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Gene: Slc30a8 (solute carrier family 30 member 8) Rattus norvegicus
Symbol: Slc30a8
Name: solute carrier family 30 member 8
RGD ID: 1308282
Description: Predicted to have protein homodimerization activity and zinc ion transmembrane transporter activity. Involved in several processes, including insulin secretion; ion homeostasis; and positive regulation of insulin secretion. Localizes to cytoplasmic vesicle. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC30A8 (solute carrier family 30 member 8); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; aldehydo-D-glucose; bisphenol A.
Type: protein-coding
Also known as: LOC299903; solute carrier family 30 (zinc transporter), member 8; zinc transporter 8; ZnT-8
Homo sapiens (human) : SLC30A8 (solute carrier family 30 member 8)  HGNC  Alliance
Mus musculus (house mouse) : Slc30a8 (solute carrier family 30 (zinc transporter), member 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc30a8 (solute carrier family 30 member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC30A8 (solute carrier family 30 member 8)
Canis lupus familiaris (dog) : SLC30A8 (solute carrier family 30 member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc30a8 (solute carrier family 30 member 8)
Sus scrofa (pig) : SLC30A8 (solute carrier family 30 member 8)
Chlorocebus sabaeus (African green monkey) : SLC30A8 (solute carrier family 30 member 8)
Heterocephalus glaber (naked mole-rat) : Slc30a8 (solute carrier family 30 member 8)
more info ...
Allele / Splice: Slc30a8em1Mcwi   Slc30a8em2Mcwi  
Genetic Models: SS-Slc30a8em1Mcwi SS-Slc30a8em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0791,832,988 - 91,869,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl791,832,988 - 91,867,300 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0792,476,024 - 92,512,365 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4788,583,770 - 88,617,145 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1788,604,575 - 88,639,923 (+)NCBI
Celera780,455,350 - 80,488,134 (+)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Slc30a8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308282
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.