Slc30a8 (solute carrier family 30 member 8) - Rat Genome Database

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Gene: Slc30a8 (solute carrier family 30 member 8) Rattus norvegicus
Analyze
Symbol: Slc30a8
Name: solute carrier family 30 member 8
RGD ID: 1308282
Description: Enables zinc ion transmembrane transporter activity. Involved in several processes, including insulin secretion; positive regulation of insulin secretion; and zinc ion import across plasma membrane. Predicted to be located in secretory granule membrane. Predicted to be active in plasma membrane and secretory granule. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC30A8 (solute carrier family 30 member 8); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; aldehydo-D-glucose; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC299903; proton-coupled zinc antiporter SLC30A8; solute carrier family 30 (zinc transporter), member 8; zinc transporter 8; ZnT-8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Slc30a8em1Mcwi   Slc30a8em2Mcwi  
Genetic Models: SS-Slc30a8em1Mcwi SS-Slc30a8em2Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2783,591,993 - 83,627,786 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl783,591,993 - 83,626,305 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx785,509,786 - 85,542,609 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0787,710,991 - 87,743,815 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0787,515,694 - 87,548,480 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0791,832,988 - 91,869,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl791,832,988 - 91,867,300 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0792,476,024 - 92,512,365 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4788,583,770 - 88,617,145 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1788,604,575 - 88,639,923 (+)NCBI
Celera780,455,350 - 80,488,134 (+)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis? Egefjord L, etal., BMC Endocr Disord. 2009 Feb 25;9(1):7.
2. Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion. Fu Y, etal., PLoS One. 2009 May 25;4(5):e5679.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands. Murgia C, etal., Nutr Metab Cardiovasc Dis. 2009 Jul;19(6):431-9. Epub 2008 Dec 17.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:15331542   PMID:16984975   PMID:19450229   PMID:19706465   PMID:21208276   PMID:23209723   PMID:26281917   PMID:26720469  


Genomics

Comparative Map Data
Slc30a8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2783,591,993 - 83,627,786 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl783,591,993 - 83,626,305 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx785,509,786 - 85,542,609 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0787,710,991 - 87,743,815 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0787,515,694 - 87,548,480 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0791,832,988 - 91,869,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl791,832,988 - 91,867,300 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0792,476,024 - 92,512,365 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4788,583,770 - 88,617,145 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1788,604,575 - 88,639,923 (+)NCBI
Celera780,455,350 - 80,488,134 (+)NCBICelera
Cytogenetic Map7q31NCBI
SLC30A8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388116,950,217 - 117,176,714 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8116,950,273 - 117,176,714 (+)EnsemblGRCh38hg38GRCh38
GRCh378117,962,456 - 118,188,953 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368118,216,518 - 118,258,134 (+)NCBINCBI36Build 36hg18NCBI36
Build 348118,216,747 - 118,254,101NCBI
Celera8114,151,202 - 114,377,691 (+)NCBICelera
Cytogenetic Map8q24.11NCBI
HuRef8113,288,921 - 113,515,635 (+)NCBIHuRef
CHM1_18118,002,722 - 118,228,963 (+)NCBICHM1_1
T2T-CHM13v2.08118,078,388 - 118,305,142 (+)NCBIT2T-CHM13v2.0
Slc30a8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391552,158,949 - 52,199,194 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1552,158,949 - 52,199,194 (+)EnsemblGRCm39 Ensembl
GRCm381552,295,553 - 52,335,798 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1552,295,553 - 52,335,798 (+)EnsemblGRCm38mm10GRCm38
MGSCv371552,127,108 - 52,167,288 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361552,125,636 - 52,165,816 (+)NCBIMGSCv36mm8
Celera1553,863,656 - 53,904,335 (+)NCBICelera
Cytogenetic Map15CNCBI
cM Map1519.88NCBI
Slc30a8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541723,207,146 - 23,236,874 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541723,207,146 - 23,239,170 (+)NCBIChiLan1.0ChiLan1.0
SLC30A8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan18109,872,083 - 110,098,929 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08113,624,785 - 113,851,633 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18116,167,700 - 116,394,095 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8116,223,595 - 116,394,095 (+)Ensemblpanpan1.1panPan2
SLC30A8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11316,602,255 - 16,637,299 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1316,601,912 - 16,635,880 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1316,603,610 - 16,638,559 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01316,898,497 - 16,933,443 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1316,898,295 - 16,932,026 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11316,635,055 - 16,670,008 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01316,734,977 - 16,770,163 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01316,978,714 - 17,013,658 (+)NCBIUU_Cfam_GSD_1.0
Slc30a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530321,687,819 - 21,725,947 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647029,114,713 - 29,151,993 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647029,114,713 - 29,151,993 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC30A8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl421,517,486 - 21,555,746 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1421,517,009 - 21,557,747 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2422,786,105 - 22,824,455 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC30A8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18111,588,517 - 111,819,908 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8111,769,181 - 111,815,885 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603928,509,132 - 28,557,839 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc30a8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476315,431,806 - 15,461,833 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476315,393,221 - 15,469,819 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc30a8
66 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:92
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000006410
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
724537Niddm52Non-insulin dependent diabetes mellitus QTL 520.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)78022129993595843Rat
1641908Teswt1Testicular weight QTL 13.28testis mass (VT:1000644)both testes wet weight (CMO:0000175)78022129994811326Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
D7Rat141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2783,591,953 - 83,592,070 (+)MAPPERmRatBN7.2
Rnor_6.0791,832,949 - 91,833,065NCBIRnor6.0
Rnor_5.0792,475,985 - 92,476,101UniSTSRnor5.0
RGSC_v3.4788,583,730 - 88,583,847RGDRGSC3.4
RGSC_v3.4788,583,731 - 88,583,847UniSTSRGSC3.4
RGSC_v3.1788,604,461 - 88,604,577RGD
Celera780,455,311 - 80,455,427UniSTS
RH 3.4 Map7573.4RGD
RH 3.4 Map7573.4UniSTS
RH 2.0 Map7490.3RGD
SHRSP x BN Map750.08RGD
Cytogenetic Map7q31UniSTS


Genetic Models
This gene Slc30a8 is modified in the following models/strains:


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 1 4 6 5 2 5 2 8
Below cutoff 2 27 35 20 14 20 4 6 42 9 32 10 4

Sequence


RefSeq Acc Id: ENSRNOT00000006410   ⟹   ENSRNOP00000006410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl783,591,993 - 83,626,305 (+)Ensembl
Rnor_6.0 Ensembl791,832,988 - 91,865,774 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079792   ⟹   ENSRNOP00000069455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl791,833,297 - 91,867,300 (+)Ensembl
RefSeq Acc Id: NM_001130538   ⟹   NP_001124010
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2783,591,993 - 83,624,779 (+)NCBI
Rnor_6.0791,832,988 - 91,865,774 (+)NCBI
Rnor_5.0792,476,024 - 92,512,365 (+)NCBI
RGSC_v3.4788,583,770 - 88,617,145 (+)RGD
Celera780,455,350 - 80,488,134 (+)RGD
Sequence:
RefSeq Acc Id: XM_006241645   ⟹   XP_006241707
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2783,591,993 - 83,627,786 (+)NCBI
Rnor_6.0791,832,988 - 91,869,329 (+)NCBI
Rnor_5.0792,476,024 - 92,512,365 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008765500   ⟹   XP_008763722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2783,592,302 - 83,627,786 (+)NCBI
Rnor_6.0791,833,225 - 91,869,329 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001124010 (Get FASTA)   NCBI Sequence Viewer  
  XP_006241707 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763722 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM16273 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006410
  ENSRNOP00000006410.7
  ENSRNOP00055030199
  ENSRNOP00060003825
  ENSRNOP00065019265
GenBank Protein P0CE46 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001124010   ⟸   NM_001130538
- UniProtKB: P0CE46 (UniProtKB/Swiss-Prot),   A0A0H2UHD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241707   ⟸   XM_006241645
- Peptide Label: isoform X1
- UniProtKB: P0CE46 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008763722   ⟸   XM_008765500
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000006410   ⟸   ENSRNOT00000006410
RefSeq Acc Id: ENSRNOP00000069455   ⟸   ENSRNOT00000079792

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0CE46-F1-model_v2 AlphaFold P0CE46 1-368 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308282 AgrOrtholog
BioCyc Gene G2FUF-33421 BioCyc
Ensembl Genes ENSRNOG00000004747 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055021677 UniProtKB/Swiss-Prot
  ENSRNOG00060003155 UniProtKB/Swiss-Prot
  ENSRNOG00065014921 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000006410 ENTREZGENE
  ENSRNOT00000006410.7 UniProtKB/Swiss-Prot
  ENSRNOT00055037112 UniProtKB/Swiss-Prot
  ENSRNOT00060005189 UniProtKB/Swiss-Prot
  ENSRNOT00065024677 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1510.10 UniProtKB/Swiss-Prot
InterPro Cation_efflux UniProtKB/Swiss-Prot
  Cation_efflux_CTD_sf UniProtKB/Swiss-Prot
  Cation_efflux_TMD_sf UniProtKB/Swiss-Prot
KEGG Report rno:299903 UniProtKB/Swiss-Prot
NCBI Gene 299903 ENTREZGENE
PANTHER CATION EFFLUX PROTEIN/ ZINC TRANSPORTER UniProtKB/Swiss-Prot
  PTHR11562:SF37 UniProtKB/Swiss-Prot
Pfam Cation_efflux UniProtKB/Swiss-Prot
PhenoGen Slc30a8 PhenoGen
RatGTEx ENSRNOG00000004747 RatGTEx
  ENSRNOG00055021677 RatGTEx
  ENSRNOG00060003155 RatGTEx
  ENSRNOG00065014921 RatGTEx
Superfamily-SCOP SSF160240 UniProtKB/Swiss-Prot
  SSF161111 UniProtKB/Swiss-Prot
UniProt A0A0H2UHD4 ENTREZGENE
  P0CE46 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Slc30a8  solute carrier family 30 (zinc transporter), member 8   Slc30a8_predicted  solute carrier family 30 (zinc transporter), member 8 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Slc30a8_predicted  solute carrier family 30 (zinc transporter), member 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED