Zhx2 (zinc fingers and homeoboxes 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Zhx2 (zinc fingers and homeoboxes 2) Rattus norvegicus
Analyze
Symbol: Zhx2
Name: zinc fingers and homeoboxes 2
RGD ID: 727926
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and retinal bipolar neuron differentiation. Predicted to act upstream of or within mRNA catabolic process; negative regulation of neuron differentiation; and somatic stem cell population maintenance. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZHX2 (zinc fingers and homeoboxes 2); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AFP regulator 1; alpha-fetoprotein regulator 1; regulator of AFP; transcription factor ZHX2; zinc finger and homeodomain protein 2; zinc fingers and homeoboxes protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8791,115,894 - 91,263,823 (+)NCBIGRCr8
mRatBN7.2789,226,358 - 89,374,266 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl789,226,463 - 89,374,378 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx791,104,191 - 91,239,446 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0793,305,463 - 93,440,722 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0793,117,212 - 93,252,387 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0797,559,653 - 97,707,872 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl797,559,841 - 97,695,739 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0798,166,854 - 98,314,735 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4794,528,435 - 94,530,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1794,563,246 - 94,563,739 (+)NCBI
Celera786,000,415 - 86,135,018 (+)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
GSK-J4  (ISO)
L-methionine  (ISO)
manganese(II) chloride  (EXP)
methimazole  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
Monobutylphthalate  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor. Kawata H, etal., Biochem J 2003 Aug 1;373(Pt 3):747-57.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1370712   PMID:7523852   PMID:10673330   PMID:17056598   PMID:17457373   PMID:19515908   PMID:30146259  


Genomics

Comparative Map Data
Zhx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8791,115,894 - 91,263,823 (+)NCBIGRCr8
mRatBN7.2789,226,358 - 89,374,266 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl789,226,463 - 89,374,378 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx791,104,191 - 91,239,446 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0793,305,463 - 93,440,722 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0793,117,212 - 93,252,387 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0797,559,653 - 97,707,872 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl797,559,841 - 97,695,739 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0798,166,854 - 98,314,735 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4794,528,435 - 94,530,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1794,563,246 - 94,563,739 (+)NCBI
Celera786,000,415 - 86,135,018 (+)NCBICelera
Cytogenetic Map7q33NCBI
ZHX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388122,780,379 - 122,974,510 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8122,781,655 - 122,974,510 (+)EnsemblGRCh38hg38GRCh38
GRCh378123,792,618 - 123,986,750 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368123,863,082 - 124,055,936 (+)NCBINCBI36Build 36hg18NCBI36
Build 348123,863,169 - 124,055,929NCBI
Celera8119,982,978 - 120,175,825 (+)NCBICelera
Cytogenetic Map8q24.13NCBI
HuRef8119,119,533 - 119,312,420 (+)NCBIHuRef
CHM1_18123,834,160 - 124,026,965 (+)NCBICHM1_1
T2T-CHM13v2.08123,911,550 - 124,105,660 (+)NCBIT2T-CHM13v2.0
Zhx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391557,558,063 - 57,703,228 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1557,558,061 - 57,703,228 (+)EnsemblGRCm39 Ensembl
GRCm381557,694,667 - 57,839,832 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1557,694,665 - 57,839,832 (+)EnsemblGRCm38mm10GRCm38
MGSCv371557,526,222 - 57,671,387 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361557,524,854 - 57,669,854 (+)NCBIMGSCv36mm8
Celera1559,214,205 - 59,360,402 (+)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1524.01NCBI
Zhx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555401,805,666 - 1,890,409 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555401,805,648 - 1,890,409 (+)NCBIChiLan1.0ChiLan1.0
ZHX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27140,210,065 - 140,403,883 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18115,722,800 - 115,916,584 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08119,473,607 - 119,668,790 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18122,306,315 - 122,424,518 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8122,401,567 - 122,404,080 (+)Ensemblpanpan1.1panPan2
ZHX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11321,231,985 - 21,393,756 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1321,377,316 - 21,379,832 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1321,342,934 - 21,359,598 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01321,568,837 - 21,730,547 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1321,569,100 - 21,730,552 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11321,297,771 - 21,459,250 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01321,402,546 - 21,564,353 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01321,645,278 - 21,807,009 (+)NCBIUU_Cfam_GSD_1.0
Zhx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530316,889,272 - 17,048,441 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647024,315,404 - 24,474,282 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647024,315,371 - 24,476,063 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZHX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl416,374,902 - 16,553,002 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1416,374,900 - 16,553,859 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2417,144,095 - 17,315,274 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZHX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18117,360,134 - 117,550,818 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8117,531,654 - 117,534,167 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603922,683,909 - 22,875,372 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zhx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473531,882,434 - 32,013,773 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zhx2
630 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:26
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000007326
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1641908Teswt1Testicular weight QTL 13.28testis mass (VT:1000644)both testes wet weight (CMO:0000175)78022129994811326Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
724537Niddm52Non-insulin dependent diabetes mellitus QTL 520.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)78022129993595843Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
RH139926  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2789,365,177 - 89,365,371 (+)MAPPERmRatBN7.2
Rnor_6.0797,698,751 - 97,698,944NCBIRnor6.0
Rnor_5.0798,305,609 - 98,305,802UniSTSRnor5.0
RGSC_v3.4794,533,957 - 94,534,150UniSTSRGSC3.4
Celera786,138,029 - 86,138,222UniSTS
RH 3.4 Map7607.5UniSTS
Cytogenetic Map7q32UniSTS
BF397441  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2789,369,983 - 89,370,138 (+)MAPPERmRatBN7.2
Rnor_6.0797,703,557 - 97,703,711NCBIRnor6.0
Rnor_5.0798,310,415 - 98,310,569UniSTSRnor5.0
RGSC_v3.4794,538,763 - 94,538,917UniSTSRGSC3.4
Celera786,142,835 - 86,142,989UniSTS
RH 3.4 Map7609.6UniSTS
Cytogenetic Map7q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000007326   ⟹   ENSRNOP00000007326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl789,231,977 - 89,374,378 (+)Ensembl
Rnor_6.0 Ensembl797,559,841 - 97,695,739 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095346   ⟹   ENSRNOP00000077300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl789,252,590 - 89,374,378 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099915   ⟹   ENSRNOP00000095233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl789,226,963 - 89,364,681 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107215   ⟹   ENSRNOP00000092484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl789,226,463 - 89,374,378 (+)Ensembl
RefSeq Acc Id: NM_001271056   ⟹   NP_001257985
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8791,116,487 - 91,251,723 (+)NCBI
mRatBN7.2789,226,928 - 89,362,166 (+)NCBI
Rnor_6.0797,559,841 - 97,695,739 (+)NCBI
Rnor_5.0798,166,854 - 98,314,735 (+)NCBI
Celera786,000,415 - 86,135,018 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241654   ⟹   XP_006241716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8791,115,894 - 91,263,823 (+)NCBI
mRatBN7.2789,226,358 - 89,374,266 (+)NCBI
Rnor_6.0797,559,653 - 97,707,872 (+)NCBI
Rnor_5.0798,166,854 - 98,314,735 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594857   ⟹   XP_017450346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8791,169,243 - 91,263,823 (+)NCBI
mRatBN7.2789,279,678 - 89,374,266 (+)NCBI
Rnor_6.0797,612,982 - 97,707,872 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063263558   ⟹   XP_063119628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8791,186,265 - 91,263,823 (+)NCBI
RefSeq Acc Id: NP_001257985   ⟸   NM_001271056
- UniProtKB: Q80VX4 (UniProtKB/Swiss-Prot),   G3V6P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241716   ⟸   XM_006241654
- Peptide Label: isoform X1
- UniProtKB: Q80VX4 (UniProtKB/Swiss-Prot),   G3V6P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450346   ⟸   XM_017594857
- Peptide Label: isoform X1
- UniProtKB: Q80VX4 (UniProtKB/Swiss-Prot),   G3V6P3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007326   ⟸   ENSRNOT00000007326
Ensembl Acc Id: ENSRNOP00000095233   ⟸   ENSRNOT00000099915
Ensembl Acc Id: ENSRNOP00000092484   ⟸   ENSRNOT00000107215
Ensembl Acc Id: ENSRNOP00000077300   ⟸   ENSRNOT00000095346
RefSeq Acc Id: XP_063119628   ⟸   XM_063263558
- Peptide Label: isoform X1
- UniProtKB: Q80VX4 (UniProtKB/Swiss-Prot),   G3V6P3 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80VX4-F1-model_v2 AlphaFold Q80VX4 1-836 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727926 AgrOrtholog
BioCyc Gene G2FUF-33346 BioCyc
Ensembl Genes ENSRNOG00000005417 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007326.6 UniProtKB/Swiss-Prot
  ENSRNOT00000095346.1 UniProtKB/Swiss-Prot
  ENSRNOT00000099915.1 UniProtKB/Swiss-Prot
  ENSRNOT00000107215.1 UniProtKB/Swiss-Prot
  ENSRNOT00000133696 ENTREZGENE
  ENSRNOT00000135055 ENTREZGENE
  ENSRNOT00000169837 ENTREZGENE
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot
InterPro Homeobox UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot
  ZHX_Znf_C2H2 UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report rno:314988 UniProtKB/Swiss-Prot
NCBI Gene 314988 ENTREZGENE
PANTHER ZINC FINGERS AND HOMEOBOXES PROTEIN 2 UniProtKB/Swiss-Prot
  ZINC-FINGERS AND HOMEOBOXES RELATED UniProtKB/Swiss-Prot
Pfam Homeodomain UniProtKB/Swiss-Prot
  zf_C2H2_ZHX UniProtKB/Swiss-Prot
PhenoGen Zhx2 PhenoGen
PROSITE HOMEOBOX_2 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005417 RatGTEx
SMART HOX UniProtKB/Swiss-Prot
  ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP Homeodomain_like UniProtKB/Swiss-Prot
  SSF57667 UniProtKB/Swiss-Prot
UniProt G3V6P3 ENTREZGENE
  Q80VX4 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary G3V6P3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Zhx2  zinc fingers and homeoboxes 2    transcription factor ZHX2  Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function human homolog functions as a transcriptional repressor 1299601