Gpd1 (glycerol-3-phosphate dehydrogenase 1)

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Gene: Gpd1 (glycerol-3-phosphate dehydrogenase 1) Rattus norvegicus

Analyze

Symbol:

Gpd1

Name:

glycerol-3-phosphate dehydrogenase 1

RGD ID:

621381

Description:

Enables NAD binding activity; glycerol-3-phosphate dehydrogenase (quinone) activity; and glycerol-3-phosphate dehydrogenase [NAD(P)+] activity. Involved in several processes, including NADH metabolic process; NADH oxidation; and glycerol-3-phosphate metabolic process. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Predicted to be active in cytosol. Orthologous to human GPD1 (glycerol-3-phosphate dehydrogenase 1); PARTICIPATES IN D-glycericacidemia pathway; electron transport chain pathway; familial lipoprotein lipase deficiency pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

glycerol 3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 1 (soluble); glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; GPD-C; Gpd3; GPDH; GPDH-C; MGC93453

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPD1 (glycerol-3-phosphate dehydrogenase 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Gpd1 (glycerol-3-phosphate dehydrogenase 1 (soluble))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpd1 (glycerol-3-phosphate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPD1 (glycerol-3-phosphate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPD1 (glycerol-3-phosphate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpd1 (glycerol-3-phosphate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPD1 (glycerol-3-phosphate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPD1 (glycerol-3-phosphate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpd1 (glycerol-3-phosphate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GPD1L (glycerol-3-phosphate dehydrogenase 1 like)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	GPD1 (glycerol-3-phosphate dehydrogenase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gpd1 (glycerol-3-phosphate dehydrogenase 1 (soluble))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpd1b (glycerol-3-phosphate dehydrogenase 1b)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpd1a (glycerol-3-phosphate dehydrogenase 1a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GPD1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Gpdh1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Gpdh2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Gpdh3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gpdh-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gpdh-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GPD2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gpd1	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	130,842,526 - 130,851,530 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	130,844,138 - 130,851,529 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	132,647,629 - 132,655,240 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	134,873,210 - 134,880,821 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	134,785,735 - 134,793,346 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	141,368,928 - 141,377,931 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	141,370,491 - 141,377,928 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	115,874,138 - 115,882,579 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	138,458,875 - 138,466,266 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	138,535,311 - 138,542,700 (+)	NCBI
Celera	7	127,325,535 - 127,332,926 (+)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

genetic disease (ISO)

Hypertriglyceridemia, Transient Infantile (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (ISO)

3-aminobenzoic acid (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (EXP,ISO)

aldehydo-D-glucose (EXP)

all-trans-retinoic acid (ISO)

aluminium atom (ISO)

aluminium(0) (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsenous acid (ISO)

benzamide (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

benzoates (ISO)

bexarotene (EXP)

bezafibrate (ISO)

bicalutamide (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

bromobenzene (EXP)

bucladesine (ISO)

buspirone (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

celastrol (ISO)

chlordecone (ISO)

cisplatin (ISO)

clobetasol (ISO)

clofibrate (EXP,ISO)

cobalt dichloride (EXP)

Cuprizon (EXP)

cyclosporin A (ISO)

cyproconazole (ISO)

D-glucose (EXP)

dehydroepiandrosterone (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dichloroacetic acid (ISO)

diclofenac (EXP)

diethylstilbestrol (EXP)

diquat (ISO)

diuron (EXP)

epoxiconazole (EXP,ISO)

ethanol (ISO)

fluoxetine (EXP)

flutamide (EXP)

fructose (EXP)

furan (EXP)

genistein (ISO)

glucose (EXP)

glycidol (EXP)

hydrazines (ISO)

hydrogen cyanide (ISO)

Indeno[1,2,3-cd]pyrene (ISO)

indometacin (ISO)

ketoconazole (EXP,ISO)

L-ascorbic acid (EXP)

lead diacetate (EXP)

leflunomide (ISO)

levofloxacin (EXP)

lithium atom (EXP)

lithium hydride (EXP)

methapyrilene (ISO)

Methylazoxymethanol acetate (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N-nitrosomorpholine (EXP)

nefazodone (EXP)

nickel atom (ISO)

nicotinic acid (ISO)

nitrofen (EXP)

Nonylphenol (EXP)

O-methyleugenol (ISO)

obeticholic acid (ISO)

oxaliplatin (EXP)

paracetamol (ISO)

paraquat (EXP)

perfluorododecanoic acid (EXP)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (EXP,ISO)

perfluorooctanoic acid (EXP)

permethrin (EXP)

phorbol 13-acetate 12-myristate (ISO)

picrotoxin (EXP)

pirinixic acid (EXP,ISO)

potassium cyanide (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

progesterone (ISO)

propiconazole (ISO)

resveratrol (EXP,ISO)

ritonavir (ISO)

rotenone (EXP)

sodium arsenite (EXP,ISO)

streptozocin (EXP)

sunitinib (ISO)

tebuconazole (ISO)

Tesaglitazar (EXP)

testosterone (ISO)

tetracycline (ISO)

tetraphene (ISO)

thapsigargin (EXP)

topotecan (EXP)

triptonide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

triticonazole (EXP)

troglitazone (EXP)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate metabolic process (IEA)

cellular response to cAMP (ISO)

cellular response to tumor necrosis factor (ISO)

gluconeogenesis (ISO)

glycerol-3-phosphate catabolic process (IEA)

glycerol-3-phosphate metabolic process (IBA,IDA,ISO)

glycerolipid metabolic process (IDA)

glycerophosphate shuttle (ISO)

NADH metabolic process (IDA)

NADH oxidation (IBA,IDA,ISO)

positive regulation of glycolytic process (ISO)

Cellular Component

cytosol (IBA,ISO)

glycerol-3-phosphate dehydrogenase complex (IEA)

Molecular Function

glycerol-3-phosphate dehydrogenase (quinone) activity (IDA)

glycerol-3-phosphate dehydrogenase [NAD(P)+] activity (IDA,IEA,ISO,TAS)

NAD binding (IDA,IEA)

protein binding (ISO)

protein homodimerization activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

D-glycericacidemia pathway (ISO)

electron transport chain pathway (ISO)

familial lipoprotein lipase deficiency pathway (ISO)

glycerol kinase deficiency pathway (ISO)

glycerolipid metabolic pathway (ISO)

glycerophospholipid metabolic pathway (IEA,ISO)

nicotinamide adenine dinucleotide metabolic pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Key enzymes of carbohydrate metabolism as targets of the 11.5-kDa Zn(2+)-binding protein (parathymosin).	Brand IA and Heinickel A, J Biol Chem. 1991 Nov 5;266(31):20984-9.
2.	Dramatic enhancement of the specific expression of the heart-type fatty acid binding protein in rat brown adipose tissue by cold exposure.	Daikoku T, etal., FEBS Lett 1997 Jun 30;410(2-3):383-6.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Neuronal and astrocytic shuttle mechanisms for cytosolic-mitochondrial transfer of reducing equivalents: current evidence and pharmacological tools.	McKenna MC, etal., Biochem Pharmacol. 2006 Feb 14;71(4):399-407. Epub 2005 Dec 20.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
11.	Normal myelin composition and phospholipid synthesis in adrenalectomized rats with reduced brain myelin and glycerol 3-phosphate dehydrogenase activity.	Preston SL and McMorris FA, J Neurochem. 1985 Dec;45(6):1771-8.
12.	GOA pipeline	RGD automated data pipeline
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Arachidonic acid metabolites of the lipoxygenase as well as the cyclooxygenase pathway may be involved in regulating preadipocyte differentiation.	Shillabeer G, etal., Metabolism. 1998 Apr;47(4):461-6.
16.	Role of NADH shuttles in glucose-induced insulin secretion from fetal beta-cells.	Tan C, etal., Diabetes. 2002 Oct;51(10):2989-96.
17.	Testis-specific expression of rat mitochondrial glycerol-3-phosphate dehydrogenase in haploid male germ cells.	Weitzel JM, etal., Biol Reprod 2003 Feb;68(2):699-707.
18.	NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences.	Ying W Antioxid Redox Signal. 2008 Feb;10(2):179-206.

Additional References at PubMed

PMID:3027100	PMID:6105153	PMID:11147825	PMID:12093800	PMID:12432448	PMID:12477932	PMID:12759350	PMID:15156407	PMID:15489334	PMID:18614015	PMID:18952046	PMID:19056867
PMID:20886417	PMID:22871113	PMID:23124204	PMID:23376485	PMID:26316108

Genomics

Comparative Map Data

Gpd1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	130,842,526 - 130,851,530 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	130,844,138 - 130,851,529 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	132,647,629 - 132,655,240 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	134,873,210 - 134,880,821 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	134,785,735 - 134,793,346 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	141,368,928 - 141,377,931 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	141,370,491 - 141,377,928 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	115,874,138 - 115,882,579 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	138,458,875 - 138,466,266 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	138,535,311 - 138,542,700 (+)	NCBI
Celera	7	127,325,535 - 127,332,926 (+)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

GPD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	50,104,008 - 50,111,313 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	50,103,982 - 50,111,313 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	50,497,791 - 50,505,096 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	48,784,068 - 48,791,363 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	48,784,067 - 48,791,360	NCBI
Celera	12	49,293,286 - 49,300,582 (+)	NCBI		Celera
Cytogenetic Map	12	q13.12	NCBI
HuRef	12	47,530,923 - 47,538,425 (+)	NCBI		HuRef
CHM1_1	12	50,463,752 - 50,471,253 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	50,067,090 - 50,074,395 (+)	NCBI		T2T-CHM13v2.0

Gpd1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	99,615,468 - 99,622,895 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	99,615,396 - 99,622,886 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	99,717,587 - 99,725,014 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	99,717,515 - 99,725,005 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	99,548,024 - 99,555,439 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	99,545,627 - 99,553,042 (+)	NCBI		MGSCv36	mm8
Celera	15	101,873,405 - 101,880,780 (+)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	56.13	NCBI

Gpd1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955547	676,342 - 690,777 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955547	676,661 - 683,906 (+)	NCBI	ChiLan1.0	ChiLan1.0

GPD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	12	44,065,672 - 44,082,276 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	38,644,466 - 38,651,924 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	39,541,544 - 39,549,040 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	39,541,550 - 39,549,040 (-)	Ensembl	panpan1.1		panPan2

GPD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	4,614,878 - 4,622,013 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	4,614,864 - 4,621,922 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	41,636,151 - 41,643,304 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	4,663,998 - 4,671,137 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	4,664,000 - 4,671,090 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	4,628,876 - 4,636,009 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	4,619,676 - 4,625,555 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	42,031,192 - 42,038,340 (+)	NCBI		UU_Cfam_GSD_1.0

Gpd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	65,394,517 - 65,402,211 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	7,762,643 - 7,770,309 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936512	7,762,325 - 7,770,007 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	16,007,448 - 16,017,825 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	16,008,179 - 16,021,676 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	16,330,841 - 16,334,498 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	46,329,479 - 46,339,227 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	46,331,569 - 46,337,439 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	199,781,124 - 199,788,621 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpd1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624816	2,203,731 - 2,210,509 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624816	2,203,731 - 2,211,006 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gpd1
35 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	697
Count of miRNA genes:	287
Interacting mature miRNAs:	369
Transcripts:	ENSRNOT00000026199
Prediction methods:	Microtar, Miranda, Pita, Pita,Targetscan, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
1558655	Swd4	Spike wave discharge measurement QTL 4	3.68	0.0002	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge severity grade (CMO:0001988)	7	86983365	131983365	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	90482196	135012528	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	91281130	135012528	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	96670164	135012528	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	102297359	133492884	Rat
731174	Uae23	Urinary albumin excretion QTL 23	2.4	0.0042	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	7	104603555	135012528	Rat
2306821	Bp335	Blood pressure QTL 335		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	106571501	135012528	Rat
631663	Bw6	Body weight QTL 6	3.4		body mass (VT:0001259)	body weight (CMO:0000012)	7	111075573	134976056	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	111182207	135012528	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	112308254	133492884	Rat
1357339	Stl14	Serum triglyceride level QTL 14	3.45	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	112729683	133492707	Rat
1354582	Stl11	Serum triglyceride level QTL 11	3.42		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	119513385	135012528	Rat

Markers in Region

RH127433

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	130,851,238 - 130,851,449 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	141,377,640 - 141,377,850	NCBI	Rnor6.0
Rnor_5.0	X	115,882,288 - 115,882,498	UniSTS	Rnor5.0
RGSC_v3.4	7	138,465,975 - 138,466,185	UniSTS	RGSC3.4
Celera	7	127,332,635 - 127,332,845	UniSTS
RH 3.4 Map	7	1078.1	UniSTS
Cytogenetic Map	7	q36	UniSTS

22.MMHAP28FLH1.seq

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	130,851,090 - 130,851,283 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	141,377,492 - 141,377,684	NCBI	Rnor6.0
Rnor_5.0	X	115,882,140 - 115,882,332	UniSTS	Rnor5.0
RGSC_v3.4	7	138,465,827 - 138,466,019	UniSTS	RGSC3.4
Celera	7	127,332,487 - 127,332,679	UniSTS
Cytogenetic Map	7	q36	UniSTS

BF399697

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	130,847,422 - 130,847,666 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	141,373,825 - 141,374,068	NCBI	Rnor6.0
Rnor_5.0	X	115,878,473 - 115,878,716	UniSTS	Rnor5.0
RGSC_v3.4	7	138,462,160 - 138,462,403	UniSTS	RGSC3.4
Celera	7	127,328,820 - 127,329,063	UniSTS
RH 3.4 Map	7	1051.11	UniSTS
Cytogenetic Map	7	q36	UniSTS

Gpd1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	130,850,541 - 130,851,498 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	141,376,943 - 141,377,899	NCBI	Rnor6.0
Rnor_5.0	X	115,881,591 - 115,882,547	UniSTS	Rnor5.0
RGSC_v3.4	7	138,465,278 - 138,466,234	UniSTS	RGSC3.4
Celera	7	127,331,938 - 127,332,894	UniSTS
Cytogenetic Map	7	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High			1		1			1
Medium	2	23	56	41	13	41	8	10	25	31	23	11	8
Low	1	20			5				49	4	18
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006257376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB002558	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC117865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000087662 ⟹ ENSRNOP00000074647

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	130,844,138 - 130,851,525 (+)	Ensembl
Rnor_6.0 Ensembl	7	141,370,491 - 141,377,928 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000097280 ⟹ ENSRNOP00000088513

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	130,844,138 - 130,851,529 (+)	Ensembl

RefSeq Acc Id:

NM_022215 ⟹ NP_071551

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	130,844,138 - 130,851,530 (+)	NCBI
Rnor_6.0	7	141,370,540 - 141,377,931 (+)	NCBI
Rnor_5.0	X	115,874,138 - 115,882,579 (+)	NCBI
RGSC_v3.4	7	138,458,875 - 138,466,266 (+)	RGD
Celera	7	127,325,535 - 127,332,926 (+)	RGD

Sequence:

show sequence

AGAAGCAGCACCATGGCTGGCAAGAAAGTCTGCATCGTAGGCTCCGGCAACTGGGGCTCAGCCA
TTGCCAAGATCGTGGGTAGTAATGCCAGCCAACTGGCACACTTTGATCCACGGGTGACCATGTG
GGTGTTTGAGGAAGACATCGGGGGCAGAAAGTTAACTGAGATCATCAACACGCAACACGAGAAT
GTGAAATACCTGCCGGGGCACAAGCTGCCCCCTAATGTGGTGGCTGTCCCAGATGTCGTCCAGG
CTGCAACAGGTGCTGACATCCTGGTTTTTGTGGTACCCCATCAGTTCATTGGCAAGATCTGTGA
CCAGCTCAAGGGCCACTTGAAAGCCAATACTATTGGCATATCTCTTATTAAGGGGATAGACGAG
GGCCCCAATGGACTGAAACTCATCTCTGAAGTGATTGGGGAGAGCCTTGGCATCCCTATGAGCG
TGCTGATGGGGGCCAACATTGCCAGTGAGGTGGCTGAAGAGAAGTTCTGTGAGACGACCATTGG
CTGCAAGGACCCTGCTCAGGGACAGCTCCTGAAGGAGCTGATGCAAACACCCAACTTCCGCATC
ACCGTGGTACAAGAGGTGGACACAGTGGAGATCTGTGGGGCCTTGAAGAATATAGTGGCTGTTG
GGGCTGGCTTCTGTGACGGGCTTGGCTTCGGTGACAACACCAAGGCGGCAGTGATCCGGCTGGG
GCTCATGGAGATGATCGCCTTCGCCAAGCTCTTCTGCAGTGGCTCTGTGTCCTCCGCCACCTTC
CTGGAGAGCTGTGGGGTCGCTGACCTCATCACGACCTGCTACGGGGGGCGGAACCGCAAGGTGG
CAGAGGCCTTCGCTCGCACCGGAAAGTCCATTGAGCAGCTGGAGAAAGAGATGCTGAACGGGCA
GAAGCTACAGGGGCCCCAGACAGCCCGGGAGCTGCACAGCATCCTCCAACACAAGGGCCTCGTG
GACAAGTTTCCCTTGTTCACCGCGGTGTACAAAGTGTGCTATGAGGGCCAGCCAGTGGGTGAGT
TCATCTGCTGCCTGCAGAACCACCCAGAGCACATGTGAATTCGGCCAGAGCCCAAGACAGACAG
CGCCTTTGCCCCAAGGGAGACAAGCAGAAGCGTGTGACACCACCAGTCTCCAGGACTTCCCATC
CAGCAGAGTCCTCTCTGAAGGACCCTGGGGACAGGAGGCTGTGGGGCTCGGCCACATACCTGGA
GATTGCTGTGGAACCTGCGGCCTCTCGCAGAACCACACCACGCTTCCTCCACGTCCTCTGGGAG
GTGTGGAACCAAGCCCCAATGCTGCCTGCTCTAGGGGTGCAGTTGGGGGAAGGGAAGGCGCCAA
GTCAAGGGTTGCTGGTTACTGCCTCACACACACTGGGAATCTGTCCCGTTAAGTGACTGAAGAA
GTTCTTTAGCCACAGGAAAGATGAGGCAAGGGCTGCCAAGGGAAGGGTCTGGACGCCTGAGCTG
ATGCAGACCCCAGAGACCCTTTTGGCCGACCTCTGCTAGGCCCCACGCAGCATCAATGATCTCA
CTGTTTGCTAACAAAATACAAAGCTCTCAAACAACTCCCTTCTAACTTCTCCTAGCAACATTTG
CCACCTCAGAAGCCTCTGCTTCCCCTTCCTCCAGGCTACTCTGGCACAAGAGAGCTCCACACTG
GCATTTCTGGCCCCGGGGCCTCCATTCTTCCCAGAGACTTCCTGGTCCCTAGAGCTTTGCCAGG
ACCTCCCCACCCTGTGTGACCTTTCCGAGCTCTCCCTTGCTGCACCCAGCTGCCAGCACCCTCT
TTGGGGAGCAGGAACTCAATCTGCTGACAGAGCTACACTTCTTCATAGCAGGCTCAGATGGCTC
AGGCTCCCCTGACCTTCTGATTTGTCCACCTCCCTAGTCAGGAGCTCTGGCTATGAGAAGCGCC
AGCCAGCCCCTCCAACTGCTGACGCCTTTAAAAAAGGCATCCGAACCCCATATCTTTCTTCTCA
GGGTTGTCCCCATCACTGACTTCATGTCTAACAGAATGTAGGATTCATAGCTTATCTTCCACAG
CTCCTTCAACCCGTATTCTTGACTCTACCCTTTCCTCTTGCCCAAGCCAGTGTGTCTTTCCGCT
GTTTTCAAACAGCCAGAGCGCTACCAAGTATCTGTATAGGCTTGGAGCCAAGGAGCAGCTCAAG
GTTCAGCAGGTTTCCACAATGGTTGGTGGGCCTTGAAAGGCCAAAGCCAGCTGCCCTTGGGACA
AGGTCCTCATGAGACCATAAGCACAGCACACATCAGGAGCTGGGGAACTCGAGGGAAGAAACAA
TTGAAAAGAGCCTGCCCTGGGGTGAGGGAAAGCAGCAGGGGGATGGGAGTATGCCTTGTACTGG
CCCCTTTCCAAGGTTTGGTGGCAGCAGGAGAATGTCACAGATCAGCAGCCTGGAGCCCTAGCTA
TAAATAGTCTCCGGGAGCTGAGAGGTTTCTCCCTCCACCAGGGGTCTCCATTTCGCGTGTGGCA
GCAACTGGCACACGGTGTCTCTGGCCAGCTTGCTATTAAACTAACACATCGGAGTGCCAGGCCC
CTCTCCGCTCCTAGCCTTTAAGAATTCAGTCTTATCAATGAAGGTCAGAGCCATTGGGAAAGGT
GAAGTGGGGGAGCCCTGTCATCGATCCCAACTGGGTCGGAACCCTCCCACGCATGACTCAATTC
AGAGCTGTTTCCCAGGAGGCTGGGGCGGGATGCAGACAGATTCCAACACCTTAACCTATGTTTG
CTCAGTCAACTGTGAATCTGAGGCCTTCTGTCAGGCCACTTGTCTACCCAATAAAGTGTGTTTT
TTCCAGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006257376 ⟹ XP_006257438

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	130,842,526 - 130,851,530 (+)	NCBI
Rnor_6.0	7	141,368,928 - 141,377,931 (+)	NCBI
Rnor_5.0	X	115,874,138 - 115,882,579 (+)	NCBI

Sequence:

show sequence

GTAGGACAGGCAGAGCCTTGAGAGAAGAATTGAAGGAAGATCAAGCTTACCCAGGACTGTGTAT
GCTGGTCACCGCCTTCTGCCCTTTCTGAAGCCTGGAAGGACTCTGGGCCATGTGGCATCAGTGG
TTCTACCTTTGCCCTTCCTTCCTGCCTTCCCTTTAGAGACCTTCAAATGGGGATTATCTGAGGT
GAAGGGGCTCACTGTGAGTCCCTGGCCTGTGAGTAACCACGATGACTGTAGTGGCTGTTCCTGG
TTGTCAACTTGACTATATCTGGAATGAACTACAATCCAGAACTGGAAGGCTCACCTGTGATCCT
GATCTTGAGGCTGGGAGATACAAGTTTCTGATCTGGATCTTGGCATGGAGATCTTGAGGCAAAG
TGGCTATGAATCCCAGGAGACTAAAAAGCAAGGAGCTCTCTGAGTTCAAGGTCATCTGGGACAA
AGCAAGTCCCAGATCCAGGCGTGGGGGTACACATCTTTAATCTGGGCCACACCTTCTGCTGGAG
GCCTATATAAGGACATTGGAAGGAGGAAGACTCACTCTTCGCCTGCCTGCCATGTGGGACTGAG
CCACTGCTAGATCCTTGGACTTCCATTCACAGCTGCTGCTGACCGTTGTTGGGGAGTTGGACTA
CAGACTGCCAGACTCCCTGTCCCTGGGTGCCAGCCTCTGGGCCACTTCAGGGGCGGAGCTTGGC
TGCACCCACGTGTGGTGGAGTTAAATACTCAGAGCCCACACCCGCCGGGGCAGAGAAGCAAGAA
GCAGCACCATGGCTGGCAAGAAAGTCTGCATCGTAGGCTCCGGCAACTGGGGCTCAGCCATTGC
CAAGATCGTGGGTAGTAATGCCAGCCAACTGGCACACTTTGATCCACGGGTGACCATGTGGGTG
TTTGAGGAAGACATCGGGGGCAGAAAGTTAACTGAGATCATCAACACGCAACACGAGAATGTGA
AATACCTGCCGGGGCACAAGCTGCCCCCTAATGTGGTGGCTGTCCCAGATGTCGTCCAGGCTGC
AACAGGTGCTGACATCCTGGTTTTTGTGGTACCCCATCAGTTCATTGGCAAGATCTGTGACCAG
CTCAAGGGCCACTTGAAAGCCAATACTATTGGCATATCTCTTATTAAGGGGATAGACGAGGGCC
CCAATGGACTGAAACTCATCTCTGAAGTGATTGGGGAGAGCCTTGGCATCCCTATGAGCGTGCT
GATGGGGGCCAACATTGCCAGTGAGGTGGCTGAAGAGAAGTTCTGTGAGACGACCATTGGCTGC
AAGGACCCTGCTCAGGGACAGCTCCTGAAGGAGCTGATGCAAACACCCAACTTCCGCATCACCG
TGGTACAAGAGGTGGACACAGTGGAGATCTGTGGGGCCTTGAAGAATATAGTGGCTGTTGGGGC
TGGCTTCTGTGACGGGCTTGGCTTCGGTGACAACACCAAGGCGGCAGTGATCCGGCTGGGGCTC
ATGGAGATGATCGCCTTCGCCAAGCTCTTCTGCAGTGGCTCTGTGTCCTCCGCCACCTTCCTGG
AGAGCTGTGGGGTCGCTGACCTCATCACGACCTGCTACGGGGGGCGGAACCGCAAGGTGGCAGA
GGCCTTCGCTCGCACCGGAAAGTCCATTGAGCAGCTGGAGAAAGAGATGCTGAACGGGCAGAAG
CTACAGGGGCCCCAGACAGCCCGGGAGCTGCACAGCATCCTCCAACACAAGGGCCTCGTGGACA
AGTTTCCCTTGTTCACCGCGGTGTACAAAGTGTGCTATGAGGGCCAGCCAGTGGGTGAGTTCAT
CTGCTGCCTGCAGAACCACCCAGAGCACATGTGAATTCGGCCAGAGCCCAAGACAGACAGCGCC
TTTGCCCCAAGGGAGACAAGCAGAAGCGTGTGACACCACCAGTCTCCAGGACTTCCCATCCAGC
AGAGTCCTCTCTGAAGGACCCTGGGGACAGGAGGCTGTGGGGCTCGGCCACATACCTGGAGATT
GCTGTGGAACCTGCGGCCTCTCGCAGAACCACACCACGCTTCCTCCACGTCCTCTGGGAGGTGT
GGAACCAAGCCCCAATGCTGCCTGCTCTAGGGGTGCAGTTGGGGGAAGGGAAGGCGCCAAGTCA
AGGGTTGCTGGTTACTGCCTCACACACACTGGGAATCTGTCCCGTTAAGTGACTGAAGAAGTTC
TTTAGCCACAGGAAAGATGAGGCAAGGGCTGCCAAGGGAAGGGTCTGGACGCCTGAGCTGATGC
AGACCCCAGAGACCCTTTTGGCCGACCTCTGCTAGGCCCCACGCAGCATCAATGATCTCACTGT
TTGCTAACAAAATACAAAGCTCTCAAACAACTCCCTTCTAACTTCTCCTAGCAACATTTGCCAC
CTCAGAAGCCTCTGCTTCCCCTTCCTCCAGGCTACTCTGGCACAAGAGAGCTCCACACTGGCAT
TTCTGGCCCCGGGGCCTCCATTCTTCCCAGAGACTTCCTGGTCCCTAGAGCTTTGCCAGGACCT
CCCCACCCTGTGTGACCTTTCCGAGCTCTCCCTTGCTGCACCCAGCTGCCAGCACCCTCTTTGG
GGAGCAGGAACTCAATCTGCTGACAGAGCTACACTTCTTCATAGCAGGCTCAGATGGCTCAGGC
TCCCCTGACCTTCTGATTTGTCCACCTCCCTAGTCAGGAGCTCTGGCTATGAGAAGCGCCAGCC
AGCCCCTCCAACTGCTGACGCCTTTAAAAAAGGCATCCGAACCCCATATCTTTCTTCTCAGGGT
TGTCCCCATCACTGACTTCATGTCTAACAGAATGTAGGATTCATAGCTTATCTTCCACAGCTCC
TTCAACCCGTATTCTTGACTCTACCCTTTCCTCTTGCCCAAGCCAGTGTGTCTTTCCGCTGTTT
TCAAACAGCCAGAGCGCTACCAAGTATCTGTATAGGCTTGGAGCCAAGGAGCAGCTCAAGGTTC
AGCAGGTTTCCACAATGGTTGGTGGGCCTTGAAAGGCCAAAGCCAGCTGCCCTTGGGACAAGGT
CCTCATGAGACCATAAGCACAGCACACATCAGGAGCTGGGGAACTCGAGGGAAGAAACAATTGA
AAAGAGCCTGCCCTGGGGTGAGGGAAAGCAGCAGGGGGATGGGAGTATGCCTTGTACTGGCCCC
TTTCCAAGGTTTGGTGGCAGCAGGAGAATGTCACAGATCAGCAGCCTGGAGCCCTAGCTATAAA
TAGTCTCCGGGAGCTGAGAGGTTTCTCCCTCCACCAGGGGTCTCCATTTCGCGTGTGGCAGCAA
CTGGCACACGGTGTCTCTGGCCAGCTTGCTATTAAACTAACACATCGGAGTGCCAGGCCCCTCT
CCGCTCCTAGCCTTTAAGAATTCAGTCTTATCAATGAAGGTCAGAGCCATTGGGAAAGGTGAAG
TGGGGGAGCCCTGTCATCGATCCCAACTGGGTCGGAACCCTCCCACGCATGACTCAATTCAGAG
CTGTTTCCCAGGAGGCTGGGGCGGGATGCAGACAGATTCCAACACCTTAACCTATGTTTGCTCA
GTCAACTGTGAATCTGAGGCCTTCTGTCAGGCCACTTGTCTACCCAATAAAGTGTGTTTTTTCC
AGAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_071551	(Get FASTA)	NCBI Sequence Viewer
	XP_006257438	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88396	(Get FASTA)	NCBI Sequence Viewer
	BAA21763	(Get FASTA)	NCBI Sequence Viewer
	EDL86970	(Get FASTA)	NCBI Sequence Viewer
	EDL86971	(Get FASTA)	NCBI Sequence Viewer
	O35077	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_071551 ⟸ NM_022215

- UniProtKB:

Q5I0F4 (UniProtKB/Swiss-Prot), O35077 (UniProtKB/Swiss-Prot), A6KCH1 (UniProtKB/TrEMBL), A0A8I6AA38 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGKKVCIVGSGNWGSAIAKIVGSNASQLAHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYL
PGHKLPPNVVAVPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGIDEGPNG
LKLISEVIGESLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQGQLLKELMQTPNFRITVVQ
EVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGSVSSATFLESC
GVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFP
LFTAVYKVCYEGQPVGEFICCLQNHPEHM

hide sequence

RefSeq Acc Id:	XP_006257438 ⟸ XM_006257376
- Peptide Label:	isoform X1
- UniProtKB:	Q5I0F4 (UniProtKB/Swiss-Prot), O35077 (UniProtKB/Swiss-Prot), A6KCH1 (UniProtKB/TrEMBL), A0A8I6AA38 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGKKVCIVGSGNWGSAIAKIVGSNASQLAHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYL PGHKLPPNVVAVPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGIDEGPNG LKLISEVIGESLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQGQLLKELMQTPNFRITVVQ EVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGSVSSATFLESC GVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFP LFTAVYKVCYEGQPVGEFICCLQNHPEHM hide sequence

RefSeq Acc Id:

ENSRNOP00000074647 ⟸ ENSRNOT00000087662

RefSeq Acc Id:

ENSRNOP00000088513 ⟸ ENSRNOT00000097280

Protein Domains

Glycerol-3-phosphate dehydrogenase NAD-dependent C- Glycerol-3-phosphate dehydrogenase NAD-dependent N-

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O35077-F1-model_v2	AlphaFold	O35077	1-349	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621381	AgrOrtholog
BioCyc Gene	G2FUF-32059	BioCyc
BioCyc Pathway	PWY-6118 [glycerol-3-phosphate shuttle]	BioCyc
	PWY-7411 [phosphatidate biosynthesis (yeast)]	BioCyc
Ensembl Genes	ENSRNOG00000056457	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000074647	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000088513.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000087662	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000097280.1	UniProtKB/TrEMBL
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7108237	IMAGE-MGC_LOAD
InterPro	6-PGluconate_DH-like_C_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	6PGD_dom2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G3P_DH_NAD-dep	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G3P_DH_NAD-dep_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G3P_DH_NAD-dep_euk	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G3P_DH_NAD-dep_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:60666	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93453	IMAGE-MGC_LOAD
NCBI Gene	60666	ENTREZGENE
PANTHER	GLYCEROL-3-PHOSPHATE DEHYDROGENASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)], CYTOPLASMIC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	NAD_Gly3P_dh_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NAD_Gly3P_dh_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gpd1	PhenoGen
PIRSF	Glycerol-3-P_dh	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	GPDHDRGNASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	NAD_G3PDH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48179	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF51735	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6AA38	ENTREZGENE, UniProtKB/TrEMBL
	A6KCH1	ENTREZGENE, UniProtKB/TrEMBL
	A6KCH2_RAT	UniProtKB/TrEMBL
	GPDA_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q5I0F4	ENTREZGENE
UniProt Secondary	Q5I0F4	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-12	Gpd1	glycerol-3-phosphate dehydrogenase 1	Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	Gpd3	glycerol 3-phosphate dehydrogenase	Symbol and Name updated	1299863	APPROVED
2002-08-07	Gpd3	glycerol 3-phosphate dehydrogenase			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_transcript	contains a cAMP-response element (CRE) site at -57 that was active in the testis	704468

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)