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Gene: Wnt1 (Wnt family member 1) Rattus norvegicus
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Symbol: Wnt1
Name: Wnt family member 1
Description: Predicted to have protein domain specific binding activity; signaling receptor binding activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in animal organ regeneration; cellular response to peptide hormone stimulus; and hepatocyte differentiation. Predicted to localize to cell surface; cytoplasm; and extracellular space. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 15 and osteoporosis. Orthologous to human WNT1 (Wnt family member 1); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; basal cell carcinoma pathway; INTERACTS WITH atrazine; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Int1; proto-oncogene Wnt-1; wingless-related MMTV integration site 1; Wingless-type MMTV integration site 1 homolog; Wingless-type MMTV integration site 1, homolog; wingless-type MMTV integration site family, member 1; wingless-type MMTV integration site family, member 1 (mapped); Wnt1_mapped
Orthologs:
Homo sapiens (human) : WNT1 (Wnt family member 1)  HGNC  Alliance
Mus musculus (house mouse) : Wnt1 (wingless-type MMTV integration site family, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnt1 (Wnt family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : WNT1 (Wnt family member 1)
Canis lupus familiaris (dog) : WNT1 (Wnt family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnt1 (Wnt family member 1)
Sus scrofa (pig) : WNT1 (Wnt family member 1)
Chlorocebus sabaeus (African green monkey) : WNT1 (Wnt family member 1)
Heterocephalus glaber (naked mole-rat) : Wnt1 (Wnt family member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07140,464,999 - 140,469,046 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,464,999 - 140,469,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X114,975,118 - 114,979,165 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,557,836 - 137,561,883 (+)NCBIRGSC3.4rn4RGSC3.4
Celera7126,427,473 - 126,431,520 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Wnt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1597195
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.