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Gene: Deptor (DEP domain containing MTOR-interacting protein) Rattus norvegicus

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Symbol:

Deptor

Name:

DEP domain containing MTOR-interacting protein

RGD ID:

1561030

Description:

Predicted to enable GTPase regulator activity; phosphatidic acid binding activity; and protein serine/threonine kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and negative regulation of protein kinase activity. Predicted to be active in lysosomal membrane and plasma membrane. Orthologous to human DEPTOR (DEP domain containing MTOR interacting protein); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

DEP domain containing 6; Depdc6; hypothetical protein LOC100359815; LOC100359815; LOC102547145; LOC314979; RGD1561030; similar to DEP domain containing 6; uncharacterized LOC102547145

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	88,404,745 - 88,574,065 (+)	NCBI		GRCr8
mRatBN7.2	7	86,514,859 - 86,668,817 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	86,514,988 - 86,667,773 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	7	94,795,161 - 95,000,750 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	94,795,214 - 94,995,809 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	95,520,754 - 95,625,869 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	91,675,825 - 91,742,576 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	83,308,700 - 83,462,454 (+)	NCBI		Celera
Cytogenetic Map	7	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hereditary multiple exostoses (ISO)

trichorhinophalangeal syndrome type I (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

amphotericin B (ISO)

aristolochic acid A (ISO)

atrazine (EXP)

bafilomycin A1 (EXP)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bicalutamide (ISO)

bilirubin IXalpha (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

buspirone (EXP)

cadmium dichloride (EXP,ISO)

cannabidiol (EXP,ISO)

carbon nanotube (ISO)

chloroprene (EXP)

choline (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cytarabine (ISO)

deoxynivalenol (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

diethylstilbestrol (ISO)

Doramectin (EXP)

dorsomorphin (EXP,ISO)

endosulfan (EXP)

Enterolactone (ISO)

entinostat (ISO)

epoxiconazole (ISO)

fenthion (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

genistein (ISO)

hydroquinone (ISO)

indometacin (ISO)

L-methionine (ISO)

lead(0) (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

menadione (ISO)

metformin (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

methylmercury chloride (ISO)

nickel atom (ISO)

nickel dichloride (EXP)

ozone (ISO)

panobinostat (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

progesterone (ISO)

propiconazole (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sirolimus (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sotorasib (ISO)

succimer (ISO)

sulforaphane (ISO)

tamoxifen (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trametinib (ISO)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vorinostat (ISO)

zearalenone (ISO)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IBA)

intracellular signal transduction (IEA)

negative regulation of cell size (ISO)

negative regulation of protein kinase activity (ISO)

negative regulation of TOR signaling (ISO)

negative regulation of TORC1 signaling (IBA,ISO)

negative regulation of TORC2 signaling (IBA,ISO)

positive regulation of autophagy (ISO)

regulation of extrinsic apoptotic signaling pathway (ISO)

Cellular Component

lysosomal membrane (ISO)

plasma membrane (IBA)

Molecular Function

GTPase activator activity (IBA)

guanyl-nucleotide exchange factor activity (IBA)

phosphatidic acid binding (ISO)

protein binding (ISO)

protein kinase inhibitor activity (ISO)

protein serine/threonine kinase inhibitor activity (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mTOR signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	mTOR signaling in growth control and disease.	Laplante M and Sabatini DM, Cell. 2012 Apr 13;149(2):274-93. doi: 10.1016/j.cell.2012.03.017.
3.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19446321	PMID:25159114	PMID:29397070	PMID:31176743

Genomics

Comparative Map Data

Deptor
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	88,404,745 - 88,574,065 (+)	NCBI		GRCr8
mRatBN7.2	7	86,514,859 - 86,668,817 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	86,514,988 - 86,667,773 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	7	94,795,161 - 95,000,750 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	94,795,214 - 94,995,809 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	95,520,754 - 95,625,869 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	91,675,825 - 91,742,576 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	83,308,700 - 83,462,454 (+)	NCBI		Celera
Cytogenetic Map	7	q32	NCBI

DEPTOR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	119,873,722 - 120,050,918 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	119,873,717 - 120,050,918 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	120,885,962 - 121,063,157 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	120,955,146 - 121,131,939 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	120,955,145 - 121,131,937	NCBI
Celera	8	117,075,022 - 117,252,280 (+)	NCBI		Celera
Cytogenetic Map	8	q24.12	NCBI
HuRef	8	116,206,531 - 116,383,857 (+)	NCBI		HuRef
CHM1_1	8	120,926,730 - 121,103,852 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	121,002,533 - 121,179,716 (+)	NCBI		T2T-CHM13v2.0

Deptor
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	54,975,824 - 55,122,667 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	54,975,713 - 55,122,667 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	55,112,317 - 55,259,273 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	55,112,317 - 55,259,271 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	54,944,038 - 55,085,757 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	54,942,566 - 55,084,285 (+)	NCBI		MGSCv36	mm8
Celera	15	56,652,905 - 56,794,634 (+)	NCBI		Celera
Cytogenetic Map	15	D1	NCBI
cM Map	15	21.96	NCBI

Deptor
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	25,538,578 - 25,566,772 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955417	25,538,609 - 25,563,374 (+)	NCBI	ChiLan1.0	ChiLan1.0

DEPTOR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	137,299,270 - 137,484,402 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	112,811,180 - 112,996,385 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	116,563,935 - 116,743,843 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	119,311,942 - 119,492,127 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	119,311,942 - 119,492,127 (+)	Ensembl	panpan1.1		panPan2

DEPTOR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	18,859,526 - 18,993,464 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	18,859,634 - 18,988,583 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	18,872,396 - 19,007,464 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	19,188,815 - 19,323,823 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	19,188,882 - 19,320,795 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	18,915,849 - 19,051,161 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	19,015,161 - 19,150,366 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	19,246,027 - 19,381,218 (+)	NCBI		UU_Cfam_GSD_1.0

Deptor
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	19,272,854 - 19,411,349 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	26,704,021 - 26,837,470 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	26,698,707 - 26,837,470 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DEPTOR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	18,976,743 - 19,180,117 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	18,969,509 - 19,180,131 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	20,001,488 - 20,186,277 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DEPTOR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	114,442,212 - 114,626,411 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	114,442,379 - 114,625,171 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	25,660,666 - 25,847,582 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Deptor
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624763	17,935,108 - 17,956,909 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624763	17,935,171 - 17,956,858 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Deptor
1196 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	141
Count of miRNA genes:	103
Interacting mature miRNAs:	113
Transcripts:	ENSRNOT00000005722, ENSRNOT00000064270
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
2293667	Bss42	Bone structure and strength QTL 42	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	7	47651439	92651439	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	43228750	88228750	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	80221299	124373579	Rat
2317035	Aia16	Adjuvant induced arthritis QTL 16	2.71		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	59238038	104238038	Rat
2298475	Eau6	Experimental allergic uveoretinitis QTL 6		0.0029	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	7	84257275	129257275	Rat
71114	Niddm14	Non-insulin dependent diabetes mellitus QTL 14	4.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	84257275	129257275	Rat
2293678	Bss24	Bone structure and strength QTL 24	6.71	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	7	47651439	92651439	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	43747012	108555253	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	69736356	112729554	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	73829340	130221005	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
2293685	Bmd21	Bone mineral density QTL 21	4.2	0.0003	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	7	47651439	92651439	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	83153392	128153392	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
634326	Hc3	Hypercalciuria QTL 3	2.1		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	7	42787314	87787314	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	81737938	126737938	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	80221299	109401111	Rat
2293696	Bmd32	Bone mineral density QTL 32	5.1	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	7	47651439	92651439	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	53612714	103945643	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	62004452	101773158	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	46590070	91590070	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	43747099	102228765	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
2293707	Bss32	Bone structure and strength QTL 32	7.64	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	47651439	92651439	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	80221299	125221299	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
1641908	Teswt1	Testicular weight QTL 1	3.28		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	7	80221299	94811326	Rat
2293644	Bmd29	Bone mineral density QTL 29	5.4	0.0001	femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	7	47651439	92651439	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	68938720	113886318	Rat
2300178	Bmd54	Bone mineral density QTL 54	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	7	47651439	92651439	Rat
724537	Niddm52	Non-insulin dependent diabetes mellitus QTL 52		0.02	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	80221299	93595843	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	61074194	106074194	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	44867533	89867533	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	80221299	112308525	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	62004452	101773158	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	68938720	113886318	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	68938720	113886318	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	69736226	117455174	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat

Markers in Region

D15Mit183

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	86,591,855 - 86,592,031 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	94,923,611 - 94,923,786	NCBI	Rnor6.0
Rnor_5.0	7	95,548,730 - 95,548,905	UniSTS	Rnor5.0
RGSC_v3.4	7	91,670,316 - 91,670,491	UniSTS	RGSC3.4
Cytogenetic Map	7	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001427213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001066889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008776470	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263557	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000005722 ⟹ ENSRNOP00000005722

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	86,514,988 - 86,663,778 (+)	Ensembl
Rnor_6.0 Ensembl	7	94,795,214 - 94,995,809 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095532 ⟹ ENSRNOP00000093077

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	86,514,992 - 86,667,773 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105476 ⟹ ENSRNOP00000097828

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	86,561,637 - 86,663,778 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119008 ⟹ ENSRNOP00000080538

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	86,514,988 - 86,666,888 (+)	Ensembl

RefSeq Acc Id:

NM_001427213 ⟹ NP_001414142

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	88,404,745 - 88,558,561 (+)	NCBI

RefSeq Acc Id:

XM_017595234 ⟹ XP_017450723

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	88,404,767 - 88,558,561 (+)	NCBI
mRatBN7.2	7	86,514,859 - 86,668,817 (+)	NCBI
Rnor_6.0	7	94,795,161 - 95,000,750 (+)	NCBI

Sequence:

show sequence

TGGACTCGCCGACCTCTTCAGCTTACCCGCAGGGATTCCCTCACCAGCCAATCGCGTCTGAGCC
ACGGGACCGCCCGGAACAAAGATGGCCGGAGCGGCCTCGGTGAGGGCACACTGATCCAAACGCC
AGGCGCACCCGCCTCCAGGACAGCAAAGGCAGAGTGGCAACCGCGCGGTCAGGAGCATGGAGGA
GGGCAGCAGCGGCGGCAGTGGTGGCAGCGACAGTAACGCCGGCGGGAGTGGCGGGGCACAGCAG
AGAGAGCTGGAACGCATGGCTGAAGTCCTAGTTACGGGAGAGCAGCTCCGACTGATGAGCCCTG
AAACTACACTCCTCCAGCCTAGGGAAGAGGAGGGGGTGAAGTATGAGCGAACCTTCATGGCATC
TGAATTCCTGGACTGGCTGGTTCAGGAAGGAGAAGCCACAACGAGGAAAGAGGCAGAGCAGCTT
TGCCACCGGCTCATGGAGCACAGCATCATACAGCATGTGTCTAACAAGCACCCATTTGTGGACA
GCAACCTCCTCTACCAGTTCAGAATGAACTTCCGTCGGAGGCGAAGACTGATGGAGCTGCTCAA
TGAGAAGTCCCCGTCCTCTCAGGAGACACATGACAGTCCCTTCTGTCTGAGGAAGCAGAGCCAC
GACAATCGGAAATCTACCAGCTTTATGTCAGTCAGCCCCAGCAAGGAGATCAAGATTGTGTCTG
CCGTGCGGAGGAGCAGCATGAGCAGCTGTGGCAGCAGTGGCTACTTCAGCAGCAGCCCGACGCT
CAGCAGCAGCCCCCCTGTGCTCTGCAACCCCAAATCTGTGCTGAAGAGACCTGTCACTTCTGAA
GAACTCTTGACCCCCGGGGCTCCATATGCAAGGAAGACATTCACGATTGTTGGTGACGCAGTTG
GCTGGGGCTTTGTGGTTCGAGGAAGTAAACCATGCCACATCCAGGCTGTGGACCCCAGCGGACC
TGCAGCTGCTGCAGGGATGAAGGTCTGTCAGTTTGTCGTCTCGGTGAATGGCCTCAACGTGCTG
AATGTAGACTACCGCACCGTGAGCAACCTGATTCTGACAGGCCCGAGGACAATTGTCATGGAAG
TCATGGAGGAGTTAGAATGCTGAGCAAGAAGACATCCCCGCTTGTACCCTGTCCCAGAACAACA
CAACAGTGGCGGGGCAAGACTGTCAGGCAAATGGATAATTGGGATATTACAGATCTTTTTCTCT
GACTGTACGCACCTTGACTTTCATACGCTGTTTGAATGCGGAAGAACCGGGTAACATGTCTTTA
AAAACCAAAACACAGCAAGGCAAGGTGGCTCAAGTCTATAATCCCAGCATTCAGGAGGGCAAGG
CAGAAGTGCTGCAAGTTCAAGGCCAGCATCAGCTAACTGTGAATGCCTGTCTCAAAACCACACA
AGGGATTTTTCCACACAAGCGCATACACATCACATGCACACATGTATGCACACGTGCACACACA
CCACACCACACCACACACATATACACCACACAGACGCACACGTGCACACACAGGCCAGTGTAGA
CAGCAGTGTAGGACAGTAGAGGACAATGGGGTGGAATTGCCTTATTAGAGCCCTAGTTTCTAGT
TCTCAGTCATTGCCTCTCATGTTTGCAGGAAGTTGTTGTAAAACCAACTTAGCAACATGGAAAA
ATGCCAGTTTTAGGAGTTCATAGAATAGTTACTACAGGGTTTGCATCATGTCTACTGTGTTTGT
GTGGCAAGAATAAGGAACGATCATCTGCTATCTGGGCTACTTAAGATACTGAGGCAGGAAGGTG
ATCACTTGAGCGCTGGTGGTGATGTCACCCTGGGCAACACAGTGACACCCCACATTAATTAAAA
AAAAATAGGTTTTACCAAAATTAGCCTGAGTCTGTTAGGTAGATCTAGATTTCACCTAGCTTAA
AATGAAAGCCGCATCCCCAGAAATGTGACCAGCTGACACCAATTTCCAAGAAGGTCCTTCCGCA
TTCAACAGCTTAGAAGCCATCATCATCACAAAGTAGCTTTCTTCCTCTCTCTTTTAAGCTTTGG
ATTTTTGTTGTTGTGTTGTGTCGTGTCTGCCTTTATCAGCCGCTTTCAGCTCAACCTGTTTCAG
TTGTGGCATGAGGTGAAAGATAAAAGAGACCACTGTGCCGTGGGTGGCAGGAATAGACAGGGGA
TGCCACCAGCAACCGCCTGCCTCTCTTTGCTTTCCCTGGGCCTGAGTGGTTTTGCCTTATGAGT
CAGCTCCAGCTGCTTTCTGGTGTTCATTTAGAACATACCGGTTGTGGAAGCAAAGAGTTCTGTC
CATACCGTGTAAGACTCAAAGTCAAGCCTCTGGCAAGACTGCACTTTAAGGGACTTGGCCTCAG
TGTGACAAAACTTGAAACTCCAAATGCCGTCTTAGCCTGGAGTTTTACAAGCCTTCTCGCGTCA
CGGGCTGTGCTGCTCCTTTAGGGACCTGCTTGGCACTGCAAAGCTCCACCTTGGTTTAGATTGC
TTCGTCTTAACTTATGCATGTTTCTTTGATCTAGAAGAGACTTCCTTTGAACCAGATATGGGAG
TGTGTTTCTGTAATCCCACCATGGAAGTGGAGGCAGAAAGATCATGTGTTCAAAAAAGACCTGA
GACAGGAGGCCCTGTGTCAAAACAAACATACAAACAACAAAAATGGTCAAGGGAGTGCATTTGG
GGTATTGGTATGTAGAGGATATTCCTCAAAGTGCCAAACAAGAGCCATTTTACCTAATGCATTT
TGAACAGAGAATCTACTTTCTTATTAGGCATTAACAAAATAATAGTATTATGCCTGGGTGATTT
CTTAATGAGATGCAGTCATCCGGTATTGGTGTTAGTGGAATGGATTTTATTAGTATATTAATCC
AACTTTTCTAACTTTAGTAAGAAAAGTGTAGGATTTTGAAGTGCCATGGGACAGCCGACATTGA
TGTTGTCAGTTGTTATTTGAGAGAGATTCTCTCCACGTCTGTTTATCCTGTGAGTGAGGCTCTG
TGCTGTAGCATTTATTGAGGATGTTCTCCCTCACTCCTCCACTTGCCCCTTTAAGTTAGACATT
GTTACCTTCATGTTTCAGGTAGGGAGACTAGGTCTGAGCAAATGCAATGTTCTTCAGGTTGAAG
CACATGCTGGAACTACCACGTACTATACAGCCCATTTCTCCAGTGCTCAAACCCCTTGCCTATC
TGCCCAGACTTCCTTTTCAGAGACCTTATGTTCAGTCTTTGCTCCAGGCTATGCTAAAACCTTA
TGGTTATTTTGTTGTTGCTCTTGTTTTATTGGCTGGAGAGGTCAGGACCATCATCATCCATTTT
ATAAATGATCAACCAATCATAAATCAGTTGGTTCATCACATGCTCAAAACACCCCAGGTACTAA
GCAGGAGGCCTTGCCACATGGCTTTAATTTCTGTCTGTTTTGTTTGTTGATTTGTTTTGAGACA
GGGTCAAGCTCTTGATCCTGCACTTGCTATGTGGGATCACAGGCACACAGACCCATACTCGGTA
TGATAACACCTTAGAAGATGAGTCTCGGTTGTTTTCTGTCTTTGGTATTCCTTGGCTGACAAGA
AAGCAAGAATGCCCATGGGGCATGATATCCTTCTTGCTGCTCACCTCCAAATGCCCTTTGCCTT
GAACCCTGAATCCTATCATTTCCCTGTGGCCAAACTCAACACCACAGGAGCCCCTCTCTGTCAG
GGAGGGAGGGACGAACAGTTCAGCTGTTTTCTTATTTGGTTCTTCTCATTCCCAGTTTAAAGTC
CAAGTGCTGGAGGGGGAAACTTTTTATAAGACAGGGTGTTGGTCATAGTGCATGCCTTTAATCG
CAGCACTCTGGAGGCAGAGTCAAGCACAGGTAGATCTCTATGAGTTTGAGGCCAGACTGGTCTA
CAGAGTGAGTTCCAGGACATCCAGGGCTACACAGAGAAACCCTATCTCAAAAGCACAAAAAGAA
AAGAAAAAAGAAAAAAATGTAGCATGGGCTGTGCTCAAACTAATACTCCTGCCTCAAGGAATTC
CTGTGGCTCAGAGACCGGACACTTTGACTTCCAATTAAAAAACTAGCACTGAGCTGGAGAGAGA
ACACAGTGATGAAGAGCTTGGCTTGTTCTTCCACGGGACCCAAGCTTGCTTCTTAGAACTACGT
AACAGCTCACGCCTAGCTATGGCTCTAATGACACAGGATCTGACACCCTCTGCTGACCTCCTTG
GGCACACATGGTGCCCAAACATAGGTACATGCAAACTATCCATATGCATACAATTAAAGTGAAT
AAATACTTTAAAAATACGTTAATAAATAAAACGAGCCCAGAATCCAGGAAGGGAGAAATAAACA
CCACCTTTTATGAGAAGACTTGCATAGAATTTGTGACCAATTTGAAGTCTCTAAAAATAAATTC
AGAGAAGGAGCCATTATTAGTTGAATGCAGTTATTGAAGGCTGTAGACTCTCGAATCAGATTCT
TACCCAGCCACTAGATGAGAGTGAGGTGGACCTGCAGGCTGGTTTATAATGAAACCCTCAGAGC
CCATGGGTCCTAAAATGTCAGTGGGGCGTGGGCCGGGTAGAACACAGTTTAATCATTTCATTTG
ATTAATGAATGAGGCATAAAACAATCTTGGGCTATTCCCAGACTTGTGAGGCTTGGCTGAATCC
CTTCTGAGTCTCCTGCCTTGCATCCCTGTTGCAGTAGATTCTTCTGCAGCACAGAGTCATGCAG
CAGAAACGGGCCTATGGCAAGATGTACTCAAAACAAAAGTGACACCAGGTATCTCTGAAGAGAA
GGGAGAATCATCTGCTATTGTCATTTGTTTTAAATACCACGGTCTTATTCTGTATGTGTTCCAT
GTTGTCCAGGAACTTACAGTATGGCACAGGCTAGTCTTAAATTCACAGAAATCTTCCTGCTTCA
GCCTCCTGAGGACTTGAATGAGAGGACCAAGCTACCATGCCTGGTTAAATGGAGTTTGGTCTTT
ATGTGGATTTGTATGTCTGTGATCTTCAGGGAGGAAACAATGATTACTTATTCACTGCCTGAGA
TAACATTTACCTGCACACCTTGGACACATTCCTTCTTGTTCCCTTAGAAAATATATTTTCGAGT
CCAACGCCTTAACCACTCGGCCATCACAGCCGCAGAAAATATATTTTCAAAACCAGGCGTGATC
GCTCACACCTATGATCCCAGCATTCAGGAAGCAGAGGCTAGCCTAGGCTACAGAGACTTTGTCT
CAAAAACAAAACTAGACAAGAAATTCTAGACTTTTTTTTTTAGATGTTTGTTTGTGGTGTTTAT
GTTTTGATGATAGAAAGACAGTCTTTTTTGTTTCTTTGTTAGCACAGTATGTAAATTAGAAGGA
CCTCTTTTATTAAAATGAAAACTGCATTATCTCTTTGGCTGTTTCTGCCTTCTGAAGTTTAATT
ACGAATGGGTGGGATGGCCCACAGCACGAAGATGCATGCTGGAAAATGGAATTTGAGTCCACAC
ACAGAGACCCTGTCTAAAAACTAATTTGTTAGGTCTAAAATCTCACACTTCTAATCCCAGCACT
GCAGAGGCAGAAGGATCACCCCATCTAAGGCTAGCCTGGGCTACATGTGATACCCAAAAGACAT
AAGAATTAGGGAGACTAGTTGAGAAGGTAGAGTGAGGAAGATGAGCCATCTTTGCATAGATGAG
GTGTGGCTGACTTCACACTATCACGTGACAGGTGTCTCTGCTTTGGAAGGACAGACACCAAGAT
CAAGAACATCGCTGCTTTCTATTCAAATTGGATTCTTGAGTTTCCAAATCTTCTTTCCTATCAA
ACATATTGTGGAGATCGTCAACTTTCAGGGCCTATTTTAAACCCTTGGTACTGGCTCTGGCTGC
TAAGAATTCTGTTTTACTTTGACTAGAAATGATCAGAATAACTCCAGAGCACTGCGGTGTTTCT
GACTGGCTGAAATTGATGATTGACGTTAATCATGATTTCCTGTCACCTGAACTGCAGGTGAGAT
GTATATTTCTTCACTGCAGTACCAAAAGGACAAATGAGCCGTATGCCAAAATGAAGTTCGCCAT
CAAAAATCGCATATGTACTGTTAAACAAGCTTAAACGTACTTAATATATAGCTTTATTTTGAAA
TTTGGTGAGAGTGATTTGCTATCTTTAATAAAGCTGTACCATAAGACTTAGGATGATTGTATGA
AAATACAAGAGCATGAAATAAATGTTACATTTTTTAAAGTTA

hide sequence

RefSeq Acc Id:

XM_063263556 ⟹ XP_063119626

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	88,404,767 - 88,574,065 (+)	NCBI

RefSeq Acc Id:

XM_063263557 ⟹ XP_063119627

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	88,404,767 - 88,574,065 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001414142	(Get FASTA)	NCBI Sequence Viewer
	XP_017450723	(Get FASTA)	NCBI Sequence Viewer
	XP_063119626	(Get FASTA)	NCBI Sequence Viewer
	XP_063119627	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM16252	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005722.6
	ENSRNOP00000080538.1
	ENSRNOP00000093077.1
	ENSRNOP00000097828.1

RefSeq Acc Id:

XP_017450723 ⟸ XM_017595234

- Peptide Label:

isoform X3

- Sequence:

show sequence

MEEGSSGGSGGSDSNAGGSGGAQQRELERMAEVLVTGEQLRLMSPETTLLQPREEEGVKYERTF
MASEFLDWLVQEGEATTRKEAEQLCHRLMEHSIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLME
LLNEKSPSSQETHDSPFCLRKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSS
PTLSSSPPVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDP
SGPAAAAGMKVCQFVVSVNGLNVLNVDYRTVSNLILTGPRTIVMEVMEELEC

hide sequence

Ensembl Acc Id:

ENSRNOP00000005722 ⟸ ENSRNOT00000005722

Ensembl Acc Id:

ENSRNOP00000097828 ⟸ ENSRNOT00000105476

Ensembl Acc Id:

ENSRNOP00000093077 ⟸ ENSRNOT00000095532

Ensembl Acc Id:

ENSRNOP00000080538 ⟸ ENSRNOT00000119008

RefSeq Acc Id:	NP_001414142 ⟸ NM_001427213
- UniProtKB:	A0A8I5ZQX9 (UniProtKB/TrEMBL), A6HRG9 (UniProtKB/TrEMBL), F1M8Y4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119626 ⟸ XM_063263556
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AIZ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119627 ⟸ XM_063263557
- Peptide Label:	isoform X2

Protein Domains

DEP PDZ

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M8Y4-F1-model_v2	AlphaFold	F1M8Y4	1-409	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695355

Promoter ID:

EPDNEW_R5860

Type:

multiple initiation site

Name:

Deptor_1

Description:

DEP domain containing MTOR-interacting protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	94,795,310 - 94,795,370	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561030	AgrOrtholog
BioCyc Gene	G2FUF-33380	BioCyc
Ensembl Genes	ENSRNOG00000004328	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005722.9	UniProtKB/TrEMBL
	ENSRNOT00000095532.1	UniProtKB/TrEMBL
	ENSRNOT00000105476.1	UniProtKB/TrEMBL
	ENSRNOT00000119008.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	2.30.42.10	UniProtKB/TrEMBL
InterPro	DEP_dom	UniProtKB/TrEMBL
	DEPTOR_DEP_1	UniProtKB/TrEMBL
	DEPTOR_DEP_2	UniProtKB/TrEMBL
	mTOR-Rac_regulators	UniProtKB/TrEMBL
	PDZ/DHR/GLGF	UniProtKB/TrEMBL
	PDZ_sf	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	314979	ENTREZGENE
PANTHER	DEP DOMAIN PROTEIN	UniProtKB/TrEMBL
	PTHR22829:SF18	UniProtKB/TrEMBL
Pfam	DEP	UniProtKB/TrEMBL
PhenoGen	Deptor	PhenoGen
PROSITE	DEP	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004328	RatGTEx
SMART	DEP	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
Superfamily-SCOP	PDZ	UniProtKB/TrEMBL
	SSF46785	UniProtKB/TrEMBL
UniProt	A0A8I5ZQX9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AIZ7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6B6C9_RAT	UniProtKB/TrEMBL
	A6HRG9	ENTREZGENE, UniProtKB/TrEMBL
	F1M8Y4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-29	Deptor	DEP domain containing MTOR-interacting protein	LOC102547145	uncharacterized LOC102547145	Data merged from RGD:7615485	737654	PROVISIONAL
2015-07-29	Deptor	DEP domain containing MTOR-interacting protein	LOC100359815	hypothetical protein LOC100359815	Data merged from RGD:2323326	737654	PROVISIONAL
2013-12-18	LOC102547145	uncharacterized LOC102547145			Symbol and Name status set to provisional	70820	PROVISIONAL
2011-08-02	Deptor	DEP domain containing MTOR-interacting protein	Depdc6	DEP domain containing 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-06	LOC100359815	hypothetical protein LOC100359815			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-09-16	Depdc6	DEP domain containing 6	RGD1561030	similar to DEP domain containing 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1561030	similar to DEP domain containing 6	RGD1561030_predicted	similar to DEP domain containing 6 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1561030_predicted	similar to DEP domain containing 6 (predicted)	LOC314979	similar to DEP domain containing 6	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC314979	similar to DEP domain containing 6			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)