Rad21 (RAD21 cohesin complex component) - Rat Genome Database

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Gene: Rad21 (RAD21 cohesin complex component) Mus musculus
Analyze
Symbol: Rad21
Name: RAD21 cohesin complex component
RGD ID: 1317643
MGI Page MGI
Description: Predicted to enable DNA-binding transcription factor binding activity; chromatin binding activity; and lncRNA binding activity. Involved in negative regulation of G2/M transition of mitotic cell cycle and negative regulation of mitotic metaphase/anaphase transition. Acts upstream of or within chromatin looping. Located in chromosome, centromeric region and condensed nuclear chromosome. Part of chromatin and cohesin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; endometrial cancer; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human RAD21 (RAD21 cohesin complex component).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: double-strand-break repair protein rad21 homolog; MGC150311; MGC150312; mHR21; mKIAA0078; pokeweed agglutinin-binding protein 29; PW29; RAD21 homolog; SCC; SCC1; SCC1 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm8473  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391551,826,000 - 51,856,934 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1551,825,636 - 51,855,143 (-)EnsemblGRCm39 Ensembl
GRCm381551,962,604 - 51,993,538 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1551,962,240 - 51,991,747 (-)EnsemblGRCm38mm10GRCm38
MGSCv371551,794,150 - 51,823,306 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361551,792,680 - 51,821,636 (-)NCBIMGSCv36mm8
Celera1553,535,633 - 53,555,853 (-)NCBICelera
Cytogenetic Map15CNCBI
cM Map1519.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-butoxyethanol  (EXP)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroperoxycyclophosphamide  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (ISO)
afimoxifene  (ISO)
amitrole  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
Brevetoxin B  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Echimidine  (ISO)
Enterolactone  (ISO)
finasteride  (ISO)
genistein  (ISO)
glafenine  (ISO)
glycyrrhizinic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
Lasiocarpine  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
Mezerein  (EXP)
microcystin-LR  (EXP)
monocrotaline  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (EXP)
okadaic acid  (EXP)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
phosphoramide mustard  (ISO)
pirinixic acid  (EXP)
quercetin  (ISO)
riddelliine  (ISO)
rotenone  (ISO)
saccharin  (EXP)
SB 431542  (ISO)
sulfadimethoxine  (ISO)
tetrachloromethane  (EXP)
topotecan  (ISO)
torcetrapib  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
zinc dichloride  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. PPARγ/RAD21 alleviates peripheral secondary brain injury in rat cerebral hemorrhage model through promoting M2 polarization of microglial cells. Jiao Y, etal., Int Immunopharmacol. 2023 Jan;114:109572. doi: 10.1016/j.intimp.2022.109572. Epub 2022 Dec 18.
2. Mechanism of glycyrrhizic acid inhibition of Kaposi's sarcoma-associated herpesvirus: disruption of CTCF-cohesin-mediated RNA polymerase II pausing and sister chromatid cohesion. Kang H and Lieberman PM, J Virol. 2011 Nov;85(21):11159-69. doi: 10.1128/JVI.00720-11. Epub 2011 Aug 31.
3. Polymorphisms in mitotic checkpoint-related genes can influence survival outcomes of early-stage non-small cell lung cancer. Kang HG, etal., Oncotarget. 2017 Jun 27;8(37):61777-61785. doi: 10.18632/oncotarget.18693. eCollection 2017 Sep 22.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. [Endometrial cancer in young women--clinical and molecular aspects]. Lapińska-Szumczyk S, etal., Ginekol Pol. 2014 Oct;85(10):754-9.
6. LncRNA MIAT activates vascular endothelial growth factor A through RAD21 to promote nerve injury repair in acute spinal cord injury. Li D, etal., Mol Cell Endocrinol. 2021 May 15;528:111244. doi: 10.1016/j.mce.2021.111244. Epub 2021 Mar 17.
7. Cell Cycle Genes Are Potential Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma. Liping X, etal., Biomed Res Int. 2020 Jun 7;2020:6206157. doi: 10.1155/2020/6206157. eCollection 2020.
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Aug 31;10(4):167-80.
10. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. MiR-320b/RAD21 axis affects hepatocellular carcinoma radiosensitivity to ionizing radiation treatment through DNA damage repair signaling. Wang J, etal., Cancer Sci. 2021 Feb;112(2):575-588. doi: 10.1111/cas.14751. Epub 2020 Dec 31.
17. Correlation of invasion and metastasis of cancer cells, and expression of the RAD21 gene in oral squamous cell carcinoma. Yamamoto G, etal., Virchows Arch. 2006 Apr;448(4):435-41. doi: 10.1007/s00428-005-0132-y. Epub 2006 Jan 14.
18. Genomic and regulatory characteristics of significant transcription factors in colorectal cancer metastasis. Zhou B and Guo R, Sci Rep. 2018 Dec 13;8(1):17836. doi: 10.1038/s41598-018-36168-8.
Additional References at PubMed
PMID:271968   PMID:7892263   PMID:8521526   PMID:8812457   PMID:9108238   PMID:10349636   PMID:10375619   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11471062   PMID:12034751  
PMID:12130806   PMID:12417729   PMID:12477932   PMID:14610273   PMID:14681479   PMID:14970259   PMID:15031719   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18180366   PMID:18219272  
PMID:18799693   PMID:19109133   PMID:20360068   PMID:20711430   PMID:20971813   PMID:21242291   PMID:21267068   PMID:21274006   PMID:21589869   PMID:21699228   PMID:21743440   PMID:21832993  
PMID:21873635   PMID:22075476   PMID:22083510   PMID:22164254   PMID:22415368   PMID:22419665   PMID:22550178   PMID:22560297   PMID:22711701   PMID:22780989   PMID:22922362   PMID:23920377  
PMID:23937658   PMID:24185899   PMID:24291092   PMID:24457600   PMID:24797475   PMID:25245017   PMID:25561493   PMID:25737280   PMID:26167872   PMID:26496610   PMID:26919979   PMID:27321927  
PMID:27554164   PMID:27916276   PMID:28863138   PMID:29217590   PMID:30069982   PMID:30127433   PMID:30955885   PMID:31040226   PMID:31837995   PMID:32328639   PMID:34006846   PMID:34266888  
PMID:34746147   PMID:35471149   PMID:35896525   PMID:36201246   PMID:36571142   PMID:37347873   PMID:37534584  


Genomics

Comparative Map Data
Rad21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391551,826,000 - 51,856,934 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1551,825,636 - 51,855,143 (-)EnsemblGRCm39 Ensembl
GRCm381551,962,604 - 51,993,538 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1551,962,240 - 51,991,747 (-)EnsemblGRCm38mm10GRCm38
MGSCv371551,794,150 - 51,823,306 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361551,792,680 - 51,821,636 (-)NCBIMGSCv36mm8
Celera1553,535,633 - 53,555,853 (-)NCBICelera
Cytogenetic Map15CNCBI
cM Map1519.54NCBI
RAD21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388116,845,934 - 116,874,776 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8116,845,934 - 116,874,776 (-)EnsemblGRCh38hg38GRCh38
GRCh378117,858,173 - 117,887,015 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368117,927,355 - 117,956,182 (-)NCBINCBI36Build 36hg18NCBI36
Build 348117,927,354 - 117,956,182NCBI
Celera8114,046,862 - 114,075,794 (-)NCBICelera
Cytogenetic Map8q24.11NCBI
HuRef8113,184,591 - 113,213,523 (-)NCBIHuRef
CHM1_18117,898,409 - 117,927,335 (-)NCBICHM1_1
T2T-CHM13v2.08117,974,085 - 118,002,938 (-)NCBIT2T-CHM13v2.0
Rad21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8785,177,715 - 85,204,657 (-)NCBIGRCr8
mRatBN7.2783,287,867 - 83,314,810 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl783,287,870 - 83,314,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx785,183,451 - 85,210,398 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0787,384,656 - 87,411,603 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0787,211,563 - 87,238,505 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0791,511,755 - 91,538,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl791,511,756 - 91,538,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0792,155,546 - 92,182,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4788,267,648 - 88,294,703 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera780,164,565 - 80,191,459 (-)NCBICelera
Cytogenetic Map7q31NCBI
Rad21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541722,941,479 - 22,966,837 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541722,941,549 - 22,966,395 (-)NCBIChiLan1.0ChiLan1.0
RAD21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27134,252,362 - 134,281,273 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18109,767,758 - 109,796,718 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08113,520,456 - 113,549,339 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18116,063,503 - 116,092,421 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8116,063,503 - 116,092,421 (-)Ensemblpanpan1.1panPan2
RAD21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11316,337,563 - 16,368,041 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1316,338,972 - 16,368,035 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1316,338,678 - 16,369,154 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01316,626,236 - 16,656,848 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1316,626,236 - 16,656,850 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11316,369,666 - 16,400,273 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01316,469,992 - 16,500,602 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01316,711,252 - 16,741,853 (-)NCBIUU_Cfam_GSD_1.0
Rad21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530321,951,734 - 21,978,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647029,377,734 - 29,407,312 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647029,377,793 - 29,403,422 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl421,772,855 - 21,802,715 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1421,772,821 - 21,802,453 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2423,059,570 - 23,262,558 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAD21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18111,486,356 - 111,515,641 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8111,486,048 - 111,507,729 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603928,811,005 - 28,840,566 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rad21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476315,131,005 - 15,158,155 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476315,131,106 - 15,157,512 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rad21
984 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:469
Count of miRNA genes:351
Interacting mature miRNAs:403
Transcripts:ENSMUST00000022927
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15347438971197538Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15612948168271849Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15612948171471849Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15612948172471849Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
27095940Ulnl8_mulna length 8, 10 week (mouse)15722948155263396Mouse
27226759Feml17_mfemur length 17, 10 week (mouse)15762948155263396Mouse
27226755Feml22_mfemur length 22, 16 week (mouse)15762948159271849Mouse
4141192Ssrq2_mstress response QTL 2 (mouse)Not determined927302256186850Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
14928313Manh78_mmandible shape 78 (mouse)152148464155484641Mouse
12859289Criq3_mCitrobacter rodentium infection QTL 3 (mouse)152259376556593765Mouse
4142160Femwf10_mfemur work to failure 10 (mouse)Not determined2289301456893160Mouse
1301557Bbaa22_mB.burgdorferi-associated arthritis 22 (mouse)Not determined152446257258462805Mouse
1300967Bdt6_mbone density traits 6 (mouse)Not determined152529580659295928Mouse
4141409Radsvq1_mradiation sensitivity QTL 1 (mouse)Not determined2548497859484978Mouse
1300772Bglq16_mbody growth late QTL 16 (mouse)Not determined152631178060311880Mouse
1301345Bgeq14_mbody growth early QTL 14 (mouse)Not determined152631178060311880Mouse
1357514Mbis3_mMycobacterium bovis-induced systemic lupus erythematosus 3 (mouse)Not determined162631178060311880Mouse
1301406Egrd2_mearly growth rate (mouse)Not determined152631178060311880Mouse
27226800Scvln20_msacral vertebrae length 2, 16 week (mouse)152660008666371849Mouse
1301450Bpq6_mblood pressure QTL 6 (mouse)Not determined152828264662282739Mouse
1357512Bsbob5_mBSB obesity 5 (mouse)Not determined152828264662282739Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930014676084200Mouse
26884452Sklq17_mskull length QTL 17, 16 week (mouse)153020014657963396Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
1300578Cd8ts3_mCD8 T cell subset 3 (mouse)Not determined153400469468004804Mouse
1301324Cdif_mcolor difference (mouse)Not determined153597590669976019Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
12792977Tbmd1_mtibial bone mineral density 1, males only (mouse)153807048952031841Mouse
1301580Hrq2_mheart rate quantitative locus 2 (mouse)Not determined153910039573100593Mouse
1300949Lore5_mloss of righting induced by ethanol 5 (mouse)Not determined154001944158022297Mouse
4142459Lfnq3_mlung function QTL 3 (mouse)Not determined4017702272372580Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154455331378553437Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154485914178859281Mouse
26884420Cvht6_mcranial vault height 6, 10 week (mouse)154556339669171849Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154638964680389845Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154638964680389845Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154730633481306479Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
25394541Skmw81_mskeletal muscle weight 81, EDL (mouse)155065907253149074Mouse
1357661Eae2b_msusceptibility to experimental allergic encephalomyelitis 2b (mouse)Not determined155100469464944308Mouse
1301779Dpml_mdopamine loss (mouse)Not determined155100469476794493Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
35673313Ari8_mantibody response to influenza 8, day 15-45, TotalG (mouse)155146339654863396Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse

Markers in Region
43.MMHAP79FLG4.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381551,988,766 - 51,988,942UniSTSGRCm38
MGSCv371551,820,312 - 51,820,488UniSTSGRCm37
Celera1553,561,914 - 53,562,090UniSTS
Cytogenetic Map15D3UniSTS
Whitehead_YAC15 UniSTS
D49429  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381551,963,722 - 51,963,796UniSTSGRCm38
MGSCv371551,795,268 - 51,795,342UniSTSGRCm37
Celera1553,536,751 - 53,536,825UniSTS
Cytogenetic Map15D3UniSTS
Whitehead_YAC15 UniSTS
Rad21  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381551,962,681 - 51,962,800UniSTSGRCm38
MGSCv371551,794,227 - 51,794,346UniSTSGRCm37
Celera1553,535,710 - 53,535,829UniSTS
Cytogenetic Map15D3UniSTS
cM Map15 UniSTS
WI-14191  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381551,962,648 - 51,962,755UniSTSGRCm38
MGSCv371551,794,194 - 51,794,301UniSTSGRCm37
Celera1553,535,677 - 53,535,784UniSTS
Cytogenetic Map15D3UniSTS
Rad21  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15D3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001411716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC160550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF332085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF332086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK128984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC129916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC129917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ072039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D37790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X98293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000022927   ⟹   ENSMUSP00000022927
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1551,825,636 - 51,855,143 (-)Ensembl
GRCm38.p6 Ensembl1551,962,240 - 51,991,747 (-)Ensembl
RefSeq Acc Id: ENSMUST00000226529   ⟹   ENSMUSP00000154815
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1551,837,233 - 51,854,906 (-)Ensembl
GRCm38.p6 Ensembl1551,973,837 - 51,991,510 (-)Ensembl
RefSeq Acc Id: NM_001411716   ⟹   NP_001398645
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391551,826,000 - 51,855,121 (-)NCBI
RefSeq Acc Id: NM_009009   ⟹   NP_033035
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391551,826,000 - 51,855,121 (-)NCBI
GRCm381551,962,604 - 51,991,760 (-)NCBI
MGSCv371551,794,150 - 51,823,306 (-)RGD
Celera1553,535,633 - 53,555,853 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006520644   ⟹   XP_006520707
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391551,826,000 - 51,856,934 (-)NCBI
GRCm381551,962,604 - 51,993,538 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_033035   ⟸   NM_009009
- UniProtKB: Q91VB9 (UniProtKB/Swiss-Prot),   Q810A8 (UniProtKB/Swiss-Prot),   Q3TQ09 (UniProtKB/Swiss-Prot),   P70219 (UniProtKB/Swiss-Prot),   Q9DBU4 (UniProtKB/Swiss-Prot),   Q61550 (UniProtKB/Swiss-Prot),   Q3TG35 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006520707   ⟸   XM_006520644
- Peptide Label: isoform X1
- UniProtKB: Q91VB9 (UniProtKB/Swiss-Prot),   Q810A8 (UniProtKB/Swiss-Prot),   Q3TQ09 (UniProtKB/Swiss-Prot),   P70219 (UniProtKB/Swiss-Prot),   Q9DBU4 (UniProtKB/Swiss-Prot),   Q61550 (UniProtKB/Swiss-Prot),   Q3TG35 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000022927   ⟸   ENSMUST00000022927
RefSeq Acc Id: ENSMUSP00000154815   ⟸   ENSMUST00000226529
RefSeq Acc Id: NP_001398645   ⟸   NM_001411716
- UniProtKB: Q91VB9 (UniProtKB/Swiss-Prot),   Q810A8 (UniProtKB/Swiss-Prot),   Q61550 (UniProtKB/Swiss-Prot),   Q3TQ09 (UniProtKB/Swiss-Prot),   P70219 (UniProtKB/Swiss-Prot),   Q9DBU4 (UniProtKB/Swiss-Prot),   Q3TG35 (UniProtKB/TrEMBL)
Protein Domains
Rad21/Rec8-like protein C-terminal eukaryotic   Rad21/Rec8-like protein N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61550-F1-model_v2 AlphaFold Q61550 1-635 view protein structure

Promoters
RGD ID:6826398
Promoter ID:MM_KWN:18419
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   MEF_B4,   MEF_B6
Transcripts:NM_009009
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361551,822,891 - 51,823,647 (-)MPROMDB
RGD ID:8683722
Promoter ID:EPDNEW_M19891
Type:initiation region
Name:Rad21_1
Description:Mus musculus RAD21 cohesin complex component , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381551,991,708 - 51,991,768EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108016 AgrOrtholog
Ensembl Genes ENSMUSG00000022314 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022927 ENTREZGENE
  ENSMUST00000022927.11 UniProtKB/Swiss-Prot
  ENSMUST00000226529.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.580 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NXP1_M-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rad21/Rec8-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rad21/Rec8_C_eu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rad21_Rec8_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ScpA-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19357 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:108016 ENTREZGENE
NCBI Gene 19357 ENTREZGENE
PANTHER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21 HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12585 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Rad21_Rec8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rad21_Rec8_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rad21 PhenoGen
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BS25_MOUSE UniProtKB/TrEMBL
  A1L366_MOUSE UniProtKB/TrEMBL
  A1L367_MOUSE UniProtKB/TrEMBL
  P70219 ENTREZGENE
  Q3TG35 ENTREZGENE, UniProtKB/TrEMBL
  Q3TQ09 ENTREZGENE
  Q3UTE4_MOUSE UniProtKB/TrEMBL
  Q61550 ENTREZGENE
  Q6ZQJ6_MOUSE UniProtKB/TrEMBL
  Q810A8 ENTREZGENE
  Q91VB9 ENTREZGENE
  Q9DBU4 ENTREZGENE
  RAD21_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary P70219 UniProtKB/Swiss-Prot
  Q3TQ09 UniProtKB/Swiss-Prot
  Q810A8 UniProtKB/Swiss-Prot
  Q91VB9 UniProtKB/Swiss-Prot
  Q9DBU4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-02 Rad21  RAD21 cohesin complex component    RAD21 homolog (S. pombe)  Symbol and/or name change 5135510 APPROVED