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Gene: Zhx2 (zinc fingers and homeoboxes 2) Rattus norvegicus
Symbol: Zhx2
Name: zinc fingers and homeoboxes 2
RGD ID: 727926
Description: Predicted to have DNA-binding transcription factor activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in generation of neurons; negative regulation of gene expression; and somatic stem cell population maintenance. Predicted to localize to cytosol and nucleoplasm. Orthologous to human ZHX2 (zinc fingers and homeoboxes 2); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AFP regulator 1; alpha-fetoprotein regulator 1; regulator of AFP; transcription factor ZHX2; zinc finger and homeodomain protein 2; zinc fingers and homeoboxes protein 2
Homo sapiens (human) : ZHX2 (zinc fingers and homeoboxes 2)  HGNC  Alliance
Mus musculus (house mouse) : Zhx2 (zinc fingers and homeoboxes 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zhx2 (zinc fingers and homeoboxes 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZHX2 (zinc fingers and homeoboxes 2)
Canis lupus familiaris (dog) : ZHX2 (zinc fingers and homeoboxes 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zhx2 (zinc fingers and homeoboxes 2)
Sus scrofa (pig) : ZHX2 (zinc fingers and homeoboxes 2)
Chlorocebus sabaeus (African green monkey) : ZHX2 (zinc fingers and homeoboxes 2)
Heterocephalus glaber (naked mole-rat) : Zhx2 (zinc fingers and homeoboxes 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0797,559,653 - 97,707,872 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl797,559,841 - 97,695,739 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0798,166,854 - 98,314,735 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4794,528,435 - 94,530,945 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1794,563,246 - 94,563,739 (+)NCBI
Celera786,000,415 - 86,135,018 (+)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Zhx2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 727926
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.