Gpd1 (glycerol-3-phosphate dehydrogenase 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Gpd1 (glycerol-3-phosphate dehydrogenase 1) Rattus norvegicus
Analyze
Symbol: Gpd1
Name: glycerol-3-phosphate dehydrogenase 1
RGD ID: 621381
Description: Enables NAD binding activity and glycerol-3-phosphate dehydrogenase (quinone) activity. Involved in NADH oxidation; glycerol-3-phosphate metabolic process; and glycerolipid metabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human GPD1 (glycerol-3-phosphate dehydrogenase 1); PARTICIPATES IN D-glycericacidemia pathway; electron transport chain pathway; familial lipoprotein lipase deficiency pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: glycerol 3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 1 (soluble); glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; GPD-C; Gpd3; GPDH; GPDH-C; MGC93453
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,722,982 - 132,730,373 (+)NCBIGRCr8
mRatBN7.27130,842,526 - 130,851,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,844,138 - 130,851,529 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,647,629 - 132,655,240 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,873,210 - 134,880,821 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,785,735 - 134,793,346 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,368,928 - 141,377,931 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,370,491 - 141,377,928 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,874,138 - 115,882,579 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,458,875 - 138,466,266 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17138,535,311 - 138,542,700 (+)NCBI
Celera7127,325,535 - 127,332,926 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
3-aminobenzoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
aluminium atom  (ISO)
aluminium(0)  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzamide  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
benzoates  (ISO)
bexarotene  (EXP)
bezafibrate  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
bucladesine  (ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
chlordecone  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cyproconazole  (ISO)
D-glucose  (EXP)
dehydroepiandrosterone  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (EXP)
diethylstilbestrol  (EXP)
diquat  (ISO)
diuron  (EXP)
epoxiconazole  (EXP,ISO)
ethanol  (ISO)
fluoxetine  (EXP)
flutamide  (EXP)
fructose  (EXP)
furan  (EXP)
genistein  (ISO)
glucose  (EXP)
glycidol  (EXP)
hydrazines  (ISO)
hydrogen cyanide  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (ISO)
ketoconazole  (EXP,ISO)
L-ascorbic acid  (EXP)
lead diacetate  (EXP)
leflunomide  (ISO)
levofloxacin  (EXP)
lithium atom  (EXP)
lithium hydride  (EXP)
Mesaconitine  (EXP)
methapyrilene  (ISO)
Methylazoxymethanol acetate  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosomorpholine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nicotinic acid  (ISO)
nitrofen  (EXP)
Nonylphenol  (EXP)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
oxaliplatin  (EXP)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
perfluorododecanoic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
picrotoxin  (EXP)
pirinixic acid  (EXP,ISO)
potassium cyanide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
resveratrol  (EXP,ISO)
ritonavir  (ISO)
rotenone  (EXP)
sodium arsenite  (EXP,ISO)
streptozocin  (EXP)
sunitinib  (ISO)
tebuconazole  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetracycline  (ISO)
tetraphene  (ISO)
thapsigargin  (EXP)
topotecan  (EXP)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
triticonazole  (EXP)
troglitazone  (EXP)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Key enzymes of carbohydrate metabolism as targets of the 11.5-kDa Zn(2+)-binding protein (parathymosin). Brand IA and Heinickel A, J Biol Chem. 1991 Nov 5;266(31):20984-9.
2. Dramatic enhancement of the specific expression of the heart-type fatty acid binding protein in rat brown adipose tissue by cold exposure. Daikoku T, etal., FEBS Lett 1997 Jun 30;410(2-3):383-6.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Neuronal and astrocytic shuttle mechanisms for cytosolic-mitochondrial transfer of reducing equivalents: current evidence and pharmacological tools. McKenna MC, etal., Biochem Pharmacol. 2006 Feb 14;71(4):399-407. Epub 2005 Dec 20.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. Normal myelin composition and phospholipid synthesis in adrenalectomized rats with reduced brain myelin and glycerol 3-phosphate dehydrogenase activity. Preston SL and McMorris FA, J Neurochem. 1985 Dec;45(6):1771-8.
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Arachidonic acid metabolites of the lipoxygenase as well as the cyclooxygenase pathway may be involved in regulating preadipocyte differentiation. Shillabeer G, etal., Metabolism. 1998 Apr;47(4):461-6.
16. Role of NADH shuttles in glucose-induced insulin secretion from fetal beta-cells. Tan C, etal., Diabetes. 2002 Oct;51(10):2989-96.
17. Testis-specific expression of rat mitochondrial glycerol-3-phosphate dehydrogenase in haploid male germ cells. Weitzel JM, etal., Biol Reprod 2003 Feb;68(2):699-707.
18. NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences. Ying W Antioxid Redox Signal. 2008 Feb;10(2):179-206.
Additional References at PubMed
PMID:3027100   PMID:6105153   PMID:11147825   PMID:12093800   PMID:12432448   PMID:12477932   PMID:12759350   PMID:15156407   PMID:15489334   PMID:18614015   PMID:18952046   PMID:19056867  
PMID:20886417   PMID:22871113   PMID:23124204   PMID:23376485   PMID:26316108  


Genomics

Comparative Map Data
Gpd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,722,982 - 132,730,373 (+)NCBIGRCr8
mRatBN7.27130,842,526 - 130,851,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,844,138 - 130,851,529 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,647,629 - 132,655,240 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,873,210 - 134,880,821 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,785,735 - 134,793,346 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,368,928 - 141,377,931 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,370,491 - 141,377,928 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,874,138 - 115,882,579 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,458,875 - 138,466,266 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17138,535,311 - 138,542,700 (+)NCBI
Celera7127,325,535 - 127,332,926 (+)NCBICelera
Cytogenetic Map7q36NCBI
GPD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381250,104,008 - 50,111,313 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1250,103,982 - 50,111,313 (+)EnsemblGRCh38hg38GRCh38
GRCh371250,497,791 - 50,505,096 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,784,068 - 48,791,363 (+)NCBINCBI36Build 36hg18NCBI36
Build 341248,784,067 - 48,791,360NCBI
Celera1249,293,286 - 49,300,582 (+)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,530,923 - 47,538,425 (+)NCBIHuRef
CHM1_11250,463,752 - 50,471,253 (+)NCBICHM1_1
T2T-CHM13v2.01250,067,090 - 50,074,395 (+)NCBIT2T-CHM13v2.0
Gpd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,615,468 - 99,622,895 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,615,396 - 99,622,886 (+)EnsemblGRCm39 Ensembl
GRCm381599,717,587 - 99,725,014 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,717,515 - 99,725,005 (+)EnsemblGRCm38mm10GRCm38
MGSCv371599,548,024 - 99,555,439 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,545,627 - 99,553,042 (+)NCBIMGSCv36mm8
Celera15101,873,405 - 101,880,780 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Gpd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547676,342 - 690,777 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955547676,661 - 683,906 (+)NCBIChiLan1.0ChiLan1.0
GPD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,068,910 - 44,085,459 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,065,672 - 44,082,276 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,644,466 - 38,651,924 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,541,544 - 39,549,040 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,541,550 - 39,549,040 (-)Ensemblpanpan1.1panPan2
GPD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,614,878 - 4,622,013 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,614,864 - 4,621,922 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,636,151 - 41,643,304 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,663,998 - 4,671,137 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,664,000 - 4,671,090 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,628,876 - 4,636,009 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,619,676 - 4,625,555 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02742,031,192 - 42,038,340 (+)NCBIUU_Cfam_GSD_1.0
Gpd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,394,517 - 65,402,211 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,762,643 - 7,770,309 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,762,325 - 7,770,007 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl516,007,448 - 16,017,825 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1516,008,179 - 16,021,676 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,330,841 - 16,334,498 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,329,479 - 46,339,227 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1146,331,569 - 46,337,439 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037199,781,124 - 199,788,621 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,203,731 - 2,210,509 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,203,731 - 2,211,006 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gpd1
48 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:697
Count of miRNA genes:287
Interacting mature miRNAs:369
Transcripts:ENSRNOT00000026199
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
RH127433  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,851,238 - 130,851,449 (+)MAPPERmRatBN7.2
Rnor_6.07141,377,640 - 141,377,850NCBIRnor6.0
Rnor_5.0X115,882,288 - 115,882,498UniSTSRnor5.0
RGSC_v3.47138,465,975 - 138,466,185UniSTSRGSC3.4
Celera7127,332,635 - 127,332,845UniSTS
RH 3.4 Map71078.1UniSTS
Cytogenetic Map7q36UniSTS
22.MMHAP28FLH1.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,851,090 - 130,851,283 (+)MAPPERmRatBN7.2
Rnor_6.07141,377,492 - 141,377,684NCBIRnor6.0
Rnor_5.0X115,882,140 - 115,882,332UniSTSRnor5.0
RGSC_v3.47138,465,827 - 138,466,019UniSTSRGSC3.4
Celera7127,332,487 - 127,332,679UniSTS
Cytogenetic Map7q36UniSTS
BF399697  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,847,422 - 130,847,666 (+)MAPPERmRatBN7.2
Rnor_6.07141,373,825 - 141,374,068NCBIRnor6.0
Rnor_5.0X115,878,473 - 115,878,716UniSTSRnor5.0
RGSC_v3.47138,462,160 - 138,462,403UniSTSRGSC3.4
Celera7127,328,820 - 127,329,063UniSTS
RH 3.4 Map71051.11UniSTS
Cytogenetic Map7q36UniSTS
Gpd1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27130,850,541 - 130,851,498 (+)MAPPERmRatBN7.2
Rnor_6.07141,376,943 - 141,377,899NCBIRnor6.0
Rnor_5.0X115,881,591 - 115,882,547UniSTSRnor5.0
RGSC_v3.47138,465,278 - 138,466,234UniSTSRGSC3.4
Celera7127,331,938 - 127,332,894UniSTS
Cytogenetic Map7q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000087662   ⟹   ENSRNOP00000074647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,844,138 - 130,851,525 (+)Ensembl
Rnor_6.0 Ensembl7141,370,491 - 141,377,928 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097280   ⟹   ENSRNOP00000088513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7130,844,138 - 130,851,529 (+)Ensembl
RefSeq Acc Id: NM_022215   ⟹   NP_071551
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87132,722,982 - 132,730,373 (+)NCBI
mRatBN7.27130,844,138 - 130,851,530 (+)NCBI
Rnor_6.07141,370,540 - 141,377,931 (+)NCBI
Rnor_5.0X115,874,138 - 115,882,579 (+)NCBI
RGSC_v3.47138,458,875 - 138,466,266 (+)RGD
Celera7127,325,535 - 127,332,926 (+)RGD
Sequence:
RefSeq Acc Id: NP_071551   ⟸   NM_022215
- UniProtKB: Q5I0F4 (UniProtKB/Swiss-Prot),   O35077 (UniProtKB/Swiss-Prot),   A6KCH1 (UniProtKB/TrEMBL),   A0A8I6AA38 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074647   ⟸   ENSRNOT00000087662
Ensembl Acc Id: ENSRNOP00000088513   ⟸   ENSRNOT00000097280
Protein Domains
Glycerol-3-phosphate dehydrogenase NAD-dependent C-   Glycerol-3-phosphate dehydrogenase NAD-dependent N-

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35077-F1-model_v2 AlphaFold O35077 1-349 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695651
Promoter ID:EPDNEW_R6174
Type:multiple initiation site
Name:Gpd1_1
Description:glycerol-3-phosphate dehydrogenase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07141,370,531 - 141,370,591EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621381 AgrOrtholog
BioCyc Gene G2FUF-32059 BioCyc
BioCyc Pathway PWY-6118 [glycerol-3-phosphate shuttle] BioCyc
  PWY-7411 [phosphatidate biosynthesis (yeast)] BioCyc
BioCyc Pathway Image PWY-6118 BioCyc
  PWY-7411 BioCyc
Ensembl Genes ENSRNOG00000056457 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055028882 UniProtKB/Swiss-Prot
  ENSRNOG00060006691 UniProtKB/Swiss-Prot
  ENSRNOG00065023014 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000087662.2 UniProtKB/Swiss-Prot
  ENSRNOT00000097280.1 UniProtKB/TrEMBL
  ENSRNOT00055050035 UniProtKB/Swiss-Prot
  ENSRNOT00060010968 UniProtKB/Swiss-Prot
  ENSRNOT00065039331 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7108237 IMAGE-MGC_LOAD
InterPro 6-PGluconate_DH-like_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6PGD_dom2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G3P_DH_NAD-dep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G3P_DH_NAD-dep_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G3P_DH_NAD-dep_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G3P_DH_NAD-dep_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:60666 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93453 IMAGE-MGC_LOAD
NCBI Gene 60666 ENTREZGENE
PANTHER GLYCEROL-3-PHOSPHATE DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)], CYTOPLASMIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NAD_Gly3P_dh_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD_Gly3P_dh_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gpd1 PhenoGen
PIRSF Glycerol-3-P_dh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GPDHDRGNASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NAD_G3PDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000056457 RatGTEx
  ENSRNOG00055028882 RatGTEx
  ENSRNOG00060006691 RatGTEx
  ENSRNOG00065023014 RatGTEx
Superfamily-SCOP SSF48179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AA38 ENTREZGENE, UniProtKB/TrEMBL
  A6KCH1 ENTREZGENE, UniProtKB/TrEMBL
  A6KCH2_RAT UniProtKB/TrEMBL
  GPDA_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5I0F4 ENTREZGENE
UniProt Secondary Q5I0F4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-12 Gpd1  glycerol-3-phosphate dehydrogenase 1  Gpd1  glycerol-3-phosphate dehydrogenase 1 (soluble)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Gpd1  glycerol-3-phosphate dehydrogenase 1 (soluble)  Gpd3  glycerol 3-phosphate dehydrogenase  Symbol and Name updated 1299863 APPROVED
2002-08-07 Gpd3  glycerol 3-phosphate dehydrogenase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_transcript contains a cAMP-response element (CRE) site at -57 that was active in the testis 704468