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Gene: Bcl2 (BCL2, apoptosis regulator) Rattus norvegicus
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Symbol: Bcl2
Name: BCL2, apoptosis regulator
Description: Exhibits BH domain binding activity and protein heterodimerization activity. Involved in several processes, including response to peptide; response to purine-containing compound; and response to vitamin. Localizes to the cytosol; mitochondrion; and perinuclear region of cytoplasm. Used to study several diseases, including brain disease (multiple); end stage renal failure; gastric ulcer; impotence; and intestinal disease (multiple). Biomarker of several diseases, including brain disease (multiple); eye disease (multiple); hypertension (multiple); intrinsic cardiomyopathy (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); intracranial aneurysm; prostate cancer; and urinary bladder cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator); PARTICIPATES IN intrinsic apoptotic pathway; ceramide signaling pathway; erythropoietin signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-catechin; (+)-pilocarpine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: apoptosis regulator Bcl-2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl-2; Bcl-2alpha; Bcl2-like protein
Orthologs:
Homo sapiens (human) : BCL2 (BCL2 apoptosis regulator)  HGNC  Alliance
Mus musculus (house mouse) : Bcl2 (B cell leukemia/lymphoma 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bcl2 (BCL2 apoptosis regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : BCL2 (BCL2 apoptosis regulator)
Canis lupus familiaris (dog) : BCL2 (BCL2 apoptosis regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcl2 (BCL2 apoptosis regulator)
Sus scrofa (pig) : BCL2 (BCL2 apoptosis regulator)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01326,605,426 - 26,769,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01331,758,213 - 31,920,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41312,730,736 - 12,905,108 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11312,730,735 - 12,905,108 (-)NCBI
Celera1322,550,362 - 22,711,143 (-)NCBICelera
Cytogenetic Map13p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model