Wnt1 (Wnt family member 1) - Rat Genome Database

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Gene: Wnt1 (Wnt family member 1) Chinchilla lanigera
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Symbol: Wnt1
Name: Wnt family member 1
RGD ID: 9038218
Description: ENCODES a protein that exhibits cytokine activity (ortholog); protein domain specific binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN animal organ regeneration (ortholog); astrocyte-dopaminergic neuron signaling (ortholog); bone development (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); genetic disease (ortholog); keratoconus (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: proto-oncogene Wnt-1; wingless-type MMTV integration site family, member 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555007,797,060 - 7,811,167 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555007,797,063 - 7,811,142 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ regeneration  (ISO)
astrocyte-dopaminergic neuron signaling  (ISO)
bone development  (ISO)
branching involved in ureteric bud morphogenesis  (ISO)
canonical Wnt signaling pathway  (ISO)
canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation  (ISO)
cell proliferation in midbrain  (ISO)
cell-cell signaling  (ISO)
cellular response to peptide hormone stimulus  (ISO)
central nervous system morphogenesis  (ISO)
cerebellum development  (ISO)
cerebellum formation  (ISO)
diencephalon development  (ISO)
dopaminergic neuron differentiation  (ISO)
embryonic axis specification  (ISO)
embryonic brain development  (ISO)
forebrain anterior/posterior pattern specification  (ISO)
hematopoietic stem cell proliferation  (ISO)
hepatocyte differentiation  (ISO)
inner ear morphogenesis  (ISO)
metencephalon development  (ISO)
midbrain development  (ISO)
midbrain dopaminergic neuron differentiation  (ISO)
midbrain-hindbrain boundary development  (ISO)
midbrain-hindbrain boundary maturation during brain development  (ISO)
myoblast fusion  (ISO)
myotube differentiation  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of BMP signaling pathway  (ISO)
negative regulation of cell aging  (ISO)
negative regulation of cell differentiation  (ISO)
negative regulation of cell-cell adhesion  (ISO)
negative regulation of cell-substrate adhesion  (ISO)
negative regulation of fat cell differentiation  (ISO)
negative regulation of oxidative stress-induced neuron death  (ISO)
negative regulation of transforming growth factor beta receptor signaling pathway  (ISO)
negative regulation of ubiquitin-dependent protein catabolic process  (ISO)
neurogenesis  (ISO)
neuron fate commitment  (ISO)
neuron fate determination  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of dermatome development  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of insulin-like growth factor receptor signaling pathway  (ISO)
positive regulation of lamellipodium assembly  (ISO)
positive regulation of Notch signaling pathway  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
response to wounding  (ISO)
signal transduction in response to DNA damage  (ISO)
Spemann organizer formation  (ISO)
spinal cord association neuron differentiation  (ISO)
T cell differentiation in thymus  (ISO)
ubiquitin-dependent SMAD protein catabolic process  (ISO)
Wnt signaling pathway  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Wnt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555007,797,060 - 7,811,167 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555007,797,063 - 7,811,142 (+)NCBIChiLan1.0ChiLan1.0
WNT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1248,978,322 - 48,982,620 (+)EnsemblGRCh38hg38GRCh38
GRCh381248,978,322 - 48,982,620 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371249,372,105 - 49,376,403 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,658,503 - 47,662,746 (+)NCBINCBI36hg18NCBI36
Build 341247,658,502 - 47,662,746NCBI
Celera1248,167,028 - 48,171,188 (+)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1246,403,758 - 46,407,918 (+)NCBIHuRef
CHM1_11249,338,028 - 49,342,188 (+)NCBICHM1_1
Wnt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,687,738 - 98,691,711 (+)NCBIGRCm39mm39
GRCm39 Ensembl1598,687,738 - 98,691,718 (+)Ensembl
GRCm381598,789,857 - 98,793,830 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,789,857 - 98,793,837 (+)EnsemblGRCm38mm10GRCm38
MGSCv371598,620,288 - 98,624,261 (+)NCBIGRCm37mm9NCBIm37
MGSCv361598,617,891 - 98,621,864 (+)NCBImm8
Celera15100,939,306 - 100,943,279 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1554.65NCBI
Wnt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27129,938,604 - 129,942,651 (+)NCBI
Rnor_6.0 Ensembl7140,464,999 - 140,469,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07140,464,999 - 140,469,046 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X114,975,118 - 114,979,165 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,557,836 - 137,561,883 (+)NCBIRGSC3.4rn4RGSC3.4
Celera7126,427,473 - 126,431,520 (+)NCBICelera
Cytogenetic Map7q36NCBI
WNT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11240,648,413 - 40,652,583 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,648,413 - 40,652,583 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01239,767,839 - 39,772,460 (-)NCBIMhudiblu_PPA_v0panPan3
WNT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,588,151 - 5,592,254 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,574,940 - 5,592,060 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,665,906 - 40,669,560 (+)NCBI
ROS_Cfam_1.0275,639,156 - 5,642,810 (-)NCBI
UMICH_Zoey_3.1275,603,082 - 5,606,734 (-)NCBI
UNSW_CanFamBas_1.0275,593,278 - 5,596,931 (-)NCBI
UU_Cfam_GSD_1.02741,058,211 - 41,061,867 (+)NCBI
Wnt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494566,379,465 - 66,383,960 (-)NCBI
SpeTri2.0NW_0049365126,781,001 - 6,785,358 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,010,985 - 15,014,079 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,010,607 - 15,015,007 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,420,829 - 15,425,219 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WNT1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,217,402 - 45,222,996 (+)NCBI
ChlSab1.1 Ensembl1145,219,027 - 45,222,017 (+)Ensembl
Vero_WHO_p1.0NW_023666037200,920,985 - 200,926,676 (-)NCBI
Wnt1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248163,209,605 - 3,212,969 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000004215   ⟹   ENSCLAP00000004134
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555007,797,060 - 7,811,167 (+)Ensembl
RefSeq Acc Id: XM_005406674   ⟹   XP_005406731
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555007,797,063 - 7,811,142 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005406731 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005406731   ⟸   XM_005406674
- Sequence:
RefSeq Acc Id: ENSCLAP00000004134   ⟸   ENSCLAT00000004215


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002943 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000004134 ENTREZGENE
Ensembl Transcript ENSCLAT00000004215 ENTREZGENE
NCBI Gene Wnt1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Wnt1  Wnt family member 1    wingless-type MMTV integration site family, member 1  Symbol and/or name change 5135510 APPROVED