Eif3l (eukaryotic translation initiation factor 3 subunit L) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Eif3l (eukaryotic translation initiation factor 3 subunit L) Chinchilla lanigera
Analyze
Symbol: Eif3l
Name: eukaryotic translation initiation factor 3 subunit L
RGD ID: 8735755
Description: ENCODES a protein that exhibits translation initiation factor activity (ortholog); INVOLVED IN translational initiation (ortholog); viral translational termination-reinitiation (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Emery-Dreifuss muscular dystrophy (ortholog); myoclonic dystonia 26 (ortholog); FOUND IN eukaryotic translation initiation factor 3 complex (ortholog); fibrillar center (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: eukaryotic translation initiation factor 3, subunit L
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,220,188 - 24,254,176 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541324,220,188 - 24,250,786 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lChinchillaadenylosuccinase lyase deficiency  ISORGD:13178858554872ClinVar Annotator: match by term: Adenylosuccinate lyase deficiencyClinVarPMID:28492532
Eif3lChinchillaEmery-Dreifuss muscular dystrophy  ISORGD:13178858554872ClinVar Annotator: match by term: Emery-Dreifuss muscular dystrophyClinVarPMID:16783378|PMID:18570303|PMID:18799783|PMID:22213678|PMID:28492532
Eif3lChinchillamyoclonic dystonia 26  ISORGD:13178858554872ClinVar Annotator: match by term: Myoclonic dystonia 26ClinVarPMID:16783378|PMID:18570303|PMID:18799783|PMID:22213678|PMID:28492532
Eif3lChinchillaneurodegeneration with brain iron accumulation 2A  ISORGD:13178858554872ClinVar Annotator: match by term: Infantile neuroaxonal dystrophyClinVarPMID:16783378|PMID:18570303|PMID:18799783|PMID:22213678|PMID:28492532


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lChinchillatranslational initiation involved_inISORGD:13178869068941 PMID:17581632UniProtPMID:17581632
Eif3lChinchillatranslational initiation involved_inISORGD:13178859068941 PMID:17581632UniProtPMID:17581632
Eif3lChinchillaviral translational termination-reinitiation involved_inISORGD:13178859068941 PMID:21347434UniProtPMID:21347434

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lChinchillaeukaryotic translation initiation factor 3 complex part_ofISORGD:13178869068941 PMID:17581632UniProtPMID:17581632
Eif3lChinchillaeukaryotic translation initiation factor 3 complex part_ofISORGD:13178859068941 PMID:17322308, PMID:17581632, PMID:18599441, PMID:25849773UniProtPMID:17322308|PMID:17581632|PMID:18599441|PMID:25849773
Eif3lChinchillaeukaryotic translation initiation factor 3 complex part_ofISORGD:13178859068941 PMID:17322308ComplexPortalPMID:17322308
Eif3lChinchillafibrillar center located_inISORGD:13178869068941 PMID:11592397MGIPMID:11592397
Eif3lChinchillanucleolus located_inISORGD:13178869068941 PMID:11592397MGIPMID:11592397
Eif3lChinchillanucleoplasm located_inISORGD:13178869068941 PMID:11592397MGIPMID:11592397
Eif3lChinchillasynapse is_active_inISORGD:13178869068941 PMID:25211037SynGOPMID:25211037

Molecular Function
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lChinchillaprotein binding enablesISOUniProtKB:O149019068941 PMID:32814053IntActPMID:32814053
Eif3lChinchillaprotein binding enablesISOPR:P25976|PR:P70700|PR:Q8K2029068941 PMID:11592397MGIPMID:11592397
Eif3lChinchillaprotein binding enablesISOUniProtKB:P19712-PRO_00000380509068941 PMID:24965446AgBasePMID:24965446
Eif3lChinchillaprotein binding enablesISOUniProtKB:Q9UBQ59068941 PMID:16189514, PMID:21516116, PMID:25416956IntActPMID:16189514|PMID:21516116|PMID:25416956
Eif3lChinchillaprotein binding enablesISOUniProtKB:Q6NYC8|UniProtKB:Q9UBQ59068941 PMID:32296183IntActPMID:32296183
Eif3lChinchillaprotein binding enablesISOUniProtKB:P60228|UniProtKB:Q9UBQ59068941 PMID:19748344, PMID:23623729, PMID:28514442IntActPMID:19748344|PMID:23623729|PMID:28514442
Eif3lChinchillaprotein binding enablesISOUniProtKB:P558849068941 PMID:18599441IntActPMID:18599441
Eif3lChinchillaprotein binding enablesISOUniProtKB:Q9Q2G49068941 PMID:22190034IntActPMID:22190034
Eif3lChinchillaprotein binding enablesISOUniProtKB:P55884|UniProtKB:Q9UBQ59068941 PMID:35271311IntActPMID:35271311
Eif3lChinchillaprotein binding enablesISOUniProtKB:P55884|UniProtKB:P60228|UniProtKB:Q9UBQ59068941 PMID:18599441, PMID:33961781IntActPMID:18599441|PMID:33961781
Eif3lChinchillatranslation initiation factor activity contributes_toISORGD:13178859068941 PMID:17581632, PMID:25849773UniProtKBPMID:17581632|PMID:25849773
Eif3lChinchillatranslation initiation factor activity contributes_toISORGD:13178869068941 PMID:17581632UniProtPMID:17581632
1 to 12 of 12 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Eif3lChinchillatranslation initiation pathway  ISORGD:13178859068941 RGDPMID:24499181|REF_RGD_ID:10002776

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074   PMID:30032202  



Eif3l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,220,188 - 24,254,176 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541324,220,188 - 24,250,786 (+)NCBIChiLan1.0ChiLan1.0
EIF3L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,849,419 - 37,889,407 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,848,868 - 37,889,407 (+)EnsemblGRCh38hg38GRCh38
GRCh372238,245,426 - 38,285,414 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,575,316 - 36,614,584 (+)NCBINCBI36Build 36hg18NCBI36
Build 342236,569,869 - 36,609,137NCBI
Celera2222,047,135 - 22,086,399 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,211,745 - 21,251,253 (+)NCBIHuRef
CHM1_12238,204,124 - 38,243,546 (+)NCBICHM1_1
T2T-CHM13v2.02238,311,024 - 38,351,034 (+)NCBIT2T-CHM13v2.0
Eif3l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,959,423 - 78,978,600 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,959,379 - 78,978,605 (+)EnsemblGRCm39 Ensembl
GRCm381579,075,223 - 79,094,400 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,075,179 - 79,094,405 (+)EnsemblGRCm38mm10GRCm38
MGSCv371578,905,653 - 78,924,830 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,902,478 - 78,921,655 (+)NCBIMGSCv36mm8
Celera1581,181,022 - 81,207,760 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Eif3l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,522,222 - 112,544,063 (+)NCBIGRCr8
mRatBN7.27110,652,565 - 110,663,614 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,627,107 - 110,663,614 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,401,442 - 112,412,486 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,624,973 - 114,636,017 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,594,116 - 114,605,149 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,320,547 - 120,331,596 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,320,547 - 120,331,595 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,314,626 - 120,325,675 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,062,697 - 117,073,746 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,087,197 - 117,107,975 (+)NCBI
Celera7106,986,607 - 106,997,655 (+)NCBICelera
Cytogenetic Map7q34NCBI
EIF3L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,709,371 - 47,747,242 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,397,954 - 50,435,602 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,765,793 - 18,803,910 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,595,956 - 36,632,513 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,595,956 - 36,632,513 (+)Ensemblpanpan1.1panPan2
EIF3L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,757,639 - 26,784,908 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,757,639 - 26,785,008 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,712,671 - 26,739,746 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,549,474 - 27,576,553 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,549,474 - 27,577,389 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,272,520 - 27,299,587 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,580,826 - 27,607,864 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,758,191 - 27,785,460 (-)NCBIUU_Cfam_GSD_1.0
Eif3l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,221,647 - 10,264,959 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364923,244,497 - 3,275,342 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF3L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,968,428 - 10,000,092 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,970,013 - 9,996,086 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,465,989 - 7,492,101 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EIF3L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,555,632 - 20,594,335 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045105,189,979 - 105,231,491 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif3l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,034,518 - 10,067,231 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,034,518 - 10,066,449 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSCLAT00000024672   ⟹   ENSCLAP00000024437
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541324,220,188 - 24,254,176 (+)Ensembl
RefSeq Acc Id: XM_005379230   ⟹   XP_005379287
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541324,220,188 - 24,250,786 (+)NCBI
Sequence:
Protein RefSeqs XP_005379287 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000024437
  ENSCLAP00000024437.1
RefSeq Acc Id: XP_005379287   ⟸   XM_005379230
- UniProtKB: A0A8C2W314 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000024437   ⟸   ENSCLAT00000024672
PCI



1 to 13 of 13 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000016779 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000024672 ENTREZGENE
  ENSCLAT00000024672.1 UniProtKB/TrEMBL
InterPro eIF3l UniProtKB/TrEMBL
  PCI_dom UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene Eif3l ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L UniProtKB/TrEMBL
  PTHR13242 UniProtKB/TrEMBL
Pfam Paf67 UniProtKB/TrEMBL
PROSITE PCI UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A8C2W314 ENTREZGENE, UniProtKB/TrEMBL
1 to 13 of 13 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Eif3l  eukaryotic translation initiation factor 3 subunit L    eukaryotic translation initiation factor 3, subunit L  Symbol and/or name change 5135510 APPROVED