Maff (MAF bZIP transcription factor F) - Rat Genome Database

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Gene: Maff (MAF bZIP transcription factor F) Rattus norvegicus
Analyze
Symbol: Maff
Name: MAF bZIP transcription factor F
RGD ID: 1309531
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and regulation of epidermal cell differentiation. Predicted to act upstream of or within in utero embryonic development and skeletal muscle cell differentiation. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Orthologous to human MAFF (MAF bZIP transcription factor F); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC366960; transcription factor MafF; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) ; v-maf musculoaponeurotic fibrosarcoma oncogene homolog F; v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,792,787 - 112,804,139 (+)NCBIGRCr8
mRatBN7.27110,912,367 - 110,923,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,912,499 - 110,923,851 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,660,962 - 112,672,336 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,884,496 - 114,895,870 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,853,854 - 114,865,232 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,580,743 - 120,592,095 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,580,743 - 120,592,095 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,572,094 - 120,586,372 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,328,924 - 117,340,276 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,361,699 - 117,373,300 (+)NCBI
Celera7107,245,920 - 107,257,272 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-anisomycin  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(E)-cinnamyl alcohol  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
1-phenyl-1,2-propanedione  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2-butoxyethanol  (ISO)
2-hexenal  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
amiodarone  (ISO)
amphetamine  (EXP)
antimony(0)  (ISO)
antimycin A  (ISO)
arachidonic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atazanavir sulfate  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
azoxystrobin  (ISO)
Bandrowski's base  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[d]isothiazol-3-one  (ISO)
benzyl cinnamate  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
buta-1,3-diene  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
captan  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (ISO)
choline  (ISO)
chromium atom  (ISO)
ciguatoxin CTX1B  (ISO)
cinnamyl alcohol  (ISO)
cisplatin  (ISO)
citral  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
D-glucose  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl maleate  (ISO)
diethyl sulfate  (ISO)
dioxygen  (EXP,ISO)
diphenylcyclopropenone  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
eugenol  (ISO)
fenamidone  (ISO)
fenvalerate  (EXP)
fluoranthene  (ISO)
fluorescein 5-isothiocyanate  (ISO)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (EXP,ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geranial  (ISO)
geraniol  (ISO)
glucose  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glyphosate  (ISO)
Heliotrine  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (ISO)
hydroquinone  (ISO)
hydroxycitronellal  (ISO)
hypochlorous acid  (ISO)
indometacin  (ISO)
iron dichloride  (ISO)
isoeugenol  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
manganese(II) chloride  (EXP)
menadione  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
methamphetamine  (EXP)
methimazole  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methyl non-2-ynoate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
methyltestosterone  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
n-propyl gallate  (ISO)
naphthalene  (EXP)
nefazodone  (ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (ISO)
obeticholic acid  (ISO)
organoselenium compound  (ISO)
oxaliplatin  (EXP)
oxazepam  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
perillyl aldehyde  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phosgene  (ISO)
phthalic anhydride  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
salicylic acid  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
senecionine  (ISO)
Senkirkine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
Soman  (EXP)
sotorasib  (ISO)
sulfadimethoxine  (EXP)
Sunset Yellow FCF  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
tartrazine  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trametinib  (ISO)
trans-isoeugenol  (ISO)
triacsin C  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12490281   PMID:15087497   PMID:22147266   PMID:23332764  


Genomics

Comparative Map Data
Maff
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,792,787 - 112,804,139 (+)NCBIGRCr8
mRatBN7.27110,912,367 - 110,923,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,912,499 - 110,923,851 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,660,962 - 112,672,336 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,884,496 - 114,895,870 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,853,854 - 114,865,232 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,580,743 - 120,592,095 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,580,743 - 120,592,095 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,572,094 - 120,586,372 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,328,924 - 117,340,276 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,361,699 - 117,373,300 (+)NCBI
Celera7107,245,920 - 107,257,272 (+)NCBICelera
Cytogenetic Map7q34NCBI
MAFF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,201,994 - 38,216,511 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,200,767 - 38,216,507 (+)EnsemblGRCh38hg38GRCh38
GRCh372238,598,001 - 38,612,518 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,927,944 - 36,942,460 (+)NCBINCBI36Build 36hg18NCBI36
Build 342236,934,041 - 36,937,012NCBI
Celera2222,402,653 - 22,417,221 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,564,466 - 21,578,860 (+)NCBIHuRef
CHM1_12238,556,960 - 38,571,506 (+)NCBICHM1_1
T2T-CHM13v2.02238,666,346 - 38,680,861 (+)NCBIT2T-CHM13v2.0
Maff
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,230,813 - 79,243,278 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,230,821 - 79,243,276 (+)EnsemblGRCm39 Ensembl
GRCm381579,346,621 - 79,359,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,346,621 - 79,359,076 (+)EnsemblGRCm38mm10GRCm38
MGSCv371579,178,108 - 79,189,506 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,174,933 - 79,186,331 (+)NCBIMGSCv36mm8
Celera1581,467,576 - 81,478,973 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Maff
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541324,494,326 - 24,504,728 (+)NCBIChiLan1.0ChiLan1.0
MAFF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,058,144 - 48,073,103 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,746,702 - 50,764,159 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,114,929 - 19,129,901 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,940,064 - 36,954,989 (+)NCBIpanpan1.1PanPan1.1panPan2
MAFF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,475,478 - 26,486,109 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,476,851 - 26,485,931 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,432,096 - 26,441,384 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,268,184 - 27,277,547 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,268,311 - 27,277,535 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,989,008 - 26,998,285 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,300,235 - 27,309,493 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,477,234 - 27,486,527 (-)NCBIUU_Cfam_GSD_1.0
Maff
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,972,908 - 9,983,641 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,986,813 - 2,987,836 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,983,322 - 2,988,900 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAFF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,683,660 - 9,696,023 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,683,651 - 9,696,128 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,966,177 - 6,978,613 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAFF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,914,271 - 20,927,032 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1920,901,704 - 20,927,174 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045104,842,820 - 104,857,622 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Maff
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247529,771,303 - 9,781,608 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Maff
60 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:164
Count of miRNA genes:118
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000017181
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat

Markers in Region
Maff  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27110,921,661 - 110,922,110 (+)MAPPERmRatBN7.2
Rnor_6.07120,589,906 - 120,590,354NCBIRnor6.0
Rnor_5.07120,582,736 - 120,583,184UniSTSRnor5.0
RGSC_v3.47117,338,087 - 117,338,535UniSTSRGSC3.4
Celera7107,255,083 - 107,255,531UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7 6
Low 3 43 54 38 19 38 8 11 74 35 34 5 8
Below cutoff 3 3 3

Sequence


RefSeq Acc Id: ENSRNOT00000017181   ⟹   ENSRNOP00000017181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7110,912,499 - 110,923,851 (+)Ensembl
Rnor_6.0 Ensembl7120,580,743 - 120,592,095 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094019   ⟹   ENSRNOP00000097254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7110,912,790 - 110,923,851 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116838   ⟹   ENSRNOP00000082038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7110,913,232 - 110,923,851 (+)Ensembl
RefSeq Acc Id: NM_001130573   ⟹   NP_001124045
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,792,787 - 112,804,131 (+)NCBI
mRatBN7.27110,912,367 - 110,923,711 (+)NCBI
Rnor_6.07120,580,743 - 120,592,095 (+)NCBI
Rnor_5.07120,572,094 - 120,586,372 (+)NCBI
RGSC_v3.47117,328,924 - 117,340,276 (+)RGD
Celera7107,245,920 - 107,257,272 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242029   ⟹   XP_006242091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,793,050 - 112,804,139 (+)NCBI
mRatBN7.27110,912,634 - 110,923,711 (+)NCBI
Rnor_6.07120,580,830 - 120,591,955 (+)NCBI
Rnor_5.07120,572,094 - 120,586,372 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001124045 (Get FASTA)   NCBI Sequence Viewer  
  XP_006242091 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM15807 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017181
  ENSRNOP00000017181.4
  ENSRNOP00000082038.1
  ENSRNOP00000097254.1
RefSeq Acc Id: NP_001124045   ⟸   NM_001130573
- UniProtKB: D3ZC87 (UniProtKB/TrEMBL),   A6HSR5 (UniProtKB/TrEMBL),   A0A8I5ZUD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242091   ⟸   XM_006242029
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000017181   ⟸   ENSRNOT00000017181
RefSeq Acc Id: ENSRNOP00000082038   ⟸   ENSRNOT00000116838
RefSeq Acc Id: ENSRNOP00000097254   ⟸   ENSRNOT00000094019
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZC87-F1-model_v2 AlphaFold D3ZC87 1-156 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695480
Promoter ID:EPDNEW_R6005
Type:initiation region
Name:Maff_1
Description:MAF bZIP transcription factor F
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07120,580,662 - 120,580,722EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309531 AgrOrtholog
BioCyc Gene G2FUF-32764 BioCyc
Ensembl Genes ENSRNOG00000012886 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017181 ENTREZGENE
  ENSRNOT00000017181.5 UniProtKB/TrEMBL
  ENSRNOT00000094019.1 UniProtKB/TrEMBL
  ENSRNOT00000116838.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
InterPro bZIP_sf UniProtKB/TrEMBL
  Euk_TF_DNA-bd UniProtKB/TrEMBL
  TF_bZIP UniProtKB/TrEMBL
  TF_Maf UniProtKB/TrEMBL
  Transciption_factor_Maf UniProtKB/TrEMBL
KEGG Report rno:366960 UniProtKB/TrEMBL
NCBI Gene 366960 ENTREZGENE
PANTHER PTHR10129 UniProtKB/TrEMBL
  PTHR10129:SF25 UniProtKB/TrEMBL
Pfam bZIP_Maf UniProtKB/TrEMBL
PhenoGen Maff PhenoGen
PROSITE BZIP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012886 RatGTEx
SMART BRLZ UniProtKB/TrEMBL
Superfamily-SCOP Euk_transcr_DNA UniProtKB/TrEMBL
  SSF57959 UniProtKB/TrEMBL
UniProt A0A8I5ZUD9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AW56_RAT UniProtKB/TrEMBL
  A6HSR5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZC87 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 Maff  MAF bZIP transcription factor F  Maff  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-18 Maff  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F  Maff  v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Maff  v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)  Maff  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Maff  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)   Maff_predicted  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Maff_predicted  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) (predicted)      Symbol and Name status set to approved 70820 APPROVED