Niddm52 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Niddm52 (Non-insulin dependent diabetes mellitus QTL 52) Rattus norvegicus

Symbol: Niddm52
Name: Non-insulin dependent diabetes mellitus QTL 52
RGD ID: 724537
Previously known as: Nidd15/of
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: blood glucose level area under curve (AUC)   (CMO:0000350)    
LOD Score: Not Available
P Value: 0.02
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8782,111,245 - 95,485,241RGD_MAPPER_PIPELINE
mRatBN7.2780,221,299 - 93,595,843RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0788,365,265 - 102,588,450RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0788,393,619 - 103,159,589RGDRnor5.0
RGSC_v3.4785,089,895 - 98,955,278RGDRGSC3.4
RGSC_v3.1785,110,626 - 98,989,508RGD
Cross Type: intercross
Strains Crossed: F344/DuCrlCrlj OLETF/Got 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm52Ratglucose intolerance  IDA 619670 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm52Ratimpaired glucose tolerance  QTM 619670 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm52Ratblood glucose level area under curve (AUC)  IDA 619670 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm52Ratfasting  IDA 619670 RGD 
Niddm52Ratglucose solution, 2.8M  IDA 619670 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm52Ratoral glucose tolerance test  IDA 619670 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm52RatF344/DuCrlCrlj  IEA 619670 RGD 
Niddm52RatOLETF/Got  IEA 619670 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm52Ratblood glucose amount  IDA 619670 RGD 


#
Reference Title
Reference Citation
1. Identification of epistatic interactions involved in non-insulin-dependent diabetes mellitus in the Otsuka Long-Evans Tokushima Fatty rat. Yamada T, etal., Exp Anim 2001 Apr;50(2):115-23.


1 to 20 of 133 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
2324771Snw1-ps2SNW domain containing 1, pseudogene 278014008780332987Rat
1332703Or8i9-ps1olfactory receptor family 8 subfamily I member 9, pseudogene 178051937080519736Rat
1311883Trps1transcriptional repressor GATA binding 178191666882142733Rat
41396341LOC120093649uncharacterized LOC12009364978202511382045293Rat
7567645LOC102548590uncharacterized LOC10254859078223776582247335Rat
7548946LOC102548754uncharacterized LOC10254875478257677982604720Rat
11477543LOC10835158260S ribosomal protein L15 pseudogene78281934482828097Rat
735178Eif3heukaryotic translation initiation factor 3, subunit H78309103783174451Rat
1307179Utp23UTP23, small subunit processome component78318518783196652Rat
1594491Rps16-ps9ribosomal protein S16, pseudogene 978321863783219115Rat
1594529Rad21RAD21 cohesin complex component78328786783314810Rat
41137420LOC120093650uncharacterized LOC12009365078333277383340980Rat
631378Aardalanine and arginine rich domain containing protein78336447883369319Rat
1594490Rps3a-ps6ribosomal protein S3a, pseudogene 678341236983413165Rat
2323224Hmgn2l3high mobility group nucleosomal binding domain 2 like 378352004683520312Rat
1308282Slc30a8solute carrier family 30 member 878359199383627786Rat
41135575LOC120093651uncharacterized LOC12009365178372558483732362Rat
41223521LOC120094032U2 spliceosomal RNA78378336083783437Rat
41050819LOC120093918U6 spliceosomal RNA78379568283795784Rat
41210447LOC120093982small nucleolar RNA SNORA1778379870083798831Rat

1 to 20 of 133 rows
1 to 20 of 167 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10935D7Wox1413179359564793595780Ratregion
10936D7Arb520479359562793595833Ratregion
10937D7Wox1515979359562093595781Ratregion
10938D7Wox2911979359563393595754Ratregion
10939D7Mit2721079359563193595843Ratregion
34555D7Mgh614879141244491412594Ratregion
34713D7Mgh1623679125631191256547Ratregion
33648D7Mit513778022129980221436Ratregion
36015D7Rat2115579128113091281285Ratregion
37642D7Rat11224678519688685197132Ratregion
37710D7Rat19018879032403890324226Ratregion
37808D7Rat8612078315339283153512Ratregion
36442D7Rat2015778986737689867533Ratregion
35787D7Rat4217478400154684001720Ratregion
35841D7Rat1917679324212393242280Ratregion
39702D7Rat16012179350828593508404Ratregion
39938D7Rat14111778359195383592070Ratregion
40068D7Rat16117578400599684006171Ratregion
40116D7Rat16229378255597082556263Ratregion
40348D7Rat14015678989811689898272Ratregion
1 to 20 of 167 rows

Flank 1: (D7Mit5)
Rat AssemblyChrPosition (strand)Source
GRCr8782,111,245 - 82,111,382 (+)Marker Load Pipeline
mRatBN7.2780,221,299 - 80,221,436 (+)MAPPER
Rnor_6.0788,365,265 - 88,365,401NCBI
Rnor_5.0788,393,619 - 88,393,755UniSTS
RGSC_v3.4785,089,895 - 85,090,032RGD
RGSC_v3.4785,089,896 - 85,090,032UniSTS
RGSC_v3.1785,110,626 - 85,110,762RGD
Celera777,115,894 - 77,116,030UniSTS
RH 3.4 Map7539.2UniSTS
RH 3.4 Map7539.2RGD
RH 2.0 Map7467.1RGD
SHRSP x BN Map747.81RGD
FHH x ACI Map736.72RGD
Cytogenetic Map7 RGD
Flank 2: (D7Mit27)
Rat AssemblyChrPosition (strand)Source
GRCr8795,485,031 - 95,485,241 (+)Marker Load Pipeline
mRatBN7.2793,595,631 - 93,595,843 (+)MAPPER
Rnor_6.07102,588,240 - 102,588,450NCBI
Rnor_5.07103,159,379 - 103,159,589UniSTS
RGSC_v3.4798,955,068 - 98,955,278RGD
RGSC_v3.4798,955,069 - 98,955,278UniSTS
RGSC_v3.1798,989,298 - 98,989,508RGD
Celera790,265,830 - 90,266,033UniSTS
RH 3.4 Map7653.02RGD
RH 3.4 Map7653.02UniSTS
RH 2.0 Map7540.8RGD
Cytogenetic Map7q33UniSTS


1 to 10 of 54 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
10450828Scl79Serum cholesterol level QTL 793.50.001blood HDL cholesterol amount (VT:0000184)blood low density lipoprotein cholesterol level (CMO:0000053)789867376101773158Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat

1 to 10 of 54 rows


Database
Acc Id
Source(s)
NCBI Gene Niddm52

Note Type Note Reference
qtl_cross_type intercross  
qtl_general markers are approximately 10 cM apart; involved in epistatic interaction with Niddm53 and Niddm54 619670