸   NM_001034134
- UniProtKB: A6HSP6 (UniProtKB/TrEMBL),   G3V7G9 (UniProtKB/TrEMBL),   Q498D2 (UniProtKB/TrEMBL),   A0A8I5ZLD0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014817   ⟸   ENSRNOT00000014817
Ensembl Acc Id: ENSRNOP00000078639   ⟸   ENSRNOT00000102081
Ensembl Acc Id: ENSRNOP00000076747   ⟸   ENSRNOT00000119926
RefSeq Acc Id: XP_063119388   ⟸   XM_063263318
- Peptide Label: isoform X1
PCI

Name Modeler Protein Id AA Range Protein Structure
AF-G3V7G9-F1-model_v2 AlphaFold G3V7G9 1-382 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-32782 BioCyc
Ensembl Genes ENSRNOG00000011020 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014817 ENTREZGENE
  ENSRNOT00000014817.7 UniProtKB/TrEMBL
  ENSRNOT00000102081.1 UniProtKB/TrEMBL
  ENSRNOT00000119926.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7382342 IMAGE-MGC_LOAD
InterPro PCI_dom UniProtKB/TrEMBL
  RNA_pol1-assoc_factor_Paf67 UniProtKB/TrEMBL
  TPR-like_helical_dom UniProtKB/TrEMBL
KEGG Report rno:300069 UniProtKB/TrEMBL
MGC_CLONE MGC:116337 IMAGE-MGC_LOAD
NCBI Gene 300069 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L UniProtKB/TrEMBL
  PTHR13242 UniProtKB/TrEMBL
Pfam Paf67 UniProtKB/TrEMBL
PhenoGen Eif3l PhenoGen
PROSITE PCI UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011020 RatGTEx
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A8I5Y0Q4_RAT UniProtKB/TrEMBL
  A0A8I5ZLD0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8YB26 ENTREZGENE, UniProtKB/TrEMBL
  A6HSP6 ENTREZGENE, UniProtKB/TrEMBL
  G3V7G9 ENTREZGENE, UniProtKB/TrEMBL
  Q498D2 ENTREZGENE
UniProt Secondary Q498D2 UniProtKB/TrEMBL
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-01 Eif3l  eukaryotic translation initiation factor 3, subunit L  Eif3s6ip  eukaryotic translation initiation factor 3, subunit 6 interacting protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Eif3s6ip  eukaryotic translation initiation factor 3, subunit 6 interacting protein  Eif3s6ip_predicted  eukaryotic translation initiation factor 3, subunit 6 interacting protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Eif3s6ip_predicted  eukaryotic translation initiation factor 3, subunit 6 interacting protein (predicted)      Symbol and Name status set to approved 70820 APPROVED