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Gene: RAD21 (RAD21 cohesin complex component) Homo sapiens
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Symbol: RAD21
Name: RAD21 cohesin complex component
Description: Predicted to have chromatin binding activity. Involved in positive regulation of sister chromatid cohesion; protein localization to chromatin; and regulation of transcription by RNA polymerase II. Localizes to the cohesin complex; nuclear matrix; and nucleoplasm. Implicated in Cornelia de Lange syndrome 4.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDLS4; double-strand-break repair protein rad21 homolog; FLJ25655; FLJ40596; hHR21; HR21; HRAD21; KIAA0078; kleisin; MCD1; MGS; nuclear matrix protein 1; NXP-1; NXP1; protein involved in DNA double-strand break repair; RAD21 homolog; SCC1; SCC1 homolog; sister chromatid cohesion 1
Orthologs:
Mus musculus (house mouse) : Rad21 (RAD21 cohesin complex component)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rad21 (RAD21 cohesin complex component)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rad21 (RAD21 cohesin complex component)
Pan paniscus (bonobo/pygmy chimpanzee) : RAD21 (RAD21 cohesin complex component)
Canis lupus familiaris (dog) : RAD21 (RAD21 cohesin complex component)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rad21 (RAD21 cohesin complex component)
Sus scrofa (pig) : RAD21 (RAD21 cohesin complex component)
Chlorocebus sabaeus (green monkey) : RAD21 (RAD21 cohesin complex component)
Heterocephalus glaber (naked mole-rat) : Rad21 (RAD21 cohesin complex component)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl8116,845,934 - 116,874,776 (-)Ensembl
GRCh38 Ensembl8116,845,935 - 116,874,866 (-)Ensembl
GRCh388116,845,934 - 116,874,776 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378117,858,173 - 117,887,105 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368117,927,355 - 117,956,182 (-)NCBINCBI36hg18NCBI36
Build 348117,927,354 - 117,956,182NCBI
Celera8114,046,862 - 114,075,794 (-)NCBI
Cytogenetic Map8q24.11NCBI
HuRef8113,184,591 - 113,213,523 (-)NCBIHuRef
CHM1_18117,898,409 - 117,927,335 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RAD21
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317642
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.