Bcl2l1 (Bcl2-like 1) - Rat Genome Database

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Gene: Bcl2l1 (Bcl2-like 1) Rattus norvegicus
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Symbol: Bcl2l1
Name: Bcl2-like 1
RGD ID: 2200
Description: Enables several functions, including GTPase binding activity; MDM2/MDM4 family protein binding activity; and cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in several processes, including cellular response to cytokine stimulus; cellular response to hormone stimulus; and positive regulation of transport. Located in mitochondrial outer membrane and presynapse. Colocalizes with clathrin-coated pit; mitochondrial membrane; and synaptic vesicle membrane. Used to study amyotrophic lateral sclerosis; artery disease (multiple); endometriosis; gastric ulcer; and impotence. Biomarker of several diseases, including acute kidney failure; brain ischemia; hepatocellular carcinoma; ocular hypertension; and status epilepticus. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); leukemia (multiple); and pancreatic cancer. Orthologous to human BCL2L1 (BCL2 like 1); PARTICIPATES IN intrinsic apoptotic pathway; erythropoietin signaling pathway; interleukin-3 signaling pathway; INTERACTS WITH (R)-carnitine; (R)-lipoic acid; (R)-noradrenaline.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; bcl-2-like protein 1; bcl-X; Bcl-xl; bcl2-L-1; Bcl2l; Bclx
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Bcl2l1-ps1  
Candidate Gene For: Eau4
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,713,777 - 161,764,844 (-)NCBIGRCr8
mRatBN7.23141,253,508 - 141,304,582 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3141,253,523 - 141,303,479 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3145,158,456 - 145,209,456 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,742,281 - 153,793,281 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,482,052 - 151,532,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03148,259,594 - 148,314,191 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,259,596 - 148,313,810 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,662,586 - 154,716,802 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,129,087 - 143,180,199 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13143,082,602 - 143,084,431 (-)NCBI
Celera3140,002,906 - 140,053,959 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (IEP)
acute kidney failure  (IEP)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenoma  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (IMP,ISO)
amyotrophic lateral sclerosis type 1  (ISO)
B-lymphoblastic leukemia/lymphoma  (ISO)
Brain Hypoxia-Ischemia  (IDA)
brain ischemia  (IEP)
breast cancer  (ISO)
breast carcinoma  (ISO)
Breast Neoplasms  (ISO)
carcinoma  (ISO)
Cerebral Hemorrhage  (ISO)
cervical cancer  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
colorectal adenocarcinoma  (ISO)
cryptorchidism  (ISO)
depressive disorder  (IEP)
dilated cardiomyopathy  (IEP)
endometrial cancer  (ISO)
endometriosis  (IDA)
Experimental Diabetes Mellitus  (IDA,ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Mammary Neoplasms  (IDA)
gastric ulcer  (IDA)
genetic disease  (ISO)
Head and Neck Neoplasms  (ISO)
Hearing Loss  (ISO)
hematopoietic system disease  (ISO)
Hemorrhagic Shock  (IEP)
hepatocellular carcinoma  (IEP,ISO)
hereditary breast ovarian cancer syndrome  (ISO)
impotence  (IDA,ISO)
leiomyoma  (ISO)
liver disease  (ISO)
Liver Reperfusion Injury  (IEP)
Lung Neoplasms  (ISO)
lymphoid leukemia  (ISO)
melanoma  (ISO)
multiple myeloma  (ISO)
myocardial infarction  (IMP,ISO)
Myocardial Reperfusion Injury  (IDA)
nephroblastoma  (ISO)
ocular hypertension  (IEP)
oral squamous cell carcinoma  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
plasma cell neoplasm  (ISO)
polycythemia vera  (ISO)
prostate carcinoma  (ISO)
pulmonary hypertension  (IDA)
renal cell carcinoma  (ISO)
Retina Reperfusion Injury  (IEP)
status epilepticus  (IEP)
stomach cancer  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
toxic encephalopathy  (ISO)
transitional cell carcinoma  (ISO)
type 2 diabetes mellitus  (ISO)
urinary bladder cancer  (ISO)
uterus interstitial leiomyoma  (ISO)
Viral Bronchiolitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-epicatechin-3-O-gallate  (ISO)
(+)-Tetrandrine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(20R)-protopanaxadiol  (ISO)
(R)-carnitine  (EXP)
(R)-lipoic acid  (EXP)
(R)-noradrenaline  (EXP)
(R)-salsolinol  (EXP)
(R,R,R)-alpha-tocopherol  (EXP)
(S)-amphetamine  (EXP,ISO)
(S)-colchicine  (EXP)
(S)-naringenin  (ISO)
(S)-nicotine  (ISO)
1'-acetoxychavicol acetate  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,3-dinitrobenzene  (EXP,ISO)
1,3-Dinitropyrene  (ISO)
1-bromopropane  (EXP,ISO)
1-nitropyrene  (ISO)
10-Hydroxycamptothecin  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dichloroindophenol  (ISO)
2-acetamidofluorene  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-deoxy-D-glucose  (ISO)
2-ethoxyethanol  (EXP)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-methoxy-17beta-estradiol  (ISO)
2-methoxyethanol  (EXP)
2-palmitoylglycerol  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,3'-diindolylmethane  (ISO)
3,4-Methylenedioxyamphetamine  (EXP)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3,7-dihydropurine-6-thione  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (ISO)
3-nitropropanoic acid  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4,5,6,7-TETRABROMOBENZOTRIAZOLE  (ISO)
4-Aminobenzamide  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitro-m-cresol  (ISO)
4-nitrophenol  (ISO)
4-nonylphenol  (EXP)
4-vinylcyclohexene dioxide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (EXP,ISO)
5-Hydroxycapric acid  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP,ISO)
6-oxocampestanol  (ISO)
7,8-diacetoxy-4-methylcoumarin  (ISO)
8-OH-DPAT  (ISO)
9,10-anthraquinone  (ISO)
9-Methoxycamptothecin  (ISO)
[6]-Shogaol  (ISO)
ABT-737  (ISO)
acetochlor  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (EXP)
acrylonitrile  (ISO)
actinomycin D  (ISO)
adenosine  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
AH23848  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP)
alginic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
allicin  (ISO)
alloxan  (EXP)
alpha-Solamarine  (ISO)
alpha-Zearalanol  (ISO)
aluminium atom  (ISO)
aluminium oxide  (ISO)
aluminium(0)  (ISO)
alvocidib  (ISO)
amino acid  (ISO)
ammonium chloride  (EXP,ISO)
amosite asbestos  (ISO)
amphibole asbestos  (ISO)
amsacrine  (ISO)
anthocyanin  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
ANTIMYCIN  (ISO)
antirheumatic drug  (ISO)
Antrocin  (ISO)
AP20187  (ISO)
apigenin  (EXP)
apocynin  (ISO)
arachidonic acid  (ISO)
arecoline  (EXP)
aripiprazole  (ISO)
arjunolic acid  (EXP)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (EXP,ISO)
atazanavir sulfate  (ISO)
Atranorin  (ISO)
atrazine  (EXP,ISO)
Auriculasin  (ISO)
azadirachtin A  (ISO)
azathioprine  (ISO)
azilsartan  (ISO)
Bay-K-8644  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[a]pyrene-7,8-diol  (ISO)
benzo[b]fluoranthene  (ISO)
benzophenanthridine  (ISO)
benzothiazoles  (ISO)
Berbamine  (ISO)
berberine  (ISO)
beta-D-glucan  (ISO)
beta-D-glucosamine  (ISO)
Beta-Solamarine  (ISO)
bicalutamide  (ISO)
bilirubin IXalpha  (ISO)
biochanin A  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
boric acid  (ISO)
bortezomib  (ISO)
brassinin  (ISO)
brassinolide  (ISO)
Bromoenol lactone  (EXP)
Brusatol  (ISO)
buta-1,3-diene  (ISO)
butein  (ISO)
Butylparaben  (ISO)
C60 fullerene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cafestol  (ISO)
caffeine  (ISO)
Calcimycin  (EXP)
calciol  (ISO)
calcitriol  (EXP,ISO)
calyculin a  (ISO)
camalexin  (ISO)
camptothecin  (EXP,ISO)
Candesartan cilexetil  (EXP)
cannabidiol  (ISO)
cannabigerol  (ISO)
capillarisin  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
carboplatin  (EXP,ISO)
carmustine  (EXP,ISO)
carvedilol  (EXP)
casticin  (ISO)
cefaloridine  (EXP)
celecoxib  (ISO)
cetrorelix  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (ISO)
chloroquine  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (ISO)
cholesterol  (ISO)
choline  (EXP)
chromium(6+)  (EXP,ISO)
chrysazin  (ISO)
chrysin  (EXP)
chrysin 5,7-dimethyl ether  (EXP)
ciguatoxin CTX1B  (ISO)
Cirsimarin  (ISO)
cisplatin  (EXP,ISO)
citric acid  (ISO)
Clivoline  (ISO)
clofarabine  (ISO)
clofibrate  (ISO)
clonidine  (EXP)
clonidine (amino form)  (EXP)
clonidine (imino form)  (EXP)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP,ISO)
coenzyme Q10  (EXP)
colistin  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
cordycepin  (ISO)
corticosterone  (EXP)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (ISO)
cucurbitacin E  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cypermethrin  (EXP,ISO)
cytarabine  (ISO)
D-glucose  (EXP)
dactolisib  (ISO)
daidzein  (ISO)
deguelin  (ISO)
dehydroepiandrosterone  (EXP)
dehydroepiandrosterone sulfate  (EXP)
delphinidin  (ISO)
demethoxycurcumin  (ISO)
demethoxyfumitremorgin C  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
depsipeptide  (ISO)
Destruxin B  (ISO)
dexamethasone  (EXP,ISO)
dexmedetomidine  (EXP)
dextromethorphan  (EXP)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP)
diazoxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
diclofenac  (ISO)
Dictamnine  (ISO)
dieldrin  (EXP)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (ISO)
dioscin  (ISO)
diosgenin  (ISO)
dioxygen  (EXP,ISO)
dipyridamole  (ISO)
diquat  (ISO)
dizocilpine maleate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
elemental selenium  (EXP,ISO)
endosulfan  (EXP,ISO)
entinostat  (ISO)
erdosteine  (ISO)
Erionite  (ISO)
esculetin  (ISO)
etacrynic acid  (ISO)
ethanol  (EXP)
etoposide  (ISO)
eugenol  (ISO)
Evodiamine  (ISO)
farrerol  (ISO)
fenofibrate  (ISO)
fenvalerate  (ISO)
finasteride  (EXP)
fisetin  (ISO)
flavonoids  (EXP,ISO)
flubendazole  (ISO)
flufenoxuron  (ISO)
fluoxetine  (EXP)
flutamide  (ISO)
folic acid  (ISO)
fructose  (EXP)
fucoxanthin  (ISO)
fulvestrant  (EXP)
furan  (EXP)
Fusarenone X  (ISO)
galangin  (ISO)
gallein  (EXP)
gamma-aminobutyric acid  (EXP)
gamma-hexachlorocyclohexane  (EXP)
gamma-tocopherol  (ISO)
Gastrodin  (ISO)
geldanamycin  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (EXP,ISO)
geraniol  (EXP)
Ginkgoic acid  (ISO)
Ginkgolide C  (EXP)
ginsenoside Re  (ISO)
glucose  (EXP)
glutathione  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
gossypin  (ISO)
gossypol  (ISO)
GW 6471  (ISO)
Gyrophoric acid  (ISO)
haloperidol  (EXP)
homoeriodictyol  (ISO)
hyaluronic acid  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
hydroxamic acid  (ISO)
hydroxyurea  (EXP)
ibrutinib  (ISO)
ibuprofen  (ISO)
idelalisib  (ISO)
Idoxifene  (EXP)
Ilimaquinone  (ISO)
indirubin-3'-monoxime  (ISO)
indole-3-methanol  (ISO)
indometacin  (EXP,ISO)
inulin  (ISO)
irinotecan  (ISO)
iron atom  (ISO)
iron dextran  (ISO)
iron(0)  (ISO)
isoflavones  (ISO)
isoflurane  (EXP)
Isoliensinine  (ISO)
isoliquiritigenin  (ISO)
isopimaric acid  (ISO)
isoprenaline  (EXP,ISO)
isorhamnetin  (ISO)
isotretinoin  (ISO)
kaempferol  (ISO)
kurarinol  (ISO)
L-ascorbic acid  (EXP)
L-methionine  (EXP)
lactacystin  (ISO)
lead diacetate  (ISO)
lead(0)  (EXP)
leptomycin B  (ISO)
linalool  (ISO)
lipoic acid  (EXP)
lipopolysaccharide  (EXP,ISO)
lithium chloride  (ISO)
lithocholic acid  (ISO)
lonafarnib  (ISO)
lonidamine  (ISO)
lovastatin  (EXP)
lutein  (ISO)
luteolin  (ISO)
Luteolin 7-methyl ether  (EXP)
luteolin 7-O-beta-D-glucoside  (ISO)
LY294002  (EXP,ISO)
maneb  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP)
mangiferin  (ISO)
melamine  (ISO)
melatonin  (EXP,ISO)
mercaptopurine  (ISO)
mercury dichloride  (EXP)
metformin  (EXP,ISO)
methamphetamine  (EXP,ISO)
methidathion  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (EXP)
methylmercury(1+)  (EXP)
methylparaben  (ISO)
metoprolol  (EXP)
mevalonic acid  (EXP)
mifepristone  (EXP)
mitomycin C  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotaline  (ISO)
morin  (EXP,ISO)
morphine  (EXP)
morusin  (ISO)
Myrtucommulone A  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N,N-dimethylformamide  (EXP,ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-Acetyl-S-(1,2-dichlorovinyl)-cysteine  (ISO)
N-acetylsphingosine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
nefazodone  (ISO)
nickel dichloride  (EXP,ISO)
nickel subsulfide  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
nicotine  (ISO)
nitric oxide  (EXP,ISO)
nitrobenzenes  (EXP)
nitrofen  (ISO)
nitroprusside  (EXP)
Nodularin  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
NORCANTHARIDIN  (ISO)
NSC 23766  (ISO)
Nutlin-3  (ISO)
ochratoxin A  (EXP,ISO)
oleanolic acid  (ISO)
oltipraz  (ISO)
ouabain  (ISO)
oxaliplatin  (ISO)
oxybenzone  (EXP)
oxybuprocaine  (ISO)
ozone  (EXP,ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (EXP)
paricalcitol  (ISO)
parthenolide  (ISO)
PCB138  (ISO)
Pentoxifylline  (ISO)
pepstatin A  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
perindopril  (EXP)
pevonedistat  (ISO)
PHA-665752  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
phenol red  (ISO)
phenylephrine  (EXP,ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
phloretin  (ISO)
phlorizin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phytoestrogen  (ISO)
picoxystrobin  (ISO)
picrotoxin  (EXP)
pirinixic acid  (ISO)
PK-11195  (ISO)
platycodin D  (ISO)
plumbagin  (ISO)
potassium dichromate  (EXP)
Pranoprofen  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (EXP)
progesterone  (EXP)
promethazine  (ISO)
propiconazole  (ISO)
propofol  (EXP)
propylparaben  (ISO)
prostaglandin E2  (EXP)
protein kinase inhibitor  (ISO)
Psymberin  (ISO)
pterostilbene  (ISO)
purine-6-thiol  (ISO)
puromycin  (ISO)
pyrethrins  (ISO)
pyrrolidine dithiocarbamate  (EXP,ISO)
quercetin  (EXP,ISO)
raloxifene  (ISO)
reactive oxygen species  (ISO)
Rebamipide  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
ritonavir  (ISO)
Ro 31-8220  (EXP)
romidepsin  (ISO)
rotenone  (ISO)
rottlerin  (ISO)
rubimaillin  (ISO)
rucaparib  (ISO)
rutin  (EXP)
Salinomycin  (ISO)
Salvianolic acid A  (EXP,ISO)
salvianolic acid B  (EXP)
sarin  (ISO)
SB 203580  (EXP)
SB 431542  (ISO)
SCH772984  (ISO)
scutellarin  (EXP)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenium atom  (EXP,ISO)
senecionine  (ISO)
sevoflurane  (ISO)
sildenafil citrate  (ISO)
silicon dioxide  (ISO)
simazine  (ISO)
simvastatin  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium chromate  (ISO)
sodium dichromate  (EXP,ISO)
sorafenib  (ISO)
spironolactone  (EXP)
stattic  (ISO)
staurosporine  (EXP,ISO)
stavudine  (EXP)
streptozocin  (EXP,ISO)
styrene  (ISO)
styrene oxide  (ISO)
succimer  (ISO)
succinic acid  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sulindac sulfide  (ISO)
Sunset Yellow FCF  (ISO)
surfactin  (ISO)
surfactin C  (ISO)
T-2 toxin  (EXP,ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
tanespimycin  (ISO)
tartrazine  (ISO)
taurine  (EXP)
tauroursodeoxycholic acid  (EXP)
Tautomycin  (ISO)
temozolomide  (ISO)
TEMPO  (EXP,ISO)
teriflunomide  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetramethylpyrazine  (EXP,ISO)
thalidomide  (ISO)
thapsigargin  (EXP,ISO)
thioacetamide  (EXP)
thiostrepton  (ISO)
Thiotepa  (ISO)
thymol  (EXP)
thymol sulfate(1-)  (EXP)
thymoquinone  (ISO)
tin(II) chloride (anhydrous)  (EXP)
titanium dioxide  (ISO)
tocopherol  (ISO)
Tomentosin  (ISO)
toosendanin  (ISO)
topotecan  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (EXP,ISO)
triclosan  (ISO)
trimethyltin  (ISO)
Triptolide  (EXP,ISO)
triptonide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
Tylophorine  (ISO)
tyrphostin AG 1478  (EXP)
valproic acid  (ISO)
veliparib  (ISO)
vemurafenib  (ISO)
venetoclax  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (EXP,ISO)
vorinostat  (EXP,ISO)
wortmannin  (ISO)
Xanthorrhizol  (ISO)
zerumbone  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (ISO)
zinc protoporphyrin  (EXP,ISO)
zinc pyrithione  (ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)
zoledronic acid  (ISO)
zolmitriptan  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (ISO)
apoptotic process in bone marrow cell  (ISO)
cellular response to alkaloid  (ISO)
cellular response to amino acid stimulus  (ISO)
cellular response to astaxanthin  (IEP)
cellular response to cAMP  (IEP)
cellular response to dexamethasone stimulus  (IEP)
cellular response to erythropoietin  (IEP)
cellular response to gamma radiation  (ISO)
cellular response to hypoxia  (IEP)
cellular response to interleukin-1  (IEP)
cellular response to nitric oxide  (IEP)
cellular response to prolactin  (IEP)
cellular response to tumor necrosis factor  (IEP)
cellular response to xenobiotic stimulus  (IEP)
cerebral cortex development  (IEP)
dendritic cell apoptotic process  (ISO)
dendritic cell proliferation  (ISO)
ectopic germ cell programmed cell death  (ISO)
endocytosis  (IEA)
epithelial cell proliferation  (ISO)
extrinsic apoptotic signaling pathway in absence of ligand  (IBA,IEA,ISO)
fertilization  (ISO)
germ cell development  (ISO)
gonad development  (IEA)
hepatocyte apoptotic process  (ISO)
in utero embryonic development  (ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (IBA,IEA,ISO)
male gonad development  (ISO)
mitochondrion organization  (ISO)
negative regulation of anoikis  (ISO)
negative regulation of apoptotic process  (IDA,IMP,ISO)
negative regulation of dendritic cell apoptotic process  (ISO)
negative regulation of developmental process  (ISO)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  (ISO,ISS)
negative regulation of execution phase of apoptosis  (ISO,ISS)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (ISO)
negative regulation of intrinsic apoptotic signaling pathway  (IBA,IEA,ISO)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  (ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of protein localization to plasma membrane  (ISO)
negative regulation of release of cytochrome c from mitochondria  (ISO)
negative regulation of reproductive process  (ISO)
neuron apoptotic process  (ISO)
ovarian follicle development  (IMP,ISO)
positive regulation of apoptotic process  (IMP,ISO)
positive regulation of ATP biosynthetic process  (IMP)
positive regulation of mononuclear cell proliferation  (ISO)
positive regulation of synaptic vesicle clustering  (IMP)
positive regulation of synaptic vesicle endocytosis  (IMP)
positive regulation of synaptic vesicle exocytosis  (IMP)
regulation of apoptotic process  (IDA)
regulation of cytokinesis  (ISO,ISS)
regulation of growth  (ISO)
regulation of long-term synaptic depression  (IMP)
regulation of mitochondrial membrane permeability  (ISO)
regulation of mitochondrial membrane potential  (ISO)
release of cytochrome c from mitochondria  (ISO)
response to cycloheximide  (ISO)
response to cytokine  (ISO)
response to electrical stimulus  (IEP)
response to endoplasmic reticulum stress  (IEP)
response to erythropoietin  (IEP)
response to hydrogen peroxide  (IEP)
response to hypoxia  (IEP)
response to inorganic substance  (IEP)
response to ischemia  (IDA)
response to lead ion  (IEP)
response to lipopolysaccharide  (IEP)
response to organic cyclic compound  (IEP)
response to organonitrogen compound  (IEP)
response to oxidative stress  (IEP)
response to peptide hormone  (IEP)
response to radiation  (ISO)
response to virus  (ISO)
response to xenobiotic stimulus  (IEP)
spermatogenesis  (ISO)
synaptic vesicle recycling via endosome  (IMP)

Cellular Component

References

References - curated
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98. Venlafaxine modulates depression-induced behaviour and the expression of Bax mRNA and Bcl-xl mRNA in both hippocampus and myocardium. Wang Y, etal., Hum Psychopharmacol. 2011 Mar;26(2):95-101. doi: 10.1002/hup.1177. Epub 2011 Feb 9.
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100. Oxidative stress-induced apoptotic insults to rat osteoblasts are attenuated by nitric oxide pretreatment via GATA-5-involved regulation of Bcl-X L gene expression and protein translocation. Wu GJ, etal., Arch Toxicol. 2016 Apr;90(4):905-16. doi: 10.1007/s00204-015-1491-z. Epub 2015 Mar 1.
101. Loss of anti-apoptotic genes in aging rat crura. Yamanaka M, etal., J Urol. 2002 Nov;168(5):2296-300.
102. Genetic redox preconditioning differentially modulates AP-1 and NF kappa B responses following cardiac ischemia/reperfusion injury and protects against necrosis and apoptosis. Yang J, etal., Mol Ther. 2003 Mar;7(3):341-53.
103. Rho-kinase-dependent pathway mediates the hepatoprotective effects of sorafenib against ischemia/reperfusion liver injury in rats with nonalcoholic steatohepatitis. Yang YY, etal., Liver Transpl. 2012 Nov;18(11):1371-83. doi: 10.1002/lt.23520.
104. Silencing of FGFR4 could influence the biological features of gastric cancer cells and its therapeutic value in gastric cancer. Ye Y, etal., Tumour Biol. 2016 Mar;37(3):3185-95. doi: 10.1007/s13277-015-4100-0. Epub 2015 Oct 2.
105. Delayed apoptosis by neutrophils from COPD patients is associated with altered Bak, Bcl-xl, and Mcl-1 mRNA expression. Zhang J, etal., Diagn Pathol. 2012 Jun 11;7:65. doi: 10.1186/1746-1596-7-65.
106. Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma. Zhuang L, etal., Mod Pathol. 2007 Apr;20(4):416-26.
Additional References at PubMed
PMID:7607090   PMID:7650367   PMID:7650488   PMID:7753802   PMID:7828536   PMID:7834748   PMID:8625820   PMID:8798158   PMID:8798452   PMID:8918887   PMID:9096145   PMID:9176392  
PMID:9184696   PMID:9346936   PMID:9388232   PMID:9843949   PMID:9867803   PMID:10618441   PMID:10894153   PMID:11146504   PMID:11150333   PMID:11717309   PMID:11721745   PMID:11980919  
PMID:12011449   PMID:12115603   PMID:12477932   PMID:12496370   PMID:12667443   PMID:12785016   PMID:12931191   PMID:12967636   PMID:14517295   PMID:14532118   PMID:14651853   PMID:14676192  
PMID:14999001   PMID:15006356   PMID:15121179   PMID:15131699   PMID:15149850   PMID:15231831   PMID:15545017   PMID:15574729   PMID:15596800   PMID:15720830   PMID:15901672   PMID:16085054  
PMID:16111822   PMID:16133871   PMID:16205321   PMID:16301318   PMID:16428456   PMID:16603546   PMID:16608847   PMID:16723699   PMID:16815550   PMID:17052454   PMID:17073802   PMID:17132701  
PMID:17267035   PMID:17289999   PMID:17428862   PMID:17600519   PMID:17644076   PMID:18053090   PMID:18163394   PMID:18221257   PMID:18347331   PMID:18497705   PMID:18923682   PMID:18980715  
PMID:19082728   PMID:19339209   PMID:19767770   PMID:19862336   PMID:19885947   PMID:19938943   PMID:20106970   PMID:20457187   PMID:20499358   PMID:20671748   PMID:20673843   PMID:21041309  
PMID:21199865   PMID:21567405   PMID:21639858   PMID:21710144   PMID:21740920   PMID:21840391   PMID:21856303   PMID:21861389   PMID:21863631   PMID:21926988   PMID:22292018   PMID:22294442  
PMID:22366758   PMID:22424444   PMID:22871113   PMID:23015448   PMID:23530063   PMID:23731686   PMID:24096434   PMID:24326522   PMID:24444606   PMID:24787232   PMID:25681439   PMID:26109654  
PMID:26254736   PMID:26582200   PMID:27815660   PMID:27830683   PMID:28320275   PMID:28320276   PMID:28478796   PMID:28597245   PMID:29507230   PMID:33340237   PMID:36982731  


Genomics

Comparative Map Data
Bcl2l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,713,777 - 161,764,844 (-)NCBIGRCr8
mRatBN7.23141,253,508 - 141,304,582 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3141,253,523 - 141,303,479 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3145,158,456 - 145,209,456 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,742,281 - 153,793,281 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,482,052 - 151,532,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03148,259,594 - 148,314,191 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,259,596 - 148,313,810 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,662,586 - 154,716,802 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,129,087 - 143,180,199 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13143,082,602 - 143,084,431 (-)NCBI
Celera3140,002,906 - 140,053,959 (-)NCBICelera
Cytogenetic Map3q41NCBI
BCL2L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382031,664,452 - 31,723,963 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2031,664,452 - 31,723,989 (-)EnsemblGRCh38hg38GRCh38
GRCh372030,252,255 - 30,311,766 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362029,715,922 - 29,774,317 (-)NCBINCBI36Build 36hg18NCBI36
Build 342029,715,923 - 29,774,317NCBI
Celera2027,008,611 - 27,067,007 (-)NCBICelera
Cytogenetic Map20q11.21NCBI
HuRef2027,040,965 - 27,099,720 (-)NCBIHuRef
CHM1_12030,156,171 - 30,214,537 (-)NCBICHM1_1
T2T-CHM13v2.02033,388,711 - 33,448,575 (-)NCBIT2T-CHM13v2.0
Bcl2l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392152,600,652 - 152,673,632 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2152,622,588 - 152,673,648 (-)EnsemblGRCm39 Ensembl
GRCm382152,758,732 - 152,833,803 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2152,780,668 - 152,831,728 (-)EnsemblGRCm38mm10GRCm38
MGSCv372152,606,404 - 152,657,418 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362152,472,109 - 152,523,123 (-)NCBIMGSCv36mm8
Celera2158,596,643 - 158,647,694 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map275.41NCBI
Bcl2l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542229,254,216 - 29,308,174 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542229,254,440 - 29,307,104 (+)NCBIChiLan1.0ChiLan1.0
BCL2L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,358,784 - 37,419,063 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12037,351,882 - 37,412,161 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02027,955,688 - 28,015,950 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12029,088,055 - 29,147,066 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2029,088,055 - 29,146,585 (-)Ensemblpanpan1.1panPan2
BCL2L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12421,145,214 - 21,209,425 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2421,145,215 - 21,196,355 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2420,792,367 - 20,843,516 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02421,828,012 - 21,896,118 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2421,831,867 - 21,896,046 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12421,109,822 - 21,160,959 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02421,214,910 - 21,266,211 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02421,645,527 - 21,696,882 (-)NCBIUU_Cfam_GSD_1.0
Bcl2l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640170,222,682 - 170,275,934 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648518,654,046 - 18,707,324 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL2L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1735,366,143 - 35,414,694 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11735,366,139 - 35,415,798 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21740,303,991 - 40,304,598 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BCL2L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1236,059,024 - 36,118,332 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl236,058,919 - 36,116,470 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605090,796,126 - 90,855,484 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcl2l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624741789,355 - 839,507 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624741788,445 - 838,513 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bcl2l1
125 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:464
Count of miRNA genes:238
Interacting mature miRNAs:299
Transcripts:ENSRNOT00000010762, ENSRNOT00000024954, ENSRNOT00000047416
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3140069424146976080Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat

Markers in Region
D3Got106  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23141,282,112 - 141,282,245 (+)MAPPERmRatBN7.2
Rnor_6.03148,291,418 - 148,291,550NCBIRnor6.0
Rnor_5.03154,694,410 - 154,694,542UniSTSRnor5.0
RGSC_v3.43143,157,804 - 143,157,937RGDRGSC3.4
RGSC_v3.43143,157,805 - 143,157,937UniSTSRGSC3.4
RGSC_v3.13143,063,427 - 143,063,559RGD
Celera3140,031,529 - 140,031,661UniSTS
RH 3.4 Map31253.4UniSTS
RH 3.4 Map31253.4RGD
RH 2.0 Map3852.1RGD
Cytogenetic Map3q41.2UniSTS
BM383754  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23141,254,537 - 141,254,715 (+)MAPPERmRatBN7.2
mRatBN7.21157,043,338 - 157,043,516 (+)MAPPERmRatBN7.2
Rnor_6.01167,764,587 - 167,764,764NCBIRnor6.0
Rnor_6.03148,260,624 - 148,260,801NCBIRnor6.0
Rnor_5.03154,663,616 - 154,663,793UniSTSRnor5.0
Rnor_5.01173,950,019 - 173,950,196UniSTSRnor5.0
RGSC_v3.41160,253,614 - 160,253,791UniSTSRGSC3.4
RGSC_v3.43143,130,117 - 143,130,294UniSTSRGSC3.4
Celera3140,003,936 - 140,004,113UniSTS
Celera1155,108,435 - 155,108,612UniSTS
RH 3.4 Map11288.3UniSTS
Cytogenetic Map3q41.2UniSTS
Cytogenetic Map1q32UniSTS
PMC196230P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21157,043,771 - 157,044,307 (+)MAPPERmRatBN7.2
Rnor_6.01167,765,020 - 167,765,555NCBIRnor6.0
Rnor_5.01173,950,452 - 173,950,987UniSTSRnor5.0
RGSC_v3.41160,254,047 - 160,254,582UniSTSRGSC3.4
Celera1155,108,868 - 155,109,403UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3q41.2UniSTS
PMC316415P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21157,043,795 - 157,044,019 (+)MAPPERmRatBN7.2
Rnor_6.01167,765,044 - 167,765,267NCBIRnor6.0
Rnor_5.01173,950,476 - 173,950,699UniSTSRnor5.0
RGSC_v3.41160,254,071 - 160,254,294UniSTSRGSC3.4
Celera1155,108,892 - 155,109,115UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3q41.2UniSTS
PMC123054P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21157,043,981 - 157,044,400 (+)MAPPERmRatBN7.2
mRatBN7.23141,302,549 - 141,302,968 (+)MAPPERmRatBN7.2
Rnor_6.03148,311,851 - 148,312,269NCBIRnor6.0
Rnor_6.01167,765,230 - 167,765,648NCBIRnor6.0
Rnor_5.03154,714,843 - 154,715,261UniSTSRnor5.0
Rnor_5.01173,950,662 - 173,951,080UniSTSRnor5.0
RGSC_v3.41160,254,257 - 160,254,675UniSTSRGSC3.4
RGSC_v3.43143,178,240 - 143,178,658UniSTSRGSC3.4
Celera3140,052,000 - 140,052,418UniSTS
Celera1155,109,078 - 155,109,496UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3q41.2UniSTS
PMC20354P5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23141,302,370 - 141,302,627 (+)MAPPERmRatBN7.2
Rnor_6.03148,311,672 - 148,311,928NCBIRnor6.0
Rnor_5.03154,714,664 - 154,714,920UniSTSRnor5.0
RGSC_v3.43143,178,061 - 143,178,317UniSTSRGSC3.4
Celera3140,051,821 - 140,052,077UniSTS
Cytogenetic Map3q41.2UniSTS
PMC262691P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23141,302,331 - 141,302,513 (+)MAPPERmRatBN7.2
Rnor_6.03148,311,633 - 148,311,814NCBIRnor6.0
Rnor_5.03154,714,625 - 154,714,806UniSTSRnor5.0
RGSC_v3.43143,178,022 - 143,178,203UniSTSRGSC3.4
Celera3140,051,782 - 140,051,963UniSTS
Cytogenetic Map3q41.2UniSTS
UniSTS:224427  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21157,043,475 - 157,043,629 (+)MAPPERmRatBN7.2
mRatBN7.23141,254,674 - 141,254,828 (+)MAPPERmRatBN7.2
Rnor_6.01167,764,724 - 167,764,877NCBIRnor6.0
Rnor_6.03148,260,761 - 148,260,914NCBIRnor6.0
Rnor_5.03154,663,753 - 154,663,906UniSTSRnor5.0
Rnor_5.01173,950,156 - 173,950,309UniSTSRnor5.0
RGSC_v3.41160,253,751 - 160,253,904UniSTSRGSC3.4
RGSC_v3.43143,130,254 - 143,130,407UniSTSRGSC3.4
Celera3140,004,073 - 140,004,226UniSTS
Celera1155,108,572 - 155,108,725UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3q41.2UniSTS
Bcl2l  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21157,043,768 - 157,044,343 (+)MAPPERmRatBN7.2
Rnor_6.01167,765,017 - 167,765,591NCBIRnor6.0
Rnor_5.01173,950,449 - 173,951,023UniSTSRnor5.0
RGSC_v3.41160,254,044 - 160,254,618UniSTSRGSC3.4
Celera1155,108,865 - 155,109,439UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3q41.2UniSTS
Bcl2l1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23141,302,496 - 141,302,847 (+)MAPPERmRatBN7.2
mRatBN7.21157,043,910 - 157,044,279 (+)MAPPERmRatBN7.2
Rnor_6.01167,765,159 - 167,765,527NCBIRnor6.0
Rnor_5.01173,950,591 - 173,950,959UniSTSRnor5.0
Celera1155,109,007 - 155,109,375UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3q41.2UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 35 37 28 19 28 74 35 41 11
Low 1 8 20 13 13 8 11 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001033671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001033672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF136230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF279286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ495801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY141038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S76513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S78284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U10579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U34963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U72349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U72350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X82537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000010762   ⟹   ENSRNOP00000010762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3141,253,523 - 141,303,465 (-)Ensembl
Rnor_6.0 Ensembl3148,259,596 - 148,313,810 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000047416   ⟹   ENSRNOP00000043542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3141,300,833 - 141,303,119 (-)Ensembl
Rnor_6.0 Ensembl3148,310,134 - 148,312,420 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081272   ⟹   ENSRNOP00000071164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3148,310,592 - 148,312,420 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091419   ⟹   ENSRNOP00000069758
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3141,298,581 - 141,303,479 (-)Ensembl
Rnor_6.0 Ensembl3148,310,134 - 148,312,791 (-)Ensembl
RefSeq Acc Id: NM_001033670   ⟹   NP_001028842
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,764,775 (-)NCBI
mRatBN7.23141,253,508 - 141,304,509 (-)NCBI
Rnor_6.03148,259,594 - 148,313,810 (-)NCBI
Rnor_5.03154,662,586 - 154,716,802 (-)NCBI
RGSC_v3.43143,129,087 - 143,180,199 (-)RGD
Celera3140,002,906 - 140,053,959 (-)RGD
Sequence:
RefSeq Acc Id: NM_001033671   ⟹   NP_001028843
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,763,250 (-)NCBI
mRatBN7.23141,253,508 - 141,302,984 (-)NCBI
Rnor_6.03148,259,594 - 148,312,285 (-)NCBI
Rnor_5.03154,662,586 - 154,716,802 (-)NCBI
RGSC_v3.43143,129,087 - 143,180,199 (-)RGD
Celera3140,002,906 - 140,052,434 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001033672   ⟹   NP_001028844
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,761,099 - 161,763,756 (-)NCBI
mRatBN7.23141,300,833 - 141,303,490 (-)NCBI
Rnor_6.03148,310,134 - 148,312,791 (-)NCBI
Rnor_5.03154,662,586 - 154,716,802 (-)NCBI
RGSC_v3.43143,129,087 - 143,180,199 (-)RGD
Celera3140,050,283 - 140,052,940 (-)NCBI
Sequence:
RefSeq Acc Id: NM_031535   ⟹   NP_113723
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,761,099 - 161,763,385 (-)NCBI
mRatBN7.23141,300,833 - 141,303,119 (-)NCBI
Rnor_6.03148,310,134 - 148,312,420 (-)NCBI
Rnor_5.03154,662,586 - 154,716,802 (-)NCBI
RGSC_v3.43143,129,087 - 143,180,199 (-)RGD
Celera3140,050,283 - 140,052,569 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235264   ⟹   XP_006235326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,738,388 - 161,764,844 (-)NCBI
mRatBN7.23141,291,473 - 141,304,582 (-)NCBI
Rnor_6.03148,298,309 - 148,314,191 (-)NCBI
Rnor_5.03154,662,586 - 154,716,802 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235265   ⟹   XP_006235327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,764,808 (-)NCBI
mRatBN7.23141,253,508 - 141,304,131 (-)NCBI
Rnor_6.03148,259,594 - 148,313,460 (-)NCBI
Rnor_5.03154,662,586 - 154,716,802 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591478   ⟹   XP_017446967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,738,388 - 161,764,808 (-)NCBI
mRatBN7.23141,291,473 - 141,304,131 (-)NCBI
Rnor_6.03148,298,309 - 148,313,488 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591479   ⟹   XP_017446968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,738,388 - 161,764,804 (-)NCBI
mRatBN7.23141,291,473 - 141,304,572 (-)NCBI
Rnor_6.03148,298,309 - 148,314,191 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591480   ⟹   XP_017446969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,738,388 - 161,763,514 (-)NCBI
mRatBN7.23141,291,473 - 141,303,196 (-)NCBI
Rnor_6.03148,298,309 - 148,312,537 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039104290   ⟹   XP_038960218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,764,808 (-)NCBI
mRatBN7.23141,253,508 - 141,304,131 (-)NCBI
RefSeq Acc Id: XM_039104291   ⟹   XP_038960219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,763,535 (-)NCBI
mRatBN7.23141,253,508 - 141,303,197 (-)NCBI
RefSeq Acc Id: XM_039104292   ⟹   XP_038960220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,764,808 (-)NCBI
mRatBN7.23141,253,508 - 141,304,131 (-)NCBI
RefSeq Acc Id: XM_063283115   ⟹   XP_063139185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,764,820 (-)NCBI
RefSeq Acc Id: XM_063283116   ⟹   XP_063139186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,763,445 (-)NCBI
RefSeq Acc Id: XM_063283117   ⟹   XP_063139187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,764,808 (-)NCBI
RefSeq Acc Id: XM_063283118   ⟹   XP_063139188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,764,844 (-)NCBI
RefSeq Acc Id: XM_063283119   ⟹   XP_063139189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,763,471 (-)NCBI
RefSeq Acc Id: XM_063283120   ⟹   XP_063139190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,713,777 - 161,764,805 (-)NCBI
RefSeq Acc Id: XR_010064563
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,717,415 - 161,764,808 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001028842 (Get FASTA)   NCBI Sequence Viewer  
  NP_001028843 (Get FASTA)   NCBI Sequence Viewer  
  NP_001028844 (Get FASTA)   NCBI Sequence Viewer  
  NP_113723 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235326 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235327 (Get FASTA)   NCBI Sequence Viewer  
  XP_017446967 (Get FASTA)   NCBI Sequence Viewer  
  XP_017446968 (Get FASTA)   NCBI Sequence Viewer  
  XP_017446969 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960218 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960219 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960220 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139185 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139186 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139187 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139188 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139189 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139190 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA19257 (Get FASTA)   NCBI Sequence Viewer  
  AAA77686 (Get FASTA)   NCBI Sequence Viewer  
  AAB17352 (Get FASTA)   NCBI Sequence Viewer  
  AAB17353 (Get FASTA)   NCBI Sequence Viewer  
  AAC60701 (Get FASTA)   NCBI Sequence Viewer  
  AAC60702 (Get FASTA)   NCBI Sequence Viewer  
  AAD33683 (Get FASTA)   NCBI Sequence Viewer  
  AAF81262 (Get FASTA)   NCBI Sequence Viewer  
  AAH94213 (Get FASTA)   NCBI Sequence Viewer  
  AAN17784 (Get FASTA)   NCBI Sequence Viewer  
  CAA57886 (Get FASTA)   NCBI Sequence Viewer  
  CAA57887 (Get FASTA)   NCBI Sequence Viewer  
  CAD42238 (Get FASTA)   NCBI Sequence Viewer  
  EDL86039 (Get FASTA)   NCBI Sequence Viewer  
  EDL86042 (Get FASTA)   NCBI Sequence Viewer  
  EDL86043 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010762
  ENSRNOP00000010762.4
  ENSRNOP00000024954.1
  ENSRNOP00000043542
  ENSRNOP00000043542.2
  ENSRNOP00000069758
  ENSRNOP00000069758.1
GenBank Protein P53563 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001028842   ⟸   NM_001033670
- Peptide Label: isoform 2
- UniProtKB: Q64087 (UniProtKB/Swiss-Prot),   Q62836 (UniProtKB/Swiss-Prot),   Q62678 (UniProtKB/Swiss-Prot),   Q52KS0 (UniProtKB/Swiss-Prot),   P70614 (UniProtKB/Swiss-Prot),   P70613 (UniProtKB/Swiss-Prot),   Q64128 (UniProtKB/Swiss-Prot),   P53563 (UniProtKB/Swiss-Prot),   A6KHR4 (UniProtKB/TrEMBL),   A6KHR2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001028843   ⟸   NM_001033671
- Peptide Label: isoform 3
- UniProtKB: Q548R7 (UniProtKB/TrEMBL),   E9PU78 (UniProtKB/TrEMBL),   Q9WUI5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001028844   ⟸   NM_001033672
- Peptide Label: isoform 1
- UniProtKB: Q7TS62 (UniProtKB/TrEMBL),   A6KHR6 (UniProtKB/TrEMBL),   A0A0G2JW63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_113723   ⟸   NM_031535
- Peptide Label: isoform 1
- UniProtKB: Q7TS62 (UniProtKB/TrEMBL),   A6KHR6 (UniProtKB/TrEMBL),   A0A0G2JW63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235327   ⟸   XM_006235265
- Peptide Label: isoform X2
- UniProtKB: Q64087 (UniProtKB/Swiss-Prot),   Q62836 (UniProtKB/Swiss-Prot),   Q62678 (UniProtKB/Swiss-Prot),   Q52KS0 (UniProtKB/Swiss-Prot),   P70614 (UniProtKB/Swiss-Prot),   P70613 (UniProtKB/Swiss-Prot),   Q64128 (UniProtKB/Swiss-Prot),   P53563 (UniProtKB/Swiss-Prot),   A6KHR4 (UniProtKB/TrEMBL),   A6KHR2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235326   ⟸   XM_006235264
- Peptide Label: isoform X1
- UniProtKB: Q7TS62 (UniProtKB/TrEMBL),   A6KHR6 (UniProtKB/TrEMBL),   A0A0G2JW63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446968   ⟸   XM_017591479
- Peptide Label: isoform X1
- UniProtKB: Q7TS62 (UniProtKB/TrEMBL),   A6KHR6 (UniProtKB/TrEMBL),   A0A0G2JW63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446967   ⟸   XM_017591478
- Peptide Label: isoform X1
- UniProtKB: Q7TS62 (UniProtKB/TrEMBL),   A6KHR6 (UniProtKB/TrEMBL),   A0A0G2JW63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446969   ⟸   XM_017591480
- Peptide Label: isoform X1
- UniProtKB: Q7TS62 (UniProtKB/TrEMBL),   A6KHR6 (UniProtKB/TrEMBL),   A0A0G2JW63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000043542   ⟸   ENSRNOT00000047416
RefSeq Acc Id: ENSRNOP00000069758   ⟸   ENSRNOT00000091419
RefSeq Acc Id: ENSRNOP00000071164   ⟸   ENSRNOT00000081272
RefSeq Acc Id: ENSRNOP00000010762   ⟸   ENSRNOT00000010762
RefSeq Acc Id: XP_038960220   ⟸   XM_039104292
- Peptide Label: isoform X3
- UniProtKB: Q548R7 (UniProtKB/TrEMBL),   E9PU78 (UniProtKB/TrEMBL),   Q9WUI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960218   ⟸   XM_039104290
- Peptide Label: isoform X2
- UniProtKB: Q64087 (UniProtKB/Swiss-Prot),   Q62836 (UniProtKB/Swiss-Prot),   Q62678 (UniProtKB/Swiss-Prot),   Q52KS0 (UniProtKB/Swiss-Prot),   P70614 (UniProtKB/Swiss-Prot),   P70613 (UniProtKB/Swiss-Prot),   P53563 (UniProtKB/Swiss-Prot),   Q64128 (UniProtKB/Swiss-Prot),   A6KHR4 (UniProtKB/TrEMBL),   A6KHR2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960219   ⟸   XM_039104291
- Peptide Label: isoform X2
- UniProtKB: Q64087 (UniProtKB/Swiss-Prot),   Q62836 (UniProtKB/Swiss-Prot),   Q62678 (UniProtKB/Swiss-Prot),   Q52KS0 (UniProtKB/Swiss-Prot),   P70614 (UniProtKB/Swiss-Prot),   P70613 (UniProtKB/Swiss-Prot),   P53563 (UniProtKB/Swiss-Prot),   Q64128 (UniProtKB/Swiss-Prot),   A6KHR4 (UniProtKB/TrEMBL),   A6KHR2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139188   ⟸   XM_063283118
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063139185   ⟸   XM_063283115
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063139187   ⟸   XM_063283117
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063139190   ⟸   XM_063283120
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063139189   ⟸   XM_063283119
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063139186   ⟸   XM_063283116
- Peptide Label: isoform X2
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P53563-F1-model_v2 AlphaFold P53563 1-233 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692551
Promoter ID:EPDNEW_R3075
Type:initiation region
Name:Bcl2l1_1
Description:Bcl2-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3076  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03148,312,776 - 148,312,836EPDNEW
RGD ID:13692552
Promoter ID:EPDNEW_R3076
Type:initiation region
Name:Bcl2l1_2
Description:Bcl2-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3075  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03148,313,845 - 148,313,905EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2200 AgrOrtholog
BioCyc Gene G2FUF-47248 BioCyc
Ensembl Genes ENSRNOG00000007946 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00000018503 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010762.8 UniProtKB/Swiss-Prot
  ENSRNOT00000024954.3 UniProtKB/TrEMBL
  ENSRNOT00000047416 ENTREZGENE
  ENSRNOT00000047416.4 UniProtKB/TrEMBL
  ENSRNOT00000091419 ENTREZGENE
  ENSRNOT00000091419.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.437.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7314572 IMAGE-MGC_LOAD
InterPro Apop_reg_BclX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl-2_BH1-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl2/BclX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl2_BH1_motif_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl2_BH2_motif_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl2_BH3_motif_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl2_BH4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl2_BH4_motif_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Blc2-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Blc2_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24888 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105402 IMAGE-MGC_LOAD
NCBI Gene 24888 ENTREZGENE
PANTHER PTHR11256 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11256:SF12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Bcl-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bcl2l1 PhenoGen
PRINTS APOPREGBCLX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BCL2FAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BCL2_FAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH4_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH4_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007946 RatGTEx
  ENSRNOG00000018503 RatGTEx
SMART BCL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BH4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56854 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JW63 ENTREZGENE, UniProtKB/TrEMBL
  A6KHR2 ENTREZGENE, UniProtKB/TrEMBL
  A6KHR4 ENTREZGENE, UniProtKB/TrEMBL
  A6KHR6 ENTREZGENE
  B2CL1_RAT UniProtKB/Swiss-Prot
  E9PU78 ENTREZGENE, UniProtKB/TrEMBL
  P53563 ENTREZGENE
  P70613 ENTREZGENE
  P70614 ENTREZGENE
  Q52KS0 ENTREZGENE
  Q548R7 ENTREZGENE, UniProtKB/TrEMBL
  Q62678 ENTREZGENE
  Q62836 ENTREZGENE
  Q64087 ENTREZGENE
  Q64128 ENTREZGENE
  Q7TS62 ENTREZGENE, UniProtKB/TrEMBL
  Q9WUI5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A6KHR6 UniProtKB/TrEMBL
  P70613 UniProtKB/Swiss-Prot
  P70614 UniProtKB/Swiss-Prot
  Q52KS0 UniProtKB/Swiss-Prot
  Q62678 UniProtKB/Swiss-Prot
  Q62836 UniProtKB/Swiss-Prot
  Q64087 UniProtKB/Swiss-Prot
  Q64128 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Bcl2l1  Bcl2-like 1  Bcl2l  B cell lymphoma 2 like  Symbol and Name updated 629477 APPROVED
2002-06-10 Bcl2l  B cell lymphoma 2 like      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the mitochondrial outer membrane 631757
gene_cellular_localization integral membrane protein localized to the mitochondrial membrane and nuclear envelope 628531
gene_expression expressed in the embryonic and adult neurons of the CNS 628531
gene_function anti-apoptotic factor 631757
gene_process involved in protecting cells from apoptosis and in controlling mitochondrial membrane permeability 631757
gene_process prevents neuronal apoptosis by blocking cytochrome c release 628531
gene_process may inhibit staurosporin induced neuronal apoptosis 628531
gene_product member of the anti-apoptotic Bcl-2 family 628531