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Gene: Myc (MYC proto-oncogene, bHLH transcription factor) Rattus norvegicus
Symbol: Myc
Name: MYC proto-oncogene, bHLH transcription factor
Description: Exhibits DNA binding activity; DNA-binding transcription factor activity; and transcription factor binding activity. Involved in several processes, including cellular response to lipid; cellular response to organonitrogen compound; and positive regulation of cellular metabolic process. Localizes to cytoplasm and nucleolus. Used to study artery disease (multiple); hepatocellular carcinoma; leiomyoma; osteoporosis; and prostatic hypertrophy. Biomarker of breast cancer; carcinoma (multiple); obesity; polycystic kidney disease; and prolactinoma. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); demyelinating disease; hematologic cancer (multiple); prostate cancer (multiple); and urinary bladder cancer. Orthologous to human MYC (MYC proto-oncogene, bHLH transcription factor); PARTICIPATES IN ceramide signaling pathway; interleukin-2 signaling pathway; interleukin-6 signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-schisandrin B; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Avian myelocytomatosis viral (v-myc) oncogene homolog; c-myc; MGC105490; mMyc; myc proto-oncogene protein; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; myelocytomatosis viral oncogene homolog (avian); proto-oncogene c-Myc; RNCMYC; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog
Homo sapiens (human) : MYC (MYC proto-oncogene, bHLH transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Myc (myelocytomatosis oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myc (MYC proto-oncogene, bHLH transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MYC (MYC proto-oncogene, bHLH transcription factor)
Canis lupus familiaris (dog) : MYC (MYC proto-oncogene, bHLH transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myc (MYC proto-oncogene, bHLH transcription factor)
Sus scrofa (pig) : MYC (MYC proto-oncogene, bHLH transcription factor)
Chlorocebus sabaeus (African green monkey) : MYC (MYC proto-oncogene, bHLH transcription factor)
Heterocephalus glaber (naked mole-rat) : Myc (MYC proto-oncogene, bHLH transcription factor)
more info ...
Is Marker For: Strains:   W-Tg(MT2A-Myc)1Ys   W-Tg(MT2A-Myc)2Ys  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07102,586,313 - 102,591,240 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7102,586,313 - 102,591,240 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07103,157,452 - 103,162,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4798,953,142 - 98,958,060 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1798,987,371 - 98,992,287 (+)NCBI
Celera790,263,903 - 90,268,823 (+)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers