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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309531
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Maff
Name: MAF bZIP transcription factor F
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Maffincreases expressionEXP 6480464CTDEstradiol results in increased expression of MAFF mRNAPMID:32145629
Maffdecreases expressionISOMAFF (Homo sapiens)6480464CTDEstradiol results in decreased expression of MAFF mRNAPMID:31646340
Maffincreases expressionISOMAFF (Homo sapiens)6480464CTDEstradiol results in increased expression of MAFF mRNAPMID:19619570 PMID:20106945 PMID:31614463
Maffincreases expressionISOMaff (Mus musculus)6480464CTDEstradiol results in increased expression of MAFF mRNAPMID:25210133
Maffmultiple interactionsISOMAFF (Homo sapiens)6480464CTD[Estradiol co-treated with EGF protein] results in increased expression of MAFF mRNA; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of MAFF mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of MAFF mRNA; Estradiol inhibits the reaction [Fulvestrant results in increased expression of MAFF mRNA]PMID:19619570 PMID:24758408 PMID:30165855 PMID:31646340
Maffmultiple interactionsISOMaff (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Estradiol] results in decreased expression of MAFF mRNAPMID:18691609
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