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Gene: Derl1 (derlin 1) Rattus norvegicus
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Symbol: Derl1
Name: derlin 1
Description: Predicted to have several functions, including enzyme binding activity; identical protein binding activity; and misfolded protein binding activity. Predicted to be involved in several processes, including ERAD pathway; endoplasmic reticulum unfolded protein response; and protein destabilization. Predicted to colocalize with the signal recognition particle and signal recognition particle receptor complex. Orthologous to human DERL1 (derlin 1); PARTICIPATES IN amyotrophic lateral sclerosis pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-phenylbutyric acid; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Der1-like domain family, member 1; derlin-1; LOC362912; RGD1311835; similar to RIKEN cDNA 1110021N07
Orthologs:
Homo sapiens (human) : DERL1 (derlin 1)  HGNC  Alliance
Mus musculus (house mouse) : Derl1 (Der1-like domain family, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Derl1 (derlin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DERL1 (derlin 1)
Canis lupus familiaris (dog) : DERL1 (derlin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Derl1 (derlin 1)
Sus scrofa (pig) : DERL1 (derlin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0797,737,176 - 97,759,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl797,737,178 - 97,759,852 (-)Ensembl
Rnor_5.0798,344,206 - 98,366,882 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4794,573,472 - 94,596,148 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1794,607,703 - 94,630,378 (-)NCBI
Celera786,177,037 - 86,199,719 (-)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Derl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311835
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.