Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Slc4a8 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Slc4a8 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SLC4A8 mRNA | CTD | PMID:36331819 | Slc4a8 | Rat | 1,2-dichloroethane | increases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of SLC4A8 mRNA | CTD | PMID:28960355 | Slc4a8 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of SLC4A8 mRNA | CTD | PMID:22206623 | Slc4a8 | Rat | 17beta-estradiol | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Estradiol results in increased expression of SLC4A8 mRNA | CTD | PMID:17962382 | Slc4a8 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19095052 | Slc4a8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Slc4a8 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SLC4A8 mRNA | CTD | PMID:21570461 | Slc4a8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SLC4A8 mRNA | CTD | PMID:32109520 and PMID:33387578 | Slc4a8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SLC4A8 mRNA | CTD | PMID:29673856 | Slc4a8 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Slc4a8 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Slc4a8 (Mus musculus) | 6480464 | bisphenol S affects the methylation of SLC4A8 gene | CTD | PMID:31683443 | Slc4a8 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | Fenretinide results in increased expression of SLC4A8 mRNA | CTD | PMID:28973697 | Slc4a8 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SLC4A8 mRNA | CTD | PMID:24780913 | Slc4a8 | Rat | actinomycin D | multiple interactions | ISO | SLC4A8 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of SLC4A8 mRNA | CTD | PMID:38460933 | Slc4a8 | Rat | all-trans-retinoic acid | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of SLC4A8 mRNA | CTD | PMID:23724009 | Slc4a8 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of SLC4A8 gene | CTD | PMID:28931070 and PMID:35440735 | Slc4a8 | Rat | benzo[a]pyrene | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SLC4A8 mRNA | CTD | PMID:17879257 more ... | Slc4a8 | Rat | benzo[a]pyrene | increases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SLC4A8 mRNA | CTD | PMID:32417428 | Slc4a8 | Rat | benzo[a]pyrene | increases methylation | ISO | SLC4A8 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SLC4A8 3' UTR more ... | CTD | PMID:27901495 | Slc4a8 | Rat | beta-lapachone | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of SLC4A8 mRNA | CTD | PMID:38218311 | Slc4a8 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLC4A8 mRNA | CTD | PMID:25181051 | Slc4a8 | Rat | bisphenol A | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SLC4A8 mRNA | CTD | PMID:31715268 | Slc4a8 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SLC4A8 mRNA | CTD | PMID:30816183 and PMID:32528016 | Slc4a8 | Rat | bisphenol A | increases methylation | ISO | Slc4a8 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of SLC4A8 promoter | CTD | PMID:27312807 | Slc4a8 | Rat | bisphenol A | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SLC4A8 mRNA | CTD | PMID:27685785 | Slc4a8 | Rat | butanal | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of SLC4A8 mRNA | CTD | PMID:26079696 | Slc4a8 | Rat | cadmium dichloride | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of SLC4A8 mRNA | CTD | PMID:21457566 | Slc4a8 | Rat | cisplatin | multiple interactions | ISO | SLC4A8 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of SLC4A8 mRNA | CTD | PMID:27392435 | Slc4a8 | Rat | cisplatin | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of SLC4A8 mRNA | CTD | PMID:27392435 | Slc4a8 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of SLC4A8 mRNA | CTD | PMID:26577399 | Slc4a8 | Rat | cytarabine | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of SLC4A8 mRNA | CTD | PMID:21198554 | Slc4a8 | Rat | dorsomorphin | multiple interactions | ISO | SLC4A8 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Slc4a8 | Rat | doxorubicin | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SLC4A8 mRNA | CTD | PMID:29803840 | Slc4a8 | Rat | ethanol | decreases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | Ethanol results in decreased expression of SLC4A8 mRNA | CTD | PMID:19167417 | Slc4a8 | Rat | ethanol | increases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | Ethanol results in increased expression of SLC4A8 mRNA | CTD | PMID:30319688 | Slc4a8 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SLC4A8 mRNA | CTD | PMID:33387578 | Slc4a8 | Rat | glyphosate | increases methylation | EXP | | 6480464 | Glyphosate results in increased methylation of SLC4A8 gene | CTD | PMID:31011160 | Slc4a8 | Rat | graphite | affects expression | EXP | | 6480464 | Graphite affects the expression of SLC4A8 mRNA | CTD | PMID:29933104 | Slc4a8 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of SLC4A8 gene | CTD | PMID:35440735 | Slc4a8 | Rat | nickel atom | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Nickel results in increased expression of SLC4A8 mRNA | CTD | PMID:25583101 | Slc4a8 | Rat | Nutlin-3 | multiple interactions | ISO | SLC4A8 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of SLC4A8 mRNA | CTD | PMID:38460933 | Slc4a8 | Rat | p-chloromercuribenzoic acid | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of SLC4A8 mRNA | CTD | PMID:26272509 | Slc4a8 | Rat | p-chloromercuribenzoic acid | multiple interactions | ISO | SLC4A8 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC4A8 mRNA | CTD | PMID:27188386 | Slc4a8 | Rat | paracetamol | affects expression | ISO | Slc4a8 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SLC4A8 mRNA | CTD | PMID:17562736 | Slc4a8 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SLC4A8 mRNA | CTD | PMID:33387578 | Slc4a8 | Rat | paracetamol | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SLC4A8 mRNA | CTD | PMID:22230336 | Slc4a8 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Slc4a8 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SLC4A8 mRNA | CTD | PMID:36331819 | Slc4a8 | Rat | phenylmercury acetate | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of SLC4A8 mRNA | CTD | PMID:26272509 | Slc4a8 | Rat | phenylmercury acetate | multiple interactions | ISO | SLC4A8 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC4A8 mRNA | CTD | PMID:27188386 | Slc4a8 | Rat | pirinixic acid | decreases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of SLC4A8 mRNA | CTD | PMID:20813756 | Slc4a8 | Rat | SB 431542 | multiple interactions | ISO | SLC4A8 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Slc4a8 | Rat | sodium arsenite | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SLC4A8 mRNA | CTD | PMID:34032870 | Slc4a8 | Rat | sulforaphane | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of SLC4A8 mRNA | CTD | PMID:31838189 | Slc4a8 | Rat | sunitinib | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of SLC4A8 mRNA | CTD | PMID:31533062 | Slc4a8 | Rat | tamoxifen | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Tamoxifen results in increased expression of SLC4A8 mRNA | CTD | PMID:17962382 | Slc4a8 | Rat | titanium dioxide | increases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SLC4A8 mRNA | CTD | PMID:23557971 | Slc4a8 | Rat | triphenyl phosphate | affects expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SLC4A8 mRNA | CTD | PMID:37042841 | Slc4a8 | Rat | trovafloxacin | decreases expression | ISO | Slc4a8 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of SLC4A8 mRNA | CTD | PMID:35537566 | Slc4a8 | Rat | valproic acid | decreases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SLC4A8 mRNA | CTD | PMID:24935251 | Slc4a8 | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of SLC4A8 mRNA | CTD | PMID:29427782 | Slc4a8 | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of SLC4A8 mRNA | CTD | PMID:29427782 | Slc4a8 | Rat | valproic acid | multiple interactions | ISO | SLC4A8 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC4A8 mRNA | CTD | PMID:27188386 | Slc4a8 | Rat | valproic acid | increases expression | ISO | SLC4A8 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SLC4A8 mRNA | CTD | PMID:23179753 more ... | Slc4a8 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of SLC4A8 mRNA | CTD | PMID:19015723 | Slc4a8 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of SLC4A8 gene | CTD | PMID:31079544 | Slc4a8 | Rat | zalcitabine | multiple interactions | EXP | | 6480464 | [gp120 protein and Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of SLC4A8 mRNA | CTD | PMID:18606552 | |