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Gene: Bcl2l1 (Bcl2-like 1) Rattus norvegicus
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Symbol: Bcl2l1
Name: Bcl2-like 1
Description: Exhibits several functions, including MDM2/MDM4 family protein binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and transcription factor binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipid; and regulation of synaptic vesicle cycle. Localizes to the cytosol; mitochondrial outer membrane; and presynapse. Colocalizes with the clathrin-coated pit; mitochondrial membrane; and synaptic vesicle membrane. Used to study amyotrophic lateral sclerosis; artery disease (multiple); endometriosis; gastric ulcer; and impotence. Biomarker of acute kidney failure; brain disease (multiple); dilated cardiomyopathy; mental depression; and ocular hypertension. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); leukemia (multiple); and pancreatic cancer. Orthologous to human BCL2L1 (BCL2 like 1); PARTICIPATES IN intrinsic apoptotic pathway; erythropoietin signaling pathway; interleukin-3 signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (R)-carnitine; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; bcl-2-like protein 1; bcl-X; Bcl-xl; bcl2-L-1; Bcl2l; Bclx
Orthologs:
Homo sapiens (human) : BCL2L1 (BCL2 like 1)  HGNC  Alliance
Mus musculus (house mouse) : Bcl2l1 (BCL2-like 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bcl2l1 (BCL2 like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : BCL2L1 (BCL2 like 1)
Canis lupus familiaris (dog) : BCL2L1 (BCL2 like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcl2l1 (BCL2 like 1)
Sus scrofa (pig) : BCL2L1 (BCL2 like 1)
more info ...
Related Pseudogenes: Bcl2l1-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03148,259,594 - 148,314,191 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03154,662,586 - 154,716,802 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,129,087 - 143,180,199 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13143,082,602 - 143,084,431 (-)NCBI
Celera3140,002,906 - 140,053,959 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences