Bcl2 (BCL2, apoptosis regulator) - Rat Genome Database

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Gene: Bcl2 (BCL2, apoptosis regulator) Rattus norvegicus
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Symbol: Bcl2
Name: BCL2, apoptosis regulator
RGD ID: 2199
Description: Enables BH domain binding activity. Involved in several processes, including central nervous system development; liver regeneration; and response to monosaccharide. Located in mitochondrial crista and perinuclear region of cytoplasm. Used to study several diseases, including brain ischemia (multiple); end stage renal disease; gastric ulcer; intestinal disease (multiple); and status epilepticus. Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); carcinoma (multiple); intrinsic cardiomyopathy (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); intracranial aneurysm; prostate cancer; and urinary bladder cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator); PARTICIPATES IN intrinsic apoptotic pathway; ceramide signaling pathway; erythropoietin signaling pathway; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (+)-sesamin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: apoptosis regulator Bcl-2; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl-2; Bcl-2alpha; Bcl2-like protein; ENSRNOG00000067693
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Iddm12
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81323,204,464 - 23,366,900 (-)NCBIGRCr8
mRatBN7.21322,689,783 - 22,853,920 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,684,989 - 22,853,743 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1322,684,989 - 22,853,743 (-)NCBImRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1323,013,354 - 23,175,038 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01324,297,817 - 24,459,509 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01322,983,528 - 23,145,223 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01326,605,426 - 26,769,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,605,426 - 26,769,374 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01331,758,213 - 31,920,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41312,730,736 - 12,905,108 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11312,730,735 - 12,905,108 (-)NCBI
Celera1322,550,362 - 22,711,143 (-)NCBICelera
Cytogenetic Map13p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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