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Gene: Bik (BCL2-interacting killer) Rattus norvegicus
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Symbol: Bik
Name: BCL2-interacting killer
Description: Exhibits BH domain binding activity and protein heterodimerization activity. Predicted to be involved in several processes, including apoptotic mitochondrial changes; male gonad development; and positive regulation of cellular component organization. Predicted to localize to the mitochondrial envelope. Human ortholog(s) of this gene implicated in ataxia telangiectasia; breast cancer; colon cancer; and prostate cancer. Orthologous to human BIK (BCL2 interacting killer); PARTICIPATES IN intrinsic apoptotic pathway; INTERACTS WITH (RS)-amphetamine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1H-pyrazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: bcl-2-interacting killer; BCL2-interacting killer (apoptosis-inducing); Bcl2-interacting killer-like; Biklk; Blk
Orthologs:
Homo sapiens (human) : BIK (BCL2 interacting killer)  HGNC  Alliance
Mus musculus (house mouse) : Bik (BCL2-interacting killer)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bik (BCL2 interacting killer)
Pan paniscus (bonobo/pygmy chimpanzee) : BIK (BCL2 interacting killer)
Canis lupus familiaris (dog) : BIK (BCL2 interacting killer)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07124,390,924 - 124,410,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07124,379,878 - 124,399,142 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47121,377,004 - 121,396,609 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17121,411,233 - 121,430,839 (-)NCBI
Celera7110,985,150 - 111,004,412 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

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Disease Annotations
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Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Bik
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621547
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.