Rad21 (RAD21 cohesin complex component) - Rat Genome Database

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Gene: Rad21 (RAD21 cohesin complex component) Rattus norvegicus
Analyze
Symbol: Rad21
Name: RAD21 cohesin complex component
RGD ID: 1594529
Description: Predicted to enable chromatin binding activity. Predicted to be involved in several processes, including protein localization to chromatin; regulation of cell cycle process; and replication-born double-strand break repair via sister chromatid exchange. Predicted to act upstream of or within chromatin looping. Predicted to be located in chromosome; midbody; and nuclear lumen. Predicted to be part of meiotic cohesin complex. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human RAD21 (RAD21 cohesin complex component); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: double-strand-break repair protein rad21 homolog; MGC116373; RAD21 homolog; RAD21 homolog (S. pombe); similar to HR21spA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2783,287,867 - 83,314,810 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl783,287,870 - 83,314,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx785,183,451 - 85,210,398 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0787,384,656 - 87,411,603 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0787,211,563 - 87,238,505 (-)NCBIRnor_WKY
Rnor_6.0791,511,755 - 91,538,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl791,511,756 - 91,538,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0792,155,546 - 92,182,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4788,267,648 - 88,294,703 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera780,164,565 - 80,191,459 (-)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-tribromophenol  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroperoxycyclophosphamide  (ISO)
4-hydroxyphenyl retinamide  (ISO)
afimoxifene  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Brevetoxin B  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP)
Echimidine  (ISO)
Enterolactone  (ISO)
finasteride  (EXP)
genistein  (ISO)
glafenine  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
Lasiocarpine  (ISO)
methapyrilene  (EXP)
Mezerein  (ISO)
microcystin-LR  (ISO)
monocrotaline  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphoramide mustard  (EXP)
pirinixic acid  (ISO)
quercetin  (ISO)
riddelliine  (ISO)
rotenone  (ISO)
saccharin  (ISO)
SB 431542  (ISO)
tetrachloromethane  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
zinc dichloride  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Polymorphisms in mitotic checkpoint-related genes can influence survival outcomes of early-stage non-small cell lung cancer. Kang HG, etal., Oncotarget. 2017 Jun 27;8(37):61777-61785. doi: 10.18632/oncotarget.18693. eCollection 2017 Sep 22.
3. Cell Cycle Genes Are Potential Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma. Liping X, etal., Biomed Res Int. 2020 Jun 7;2020:6206157. doi: 10.1155/2020/6206157. eCollection 2020.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. MiR-320b/RAD21 axis affects hepatocellular carcinoma radiosensitivity to ionizing radiation treatment through DNA damage repair signaling. Wang J, etal., Cancer Sci. 2021 Feb;112(2):575-588. doi: 10.1111/cas.14751. Epub 2020 Dec 31.
10. Correlation of invasion and metastasis of cancer cells, and expression of the RAD21 gene in oral squamous cell carcinoma. Yamamoto G, etal., Virchows Arch. 2006 Apr;448(4):435-41. doi: 10.1007/s00428-005-0132-y. Epub 2006 Jan 14.
11. Genomic and regulatory characteristics of significant transcription factors in colorectal cancer metastasis. Zhou B and Guo R, Sci Rep. 2018 Dec 13;8(1):17836. doi: 10.1038/s41598-018-36168-8.
Additional References at PubMed
PMID:10375619   PMID:11590136   PMID:12477932   PMID:18499658   PMID:19468298   PMID:19946888   PMID:21111234   PMID:22419665   PMID:22628566   PMID:22780989   PMID:23920377   PMID:24797475  
PMID:31505169   PMID:33741460  


Genomics

Comparative Map Data
Rad21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2783,287,867 - 83,314,810 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl783,287,870 - 83,314,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx785,183,451 - 85,210,398 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0787,384,656 - 87,411,603 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0787,211,563 - 87,238,505 (-)NCBIRnor_WKY
Rnor_6.0791,511,755 - 91,538,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl791,511,756 - 91,538,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0792,155,546 - 92,182,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4788,267,648 - 88,294,703 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera780,164,565 - 80,191,459 (-)NCBICelera
Cytogenetic Map7q31NCBI
RAD21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388116,845,934 - 116,874,776 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl8116,845,934 - 116,874,776 (-)EnsemblGRCh38hg38GRCh38
GRCh378117,858,173 - 117,887,015 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368117,927,355 - 117,956,182 (-)NCBINCBI36Build 36hg18NCBI36
Build 348117,927,354 - 117,956,182NCBI
Celera8114,046,862 - 114,075,794 (-)NCBICelera
Cytogenetic Map8q24.11NCBI
HuRef8113,184,591 - 113,213,523 (-)NCBIHuRef
CHM1_18117,898,409 - 117,927,335 (-)NCBICHM1_1
T2T-CHM13v2.08117,974,085 - 118,002,938 (-)NCBIT2T-CHM13v2.0
Rad21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391551,826,000 - 51,856,934 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1551,825,636 - 51,855,143 (-)EnsemblGRCm39 Ensembl
GRCm381551,962,604 - 51,993,538 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1551,962,240 - 51,991,747 (-)EnsemblGRCm38mm10GRCm38
MGSCv371551,794,150 - 51,823,306 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361551,792,680 - 51,821,636 (-)NCBIMGSCv36mm8
Celera1553,535,633 - 53,555,853 (-)NCBICelera
Cytogenetic Map15CNCBI
Rad21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541722,941,479 - 22,966,837 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541722,941,549 - 22,966,395 (-)NCBIChiLan1.0ChiLan1.0
RAD21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18116,063,503 - 116,092,421 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8116,063,503 - 116,092,421 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v08113,520,456 - 113,549,339 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
RAD21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11316,337,563 - 16,368,041 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1316,338,972 - 16,368,035 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1316,338,678 - 16,369,154 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01316,626,236 - 16,656,848 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1316,626,236 - 16,656,850 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11316,369,666 - 16,400,273 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01316,469,992 - 16,500,602 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01316,711,252 - 16,741,853 (-)NCBIUU_Cfam_GSD_1.0
Rad21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530321,951,734 - 21,978,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647029,377,734 - 29,407,312 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647029,377,793 - 29,403,422 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl421,772,855 - 21,802,715 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1421,772,821 - 21,802,453 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2423,059,570 - 23,262,558 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAD21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18111,486,356 - 111,515,641 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8111,486,048 - 111,507,729 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603928,811,005 - 28,840,566 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rad21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476315,131,005 - 15,158,155 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476315,131,106 - 15,157,512 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rad21
122 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:190
Count of miRNA genes:149
Interacting mature miRNAs:172
Transcripts:ENSRNOT00000006209
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
724537Niddm52Non-insulin dependent diabetes mellitus QTL 520.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)78022129993595843Rat
1641908Teswt1Testicular weight QTL 13.28testis mass (VT:1000644)both testes wet weight (CMO:0000175)78022129994811326Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat

Markers in Region
RH131367  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2783,293,712 - 83,293,892 (+)MAPPERmRatBN7.2
Rnor_6.0791,517,601 - 91,517,780NCBIRnor6.0
Rnor_5.0792,161,392 - 92,161,571UniSTSRnor5.0
RGSC_v3.4788,273,494 - 88,273,673UniSTSRGSC3.4
Celera780,170,411 - 80,170,590UniSTS
RH 3.4 Map7550.3UniSTS
Cytogenetic Map7q31UniSTS
RH137734  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2783,288,539 - 83,288,693 (+)MAPPERmRatBN7.2
Rnor_6.0791,512,428 - 91,512,581NCBIRnor6.0
Rnor_5.0792,156,219 - 92,156,372UniSTSRnor5.0
RGSC_v3.4788,268,321 - 88,268,474UniSTSRGSC3.4
Celera780,165,238 - 80,165,391UniSTS
RH 3.4 Map7550.4UniSTS
Cytogenetic Map7q31UniSTS
RH134178  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2783,287,932 - 83,288,113 (+)MAPPERmRatBN7.2
Rnor_6.0791,511,821 - 91,512,001NCBIRnor6.0
Rnor_5.0792,155,612 - 92,155,792UniSTSRnor5.0
RGSC_v3.4788,267,714 - 88,267,894UniSTSRGSC3.4
Celera780,164,631 - 80,164,811UniSTS
RH 3.4 Map7549.1UniSTS
Cytogenetic Map7q31UniSTS
RH139481  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2783,288,539 - 83,288,756 (+)MAPPERmRatBN7.2
Rnor_6.0791,512,428 - 91,512,644NCBIRnor6.0
Rnor_5.0792,156,219 - 92,156,435UniSTSRnor5.0
RGSC_v3.4788,268,321 - 88,268,537UniSTSRGSC3.4
Celera780,165,238 - 80,165,454UniSTS
RH 3.4 Map7551.8UniSTS
Cytogenetic Map7q31UniSTS
AW530029  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2783,316,640 - 83,316,791 (+)MAPPERmRatBN7.2
Rnor_6.0791,540,504 - 91,540,654NCBIRnor6.0
Rnor_5.0792,184,580 - 92,184,730UniSTSRnor5.0
RGSC_v3.4788,296,534 - 88,296,684UniSTSRGSC3.4
Celera780,193,290 - 80,193,440UniSTS
RH 3.4 Map7541.8UniSTS
Cytogenetic Map7q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006209   ⟹   ENSRNOP00000006209
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl783,287,870 - 83,314,817 (-)Ensembl
Rnor_6.0 Ensembl791,511,756 - 91,538,673 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116638   ⟹   ENSRNOP00000095133
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl783,288,697 - 83,314,805 (-)Ensembl
RefSeq Acc Id: NM_001025701   ⟹   NP_001020872
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2783,287,867 - 83,314,810 (-)NCBI
Rnor_6.0791,511,755 - 91,538,673 (-)NCBI
Rnor_5.0792,155,546 - 92,182,749 (-)NCBI
RGSC_v3.4788,267,648 - 88,294,703 (-)RGD
Celera780,164,565 - 80,191,459 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001020872 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH99200 (Get FASTA)   NCBI Sequence Viewer  
  EDM16276 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001020872   ⟸   NM_001025701
- UniProtKB: Q4KLH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006209   ⟸   ENSRNOT00000006209
RefSeq Acc Id: ENSRNOP00000095133   ⟸   ENSRNOT00000116638
Protein Domains
Rad21_Rec8   Rad21_Rec8_N

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KLH7-F1-model_v2 AlphaFold Q4KLH7 1-635 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695323
Promoter ID:EPDNEW_R5848
Type:initiation region
Name:Rad21_1
Description:RAD21 cohesin complex component
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0791,538,660 - 91,538,720EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1594529 AgrOrtholog
BioCyc Gene G2FUF-33427 BioCyc
Ensembl Genes ENSRNOG00000004420 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006209.6 UniProtKB/TrEMBL
  ENSRNOP00000095133 ENTREZGENE
  ENSRNOP00000095133.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006209.6 UniProtKB/TrEMBL
  ENSRNOT00000116638 ENTREZGENE
  ENSRNOT00000116638.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.580 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7384021 IMAGE-MGC_LOAD
InterPro Rad21/Rec8-like UniProtKB/TrEMBL
  Rad21/Rec8_C UniProtKB/TrEMBL
  Rad21_Rec8_N UniProtKB/TrEMBL
  ScpA-like_C UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:314949 UniProtKB/TrEMBL
MGC_CLONE MGC:116373 IMAGE-MGC_LOAD
NCBI Gene 314949 ENTREZGENE
PANTHER PTHR12585 UniProtKB/TrEMBL
Pfam Rad21_Rec8 UniProtKB/TrEMBL
  Rad21_Rec8_N UniProtKB/TrEMBL
PhenoGen Rad21 PhenoGen
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt F7EK71_RAT UniProtKB/TrEMBL
  Q4KLH7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-01 Rad21  RAD21 cohesin complex component  Rad21  RAD21 homolog (S. pombe)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Rad21  RAD21 homolog (S. pombe)  MGC116373  similar to HR21spA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 MGC116373  similar to HR21spA      Symbol and Name status set to provisional 70820 PROVISIONAL